KEGG ORTHOLOGY: K05132

ORTHOLOGY: K05132

Entry

K05132                      KO

Symbol

IFNGR1, CD119

Name

interferon gamma receptor 1

Pathway

map04060

Cytokine-cytokine receptor interaction

map04066

HIF-1 signaling pathway

map04217

Necroptosis

map04380

Osteoclast differentiation

map04630

JAK-STAT signaling pathway

map04650

Natural killer cell mediated cytotoxicity

map04658

Th1 and Th2 cell differentiation

map04659

Th17 cell differentiation

map05140

Leishmaniasis

map05142

Chagas disease

map05145

Toxoplasmosis

map05152

Tuberculosis

map05164

Influenza A

map05167

Kaposi sarcoma-associated herpesvirus infection

map05168

Herpes simplex virus 1 infection

map05200

Pathways in cancer

map05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

map05321

Inflammatory bowel disease

Disease

H00089

IFN-gamma/IL-12 axis

H00342

Tuberculosis

H00412

Hepatitis B

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   04066 HIF-1 signaling pathway
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05132  IFNGR1, CD119; interferon gamma receptor 1
09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K05132  IFNGR1, CD119; interferon gamma receptor 1
09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   04658 Th1 and Th2 cell differentiation
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   04659 Th17 cell differentiation
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05132  IFNGR1, CD119; interferon gamma receptor 1
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  09172 Infectious disease: viral
   05164 Influenza A
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05168 Herpes simplex virus 1 infection
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05140 Leishmaniasis
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05142 Chagas disease
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05132  IFNGR1, CD119; interferon gamma receptor 1
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   04090 CD molecules
    K05132  IFNGR1, CD119; interferon gamma receptor 1
Cytokine receptors [BR:ko04050]
Interleukin receptor families
  IFN receptor family
   K05132  IFNGR1, CD119; interferon gamma receptor 1
CD molecules [BR:ko04090]
Proteins
  K05132  CD119, IFNGR1; interferon gamma receptor 1

Other DBs

GO:

0004906

Genes

HSA:	3459(IFNGR1)

PTR:	747276(IFNGR1)

PPS:	100994342(IFNGR1)

GGO:	101150227(IFNGR1)

PON:	100171593(IFNGR1)

NLE:	100598615(IFNGR1)

HMH:	116472865(IFNGR1)

MCC:	100423877(IFNGR1)

MCF:	101866179(IFNGR1)

MTHB:

126952034

MNI:	105465687(IFNGR1)

CSAB:

103240303(IFNGR1)

CATY:

105600393(IFNGR1)

PANU:

101000704(IFNGR1)

TGE:	112622388(IFNGR1)

MLEU:

105538544(IFNGR1)

RRO:	104675021(IFNGR1)

RBB:	108522967(IFNGR1)

TFN:	117097473(IFNGR1)

PTEH:

111525525(IFNGR1)

CANG:

105526167(IFNGR1)

CJC:	100386516(IFNGR1)

SBQ:	101054160(IFNGR1)

CIMI:

108305706(IFNGR1)

CSYR:

103256032(IFNGR1)

MMUR:

105860595(IFNGR1)

LCAT:

123633306(IFNGR1)

PCOQ:

105827142(IFNGR1)

OGA:	100960904(IFNGR1)

MMU:	15979(Ifngr1)

MCAL:

110303040(Ifngr1)

MPAH:

110338217(Ifngr1)

RNO:	116465(Ifngr1)

MCOC:

116097807(Ifngr1)

ANU:	117701112(Ifngr1)

MUN:	110557641(Ifngr1)

CGE:	100772793(Ifngr1)

MAUA:

101827289(Ifngr1)

PROB:

127215047(Ifngr1)

PLEU:

114686090

MORG:

121449681(Ifngr1)

MFOT:

126511927

AAMP:

119821190(Ifngr1)

NGI:	103724895(Ifngr1)

HGL:	101709169(Ifngr1)

CPOC:

100724091(Ifngr1)

