KEGG ORTHOLOGY: K04905

ORTHOLOGY: K04905

Entry

K04905                      KO

Symbol

KCNH2, KV11.1

Name

potassium voltage-gated channel Eag-related subfamily H member 2

Disease

H00720

Long QT syndrome

H00725

Short QT syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04905  KCNH2, KV11.1; potassium voltage-gated channel Eag-related subfamily H member 2
Ion channels [BR:ko04040]
Voltage-gated cation channels
  Potassium channel, voltage-gated (Kv)
   K04905  KCNH2, KV11.1; potassium voltage-gated channel Eag-related subfamily H member 2

Other DBs

GO:

0005249

TC:	1.A.1.20.1

Genes

HSA:	3757(KCNH2)

PTR:	463894(KCNH2)

PPS:	100974309(KCNH2)

GGO:	101147613(KCNH2) 115932897

PON:	100447585(KCNH2)

NLE:	100592116(KCNH2)

HMH:	116814532(KCNH2)

MCC:	714174(KCNH2)

MCF:	102142329(KCNH2)

MTHB:

126951571

MNI:	105474899(KCNH2)

CSAB:

103227232(KCNH2)

CATY:

105584733(KCNH2)

PANU:

101024534(KCNH2)

TGE:	112620507(KCNH2)

MLEU:

105542710

RRO:	104675392(KCNH2)

RBB:	108532524(KCNH2)

TFN:	117072671(KCNH2)

PTEH:

111551476(KCNH2)

CANG:

105511326(KCNH2)

CJC:	100413935(KCNH2)

SBQ:	101033910(KCNH2)

CIMI:

108297782(KCNH2)

CSYR:

103275299(KCNH2)

MMUR:

105883169(KCNH2)

LCAT:

123647520(KCNH2)

PCOQ:

105824584(KCNH2)

OGA:	100957438(KCNH2)

MMU:	16511(Kcnh2)

MCAL:

110294821(Kcnh2)

MPAH:

110316337(Kcnh2)

RNO:	117018(Kcnh2)

MCOC:

116097542(Kcnh2)

ANU:	117720612(Kcnh2)

MUN:	110562559(Kcnh2)

CGE:	100770245(Kcnh2)

MAUA:

101838552(Kcnh2)

PROB:

127235668(Kcnh2)

PLEU:

114700089(Kcnh2)

MORG:

121439992(Kcnh2)

MFOT:

126489432

AAMP:

119807666(Kcnh2)

NGI:	103745302(Kcnh2)

HGL:	101711977(Kcnh2)

CPOC:

100135563(Kcnh2)

CCAN:

109694441(Kcnh2)

DORD:

105993878(Kcnh2)

DSP:	122105890(Kcnh2)

PLOP:

125347315(Kcnh2)

NCAR:

124991698

MMMA:

107148939(Kcnh2)

OCU:	100009242(KCNH2) 127493710

OPI:	101521097(KCNH2)

TUP:	102474366(KCNH2)

GVR:	103585107(KCNH2)

CFA:	403761(KCNH2)

CLUD:

112663837(KCNH2)

VVP:	112916252(KCNH2)

VLG:	121489827(KCNH2)

NPO:	129516209(KCNH2)

AML:	100467726(KCNH2)

UMR:	103660996(KCNH2)

UAH:	113241425(KCNH2)

UAR:	123789632(KCNH2)

ELK:

111154435

LLV:

125081328

MPUF:

101673995(KCNH2)

MNP:	132015573(KCNH2)

MLK:	131829936(KCNH2)

NVS:	122905197(KCNH2)

ORO:	101381878(KCNH2)

EJU:	114198020(KCNH2)

ZCA:	113911719(KCNH2)

MLX:	118026799(KCNH2)

NSU:	110582756(KCNH2)

LWW:

102734349

FCA:	101081621(KCNH2)

PYU:	121022900(KCNH2)

PCOO:

112866503(KCNH2)

PBG:	122488526(KCNH2)

PVIV:

125161056(KCNH2)

LRUF:

124524041

PTG:	102967235(KCNH2)

PPAD:

109252363

PUC:

125930301

AJU:

106969578

HHV:	120230956(KCNH2)

BTA:	539971(KCNH2)

BOM:

102275782

BIU:	109557792(KCNH2)

BBUB:

102408998(KCNH2)

BBIS:

105001193(KCNH2)

CHX:	102185061(KCNH2)

OAS:	101106315(KCNH2)

BTAX:

128046418(KCNH2)

ODA:	120877878(KCNH2)

MBEZ:

129552778(KCNH2)

SSC:	100523293(KCNH2)

CFR:	102524043(KCNH2)

CDK:	105105697(KCNH2)

VPC:

116278562

BACU:

103017562(KCNH2)

BMUS:

118901144(KCNH2)

LVE:	103073918(KCNH2)

OOR:	101280095(KCNH2)

DLE:	111176854(KCNH2)

PCAD:

102985519(KCNH2)

PSIU:

116759639(KCNH2)

NASI:

112405908(KCNH2)

ECB:	100064000(KCNH2)

EPZ:	103540940(KCNH2) 103545107

EAI:	106823376(KCNH2)

MYB:	102256858(KCNH2)

MYD:	102755110(KCNH2)

MMYO:

118679439(KCNH2)

MLF:	102437228(KCNH2)

PKL:	118704764(KCNH2)

EFUS:

103301762(KCNH2)

MNA:	107524934(KCNH2)

DRO:	112308284(KCNH2)

SHON:

118975522(KCNH2)

AJM:	119039280(KCNH2)

PDIC:

114507834(KCNH2)

PHAS:

123817997(KCNH2)

MMF:	118619816(KCNH2)

PPAM:

129086756(KCNH2)

HAI:	109389627(KCNH2)

RFQ:	117018299(KCNH2)

PALE:

102891558(KCNH2)

PGIG:

120601490(KCNH2)

PVP:	105303768(KCNH2)

RAY:	107520318(KCNH2)

MJV:	108391840(KCNH2)

TOD:	119248284(KCNH2)

SARA:

101546763(KCNH2)

SETR:

126014124(KCNH2)

LAV:	100668634(KCNH2)

TMU:

101356533

ETF:	101659826(KCNH2)

DNM:	101433287(KCNH2)

MDO:	100017968(KCNH2)

GAS:	123249862(KCNH2)

SHR:	100915622(KCNH2)

AFZ:

127564035

PCW:	110201971(KCNH2)

OAA:	100077925(KCNH2)

GGA:	100858122(KCNH2)

PCOC:

116242819(KCNH2)

MGP:	100545192(KCNH2)

CJO:	107308679(KCNH2)

TPAI:

128086209(KCNH2)

LMUT:

125696124(KCNH2)

NMEL:

110390702(KCNH2)

APLA:

119715418(KCNH2)

CATA:

118251869(KCNH2)

AFUL:

116486481(KCNH2)

TGU:	115494066(KCNH2)

LSR:	110475120(KCNH2)

PMOA:

120510591(KCNH2)

OTC:	121334885(KCNH2)

PRUF:

121356984

OMA:	130249120(KCNH2)

PHI:	102101246(KCNH2)

PMAJ:

107215440(KCNH2)

ETL:

114071763

SVG:	106861782(KCNH2)

MMEA:

130574582(KCNH2)

FPG:	101918140(KCNH2)

FCH:	102057188(KCNH2)

CLV:

102084420

NNI:

104015818

ACUN:

113477545(KCNH2)

AFOR:

103896024

ACHC:

115338953(KCNH2)

HLE:	104829377(KCNH2)

AGEN:

126037596

SHAB:

115610843(KCNH2)

DPUB:

104298519(KCNH2)

AAM:

106500476

AROW:

112973594(KCNH2)

NPD:

112956258

DNE:	112994719(KCNH2)

ASN:	102380953(KCNH2)

AMJ:	102560583(KCNH2)

CPOO:

109308566(KCNH2)

CMY:	102936775(KCNH2)

CCAY:

125632957(KCNH2)

DCC:	119850721(KCNH2)

CPIC:

101932317(KCNH2)

MRV:	120397755(KCNH2)

ACS:	100557791(kcnh2)

ASAO:

132779095(KCNH2)

PVT:	110082586(KCNH2)

SUND:

121935314(KCNH2)

PBI:

103060190

PMUR:

107299027(KCNH2)

CTIG:

120320271(KCNH2)

TSR:	106539088(KCNH2)

PGUT:

117669220(KCNH2)

APRI:

131196505(KCNH2)

