KEGG   ORTHOLOGY: K05063
Entry
K05063                      KO                                     
Symbol
IL12RB1, CD212
Name
interleukin 12 receptor beta-1
Pathway
map04060  Cytokine-cytokine receptor interaction
map04630  JAK-STAT signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map05200  Pathways in cancer
map05321  Inflammatory bowel disease
Disease
H00089  IFN-gamma/IL-12 axis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
   04659 Th17 cell differentiation
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
   04090 CD molecules
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL6/12 receptor family
   K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
CD molecules [BR:ko04090]
 Proteins
  K05063  CD212, IL12RB1; interleukin 12 receptor, beta 1
Genes
HSA: 3594(IL12RB1)
PTR: 455851(IL12RB1)
GGO: 101134933(IL12RB1)
PON: 100435478(IL12RB1)
NLE: 100605040(IL12RB1)
HMH: 116478688(IL12RB1)
MCC: 574199(IL12RB1)
MCF: 102143359(IL12RB1)
MTHB: 126942203
MNI: 105488730(IL12RB1)
CSAB: 103234165(IL12RB1)
CATY: 105601688(IL12RB1)
PANU: 101015690(IL12RB1)
TGE: 112612745(IL12RB1)
MLEU: 105547587(IL12RB1)
RRO: 104680608(IL12RB1)
RBB: 108534277(IL12RB1)
TFN: 117074814(IL12RB1)
PTEH: 111554319(IL12RB1)
CANG: 105500332(IL12RB1)
CJC: 100399291(IL12RB1)
SBQ: 101032718(IL12RB1)
CIMI: 108284619(IL12RB1)
CSYR: 103251617(IL12RB1)
LCAT: 123639640(IL12RB1)
PCOQ: 105818120(IL12RB1)
OGA: 100962079(IL12RB1)
MMU: 16161(Il12rb1)
MCAL: 110300406(Il12rb1)
MPAH: 110336813(Il12rb1)
RNO: 171333(Il12rb1)
MCOC: 116069495(Il12rb1)
ANU: 117721951(Il12rb1)
MUN: 110549207(Il12rb1)
CGE: 100763378(Il12rb1)
MAUA: 101843816(Il12rb1)
PROB: 127217218(Il12rb1)
MORG: 121462539(Il12rb1)
MFOT: 126491780
AAMP: 119813538(Il12rb1)
NGI: 103726945(Il12rb1)
HGL: 101702338(Il12rb1)
CPOC: 100715293(Il12rb1)
CCAN: 109699530(Il12rb1)
DSP: 122100857(Il12rb1)
PLOP: 125347718(Il12rb1)
NCAR: 124969200
MMMA: 107145059(Il12rb1)
OPI: 101526357(IL12RB1)
TUP: 102470262(IL12RB1)
GVR: 103593685(IL12RB1)
CFA: 484828(IL12RB1)
CLUD: 112666733(IL12RB1)
VVP: 112913171(IL12RB1)
VLG: 121495556(IL12RB1)
NPO: 129522001(IL12RB1)
AML: 100474774(IL12RB1)
UMR: 103674947(IL12RB1)
UAH: 113256701(IL12RB1)
UAR: 123779817(IL12RB1)
ELK: 111144102
LLV: 125082312
MPUF: 101682913(IL12RB1)
MNP: 132011168(IL12RB1)
MLK: 131823752(IL12RB1)
NVS: 122910727(IL12RB1)
ORO: 101372587(IL12RB1)
EJU: 114196409(IL12RB1)
ZCA: 113918270(IL12RB1)
MLX: 118005254(IL12RB1)
NSU: 110574499(IL12RB1)
LWW: 102726737(IL12RB1)
FCA: 101093085(IL12RB1)
PYU: 121011001(IL12RB1)
PCOO: 112852391(IL12RB1)
PBG: 122487088(IL12RB1)
PVIV: 125161092(IL12RB1)
LRUF: 124523112
PTG: 102959877(IL12RB1)
PPAD: 109247602(IL12RB1)
PUC: 125929233
AJU: 106969152
HHV: 120239142(IL12RB1)
BTA: 524299(IL12RB1)
BOM: 102286576(IL12RB1)
BIU: 109561420(IL12RB1)
BBUB: 102403765(IL12RB1)
BBIS: 104992690(IL12RB1)
CHX: 102172253(IL12RB1)
OAS: 101110054(IL12RB1)
BTAX: 128051171(IL12RB1)
ODA: 120864211(IL12RB1)
CCAD: 122440735(IL12RB1)
MBEZ: 129559429(IL12RB1)
SSC: 100271900(IL12RB1)
CFR: 102512953(IL12RB1)
CBAI: 105082567(IL12RB1)
CDK: 105101865(IL12RB1)
VPC: 102543681(IL12RB1)
BACU: 103009591(IL12RB1)
BMUS: 118892929(IL12RB1)
