KEGG ORTHOLOGY: K04828

ORTHOLOGY: K04828

Entry

K04828                      KO

Symbol

ASIC2, ACCN1, BNAC1

Name

acid-sensing ion channel 2

Pathway

map04742

Taste transduction

map04750

Inflammatory mediator regulation of TRP channels

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09157 Sensory system
   04742 Taste transduction
    K04828  ASIC2, ACCN1, BNAC1; acid-sensing ion channel 2
   04750 Inflammatory mediator regulation of TRP channels
    K04828  ASIC2, ACCN1, BNAC1; acid-sensing ion channel 2
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04828  ASIC2, ACCN1, BNAC1; acid-sensing ion channel 2
Ion channels [BR:ko04040]
Ligand-gated channels
  Acid-sensing ion channel (ASIC)
   K04828  ASIC2, ACCN1, BNAC1; acid-sensing ion channel 2

Other DBs

GO:

0044736

TC:	1.A.6.1.2 1.A.6.1.8 1.A.6.1.9

Genes

HSA:

40(ASIC2)

PTR:	748244(ASIC2)

PPS:	100981428(ASIC2)

GGO:	101140748(ASIC2)

PON:

100450915

PPYG:

129017415(ASIC2)

NLE:	100592187(ASIC2)

HMH:

116474478

SSYN:

129469997(ASIC2)

MCC:	718204(ASIC2)

MCF:	102134637(ASIC2)

MTHB:

126939579

MNI:	105485175(ASIC2)

CSAB:

103242709(ASIC2)

CATY:

105589374(ASIC2)

PANU:

101006152(ASIC2)

TGE:	112609293(ASIC2)

MLEU:

105548704

RRO:	104669321(ASIC2)

RBB:	108541412(ASIC2)

TFN:

117067530

PTEH:

111520263(ASIC2)

CANG:

105508742(ASIC2)

CJC:	100413424(ASIC2)

SBQ:	101051729(ASIC2)

CIMI:

108313593

ANAN:

105715054(ASIC2)

CSYR:

103274745

MMUR:

105885863(ASIC2)

LCAT:

123620328(ASIC2)

ERUF:

138391356(ASIC2)

PCOQ:

105813532(ASIC2)

OGA:	100940541(ASIC2)

MMU:	11418(Asic2)

MCAL:

110305188(Asic2)

MPAH:

110331365(Asic2)

RNO:	25364(Asic2)

MCOC:

116079013(Asic2)

ANU:	117710723(Asic2)

ASYL:

127695143(Asic2)

MUN:	110549607(Asic2)

CGE:	100762972(Asic2)

MAUA:

101839927(Asic2)

PROB:

127218796(Asic2)

PLEU:

114691571(Asic2)

PMAV:

102917800(Asic2)

MORG:

121456446(Asic2)

MFOT:

126492351

AAMP:

119812670(Asic2)

CNL:	130877527(Asic2)

NGI:	103746071(Asic2)

HGL:	101697618(Asic2)

CPOC:

100717745

CCAN:

109702313(Asic2)

DORD:

105985644(Asic2)

DSP:	122120171(Asic2)

DMER:

138830662(Asic2)

PLOP:

125365461(Asic2)

NCAR:

124981247

SVUL:

306655820(ASIC2)

MMMA:

107155305(Asic2)

ITI:	101974004(Asic2)

SCIL:

308635777(ASIC2)

MAVE:

308274555(ASIC2)

OCU:

100343085

OPI:	101529224(ASIC2)

OCZ:	121169713(ASIC2)

TUP:	102501977(ASIC2)

GVR:	103595150(ASIC2)

CFA:	491150(ASIC2)

CLUD:

112655554(ASIC2)

VVP:	112918000(ASIC2)

VLG:	121473365(ASIC2)

NPO:	129509783(ASIC2)

AML:	100474094(ASIC2)

UMR:	103667269(ASIC2)

UAH:	113268979(ASIC2)

UAR:	123777051(ASIC2)

ELK:

111151502

LLV:

125088012

MPUF:

101685358(ASIC2)

MNP:	132003505(ASIC2)

MLK:

131816366

NVS:	122906453(ASIC2)

MMAQ:

308356647(ASIC2)

ORO:	101384607(ASIC2)