VKO:	123019559(KCNH2)

PMUA:

114607213(KCNH2)

PRAF:

128423989(KCNH2)

ZVI:	118092033(KCNH2)

HCG:	128329347(KCNH2)

GJA:	107108214(KCNH2)

STOW:

125440967(KCNH2)

EMC:	129337719(KCNH2)

XLA:	108704616 108719641

XTR:	100491983(kcnh6)

NPR:

108803368

RTEM:

120941751(KCNH2)

BBUF:

121000745(KCNH2)

BGAR:

122938508 122938897(KCNH2)

MUO:	115465217(KCNH2)

GSH:	117354472(KCNH2)

DRE:	100463518(kcnh2b) 563802(kcnh2a)

SRX:	107713389 107718079 107722642 107753076

SANH:

107676096 107676812 107687170 107688523

SGH:	107560355 107586123 107589806

CCAR:

109053133 109071191 109100896

CAUA:

113042652 113045880 113068778 113116659

CGIB:

127946297 127950351 128013494 128028446

PTET:

122330002(kcnh2b) 122346433 122357099(kcnh2a)

LROH:

127155449(kcnh2b) 127176953(kcnh2a)

OMC:	131532652(kcnh2a) 131533314(kcnh2b)

PPRM:

120467777(kcnh2b) 120483177(kcnh2a)

RKG:	130070891(kcnh2a) 130096920(kcnh2b)

MAMB:

125251325(kcnh2a) 125257779(kcnh2b)

CIDE:

127504691

MASI:

127431505 127434803 127440293 127442836

TROS:

130546928 130553829(kcnh2a)

TDW:	130413511(kcnh2b) 130417563(kcnh2a)

MANU:

129426677(kcnh2b) 129442282(kcnh2a)

IPU:	108277613(kcnh2a) 108279292(kcnh2b)

IFU:	128614228 128621752(kcnh2a)

PHYP:

113526503 113532654

SMEO:

124384316(kcnh2b) 124394096(kcnh2a)

TFD:	113643443(kcnh2a) 113644761(kcnh2b)

TVC:	132845588(kcnh2b) 132857965(kcnh2a)

AMEX:

103033764 103039353

CMAO:

118820982(kcnh2b) 118827438(kcnh2a)

EEE:	113572971 113574680

CHAR:

105890072(kcnh2b) 105900464(kcnh2a)

TRU:	101064060 101069094

TFS:	130513885(kcnh2b) 130539294

TNG:	GSTEN00002712G001 GSTEN00016707G001 GSTEN00022050G001 GSTEN00033661G001

LCO:	104927593(kcnh2)

NCC:

104949918

TBEN:

117479633(kcnh2b)

CGOB:

115025312(kcnh2)

PGEO:

117466069(kcnh2b)

GACU:

117561199

EMAC:

134865971 134883978(kcnh2b)

ELY:	117264571(kcnh2b) 117271561

EFO:	125881961(kcnh2b)

PLEP:

121951861 121960481(kcnh2b)

SLUC:

116040897 116048946(kcnh2b)

ECRA:

117938250(kcnh2b) 117954060

ESP:	116672153 116699831

PFLV:

114548857 114565226

GAT:	120811519(kcnh2b) 120815745

PPUG:

119198589(kcnh2b) 119209928

AFB:	129088771 129110427(kcnh2b)

CLUM:

117746858 117749441(kcnh2b)

PSWI:

130206017

MSAM:

119906195(kcnh2b)

SCHU:

122866574(kcnh2b)

CUD:	121519551 121527390(kcnh2b)

ALAT:

119008920(kcnh2b) 119011619

MZE:	101467662 112433055

ONL:

102075990

OAU:	116331871(kcnh2b)

OLA:

101172692

OML:	112151588(kcnh2b)

CSAI:

133423703(kcnh2b)

XMA:	102235827(kcnh2)

XCO:	114136914(kcnh2)

XHE:

116711711

PRET:

103482352

PFOR:

103143936(kcnh2)

PLAI:

106956996(kcnh2)

PMEI:

106922108

GAF:	122824127(kcnh2b)

PPRL:

129364675(kcnh2b)

CVG:	107086506(kcnh2) 107101342

CTUL:

119799315 119799529

GMU:

124858484

KMR:	108246411(kcnh2b)

ALIM:

106528596

NWH:

119426478

AOCE:

111577585 111578706

MCEP:

124995408(kcnh2b)

CSEM:

103376881 103396561

POV:	109638359 109644240

SSEN:

122777972 122781979

HHIP:

117754224(kcnh2b) 117777909

HSP:	118098888(kcnh2b) 118117217

SMAU:

118291289(kcnh2b) 118310617

LCF:	108881553(kcnh2b)

SDU:	111228202(kcnh2) 111239141

SLAL:

111653443 111657041

XGL:	120789775(kcnh2b) 120798915

HCQ:	109518112 109524144

SSCV:

125986150

SBIA:

133492594(kcnh2b)

PEE:	133396205(kcnh2b)

PTAO:

133470294(kcnh2b)

BPEC:

110165554(kcnh2) 110174565

MALB:

109971286

BSPL:

114844362 114854853(kcnh2b)

SJO:	128382214(kcnh2b)

SASA:

106569206 106574461 106579665 106590277 106599276

STRU:

115148677 115157089 115169690 115195628

OTW:	112227374 112227829(kcnh2b) 112260535

OMY:	110489794(kcnh2b) 110508666 110530392 110536544

OGO:	123990428 124009761 124017779 124040921

ONE:	115101574 115114849 115120188 115131056

OKI:	109871535 109874708 109879760 109900175

OKE:	118371656(kcnh2b) 118375129 118394723 118402043

SALP:

111953880 111957009 111979618

SNH:	120019828 120027914 120050649(kcnh2b) 120055278

CCLU:

121535280 121549718 121568668(kcnh2b) 121581312

ELS:	105019485(kcnh2) 105024264

SFM:	108934016 108935396(kcnh2)

PKI:	111840147 111859601

AANG:

118224622(kcnh2b) 118233562

LOC:	102689405(kcnh2)

PSPA:

121312821(kcnh2b) 121314293

ARUT:

117394695 117399214

PSEX:

120529744(kcnh2b)

LCM:	102354174(KCNH2)

CPLA:

122548788

HOC:	132815261(kcnh2b) 132830737(kcnh6a)

LERI:

129710241(kcnh6a)

PMRN:

LRJ:

BFO:

CIN:

SPU:	115919002 585010 757031

LPIC:

129266474

APLC:

110983883

AJC:	117118698 117125105

SKO:

100371738

DME:	Dmel_CG3182(sei)

DER:

6548123

DSE:

6613006

DSI:	Dsimw501_GD11824(Dsim_GD11824)

DYA:	Dyak_GE14365

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:	119607449 119611689

GFS:

ECOE:

CLON:

ACOZ:

AARA:

ASTE:

AFUN:

AAG:

AALB:

CPII:

CNS:

AME:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

CSET:

AGB:

LDC:

NVL:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_208086

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

PGW:

CCRN:

API:

DNX:

AGS:

RMD:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

PHU:	Phum_PHUM193530

FOC:

ZNE:

CSEC:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_39704

PVM:

MNZ:

HAZT:

EAF:

TCF:

PPOI:

DSV:

RSAN:

TUT:

DPTE:

DFR:

CSCU:

111614820 111619450 111642178

PTEP:

107443883 107448675

LPOL:

106459387

CEL:	CELE_C30D11.1(unc-103)

CBR:	CBG_20190(Cbr-unc-103.2)

CRQ:	GCK72_008889

NAI:	NECAME_13777

LOA:	LOAG_18296

TSP:

Tsp_11330

LGI:	LOTGIDRAFT_144428

PCAN:

112555382 112565295

SMM:	Smp_161140

OVI:	T265_06953

ATEN:

PDAM:

DGT:

XEN:

HMG:

HSY:

TAD:	TRIADDRAFT_23112

» show all

Reference

PMID:18559421

Authors

Guasti L, Crociani O, Redaelli E, Pillozzi S, Polvani S, Masselli M, Mello T, Galli A, Amedei A, Wymore RS, Wanke E, Arcangeli A

Title

Identification of a posttranslational mechanism for the regulation of hERG1 K+ channel expression and hERG1 current density in tumor cells.

Journal

Mol Cell Biol 28:5043-60 (2008)
DOI:10.1128/MCB.00304-08

Sequence

[hsa:3757]

LinkDB

DBGET integrated database retrieval system