LVE: 103081698(IL12RB1)
OOR: 101281920(IL12RB1)
DLE: 111166653(IL12RB1)
PCAD: 102991223(IL12RB1)
PSIU: 116751673(IL12RB1)
NASI: 112414745(IL12RB1)
ECB: 100146965(IL12RB1)
EPZ: 103561544(IL12RB1)
EAI: 106825010(IL12RB1)
MYB: 102253710(IL12RB1)
MYD: 102769690(IL12RB1)
MMYO: 118659126(IL12RB1)
MLF: 102421801(IL12RB1)
PKL: 118726119(IL12RB1)
EFUS: 103299579(IL12RB1)
MNA: 107535370(IL12RB1)
DRO: 112305028(IL12RB1)
SHON: 118975125(IL12RB1)
AJM: 119046827(IL12RB1)
PDIC: 114503736(IL12RB1)
PHAS: 123828311(IL12RB1)
MMF: 118643823(IL12RB1)
PPAM: 129074842(IL12RB1)
HAI: 109382356(IL12RB1)
RFQ: 117037501(IL12RB1)
PALE: 102878946(IL12RB1)
PGIG: 120606547(IL12RB1)
PVP: 105296672(IL12RB1)
RAY: 107521689(IL12RB1)
MJV: 108383562
TOD: 119242236(IL12RB1)
SARA: 101552662(IL12RB1)
SETR: 126030201(IL12RB1)
LAV: 100672726(IL12RB1)
TMU: 101351266
ETF: 101642724(IL12RB1)
DNM: 101432301(IL12RB1)
MDO: 103105099(IL12RB1)
GAS: 123256795(IL12RB1)
SHR: 105749415(IL12RB1)
AFZ: 127545229
PCW: 110223476(IL12RB1)
OAA: 100079998(IL12RB1)
GGA: 101749221(IL12RB1)
PCOC: 116235710(IL12RB1)
MGP: 104915407
CJO: 107325690(IL12RB1)
TPAI: 128088969(IL12RB1)
LMUT: 125684956(IL12RB1)
NMEL: 110388754(IL12RB1)
APLA: 101797086(IL12RB1)
ACYG: 106044936(IL12RB1)
CATA: 118258763(IL12RB1)
AFUL: 116499245(IL12RB1)
TGU: 115490890(IL12RB1)
SCAN: 103822011(IL12RB1)
PMOA: 120498080(IL12RB1)
OTC: 121341493(IL12RB1)
PRUF: 121361617(IL12RB1)
GFR: 102037576(IL12RB1)
FAB: 101812402(IL12RB1)
OMA: 130264487(IL12RB1)
PHI: 102100998(IL12RB1)
PMAJ: 107215365(IL12RB1)
CCAE: 111940322(IL12RB1)
CCW: 104697031(IL12RB1)
CBRC: 103622146(IL12RB1)
ETL: 114069506(IL12RB1)
ACHL: 103803564(IL12RB1)
SVG: 106857058(IL12RB1)
MMEA: 130586290(IL12RB1)
HRT: 120763452(IL12RB1)
FPG: 101911543(IL12RB1)
FCH: 102051332(IL12RB1)
CLV: 102098000(IL12RB1)
EGZ: 104135651(IL12RB1)
NNI: 104018782(IL12RB1)
ACUN: 113489367(IL12RB1)
TALA: 116962006(IL12RB1)
HLE: 104828560(IL12RB1)
AGEN: 126041453
GCL: 127025672
MUI: 104539641(IL12RB1)
SHAB: 115618217(IL12RB1)
DPUB: 104300794(IL12RB1)
ACAR: 104523939(IL12RB1)
CPEA: 104388882(IL12RB1)
RTD: 128900689(IL12RB1)
CUCA: 104060991(IL12RB1)
BRHI: 104497893(IL12RB1)
AROW: 112966747(IL12RB1)
NPD: 112943885(IL12RB1)
ASN: 102378143(IL12RB1)
AMJ: 106737527(IL12RB1)
CPOO: 109312419(IL12RB1)
GGN: 109295058(IL12RB1)
PSS: 102461655(IL12RB1)
CMY: 114022446(IL12RB1)
CCAY: 125627296(IL12RB1)
DCC: 119848357(IL12RB1)
CPIC: 101941042(IL12RB1)
TST: 117869099(IL12RB1)
CABI: 116826233(IL12RB1)
MRV: 120391765(IL12RB1)
ACS: 103282283(il12rb1)
PVT: 110072563(IL12RB1)
SUND: 121917660(IL12RB1)
PBI: 112540224(IL12RB1)
PMUR: 114922203(IL12RB1)
CTIG: 120305983(IL12RB1)
TSR: 106543464(IL12RB1)
PGUT: 117677413(IL12RB1)
APRI: 131188169(IL12RB1)
PTEX: 113434956(IL12RB1)
NSS: 113414091(IL12RB1)
PMUA: 114588688(IL12RB1)
ZVI: 118085976(IL12RB1)
HCG: 128343758(IL12RB1)
EMC: 129331198(IL12RB1)
XLA: 108720006
XTR: 100496683(il12rb1)
RTEM: 120916023(IL12RB1)
BBUF: 120989609(IL12RB1)
BGAR: 122927988(IL12RB1)
MUO: 115480942(IL12RB1)
GSH: 117365049(IL12RB1)
DRE: 101883301(si:dkey-13m1.2)
SRX: 107723841 107753824
SANH: 107656097 107692236
SGH: 107572942 107602771
CCAR: 109048193 109069661
