KEGG ORTHOLOGY: K05146

ORTHOLOGY: K05146

Entry

K05146                      KO

Symbol

TNFRSF9, CD137

Name

tumor necrosis factor receptor superfamily member 9

Pathway

map04060

Cytokine-cytokine receptor interaction

Disease

H01725

Primary immunodeficiency disease

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05146  TNFRSF9, CD137; tumor necrosis factor receptor superfamily member 9
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05146  TNFRSF9, CD137; tumor necrosis factor receptor superfamily member 9
   04090 CD molecules
    K05146  TNFRSF9, CD137; tumor necrosis factor receptor superfamily member 9
Cytokine receptors [BR:ko04050]
Tumor necrosis factor receptors
  TNF receptor superfamily
   K05146  TNFRSF9, CD137; tumor necrosis factor receptor superfamily member 9
CD molecules [BR:ko04090]
Proteins
  K05146  CD137, TNFRSF9; tumor necrosis factor receptor superfamily, member 9

Other DBs

GO:

0005031

Genes

HSA:	3604(TNFRSF9)

PTR:	746029(TNFRSF9)

PPS:	100970821(TNFRSF9)

GGO:	101133085(TNFRSF9)

PON:	100445262(TNFRSF9)

NLE:	100589207(TNFRSF9)

HMH:	116813893(TNFRSF9)

MCC:	708281(TNFRSF9)

MCF:	102127961(TNFRSF9)

MTHB:

126953487

MNI:	105479294(TNFRSF9)

CSAB:

103225663(TNFRSF9)

CATY:

105580916(TNFRSF9)

PANU:

100196937(TNFRSF9)

TGE:	112636052(TNFRSF9)

MLEU:

105540720(TNFRSF9)

RRO:	104657559(TNFRSF9)

RBB:	108517919(TNFRSF9)

TFN:	117093378(TNFRSF9)

PTEH:

111544674(TNFRSF9)

CANG:

105509148(TNFRSF9)

CJC:	100412493(TNFRSF9)

SBQ:	101053479(TNFRSF9)

CIMI:

108282391(TNFRSF9)

CSYR:

103260861(TNFRSF9)

MMUR:

105886090(TNFRSF9)

LCAT:

123634531(TNFRSF9)

PCOQ:

105824914(TNFRSF9)

OGA:	100951885(TNFRSF9)

MMU:	21942(Tnfrsf9)

MCAL:

110293276(Tnfrsf9)

MPAH:

110323544(Tnfrsf9)

RNO:	500590(Tnfrsf9)

MCOC:

116095690(Tnfrsf9)

ANU:	117709570(Tnfrsf9)

MUN:	110560424(Tnfrsf9)

CGE:	100761423(Tnfrsf9)

MAUA:

101829103(Tnfrsf9)

PROB:

127213449(Tnfrsf9)

PLEU:

114702599(Tnfrsf9)

MORG:

121441831 121448809

MFOT:

126508270

AAMP:

119817669(Tnfrsf9)

NGI:	103725142(Tnfrsf9)

HGL:	101708619(Tnfrsf9)

CPOC:

100730923(Tnfrsf9)

CCAN:

109699422(Tnfrsf9)

DORD:

105998424(Tnfrsf9)

DSP:	122121470(Tnfrsf9)

PLOP:

125354528(Tnfrsf9)

NCAR:

124958020

MMMA:

107155538(Tnfrsf9)

OCU:

100348914

OPI:	101536370(TNFRSF9)

TUP:	102471632(TNFRSF9)

GVR:	103609571(TNFRSF9)

CFA:	608274(TNFRSF9)

CLUD:

112646898(TNFRSF9)

VVP:	112924681(TNFRSF9)

VLG:	121500226(TNFRSF9)

NPO:	129497352(TNFRSF9)

AML:	100475396(TNFRSF9)

UMR:	103666689(TNFRSF9)

UAH:	113270556(TNFRSF9)

UAR:	123796170(TNFRSF9)

ELK:

111154790

LLV:

125099031

MPUF:

101684583(TNFRSF9)

MNP:	132000886(TNFRSF9)

MLK:	131810057(TNFRSF9)

NVS:	122898568(TNFRSF9)

ORO:	101380574(TNFRSF9)

EJU:	114213356(TNFRSF9)

ZCA:	113936002(TNFRSF9)

MLX:	118020048(TNFRSF9)

NSU:	110574643(TNFRSF9)

LWW:	102747127(TNFRSF9)

FCA:	101096582(TNFRSF9)

PYU:	121020217(TNFRSF9)

PCOO:

112848597(TNFRSF9)

PBG:	122479889(TNFRSF9)

PVIV:

125173103(TNFRSF9)

LRUF:

124515737

PTG:	102959838(TNFRSF9)

PPAD:

109274042(TNFRSF9)

PUC:

125913153

AJU:

106982205

HHV:	120233631(TNFRSF9)

BTA:	520341(TNFRSF9)

