KEGG ORTHOLOGY: K05066

ORTHOLOGY: K05066

Entry

K05066                      KO

Symbol

CSF2RA, GMCSFR, CD116

Name

granulocyte-macrophage colony-stimulating factor receptor alpha

Pathway

map04060

Cytokine-cytokine receptor interaction

map04630

JAK-STAT signaling pathway

map04640

Hematopoietic cell lineage

map05200

Pathways in cancer

Disease

H01122

Congenital pulmonary alveolar proteinosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05066  CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05066  CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05066  CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05066  CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05066  CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
   04090 CD molecules
    K05066  CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
Cytokine receptors [BR:ko04050]
Interleukin receptor families
  IL3 receptor family
   K05066  CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
CD molecules [BR:ko04090]
Proteins
  K05066  CD116, CSF2RA; colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)

Genes

HSA:	1438(CSF2RA)

PTR:	746936(CSF2RA)

PON:	100452320 100452697

NLE:	100596513 100602399 100605652 115834049 115834378

HMH:	116484577(CSF2RA)

MCF:	102139775(CSF2RA)

MTHB:

126946850 126947138

MNI:	105478257(CSF2RA)

CSAB:

103247514(CSF2RA)

CATY:

105590318(CSF2RA)

TGE:	112615949(CSF2RA)

MLEU:

105554242(CSF2RA)

RRO:	104663344(CSF2RA)

RBB:

108524070

TFN:	117076099(CSF2RA)

PTEH:

113220732

CANG:

105513134

CJC:	100413917(CSF2RA)

SBQ:	101038788(CSF2RA)

CIMI:

108296380(CSF2RA)

MMUR:

105870809(CSF2RA) 105870818

LCAT:

123628075

PCOQ:

105819031(CSF2RA)

OGA:	100945167(CSF2RA)

MMU:	12982(Csf2ra)

MCAL:

110285238

MPAH:

110315436

RNO:	652957(Csf2ra)

MCOC:

ANU:

MUN:

CGE:

MAUA:

PROB:

127231950(Csf2ra)

PLEU:

MORG:

MFOT:

NGI:

HGL:

CCAN:

DORD:

DSP:

PLOP:

NCAR:

MMMA:

OCU:

OPI:	101531536(CSF2RA)

TUP:	102476450(CSF2RA)

GVR:	103586806(CSF2RA)

CFA:	100686341 609266(CSF2RA)

CLUD:

112651927 112651941

VVP:	112908951 112908959

VLG:	121482308(CSF2RA) 121483170

NPO:	129518409 129518893(CSF2RA)

AML:	100469756(CSF2RA) 105238364

UMR:	103666290(CSF2RA) 103666329

UAH:	113240792 113240793(CSF2RA)

UAR:	123802758(CSF2RA)

ELK:	111157114 111157141

LLV:

125092117

MPUF:

101672208(CSF2RA) 101683998

MNP:	132007280 132007396

MLK:	131821160 131821161(CSF2RA)

NVS:	122896429 122897340

ORO:	101383473(CSF2RA) 105757391

EJU:	114218066 114218068

ZCA:	113930157 113930172

MLX:	118026665(CSF2RA) 118026666

NSU:	110593303(CSF2RA)

LWW:	102730926 102749694

FCA:	101100621 102901718

PYU:

121020164

PCOO:

112871663(CSF2RA) 112871705

PBG:	122476983(CSF2RA) 122477816

PVIV:

125159257 125159270

LRUF:

124509309 124509310

PTG:	102966764(CSF2RA)

PPAD:

109256168 109256169

PUC:	125931442 125931443

AJU:	106982042 106982043

HHV:	120240549 120240562

BTA:	100336606(CSF2RA)

BOM:	102279567(CSF2RA)

BIU:

109568669

BBUB:

102408349(CSF2RA)

BBIS:

104998745(CSF2RA)

CHX:	102175201(CSF2RA)

OAS:

101115509

BTAX:

128070001(CSF2RA)

ODA:

120882426

CCAD:

122434354

MBEZ:

129564521(CSF2RA)

SSC:	100620339(CSF2RA)

CFR:	102511890(CSF2RA)

CBAI:

105079511

CDK:

105103092

VPC:	102540989(CSF2RA)

BACU:

103005794(CSF2RA)

BMUS:

118888678(CSF2RA)

LVE:	103083689(CSF2RA)

OOR:	101280976(CSF2RA)

DLE:	111168273(CSF2RA)

PCAD:

102987016(CSF2RA)

PSIU:

116746993(CSF2RA)

NASI:

112415228(CSF2RA)

ECB:

102148014

EPZ:

103545274

EAI:	106842472(IL3RA) 106842481(CSF2RA)

MYB:	102246112(CSF2RA) 106725951

MMYO:

118657306 118657314(CSF2RA)

EFUS:

103304958(CSF2RA) 129150026

MNA:	107543956 107543958(CSF2RA)