CCAN:

109697033(Ifngr1)

DORD:

105993592(Ifngr1)

DSP:	122118073(Ifngr1)

PLOP:

125357332(Ifngr1)

NCAR:

124988784

MMMA:

107155664(Ifngr1)

OCU:

100341787

OPI:	101531101(IFNGR1)

TUP:	102475588(IFNGR1)

GVR:	103591435(IFNGR1)

CFA:	100856077(IFNGR1)

CLUD:

112644179(IFNGR1)

VVP:	112919471(IFNGR1)

VLG:	121485259(IFNGR1)

NPO:	129509273(IFNGR1)

AML:	100473768(IFNGR1)

UMR:	103663370(IFNGR1)

UAH:	113259485(IFNGR1)

UAR:	123803346(IFNGR1)

ELK:

111147686

LLV:

125102526

MPUF:

101690491(IFNGR1)

MNP:	132018188(IFNGR1)

MLK:	131833755(IFNGR1)

NVS:	122906241(IFNGR1)

ORO:	101375882(IFNGR1)

EJU:	114222763(IFNGR1)

ZCA:	113927325(IFNGR1)

MLX:	118000839(IFNGR1)

NSU:	110583311(IFNGR1)

LWW:	102725692(IFNGR1)

FCA:	101086811(IFNGR1)

PYU:	121013404(IFNGR1)

PCOO:

112861963(IFNGR1)

PBG:	122490015(IFNGR1)

PVIV:

125166166(IFNGR1)

LRUF:

124527922

PTG:	102952498(IFNGR1)

PPAD:

109249871(IFNGR1)

PUC:

125938948

AJU:

106985768

HHV:	120239366(IFNGR1)

BTA:	508619(IFNGR1)

BOM:	102275527(IFNGR1)

BIU:	109563984(IFNGR1)

BBUB:

102410135(IFNGR1)

BBIS:

104991667(IFNGR1)

CHX:	102182698(IFNGR1)

OAS:	101112907(IFNGR1)

BTAX:

128053263(IFNGR1)

ODA:	120863075(IFNGR1)

CCAD:

122433969(IFNGR1)

MBEZ:

129560886(IFNGR1)

SSC:	100152238(IFNGR1)

CFR:	102522759(IFNGR1)

CBAI:

105077267(IFNGR1)

CDK:	105092040(IFNGR1)

VPC:	102545778(IFNGR1)

BACU:

103000886(IFNGR1)

BMUS:

118905127(IFNGR1)

LVE:	103082113(IFNGR1)

OOR:	101276054(IFNGR1)

DLE:	111166198(IFNGR1)

PCAD:

102977921(IFNGR1)

PSIU:

116763420(IFNGR1)

NASI:

112409086(IFNGR1)

ECB:	100073195(IFNGR1)

EPZ:	103549045(IFNGR1)

EAI:	106837196(IFNGR1)

MYB:	102258073(IFNGR1)

MYD:	102761556(IFNGR1)

MMYO:

118659706(IFNGR1)

MLF:	102440031(IFNGR1)

PKL:	118705949(IFNGR1)

EFUS:

103285013(IFNGR1)

MNA:	107530983(IFNGR1)

DRO:	112297082(IFNGR1)

SHON:

118986670(IFNGR1)

AJM:	119051850(IFNGR1)

PDIC:

114495155(IFNGR1)

PHAS:

123821790(IFNGR1)

MMF:	118621177(IFNGR1)

PPAM:

129067802(IFNGR1)

HAI:	109376141 109385640(IFNGR1)

RFQ:	117020615(IFNGR1)

PALE:

102888010(IFNGR1)

PGIG:

120615773(IFNGR1)

PVP:	105289469(IFNGR1)

RAY:	107521298(IFNGR1)

MJV:	108410304(IFNGR1)

TOD:	119252911(IFNGR1)

SARA:

101546718(IFNGR1)

SETR:

126031410(IFNGR1)

LAV:	100665172(IFNGR1)

TMU:

