KEGG ORTHOLOGY: K05111

ORTHOLOGY: K05111

Entry

K05111                      KO

Symbol

EPHB2, ERK, DRT

Name

Eph receptor B2 [EC:2.7.10.1]

Pathway

map04360

Axon guidance

Disease

H01235

Bleeding disorder platelet-type

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    K05111  EPHB2, ERK, DRT; Eph receptor B2
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05111  EPHB2, ERK, DRT; Eph receptor B2
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05111  EPHB2, ERK, DRT; Eph receptor B2
Protein kinases [BR:ko01001]
Receptor tyrosine kinases (RTK)
  EPH family [OT]
   K05111  EPHB2, ERK, DRT; Eph receptor B2

Other DBs

GO:

0005003

Genes

HSA:	2048(EPHB2)

PTR:	456613(EPHB2)

PPS:	100970403(EPHB2)

GGO:	101142789(EPHB2)

PON:	100432564(EPHB2)

NLE:	100605350(EPHB2)

HMH:	116813052(EPHB2)

MCC:	718570(EPHB2)

MCF:	102137932(EPHB2)

MTHB:

126954674

MNI:	105494409(EPHB2)

CSAB:

103225406(EPHB2)

CATY:

105595014(EPHB2)

PANU:

101014211(EPHB2)

TGE:	112607135(EPHB2)

MLEU:

105529435(EPHB2)

RRO:	104663228(EPHB2)

RBB:	108538455(EPHB2)

TFN:	117093152(EPHB2)

PTEH:

111547710(EPHB2)

CANG:

105514281(EPHB2)

CJC:	100405872(EPHB2)

SBQ:	101047173(EPHB2)

CIMI:

108308625(EPHB2)

MMUR:

105863535(EPHB2)

LCAT:

123634442(EPHB2)

PCOQ:

105815669(EPHB2)

OGA:	100950372(EPHB2)

MMU:	13844(Ephb2)

MCAL:

110292143(Ephb2)

MPAH:

110323536(Ephb2)

RNO:	313633(Ephb2)

MCOC:

116096871(Ephb2)

ANU:	117708498(Ephb2)

MUN:	110545398(Ephb2)

CGE:	100766993(Ephb2)

MAUA:

101824816(Ephb2)

PROB:

127213265(Ephb2)

PLEU:

114697213(Ephb2)

MORG:

121447920(Ephb2)

MFOT:

126509719

AAMP:

119816581(Ephb2)

NGI:	103746401(Ephb2)

HGL:	101705033(Ephb2)

CPOC:

100724302(Ephb2)

CCAN:

109681851(Ephb2) 109694917

DORD:

105998124(Ephb2)

DSP:	122115218(Ephb2)

PLOP:

125354697(Ephb2)

NCAR:

124991090

MMMA:

107141560(Ephb2)

OCU:

100359223

OPI:	101531279(EPHB2)

TUP:	102484138(EPHB2)

GVR:	103590532(EPHB2)

CFA:	487380(EPHB2)

CLUD:

112659977(EPHB2)

VVP:	112930136(EPHB2)

VLG:	121496499(EPHB2)

NPO:	129513674(EPHB2)

AML:	100469085(EPHB2)

UMR:	103666792(EPHB2)

UAH:	113268535(EPHB2)

UAR:	123782379(EPHB2)

ELK:

111154676

LLV:

125098673

MPUF:

101683889(EPHB2)

MNP:	132001749(EPHB2)

MLK:	131809470(EPHB2)

NVS:	122899551(EPHB2)

ORO:	101372345(EPHB2)

EJU:	114199056(EPHB2)

ZCA:	113915454(EPHB2)

MLX:	118019906(EPHB2)

NSU:	110574744(EPHB2)

LWW:	102743924(EPHB2)

FCA:	101095030(EPHB2)

PYU:	121022888(EPHB2)

PCOO:

112862224(EPHB2)

PBG:	122480076(EPHB2)

PVIV:

125173948(EPHB2)

LRUF:

124514391

PTG:	102971000(EPHB2)

PPAD:

109274284(EPHB2)

PUC:

125912987

AJU:

106977651

HHV:	120232792(EPHB2)

BTA:	535137(EPHB2)

BOM:	102264515(EPHB2)

BIU:	109574025(EPHB2)

BBUB:

102396059(EPHB2)

BBIS:

104981237

CHX:	102186352(EPHB2)

OAS:	101122928(EPHB2)

BTAX:

128043392(EPHB2)

ODA:	120855023(EPHB2)

CCAD:

122426116(EPHB2)