EJU:	114213735(ASIC2)

ZCA:	113907990(ASIC2)

MLX:	118025123(ASIC2)

MANO:

123854767(ASIC2)

NSU:	110592982(ASIC2)

FCA:	101096183(ASIC2)

PYU:	121017131(ASIC2)

PCOO:

112855293(ASIC2)

PBG:	122485219(ASIC2)

PVIV:

125152195(ASIC2)

LRUF:

124513599

LGF:	123603327(ASIC2)

AJU:

106985240

PTG:	102967183(ASIC2)

PPAD:

109251923(ASIC2)

PUC:

125926810

PLEZ:

122207358(ASIC2)

HHV:	120246417(ASIC2)

CCRU:

144219702(ASIC2)

BTA:	617930(ASIC2)

BOM:	102283391(ASIC2)

BIU:	109573181(ASIC2)

BJV:	133231813(ASIC2)

BBUB:

102410954(ASIC2)

BKE:	129649624(ASIC2)

BBIS:

105003993(ASIC2)

CHX:	102176638(ASIC2)

OAS:

101120341

OCAN:

138447236(ASIC2)

BTAX:

128065113(ASIC2)

CSUM:

138083369(ASIC2)

ODA:	120866667(ASIC2)

CCAD:

122449193(ASIC2)

MREE:

136149589(ASIC2)

OVR:	110137177(ASIC2)

MBEZ:

129540042(ASIC2)

SSC:	100628008(ASIC2)

CFR:	102514996(ASIC2)

CBAI:

105081291(ASIC2)

CDK:

105088227

VPC:	102540751(ASIC2)

BACU:

103014146(ASIC2)

BMUS:

118886141(ASIC2)

LVE:	103091096(ASIC2)

OOR:	101289310(ASIC2)

LALB:

132510986(ASIC2)

GMF:	115856111(ASIC2)

DDP:	132414998(ASIC2)

SCOO:

307177893(ASIC2)

PCRS:

137211734(ASIC2)

DLE:	111185916(ASIC2)

PCAD:

102977582(ASIC2)

PSIU:

116746250(ASIC2)

PPHC:

136138008(ASIC2)

NASI:

112394406(ASIC2)

HAMP:

307067841(ASIC2)

ECB:	100058355(ASIC2)

EPZ:	103562132(ASIC2)

EAI:	106844545(ASIC2)

MYB:	102259434(ASIC2)

MYD:	102752085(ASIC2)

MMYO:

118672312(ASIC2)

MLF:	102433804(ASIC2)

MDT:	132218363(ASIC2)

MYUM:

138995158(ASIC2)

PKL:	118728084(ASIC2)

EFUS:

103291682(ASIC2)

POTS:

308253645(ASIC2)

MNA:	107532588(ASIC2)

DRO:	112308603(ASIC2)

SHON:

118995231 119003544 119003581

AJM:	119036317(ASIC2)

PDIC:

114503934(ASIC2)

PHAS:

123817152(ASIC2)

MMF:	118634587(ASIC2)

PPAM:

129070256(ASIC2)

HAI:	109385076(ASIC2)

RFQ:	117013753(ASIC2)

RHII:

308488893(ASIC2)

PALE:

102897807(ASIC2)

PGIG:

120620909(ASIC2)

PVP:	105291965(ASIC2)

RAY:	107514649(ASIC2)

MJV:	108403534(ASIC2)

TOD:

119232511

SARA:

101544951(ASIC2)

SFUM:

130035379(ASIC2)

SETR:

126007947(ASIC2)

LAV:	100674921(ASIC2)

TMU:

101346851

ETF:	101640498(ASIC2)

DNM:	101444068(ASIC2)

MDO:	100022516(ASIC2)

GAS:

SHR:

AFZ:

PCW:

TVP:	118857096(ASIC2)

PBRV:

138162592(ASIC2)

MLAO:

141490141

OAA:	100682231(ASIC2)

TACU:

119934407(ASIC2)

GGA:	419945(ASIC2)

MGP:

100539998

CJO:	107325055(ASIC2)

TPAI:

128088728(ASIC2)

LMUT:

125684650(ASIC2)

NMEL:

110388460

APLA:

101795986(ASIC2)

AACU:

137844546(ASIC2)

OJA:	118178839(ASIC2)

