KEGG ORTHOLOGY: K04574

ORTHOLOGY: K04574

Entry

K04574                      KO

Symbol

NEFH, NF-H

Name

neurofilament heavy polypeptide

Pathway

map05014

Amyotrophic lateral sclerosis

map05022

Pathways of neurodegeneration - multiple diseases

Disease

H00058

Amyotrophic lateral sclerosis (ALS)

H00264

Charcot-Marie-Tooth disease

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    K04574  NEFH, NF-H; neurofilament heavy polypeptide
   05022 Pathways of neurodegeneration - multiple diseases
    K04574  NEFH, NF-H; neurofilament heavy polypeptide
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K04574  NEFH, NF-H; neurofilament heavy polypeptide
Cytoskeleton proteins [BR:ko04812]
Eukaryotic cytoskeleton proteins
  Intermediate filaments
   Intermediate filaments
    Type IV
     K04574  NEFH, NF-H; neurofilament heavy polypeptide

Genes

HSA:	4744(NEFH)

PTR:	458741(NEFH)

PPS:	100988988(NEFH)

GGO:	101135442(NEFH)

PON:	100441417(NEFH)

NLE:	100598401(NEFH)

HMH:	116458504(NEFH)

MCC:	717705(NEFH)

MCF:	102145883(NEFH)

MTHB:

126963957

MNI:	105487262(NEFH)

CSAB:

103223139(NEFH)

CATY:

105575700(NEFH)

PANU:

101023307(NEFH)

TGE:	112632988(NEFH)

MLEU:

105550722(NEFH)

RRO:	104659243(NEFH)

RBB:	108517592(NEFH)

TFN:	117096154(NEFH)

PTEH:

111525390(NEFH)

CANG:

105506644(NEFH)

CJC:	100411710(NEFH)

SBQ:	101050157(NEFH)

CIMI:

108283352(NEFH) 108303587

CSYR:

103274854(NEFH)

MMUR:

105870907(NEFH)

LCAT:

123625814(NEFH)

PCOQ:

105810175(NEFH)

OGA:	100962779(NEFH)

MMU:	380684(Nefh)

MCAL:

110305910(Nefh)

MPAH:

110330208(Nefh)

RNO:	24587(Nefh)

MCOC:

116069362(Nefh)

ANU:	117712662(Nefh)

MUN:	110546108(Nefh)

CGE:	100753127(Nefh)

MAUA:

101838568(Nefh)

PROB:

127233634(Nefh)

PLEU:

114693998(Nefh)

MORG:

121436551(Nefh) 121459783

MFOT:

126500871

AAMP:

119805981(Nefh)

NGI:	103740466(Nefh)

HGL:	101704170(Nefh)

CPOC:

100716406(Nefh)

CCAN:

109681637(Nefh)

DORD:

105984165(Nefh)

DSP:	122097178(Nefh)

PLOP:

125347992(Nefh)

NCAR:

124990122

MMMA:

107154504(Nefh)

OCU:

100357177

OPI:	101529799(NEFH)

TUP:	102468700(NEFH) 102489354

CFA:	442940(NEFH)

CLUD:

112676783(NEFH)

VVP:	112909834(NEFH)

VLG:	121475227(NEFH)

NPO:	129508034(NEFH)

AML:	100465391(NEFH)

UMR:	103659273(NEFH)

UAH:	113245014(NEFH)

UAR:	123788256(NEFH)

ELK:

111160049

LLV:

125082446

MPUF:

101681011(NEFH)

MNP:	132023308(NEFH)

MLK:	131811556(NEFH)

NVS:	122903279(NEFH)

ORO:	101380389(NEFH)

EJU:	114225203(NEFH)

ZCA:	113912241(NEFH)

MLX:	118018699(NEFH)

NSU:	110592548(NEFH)

LWW:	102734149(NEFH)

FCA:	101087272(NEFH)

PYU:	121022603(NEFH)

PCOO:

112870413(NEFH)

PBG:	122470416(NEFH)

PVIV:

125148808(NEFH)

LRUF:

124518149

PTG:	102961590(NEFH)

PPAD:

109253560(NEFH)

PUC:

125913944

AJU:

106985448

HHV:	120226879(NEFH)

BTA:	528842(NEFH)

BOM:	102275464(NEFH)

BIU:	109571548(NEFH)

BBUB:

102398639(NEFH)

BBIS:

104980126(NEFH)

CHX:	102190538(NEFH)

OAS:	101107472(NEFH)

BTAX:

128062575(NEFH)

ODA:	120871643(NEFH)

CCAD:

122421322(NEFH)

MBEZ:

129542797(NEFH)