101345582

ETF:	101642657(IFNGR1)

DNM:	101416634(IFNGR1)

MDO:	100031565(IFNGR1)

GAS:	123247976(IFNGR1)

SHR:	111720994(IFNGR1)

AFZ:

127562254

PCW:	110208928(IFNGR1)

OAA:	100078574(IFNGR1)

GGA:	421685(IFNGR1)

PCOC:

116240614(IFNGR1)

MGP:	100550637(IFNGR1)

CJO:	107311677(IFNGR1)

TPAI:

128076749(IFNGR1)

LMUT:

125688697(IFNGR1)

NMEL:

110395971(IFNGR1)

APLA:

101799854(IFNGR1)

ACYG:

106032518(IFNGR1)

CATA:

118244196(IFNGR1)

AFUL:

116487277(IFNGR1)

TGU:	100222262(IFNGR1)

LSR:	110483306(IFNGR1)

SCAN:

103818469(IFNGR1)

PMOA:

120501163(IFNGR1)

OTC:	121346151(IFNGR1)

PRUF:

121354824(IFNGR1)

GFR:	102034996(IFNGR1)

FAB:	101813223(IFNGR1)

OMA:	130250883(IFNGR1)

PHI:	102104751(IFNGR1)

PMAJ:

107202224(IFNGR1)

CCAE:

111926795(IFNGR1)

CCW:	104689508(IFNGR1)

CBRC:

103617674(IFNGR1)

ETL:	114059495(IFNGR1)

ZAB:	102062242(IFNGR1)

ACHL:

103810491(IFNGR1)

SVG:	106854891(IFNGR1)

MMEA:

130576340(IFNGR1)

HRT:	120750324(IFNGR1)

FPG:	101911079(IFNGR1)

FCH:	102048414(IFNGR1)

CLV:	102085405(IFNGR1)

EGZ:	104131138(IFNGR1)

NNI:	104008886(IFNGR1)

PCRI:

104032523(IFNGR1)

PLET:

104626004(IFNGR1)

EHS:	104508703(IFNGR1)

PCAO:

104042236(IFNGR1)

ACUN:

113478368(IFNGR1)

TALA:

104361805(IFNGR1)

PADL:

103912749(IFNGR1)

AFOR:

103900802(IFNGR1)

ACHC:

115344821(IFNGR1)

HALD:

104317287(IFNGR1)

HLE:	104836420(IFNGR1)

AGEN:

126038997

GCL:

127014207

CCRI:

104159718

CSTI:

104558517(IFNGR1)

CMAC:

104475444(IFNGR1)

MUI:	104535806(IFNGR1)

BREG:

104634347(IFNGR1)

FGA:	104075141(IFNGR1)

GSTE:

104264539(IFNGR1)

LDI:	104351985(IFNGR1)

MNB:	103773034(IFNGR1)

OHA:	104327112(IFNGR1)

NNT:	104402682(IFNGR1)

SHAB:

115609451(IFNGR1)

DPUB:

104310006(IFNGR1)

ACAR:

104528182(IFNGR1)

CPEA:

104392364(IFNGR1)

CVF:	104284052(IFNGR1)

RTD:	128906870(IFNGR1)

CUCA:

104056256(IFNGR1)

TEO:	104375898(IFNGR1)

BRHI:

104495059(IFNGR1)

AAM:	106497894(IFNGR1)

AROW:

112971129(IFNGR1)

NPD:	112954920(IFNGR1)

TGT:	104576015(IFNGR1)

DNE:	112995205(IFNGR1)

SCAM:

104153174(IFNGR1)

ASN:	102374995(IFNGR1)

AMJ:	102566228(IFNGR1)

CPOO:

109320188(IFNGR1)

GGN:	109304488(IFNGR1)

PSS:	102448524(IFNGR1)

CMY:	102936486(IFNGR1)

CCAY:

125634132(IFNGR1)

DCC:	119853577(IFNGR1)

CPIC:

101945033(IFNGR1)

TST:	117874898(IFNGR1)