BCLA:

308453077(LOC308453077)

ACYG:

106046904(ASIC2)

ABRC:

308181640(LOC308181640)

CATA:

118258237(ASIC2)

AFUL:

TGU:

LSR:

VMC:

VCHA:

AIB:

SCAN:

PMOA:

OTC:

PRUF:

ATRC:

MATE:

MAEN:

GFR:	102043709(ASIC2)

FAB:

OMA:

PHI:

PMAJ:

CCAE:

CCW:

CBRC:

ACOE:

ETL:	114068696 114069184

ZAB:	102063099 102066162 102073733

ZLE:

135458624

ACHL:

103801773(ASIC2)

SVG:

106858272

MMEA:

130583464 130587136

HRT:	120763664(ASIC2)

SATI:

136372347

CFAI:

136301925

CCIC:

134053040

NNT:	104402107(ASIC2)

SHAB:

115617883

POCC:

134165563

FPG:	101910536(ASIC2)

FCH:

FRS:

ACUN:

ANOC:

SURA:

TALA:

104360571(ASIC2)

ACHC:

115344830(ASIC2)

HALD:

104322626

HLE:	104827970(ASIC2)

AGEN:

126038989

HHAR:

128140794(ASIC2)

BBUT:

142034638(ASIC2)

GCL:

127026537

LDI:	104348377(ASIC2)

MNB:

DPUB:

PPUS:

IIN:

EGZ:

NNI:	104012265(ASIC2)

PARX:

142067850

PADL:

103926078(ASIC2)

AFOR:

FGA:

CBOR:

GSTE:

CBOY:

140662323(ASIC2)

MAME:

142419888

CLV:	102089830(ASIC2)

CNIC:

135998018

NMAY:

308049983(LOC308049983)

PGUU:

104470721

EHS:	104508363(ASIC2)

CUCA:

104054395(ASIC2)

PCUR:

138731202

TEO:

104373400

BREG:

104641446

GAME:

129195610(ASIC2)

OHA:

104338677

ACAR:

104521506

CEUR:

306728962(LOC306728962)

CPEA:

104390220

CVF:	104285372(ASIC2)

RTD:	128919414(ASIC2)

CRID:

134524341

LMIC:

141732765

NARQ:

141474642

AAM:	106497451(ASIC2)

AROW:

112962778

NPD:

112960233

TGT:

104576616

DNE:	112982799(ASIC2)

SCAM:

ASN:

AMJ:

CPOO:

PSS:

CIZ:	142002640(ASIC2)

CMY:	102940568(ASIC2)

CCAY:

125626865(ASIC2)

LKP:	140903808(ASIC2)

NDS:	141978443(ASIC2)

DCC:	119849132(ASIC2)

CPIC:

101944360

TST:	117869283(ASIC2)

EOB:

135894522

CABI:

116835034

MRV:

120384907

EMQ:	137148323(ASIC2)

ACS:	100565709(asic2)

ASAO:

132779619

PVT:

110074894

SUND:

121935410(ASIC2)

PBI:

103058480

PMUR:

107303027(ASIC2)

CTIG:

120316067

TSR:	106541169 106542356(ASIC2)

PGUT:

117664602(PRR29)

APRI:

131197186(PRR29)

PTEX:

113449429(ASIC2)

NSS:

113413479

VKO:	123030646 123031742(ASIC2)

PMUA:

114581749

PRAF:

128400102(ASIC2)

ZVI:	118095329(ASIC2)

HCG:	128329407(ASIC2)

GJA:

107105632

STOW:

125444483(ASIC2)

EMC:	129338522(ASIC2)

XLA:	108700864 108702568

XTR:	100492214(asic2)

NPR:

108790551

RTEM:

120918629

ACAT:

141114136(ASIC2)

PADS:

140333128(ASIC2)

BBUF:

121004778(ASIC2)

BGAR:

122940970(ASIC2)

DTC:	141096021(ASIC2)

HSQ:	130296724(ASIC2)

PCOB:

135055428(ASIC2)

PWL:	138299624(ASIC2)

MUO:

115481955

GSH:

117347047

DRE:	407669(asic2)

DAES:

130221510(asic2)

SRX:	107720021 107737939

SANH:

107654528 107674665

SGH:	107592342 107601227

CCAR:

109064124(asic2)

CAUA:

113047033 113069753 113075690 113075716 113097157

CGIB:

127943408 127952660

PTET:

122335901 122342074(asic2)

LROH:

127161793(asic2)

GRF:	141334035(asic2)

OMC:	131536432(asic2)

PPRM:

120489501(asic2)

SCEP:

307159567(asic2)

MAMB:

125272113(asic2)

CIDE:

127509024

CERY:

137012404(asic2)

MASI:

127450817 127451835

TROS:

130562196(asic2)

TDW:	130426137(asic2)

MANU:

129433390(asic2)

PDAB:

135737672(asic2)

IPU:

108259312

IFU:

128617685

PHYP:

113528377

SMEO:

124397146(asic2)

TFD:	113652181(asic2) 125140908

TVC:	132860712(asic2)

CGAR:

128544566(asic2)

NGRA:

132868832(asic2) 132869076

TRN:	134335801(asic2)

AMEX:

103044531

CMAO:

118820885(asic2)

CHAR:

105898679(asic2)

SPIL:

134077454(asic2)

ASAD:

121704558(asic2)

TRU:	101076875(asic2)

TFS:	130514947(asic2)

TNG:	GSTEN00027841G001

NCC:	104963987(asic2)

TBEN:

117493350(asic2)

CGOB:

115012093

PGEO:

117451140(asic2)

GACU:

117548278(asic2)

EMAC:

134877681(asic2)

ELY:	117268235(asic2)

EFO:	125879384(asic2)

PLEP:

121956223(asic2)

SLUC:

116063816(asic2)

SVIT:

144530556(asic2)

ECRA:

117957927(asic2)

ESP:	116702304(asic2)

PFLV:

114569470(asic2)

PFLT:

120574222(asic2)

GAT:	120827595(asic2)

PPUG:

119219947(asic2)

AFB:	129098050(asic2)

CLUM:

117735025(asic2)

PSWI:

130188223(asic2)

CANA:

137786524(asic2)

TBU:	306750058(asic2)

CVE:	137878192(asic2)

AMIR:

142944687(asic2)

MSAM:

119893337(asic2)

SCHU:

122868937(asic2)

EARM:

139299824(asic2)

CUD:	121529256(asic2)

SPUL:

138604030(asic2)

LMIX:

132954707(asic2)

HTC:	141809252(asic2)

ALAT:

119013662(asic2)

ASTR:

137609850(asic2)

PKLU:

139216846(asic2)

LCO:	104924998(asic2)

AMMM:

307262410(asic2)

MZE:	101482716(asic2)

ONL:	100707165(asic2)

OAU:	116309296(asic2)

OLA:	101175162(asic2)

OML:	112146414(asic2)

CSAI:

133421510(asic2)

XMA:	102217328(asic2)

XCO:	114159758(asic2)

XHE:	116735691(asic2)

PRET:

103469383(asic2)

PFOR:

103148767(asic2)

PLAI:

106953306(asic2)

PMEI:

106922357(asic2)

GAF:	122821719(asic2)

PPRL:

129373872(asic2)

CVG:

107096384

CTUL:

119790332(asic2)

GMU:	124863215 124863703

NFU:

107378549

KMR:	108237762(asic2)

ALIM:

106527407(asic2)

NWH:	119421870(asic2)

LTU:	140273495(asic2)

MCEP:

124998010(asic2)

AOCE:

111588898(asic2)

EJA:	138207825(asic2)

BFRE:

138631370(asic2)

LCF:	108880576(asic2)

CSEM:

103398759(asic2)

POV:	109633926(asic2)

SSEN:

122759823 122766066

SSOE:

131475496(asic2)

HHIP:

117766464(asic2)

HSP:	118123710(asic2)

PPLT:

128458429(asic2)

SMAU:

118288330(asic2)

SDU:	111217560(asic2)

SLAL:

111658417(asic2)

XGL:	120788196(asic2)

HCQ:	109532005(asic2)

SSCV:

125983663(asic2)

SBIA:

133514823(asic2)

PEE:	133415172(asic2)

PTAO:

133466043(asic2)

BPEC:

110169099

ENY:	140358225(asic2)

MALB:

109963125(asic2)

BSPL:

114859888(asic2)