SSC:	100156492(NEFH)

CFR:	102505093(NEFH)

CBAI:

105066060(NEFH)

CDK:	105099464(NEFH)

VPC:	102533292(NEFH)

BACU:

103017782(NEFH)

BMUS:

118906641(NEFH)

LVE:	103083693(NEFH)

OOR:	101284970(NEFH)

DLE:	111162788(NEFH)

PCAD:

102980122(NEFH)

PSIU:

116739026(NEFH)

NASI:

112415179(NEFH)

ECB:	100064328(NEFH)

EPZ:	103548111(NEFH)

EAI:	106827382(NEFH)

MYB:	102252609(NEFH)

MYD:	102766068(NEFH)

MMYO:

118678250(NEFH)

MLF:	102427365(NEFH)

PKL:	118725550(NEFH)

EFUS:

103287139(NEFH)

MNA:	107526229(NEFH)

DRO:	112310836(NEFH)

SHON:

118991266(NEFH)

AJM:	119055130(NEFH)

PDIC:

114510430(NEFH)

PHAS:

123810775(NEFH)

MMF:	118639846(NEFH)

PPAM:

129087465(NEFH)

HAI:	109383106(NEFH)

RFQ:	117017613(NEFH)

PALE:

102885885(NEFH)

PGIG:

120601903(NEFH)

PVP:	105300929(NEFH)

RAY:	107520482(NEFH)

MJV:	108402484(NEFH)

TOD:	119245294(NEFH)

SARA:

101551412(NEFH)

SETR:

126030719(NEFH)

LAV:	100663647(NEFH)

TMU:

101351185

ETF:	101658747(NEFH)

DNM:	101447430(NEFH)

MDO:	100030735(NEFH)

SHR:	100913759(NEFH)

AFZ:

127545652

PCW:	110215325(NEFH)

OAA:	100087063(NEFH)

GGA:	417020(NEFH)

PCOC:

116228364(NEFH)

MGP:	100550205(NEFH)

CJO:	107321331(NEFH)

TPAI:

128083802(NEFH)

LMUT:

125701571(NEFH)

NMEL:

110406433(NEFH)

APLA:

101795792(NEFH)

ACYG:

106045515(NEFH)

CATA:

118252955(NEFH)

AFUL:

116495956(NEFH)

TGU:	100231150(NEFH)

LSR:	110474148(NEFH)

SCAN:

103818223(NEFH)

PMOA:

120510210(NEFH)

OTC:	121344457(NEFH)

PRUF:

121365063(NEFH)

GFR:	102038298(NEFH)

FAB:	101819308(NEFH)

OMA:	130259919(NEFH)

PHI:	102113316(NEFH)

PMAJ:

107211443(NEFH)

CCAE:

111936665(NEFH)

CCW:	104694993(NEFH)

CBRC:

103623806(NEFH)

ETL:	114071928(NEFH)

ZAB:	102065369(NEFH)

ACHL:

103802036(NEFH)

SVG:	106864791(NEFH)

MMEA:

130585096(NEFH)

HRT:	120760706(NEFH)

FPG:	101915834(NEFH)

FCH:	102048680(NEFH)

CLV:	102083909(NEFH)

EGZ:	104129873(NEFH)

NNI:	104010584(NEFH)

PCRI:

104035326(NEFH)

PLET:

104625890

EHS:	104503138(NEFH)

PCAO:

104039548(NEFH)

ACUN:

113486179(NEFH)

TALA:

104364151(NEFH)

AFOR:

103896491(NEFH)

ACHC:

115345387(NEFH)

HLE:	104829209(NEFH)

AGEN:

126040588

GCL:

127022873

CMAC:

104473222(NEFH)

MUI:	104544403(NEFH)

MNB:	103773108(NEFH)

OHA:	104331306(NEFH)

SHAB:

115614095(NEFH)

DPUB:

104308459(NEFH)

PGUU:

104469458

ACAR:

104517764

AVIT:

104276451(NEFH)

CVF:	104295994(NEFH)

RTD:	128917162(NEFH)

CUCA:

104056118(NEFH)

TEO:	104372796(NEFH)

AAM:

106485349

NPD:	112950383(NEFH)

DNE:	112994579(NEFH)

SCAM:

104149021(NEFH)

ASN:	102376665(NEFH)

AMJ:	102562405(NEFH)

CPOO:

109312934(NEFH)

GGN:	109290216(NEFH)

PSS:

102450392

CMY:	102946809(NEFH)

CCAY:

125622815(NEFH)

DCC:	119843819(NEFH)

CPIC:

101953853(NEFH)

TST:	117888194(NEFH)

CABI:

116815898(NEFH)

MRV:	120386497(NEFH)

ACS:	103280521(nefh)

ASAO:

132781216(NEFH)

PVT:	110082909(NEFH)

SUND:

121916605

PBI:

103062816

PMUR:

107288799(NEFH)

CTIG:

120303293(NEFH)

TSR:

106544989

PGUT:

117670741

APRI:

131185859(NEFH)

PTEX:

113450888(NEFH)

NSS:	113426718(NEFH)

VKO:	123032791(NEFH)

PMUA:

114586861(NEFH)

PRAF:

128404149(NEFH)

ZVI:	118076456(NEFH)

HCG:	128338134(NEFH)

GJA:	107105957(NEFH)

STOW:

125442707(NEFH)

EMC:	129340964(NEFH)

XLA:	108707066(nefh.S) 108715402(nefh.L)

XTR:	100101753(nefh)

NPR:	108798445(NEFH)

RTEM:

120939411(NEFH)

BBUF:

120990788(NEFH)

BGAR:

122933639(NEFH)

MUO:	115480799(NEFH)

GSH:	117365357(NEFH)

SGH:

CCAR:

AMEX:

CHAR:

TRU:	101076908(nefh)

TFS:

130526473

TNG:	GSTEN00015209G001

LCO:	104921296(nefh) 104935899

NCC:	104947809(cast)

TBEN:

117475956

CGOB:

115013870(nefh)

PGEO:

117451858

GACU:

117546217

EMAC:

134872947

ELY:	117252092 117272507

EFO:	125890537 125902544

PLEP:

121944285 121951291

SLUC:

116044908 116056653

ECRA:

117944923 117954742

ESP:	116689242(nefh) 116698836

PFLV:

114555453(nefh) 114565765

GAT:

120830128

PPUG:

119224489

AFB:	129089082 129101253

CLUM:

PSWI:

MSAM:

SCHU:

CUD:

ALAT:

MZE:	101477809(nefh)

ONL:	100691123(nefh)

OAU:	116331655 116332416

OLA:	101156679 101161248(nefh)

OML:	112148801 112151156

CSAI:

133450445 133452489 133457994 133459563 133460185

XMA:	102234528(nefh)

XCO:	114155089(nefh)

XHE:	116729430(nefh)

PRET:

103470377(nefh)

PFOR:

103142925(nefh)

PLAI:

106944583(nefh)

PMEI:

106920918(nefh)

GAF:

122828729

PPRL:

129372163

CVG:	107083651(nefh)

CTUL:

119786608 119787134

GMU:	124870498 124877280

NFU:	107393926(nefh)

KMR:

108234545

ALIM:

106521739(nefh)

NWH:

119413971

AOCE:

111568572 111584857(nefh)

MCEP:

125012058

CSEM:

103397106 103398198

POV:	109638155(nefh) 109645236

SSEN:

HHIP:

HSP:

SMAU:

LCF:

SDU:	111228042(nefh)

SLAL:

111660333(nefh) 111668372

XGL:	120798741 120805391

HCQ:	109514109(nefh)

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

110156696(nefh)

MALB:

109957016(nefh)

BSPL:

114844170 114862088

SJO:

128364444

SASA:

106580290 106584919 106608577

STRU:

115164403 115200240

OTW:	112247194 112248560 112263937

OMY:	110525767 110532767 110536145

OGO:	124033282 124036403

ONE:	115111683 115140148

OKI:	109880866 109895993

OKE:	118377430 118393297 127923976

SALP:

111957435 111973727

SNH:	120038941 120051349 120062897

CCLU:

121573751 121584929

ELS:	105025568(nefh)

SFM:	108927516(nefh)

PKI:	111861110(nefh)

AANG:

118237225

LOC:	102686090(nefh)

PSPA:

121297352 121300032

ARUT:

117428396

PSEX:

120541033

LCM:	102362710(NEFH)

CMK:

RTP:

CPLA:

HOC:

LERI:

BFO:

BBEL:

DCI:	103506421 103506519 103523720

FOC:

TPAL:

DMK:

PVM:

HAME:

MNZ:

SDM:

CRG:

MYI:

OBI:

SAPO:

MRT:

TVA:	TVAG_2v0565300

» show all

Reference

PMID:8621664

Authors

Mukai H, Toshimori M, Shibata H, Kitagawa M, Shimakawa M, Miyahara M, Sunakawa H, Ono Y

Title

PKN associates and phosphorylates the head-rod domain of neurofilament protein.

Journal

J Biol Chem 271:9816-22 (1996)
DOI:10.1074/jbc.271.16.9816

Sequence

[hsa:4744]

LinkDB

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