CABI:

116818785(IFNGR1)

MRV:	120400602(IFNGR1)

ACS:	103279436(ifngr1)

ASAO:

132760997(IFNGR1)

PVT:

110071491

SUND:

121919247

PBI:	103056914(IFNGR1)

PMUR:

107294497(IFNGR1)

CTIG:

120298684(IFNGR1)

TSR:	106554510(IFNGR1)

PGUT:

117666301(IFNGR1)

APRI:

131192114(IFNGR1)

PTEX:

113439621(IFNGR1)

NSS:	113411209(IFNGR1)

VKO:	123020307(IFNGR1)

PMUA:

114594178(IFNGR1)

PRAF:

128410577(IFNGR1)

ZVI:	118082067(IFNGR1)

HCG:	128342052(IFNGR1)

GJA:	107121392(IFNGR1)

STOW:

125429051(IFNGR1)

EMC:	129323728(IFNGR1)

XLA:

108717881

XTR:	780275(ifngr1)

RTEM:

120937355(IFNGR1)

BBUF:

120998527(IFNGR1)

BGAR:

122935766(IFNGR1)

MUO:	115466929(IFNGR1)

GSH:	117358031(IFNGR1)

DRE:	100329124(ifngr1l) 571368(ifngr1) 794493(gdf10b)

SRX:	107712350 107751166(ifngr1) 107751202

SANH:

107681035 107681036 107699164 107699165 107703709

SGH:	107561966 107561977 107561978 107597708

CCAR:

109070061(ifngr1) 109111911 109111913

CAUA:

113057375 113057376 113113080

CGIB:

127969651 127969652

PTET:

122326585(ifngr1) 122335479(ifngr1l) 122341232

LROH:

127174797 127174798(ifngr1l) 127174799

OMC:	131549168(ifngr1) 131550592 131551719 131552444

PPRM:

120488767(ifngr1) 120492285(ifngr1l)

RKG:	130070064(ifngr1) 130095215(ifngr1l)

MAMB:

125271771(ifngr1) 125277488

CIDE:

127515616 127524637

MASI:

127411747 127413624

TROS:

130553461(ifngr1) 130559186(ifngr1l)

TDW:	130410056(ifngr1) 130431842(ifngr1l)

MANU:

129416556(ifngr1l) 129435514 129443990(ifngr1)

IPU:	108258543(ifngr1) 108263559(ifngr1l)

IFU:	128601977(ifngr1) 128605280(ifngr1l)

PHYP:

113537513 113542090(ifngr1)

SMEO:

124377879(ifngr1) 124398203(ifngr1l)

TFD:	113655269(ifngr1l) 113663656(ifngr1)

TVC:	132839225(ifngr1) 132847011(ifngr1l)

AMEX:

103034782 103041106

CMAO:

118798312(ifngr1) 118810127(ifngr1l)

EEE:	113579645 113585524(ifngr1)

TRU:	105416329(ifngr1l) 105418770(ifngr1)

TFS:	130527489(ifngr1) 130533498(ifngr1l)

TNG:	GSTEN00011958G001

LCO:	104918512 104931539(ifngr1l)

TBEN:

117481854(ifngr1) 117499885(ifngr1l)

CGOB:

115019913

PGEO:

117450507(ifngr1) 117459622(ifngr1l)

GACU:

117555255(ifngr1) 117560846(ifngr1l)

EMAC:

134858988(ifngr1l) 134864299(ifngr1)

ELY:	117248396(ifngr1l) 117255556(ifngr1)

EFO:	125885472(ifngr1) 125903411(ifngr1l)

PLEP:

121941579(ifngr1) 121954432(ifngr1l)

SLUC:

116052185(ifngr1) 116056340(ifngr1l)

ECRA:

117952104(ifngr1) 117960046(ifngr1l)

ESP:	116689763 116705106(ifngr1)

PFLV:

114545237 114571908

GAT:	120820620(ifngr1l) 120825540(ifngr1)

PPUG:

119214211(ifngr1l) 119217644

AFB:	129092158(ifngr1l)

CLUM:

117732891(ifngr1) 117744159(ifngr1l)

PSWI:

130189545 130207324(ifngr1l)

MSAM:

119898250 119898260 119916915(ifngr1l)

SCHU:

122873151(ifngr1) 122884363(ifngr1l)

CUD:	121509097(ifngr1) 121510630(ifngr1l)

ALAT:

119019458(ifngr1) 119033918(ifngr1l)

MZE:	101468425(ifngr1)

ONL:	100690512(ifngr1l) 102081538(ifngr1)

OAU:	116321481(ifngr1) 116325733(ifngr1l)

OLA:	101172790 105357941

OML:	112156998 112162119(ifngr1l)

CSAI:

133446988(ifngr1) 133463865(ifngr1l)

XMA:	102216665 102225433

XCO:	114137918(ifngr1) 114144226

XHE:	116713191(ifngr1) 116720158

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122830274(ifngr1) 122842095(ifngr1l)

PPRL:

129359771(ifngr1l)

CVG:

107098124

CTUL:

119776758 119790554(ifngr1l)

GMU:	124859218(ifngr1l) 124868513(ifngr1)

NFU:	107375815 107397193

KMR:	108246304(ifngr1)

ALIM:

106531287

NWH:	119418673(ifngr1l)

AOCE:

111567671 111583941

MCEP:

125004137

CSEM:

103383887

POV:	109630900 109641612

SSEN:

122762639(ifngr1) 122781399(ifngr1l)

HHIP:

117764742(ifngr1) 117775149(ifngr1l)

HSP:	118099060(ifngr1) 118119530(ifngr1l)

SMAU:

118283525(ifngr1l) 118312746(ifngr1)

LCF:	108882483 108897373(ifngr1l)

SDU:	111235225(ifngr1) 111238244

SLAL:

111645304(ifngr1) 111659455

XGL:	120796346(ifngr1l) 120800137(ifngr1)

HCQ:

109512620

SSCV:

125969372

SBIA:

133506130(ifngr1) 133509811(ifngr1l)

PEE:	133404647(ifngr1) 133409988

PTAO:

133476600(ifngr1) 133486149

BPEC:

110157034 110172795

MALB:

109974821

BSPL:

114841829(ifngr1l)

SJO:	128373078(ifngr1l) 128380296(ifngr1)

SASA:

106564725 106587463 106589674(ifngr1) 106589675

STRU:

115201488 115201489 115208721

OTW:	112224548 112224549 112265249(ifngr1)

OMY:	100136117(ifngr1l) 110485858 110493590(ifngr1) 110499283

OGO:	124015674 124040270

ONE:	115142492(ifngr1) 115142493 115144330 115144331

OKI:	109865855 109870054(ifngr1l2) 109870057(ifngr1l1) 109888906(ifngr1) 116355433

OKE:	118364870(ifngr1) 118402835

SALP:

111968021 111982476

SNH:	120029797 120029876 120066393

CCLU:

121547629 121547632

ELS:	105021221(ifngr1l) 105021504

SFM:	108918633 108932840(ifngr1l)

PKI:	111837605(ifngr1) 111850737

AANG:

118218015 118218069(ifngr1)

LOC:

PSPA:

ARUT:

PSEX:

LCM:	102362892(IFNGR1)

CMK:

103178320

HOC:	132805510(ifngr1l)

» show all

Reference

PMID:2971451

Authors

Aguet M, Dembic Z, Merlin G

Title

Molecular cloning and expression of the human interferon-gamma receptor.

Journal

Cell 55:273-80 (1988)
DOI:10.1016/0092-8674(88)90050-5

Sequence

[hsa:3459]

Reference

PMID:15123776

Authors

Donnelly RP, Sheikh F, Kotenko SV, Dickensheets H

Title

The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain.

Journal

J Leukoc Biol 76:314-21 (2004)
DOI:10.1189/jlb.0204117

LinkDB

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