MBEZ:

129538191(EPHB2)

SSC:	100519549(EPHB2)

CFR:	102517534(EPHB2)

CBAI:

105070867(EPHB2)

CDK:	105088876(EPHB2)

VPC:	102532557(EPHB2)

BACU:

103011913(EPHB2)

BMUS:

118886750(EPHB2)

LVE:	103085807(EPHB2)

OOR:	101272607(EPHB2)

DLE:	111163325(EPHB2)

PCAD:

102997037

PSIU:

116742471(EPHB2)

NASI:

112414292(EPHB2)

ECB:	100071661(EPHB2)

EPZ:	103551309(EPHB2)

EAI:	106839996(EPHB2)

MYB:	102261811(EPHB2)

MYD:	102755723(EPHB2)

MMYO:

118676995(EPHB2)

MLF:	102430753(EPHB2)

PKL:

118722479

EFUS:

103291964(EPHB2)

MNA:	107538412(EPHB2)

DRO:	112299201(EPHB2)

SHON:

118977832(EPHB2)

AJM:	119042248(EPHB2)

PDIC:

114496590(EPHB2)

PHAS:

123831697(EPHB2)

MMF:	118626116(EPHB2)

PPAM:

129068977(EPHB2)

HAI:	109375894(EPHB2)

RFQ:	117027326(EPHB2)

PALE:

102886872(EPHB2)

PGIG:

120596208(EPHB2)

PVP:	105290663(EPHB2)

RAY:	107513064(EPHB2)

MJV:	108407309(EPHB2)

TOD:	119236213(EPHB2)

SARA:

101541851(EPHB2)

SETR:

126011018(EPHB2)

LAV:	100663630(EPHB2)

TMU:

101360928

ETF:	101645733(EPHB2)

DNM:	101437781(EPHB2)

MDO:	100025347(EPHB2)

GAS:	123243137(EPHB2)

SHR:	100923681(EPHB2)

AFZ:

127555730

PCW:	110206040(EPHB2)

OAA:	100681631(EPHB2)

GGA:	396513(EPHB2)

PCOC:

116238360(EPHB2)

MGP:	100544000(EPHB2)

CJO:	107323522(EPHB2)

TPAI:

128084936(EPHB2)

LMUT:

125703306(EPHB2)

NMEL:

110408558(EPHB2)

APLA:

101802929(EPHB2)

ACYG:

106040142(EPHB2)

CATA:

118253335(EPHB2)

AFUL:

116497607(EPHB2)

TGU:	100218346(EPHB2)

LSR:	110472243(EPHB2)

SCAN:

103824166(EPHB2)

PMOA:

120498984(EPHB2)

OTC:	121333068(EPHB2)

PRUF:

121351357(EPHB2)

GFR:	102035359(EPHB2)

FAB:	101807464(EPHB2)

OMA:	130261781(EPHB2)

PHI:	102105076(EPHB2)

PMAJ:

107213703(EPHB2)

CCAE:

111938496(EPHB2)

CCW:	104697547(EPHB2)

CBRC:

103616182(EPHB2)

ETL:	114070036 114071741

ZAB:	102066336(EPHB2)

ACHL:

103801885

SVG:	106856406(EPHB2)

MMEA:

130582494(EPHB2)

HRT:	120762226(EPHB2)

FPG:	101914058(EPHB2)

FCH:	102056206(EPHB2)

CLV:	102098920(EPHB2)

EGZ:	104131868(EPHB2)

NNI:	104011206(EPHB2)

PCRI:

104029025(EPHB2)

EHS:

104507302

PCAO:

104042510(EPHB2)

ACUN:

113487746(EPHB2)

TALA:

104365046(EPHB2)

PADL:

103925400(EPHB2)

AFOR:

103907006(EPHB2)

ACHC:

115342812(EPHB2)

HALD:

104317185

HLE:	104837802(EPHB2)

AGEN:

126041658

GCL:

127024861

CCRI:

104162768(EPHB2)

CSTI:

CMAC:

MUI:

BREG:

GSTE:

104260523(EPHB2)

LDI:

104346239

OHA:

104330014

SHAB:

115617348(EPHB2)

DPUB:

104297488(EPHB2)

PGUU:

104464049(EPHB2)

CPEA:

104387757(EPHB2)

AVIT:

104275958(EPHB2)

CVF:	104290700(EPHB2)

RTD:	128918388(EPHB2)

CUCA:

104060764(EPHB2)

TEO:

104377032

BRHI:

104492357(EPHB2)

AAM:	106496015 106496191

AROW:

112966854(EPHB2)

NPD:	112957428(EPHB2)

TGT:	104566947(EPHB2)

DNE:	112988461(EPHB2)

SCAM:

104153647(EPHB2)

ASN:	102386589(EPHB2)

AMJ:	102560514(EPHB2)

CPOO:

109314279(EPHB2)

GGN:	109293886(EPHB2)

PSS:	102446247(EPHB2)

CMY:	102934676(EPHB2)

CCAY:

125624323(EPHB2)

DCC:	119844996(EPHB2)

CPIC:

101943142(EPHB2)

TST:	117867869(EPHB2)

CABI:

116814948(EPHB4) 116829028(EPHB2)

MRV:	120387769(EPHB2)

ACS:	100558048 100558640

PVT:	110089368(EPHB2)

SUND:

121936919(EPHB2)

PBI:	103052079 103067863

PMUR:

107284658(EPHB2)

CTIG:

120319115(EPHB2)

TSR:

106543351

PGUT:

117656623

APRI:

131187136(EPHB2)

PTEX:

113450789(EPHB2)

NSS:

113427328

VKO:	123034743(EPHB2)

PMUA:

114602963(EPHB2)

PRAF:

128419644(EPHB2)

ZVI:	118087339(EPHB2)

HCG:	128338495(EPHB2)

GJA:	107114922(EPHB2)

STOW:

125445709(EPHB2)

EMC:	129344427(EPHB2)

XLA:	108697272(ephb2.S) 108705066

XTR:

116410852

NPR:	108802636 108803651

RTEM:

120916172

BBUF:

120995015(EPHB2)

BGAR:

122929020(EPHB2)

MUO:	115482527(EPHB2)

GSH:	117349185(EPHB2)

DRE:	554232(ephb2b) 562176(ephb2a)

SRX:	107712652 107727812 107737672 107749421

SANH:

107685632 107687404 107691322 107703068

SGH:	107555673 107568432 107591131 107593373

CCAR:

109072068 109072073 109112765

CAUA:

113068386 113068880 113080796 113095944 113111097

CGIB:

127945189 127968250 128012110 128022247

PTET:

122329107(ephb2a) 122354350(ephb2b)

LROH:

127154750(ephb2a) 127172829(ephb2b)

OMC:	131532322(ephb2a) 131549296(ephb2b)

PPRM:

120463782(ephb2a) 120480623(ephb2b)

RKG:	130085562(ephb2b) 130102150(ephb2a)

MAMB:

125257167(ephb2b) 125260001(ephb2a)

CIDE:

127505132 127522613

MASI:

127419469 127419681 127426179 127427574

TROS:

130571127(ephb2b) 130572007(ephb2a)

TDW:	130409254(ephb2a) 130410045(ephb2b)

MANU:

129427172(ephb2b) 129430674(ephb2a)

IPU:	108255231(ephb2b) 108275960(ephb2a)

IFU:	128619116(ephb2a) 128625126(ephb2b)

PHYP:

113530787 113537927

SMEO:

124402151(ephb2b)

TFD:	113655161(ephb2b) 113658069(ephb2a)

TVC:	132837981(ephb2b) 132862079(ephb2a)

AMEX:

103021578 103031596(ephb2)

CMAO:

118799468(ephb2b) 118822625(ephb2a)

EEE:	113569980 113586324

CHAR:

105894254(ephb2a) 105912180(ephb2b)

TRU:	101065603 101069940

TFS:	130523903(ephb2b) 130529435

TNG:	GSTEN00012392G001 GSTEN00022950G001

LCO:	104917933 104932800

NCC:

104954670

TBEN:

117481478(ephb2a) 117489554(ephb2b)

CGOB:

115007762 115019705(ephb2)

PGEO:

117446660(ephb2b) 117449476(ephb2a)

GACU:

117539464(ephb2b) 117559255

EMAC:

134863990(ephb2a) 134883045(ephb2b)

ELY:	117256844(ephb2b) 117258812

EFO:	125891528 125897455(ephb2b)

PLEP:

121946708 121959853(ephb2b)

SLUC:

116050878 116051519(ephb2b)

ECRA:

117943496(ephb2b) 117947113

ESP:	116687853 116691960

PFLV:

114553921(ephb2) 114558305

GAT:	120829196(ephb2a) 120835681(ephb2b)

PPUG:

119223707 119229959(ephb2b)

AFB:	129100203(ephb2a) 129106385(ephb2b)

CLUM:

117730583(ephb2b)

PSWI:

130208246(ephb2b)

MSAM:

119886440(ephb2b) 119904994

SCHU:

122861759(ephb2b) 122883712(ephb2a)

CUD:	121506881(ephb2b) 121517588

ALAT:

119021184(ephb2b) 119022773(ephb2a)

MZE:	101473498 101487531

ONL:	100706982 100712288

OAU:	116315081(ephb2b) 116323399

OLA:	101156311 101165974

OML:	112140020 112144920(ephb2b)

CSAI:

133448428(ephb2b) 133457563

XMA:	102223554 102224162(ephb2)

XCO:	114135512(ephb2) 114141081

XHE:	116710449(ephb2) 116722272

PRET:

103464764(ephb2) 103468061

PFOR:

103134655(ephb2) 103153474

PLAI:

106936645 106951993

PMEI:

106925031 106933381

GAF:	122831993 122833797(ephb2b)

PPRL:

129352956 129372737(ephb2b)

CVG:	107081144 107085152(ephb2) 107090696

CTUL:

119773562 119799455(ephb2a)

GMU:	124856645(ephb2b) 124876437

NFU:	107384891(ephb2)

KMR:	108231611(ephb2b)

ALIM:

106518340(ephb2)

NWH:	119412063(epha8) 119412070

AOCE:

111568257 111576077

MCEP:

125006614(ephb2b) 125024046

CSEM:

103384836 103386470

POV:	109635520(ephb2) 109643917

SSEN:

122767978(ephb2b) 122777564

HHIP:

117761418(ephb2b) 117764397

HSP:	118104863(ephb2b) 118111257(ephb2a)

SMAU:

118309656(ephb2b) 118317354

LCF:	108900511(ephb2a) 108902521(ephb2b)

SDU:	111218961 111233535(ephb2)

SLAL:

111660683(ephb2) 111670708

XGL:	120782937(ephb2b) 120803938

HCQ:	109508269(ephb2)

SSCV:

125977161

SBIA:

133507253(ephb2b)

PEE:	133408362(ephb2b)

PTAO:

133483701(ephb2b)

BPEC:

110154601 110170491

MALB:

109957335(ephb2)

BSPL:

114855275(ephb2b) 114858806

SJO:	128355053(ephb2b) 128356869(ephb2a)

SASA:

106565894 106566817 106572237 106582986

STRU:

115150722 115166282 115168268 115207717

OTW:	112215879 112218521 112222067 112254477(ephb2b)

OMY:	110492289 110494446 110528000 110532127

OGO:	124003055 124031384 124031805 124045775

ONE:	115102212 115132009 115138814 115143271

OKI:	109869324 109891046 109896637 109907866

OKE:	118359731 118361278 118388477 118400208

SALP:

111966316 111967748 111969988 111976998

SNH:	120059427 120059432 120060730 120065126(ephb2b)

CCLU:

121538193 121545520 121575371 121577725

ELS:	105013901 105017235

SFM:	108918489(ephb2) 108933508

PKI:	111852052 111859064

AANG:

118208528 118211777

LOC:	102697394(ephb2)

PSPA:

121329132 121329232

ARUT:

117425646 117432285

PSEX:

120530911

LCM:	102358195(EPHA10)

CMK:

RTP:

CPLA:

HOC:

LERI:

PMRN:

LRJ:	133351079 133352489

SCLV:

120327739 120328310

LPIC:

129276821

AJC:	117101814 117101848

SKO:

100313591

PVUL:

126826683

CVN:	111134042 111134043

CANU:

OED:

MCAF:

NVE:

EPA:	110240749 110240758 110240759 110240760 110251416 110251576 110251578 110252100 110252150 110252151

ADF:	107348281 107353959 107353963 107356685 107358823

AMIL:

114947107 114949354 114959995 114967569 114972000

PDAM:

113674895

SPIS:

111341142

DGT:	114518513 114518514

HSY:

130641896

AQU:

100635378

» show all

Reference

PMID:8134103

Authors

Henkemeyer M, Marengere LE, McGlade J, Olivier JP, Conlon RA, Holmyard DP, Letwin K, Pawson T

Title

Immunolocalization of the Nuk receptor tyrosine kinase suggests roles in segmental patterning of the brain and axonogenesis.

Journal

Oncogene 9:1001-14 (1994)

Sequence

[mmu:13844]

Reference

PMID:21078817

Authors

Pitulescu ME, Adams RH

Title

Eph/ephrin molecules--a hub for signaling and endocytosis.

Journal

Genes Dev 24:2480-92 (2010)
DOI:10.1101/gad.1973910

LinkDB

DBGET integrated database retrieval system