SJO:	128378461(asic2)

SSCO:

133999516(asic2)

TTY:	137168082(asic2)

GMH:	115536993(asic2)

SASA:

106600659 106606842

STRU:

115171550(asic2) 115204081

OTW:	112236353 112237214 112259267

OMY:	110486711 110538663

OGO:	123999355 124015855

ONE:	115103519 115110819

OKI:	109880756 109897421

OKE:	118374090 118374456

OMM:	135554471 135555299(asic2)

OCLA:

139365053 139421523

SALP:

112071153

SNH:	120034425(asic2) 120044633

SFON:

129827847 129833514(asic2)

CCLU:

121568877 123486184 123486198

ELS:	109614601(asic2)

OEP:	134007080(asic2)

SFM:	108919299 108937349

PKI:	111834523 111856001

AANG:

118216712 118221040

AROT:

135244116 135247953

CCOG:

133115238 133122845

LOC:	102692504(asic2)

PSPA:

ARUT:

PSEX:

LCM:

CMK:

RTP:	109930581(asic2)

CPLA:

122539947

CPUN:

140465848

HOC:	132830723(asic2)

SCAU:

119954325(asic2)

LERI:

129710031 129710357(asic2)

HAKA:

140741463(asic2)

PMRN:

116940995

LRJ:

133344886

BFO:	118405165 118406155 118406173 118431729 118432798

BBEL:

109462465 109469466 109469701 109477848

CIN:

100179324

SCLV:

120342861

CLEP:

143460802

SPU:	100887843 762584

LPIC:

129257462 129261331 129261556 129280557

LVG:	121406611 121410260 121411484 121413643 121425588 121425850 121429917

AJJ:	139966911 139979640 139980119

APLC:

110973302 110977200 110985924 110986456 110986461

ARUN:

117288843 117293540 117293669 117293823 117294012 117303516

AAMU:

139933948 139934414 139935939 139936182 139936262 139936365 139945441

AFIL:

140136607 140139047 140139048 140141497 140144756 140151909 140151921 140160123 140160238 140161101 140161102 140161104 140169722 140170980

PFLL:

139130417 139130872 139131610 139136111 139136729 139136731 139136732 139136738

AARA:

AMER:

ASTE:

CNS:

BCOO:

MSEX:

PPOT:

OFU:

DMK:

PCLA:

ESN:

RSAN:

119381648 119381652 119382101 119382102 119394594 119399087

GOE:

PVUL:

LSAX:

GAE:

HRF:	124133668 124136686 124136726

HRJ:	124255461 124262572 124289891 124289902

HASI:

137279017 137279018 137279019 137279020 137279021 137279022 137279024 137279025

HCRA:

CRG:

CANU:

MYI:

PMAX:

AIRR:

YBA:

OSN:

LJP:

LAK:	106150550 106166953 106167526 106170322 106172835 106173584 106176599 112041460

NVE:	5500141 5505651 5508466 5510410 5511556 5513120 5520559 5521863

EPA:	110232782 110232800 110240002 110241600 110244851 110244853 110250071 110250081 110250156 110251498 110253656 110253765

ATEN:

116303424

ADF:

107346905

AMIL:

114958332 114967758 114967991 114968007 122956131

MCAZ:

138041630 138051945 138052924 138059590 138060559

MFOO:

137969860 137970261 137995864 137997424 137997428 137997429 137997430 137997431 137997432 138008532 138013189

PDAM:

113666687 113669998 113670068 113680653 113681154 113681156 113681159 113681160 113681161

SPIS:

111321568 111321577 111321578 111321579 111321608 111321624 111321655 111324737 111334490 111334491 111335374 111337973

XEN:

124440164

HSY:

130644323

RES:

135696260

TAD:	TRIADDRAFT_57842 TRIADDRAFT_58144

» show all

Reference

PMID:8631835

Authors

Waldmann R, Champigny G, Voilley N, Lauritzen I, Lazdunski M

Title

The mammalian degenerin MDEG, an amiloride-sensitive cation channel activated by mutations causing neurodegeneration in Caenorhabditis elegans.

Journal

J Biol Chem 271:10433-6 (1996)
DOI:10.1074/jbc.271.18.10433

Sequence

[rno:25364]

LinkDB

DBGET integrated database retrieval system