CAUA: 113055079 113110655 113111244
CGIB: 127967801 128022516
PTET: 122353569(il12rb1)
LROH: 127172847(il12rb1)
OMC: 131548971(il12rb1)
PPRM: 120466688(il12rb1) 120466985
RKG: 130086609 130086613(il12rb1)
MAMB: 125256342(il12rb1)
CIDE: 127522701
MASI: 127426556 127428143
TROS: 130571500(il12rb1)
TDW: 130410006(il12rb1)
MANU: 129428071(il12rb1)
IPU: 108270768(il12rb1)
IFU: 128614141(il12rb1)
PHYP: 113528465
SMEO: 124390823(il12rb1)
TFD: 113657680(il12rb1)
TVC: 132851683(il12rb1)
AMEX: 103028625
CMAO: 118819294(il12rb1)
CHAR: 122128527(il12rb1)
TRU: 105417954
TFS: 130528974 130529063
LCO: 104920404
NCC: 104959360(il12rb1)
TBEN: 117495234 117495267
CGOB: 115006624(il12rb1) 115007368
PGEO: 117444843 117444857
GACU: 117544246 117544252
EMAC: 134869481 134869719
ELY: 117253726(il12rb1)
EFO: 125896337(il12rb1)
PLEP: 121962182(il12rb1)
SLUC: 116055332(il12rb1)
ECRA: 117950930(il12rb1)
ESP: 116696013(il12rb1)
PFLV: 114561835
GAT: 120824464(il12rb1)
PPUG: 119217278(il12rb1)
AFB: 129094910(il12rb1)
CLUM: 117729133(il12rb1)
PSWI: 130194112(il12rb1)
MSAM: 119900530(il12rb1)
SCHU: 122878160(il12rb1)
CUD: 121511673(il12rb1)
ALAT: 119028303(il12rb1)
MZE: 101472333
ONL: 102077946
OAU: 116328448(il12rb1)
OLA: 105353921
OML: 112150641(il12rb1)
CSAI: 133458782(il12rb1)
XMA: 111609789(il12rb1)
XCO: 114151489(il12rb1)
XHE: 116725976(il12rb1)
PRET: 103463422
PFOR: 103129869(il12rb1)
PLAI: 106937760(il12rb1)
PMEI: 106914013(il12rb1)
GAF: 122838857(il12rb1)
PPRL: 129376128(il12rb1)
CVG: 107099666(il12rb1)
CTUL: 119787640(il12rb1)
GMU: 124873440(il12rb1)
NFU: 107392624 107392799
KMR: 108234318(il12rb1)
ALIM: 106519187
NWH: 119430673(il12rb1)
AOCE: 111576546
MCEP: 125009665(il12rb1)
CSEM: 103395987
SSEN: 122780405(il12rb1)
HHIP: 117760717 117775659
HSP: 118119117 118120664
SMAU: 118318532(il12rb1)
LCF: 108881184
SDU: 111216416(il12rb1)
SLAL: 111669988(il12rb1)
XGL: 120790921(il12rb1)
HCQ: 109519017
SSCV: 125976286
SBIA: 133503665(il12rb1)
PEE: 133405983(il12rb1)
PTAO: 133480316(il12rb1)
BPEC: 110167972
MALB: 109966833
BSPL: 114854299(il12rb1)
SJO: 128362251(il12rb1)
SASA: 106573901 106613637
STRU: 115151680 115158105
OTW: 112250740 112252134
OMY: 110493709 110524147
OGO: 123991465 123996373
ONE: 115108183
OKI: 109888604 109902383
OKE: 118388286 118401463
SALP: 111952333 111975344
SNH: 120053559 120054425
CCLU: 121532744 121576868
ELS: 105026196
SFM: 108930531(il12rb1)
AANG: 118224923(il12rb1)
LOC: 107079633(il12rb1)
PSPA: 121300621
ARUT: 117428961(il12rb1)
LERI: 129711096
 » show all
Reference
PMID:8617302
  Authors
Wu CY, Warrier RR, Carvajal DM, Chua AO, Minetti LJ, Chizzonite R, Mongini PK, Stern AS, Gubler U, Presky DH, Gately MK
  Title
Biological function and distribution of human interleukin-12 receptor beta chain.
  Journal
Eur J Immunol 26:345-50 (1996)
DOI:10.1002/eji.1830260212
  Sequence
[hsa:3594]
Reference
PMID:7911493
  Authors
Chua AO, Chizzonite R, Desai BB, Truitt TP, Nunes P, Minetti LJ, Warrier RR, Presky DH, Levine JF, Gately MK, et al.
  Title
Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130.
  Journal
J Immunol 153:128-36 (1994)
  Sequence
[hsa:3594]
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