DRO:	112313318(CSF2RA)

SHON:

118974340(CSF2RA) 118974345

AJM:	119045499 119045760(CSF2RA)

PHAS:

123830036(CSF2RA)

MMF:	118636238 118636251(CSF2RA)

PPAM:

129079763 129079765

HAI:	109375576(CSF2RA)

RFQ:

117028565

PALE:

102878494

PGIG:

120596738(CSF2RA)

PVP:

105308006

RAY:	107512554 107512583

MJV:	108389768 108389965

TOD:

119246374

SETR:

126000645

LAV:	100664139(CSF2RA) 111749385

TMU:	101359572 111822152

MDO:	103094977(CSF2RA)

GAS:

123241728

SHR:	105749994(CSF2RA)

AFZ:

127553695

PCW:	110212746(CSF2RA)

OAA:	103171402 103171406

GGA:	101747500(GMSRAL) 418666(CSF2RA)

PCOC:

116230788 116230789

MGP:	104916148 104916413

CJO:	107306196 107306208

TPAI:

128071776

LMUT:

125688399

NMEL:

110405891 110405900 110405920

APLA:

101793135 101793812 101794111 119715550

ACYG:

106035717

CATA:

118245664 118245690

AFUL:

116485928 116495571

TGU:	101232863 101233002

LSR:	110479386 110479387 110479393

SCAN:

103812320 103812628

PMOA:

120510186 120510197

OTC:	121345333 121345341

PRUF:

121354083 121354085

GFR:	102034569 102038667 106631862

FAB:	101815564 101818275

OMA:	130254223 130254256

PHI:	102106350 102106539

PMAJ:

107201450 107201488

CCAE:

111945764 111945781 111945793

CCW:	104686016 104686017

CBRC:

103611769 103611794

ETL:	114066995 114066996

ZAB:	102061179 102062036

ACHL:

103798188 103798189

SVG:	106862599 106862937

MMEA:

130584081 130584084

HRT:	120748564 120748945

FPG:	101917011 101917188 106112119

FCH:	102057300 102057469 106631140

CLV:	102094408 102094409 102094583

EGZ:	104125118 104125128

NNI:	104009839 104009847

PCRI:

104037501 104037503

PLET:

104615897 104616026

EHS:	104507202 104510018

PCAO:

104040870 104041736

ACUN:

113476856 113480646 113480652

TALA:

PADL:

AFOR:

ACHC:

HALD:

HLE:	104839873 104839874

AGEN:

126053044 126053048

GCL:	127029346 127029545

CCRI:

104156959 104163345

CSTI:

104552286 104552394

CMAC:

104475029 104478448

MUI:	104539564 104539565

BREG:

104631414 104634556

FGA:

104079426

GSTE:

104252858 104254564

LDI:	104347957 104347958

MNB:	103780010 103780628

OHA:	104326378 104326400

NNT:	104403231 104403239

SHAB:

DPUB:

PGUU:

ACAR:

CPEA:

AVIT:

CVF:

RTD:	128904213 128912575

CUCA:

104063742 104063743

TEO:	104372567 104372568

BRHI:

104493856 104494129

AAM:	106490908 106490917

AROW:

112960568 112960570

NPD:	112944018 112944036

TGT:	104570669 104570670

DNE:	112992410 112992412

SCAM:

104138689 104138692

ASN:	102384353 102388771

AMJ:	102557808(CSF2RA) 102558040

CPOO:

109306132 109306133

GGN:	109303281 109303380

PSS:	102457838 102458090 106732867

CMY:

CCAY:

DCC:

CPIC:

TST:

CABI:

MRV:	120395898 120395922

ACS:	103278321(csf2ra)

ASAO:

PVT:

SUND:

PBI:

PMUR:

CTIG:

TSR:

PGUT:

APRI:

PTEX:

NSS:

VKO:

PMUA:

PRAF:

ZVI:

HCG:

GJA:

STOW:

EMC:

XLA:	108707672 108707981 108709067

XTR:	101731565 101732217 116408799

RTEM:

120927485 120927487 120928037

BBUF:

BGAR:

MUO:

GSH:

SASA:

OTW:

OMY:

CMK:

HOC:

Reference

PMID:2555171

Authors

Gearing DP, King JA, Gough NM, Nicola NA

Title

Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor.

Journal

EMBO J 8:3667-76 (1989)
DOI:10.1002/j.1460-2075.1989.tb08541.x

Sequence

[hsa:1438]

Reference

PMID:25923510

Authors

Son BK, Sawaki D, Tomida S, Fujita D, Aizawa K, Aoki H, Akishita M, Manabe I, Komuro I, Friedman SL, Nagai R, Suzuki T

Title

Granulocyte macrophage colony-stimulating factor is required for aortic dissection/intramural haematoma.

Journal

Nat Commun 6:6994 (2015)
DOI:10.1038/ncomms7994

LinkDB

DBGET integrated database retrieval system