BOM:	102287795(TNFRSF9)

BIU:	109570817(TNFRSF9)

BBUB:

102396760(TNFRSF9)

BBIS:

104995882(TNFRSF9)

CHX:	102177910(TNFRSF9)

OAS:	101119742(TNFRSF9)

BTAX:

128061827(TNFRSF9)

ODA:	120880165(TNFRSF9)

CCAD:

122452514(TNFRSF9)

MBEZ:

129551082(TNFRSF9)

SSC:	100519368(TNFRSF9)

CFR:	102503735(TNFRSF9)

CBAI:

105071006(TNFRSF9)

CDK:	105106985(TNFRSF9)

VPC:	102531006(TNFRSF9)

BACU:

103019992(TNFRSF9)

BMUS:

118881883(TNFRSF9)

OOR:	101275006(TNFRSF9)

DLE:	111187168(TNFRSF9)

PCAD:

102977317(TNFRSF9)

PSIU:

116740590(TNFRSF9)

NASI:

112402797(TNFRSF9)

ECB:	100058657(TNFRSF9)

EPZ:	103561707(TNFRSF9)

EAI:	106844331(TNFRSF9)

MYB:	102247177(TNFRSF9)

MYD:	102770104(TNFRSF9)

MMYO:

118677699(TNFRSF9)

MLF:	102443254(TNFRSF9)

PKL:	118731947(TNFRSF9)

EFUS:

103295404(TNFRSF9)

MNA:	107538341(TNFRSF9)

DRO:	112299064(TNFRSF9)

SHON:

118998126(TNFRSF9)

AJM:	119055927(TNFRSF9)

PDIC:

114496847(TNFRSF9)

PHAS:

123832026(TNFRSF9)

MMF:	118626999(TNFRSF9)

PPAM:

129075608(TNFRSF9)

RFQ:	117027456(TNFRSF9)

PALE:

102891700(TNFRSF9)

PGIG:

120585858(TNFRSF9)

PVP:	105297664(TNFRSF9)

RAY:	107517707(TNFRSF9)

MJV:	108391156(TNFRSF9)

TOD:	119235436(TNFRSF9)

SARA:

101547770(TNFRSF9)

SETR:

126011612(TNFRSF9)

LAV:	100665125(TNFRSF9)

TMU:

101356828

ETF:	101648773(TNFRSF9)

MDO:	100011698(TNFRSF9)

GAS:	123255224 123256648(TNFRSF9)

SHR:	100927255(TNFRSF9)

AFZ:

127555918

PCW:	110199795(TNFRSF9)

OAA:	100073680(TNFRSF9)

GGA:	419365(TNFRSF9)

PCOC:

116242665(TNFRSF9)

MGP:	104914113(TNFRSF9)

CJO:	107323466(TNFRSF9)

TPAI:

128084943(TNFRSF9)

LMUT:

125703365(TNFRSF9)

NMEL:

110408732(TNFRSF9)

APLA:

101794213(TNFRSF9)

ACYG:

106047226(TNFRSF9)

CATA:

118253429(TNFRSF9)

AFUL:

116497757(TNFRSF9)

TGU:	100220654(TNFRSF9)

LSR:	110472529(TNFRSF9)

SCAN:

103820940(TNFRSF9)

PMOA:

120511070(TNFRSF9)

OTC:	121344125(TNFRSF9)

PRUF:

121358461(TNFRSF9)

GFR:	102036898(TNFRSF9)

FAB:	101819114(TNFRSF9)

OMA:	130261620(TNFRSF9)

PHI:	102112077(TNFRSF9)

PMAJ:

107213494(TNFRSF9)

CCAE:

111938469(TNFRSF9)

CCW:	104693368(TNFRSF9)

CBRC:

103616160(TNFRSF9)

ETL:	114060123(TNFRSF9)

ZAB:	102075424(TNFRSF9)

SVG:	106857655(TNFRSF9)

MMEA:

130579077(TNFRSF9)

HRT:	120762231(TNFRSF9)

FCH:	114015476(TNFRSF9)

CLV:	102088472(TNFRSF9)

PLET:

104618910(TNFRSF9)

EHS:	104515060(TNFRSF9)

ACUN:

113488000(TNFRSF9)

TALA:

116961625(TNFRSF9)

PADL:

103924872(TNFRSF9)

AFOR:

103894748(TNFRSF9)

ACHC:

115342667(TNFRSF9)

AGEN:

126043287

GCL:

127024900

SHAB:

115617497(TNFRSF9)

ACAR:

114818601(TNFRSF9)

RTD:	128918410(TNFRSF9)

AAM:	106496699(TNFRSF9)

AROW:

112975484(TNFRSF9)

NPD:	112957445(TNFRSF9)

DNE:	112989037(TNFRSF9)

SCAM:

104139063(TNFRSF9)

ASN:	102385217(TNFRSF9)

AMJ:	102557646(TNFRSF9)

CPOO:

109314478(TNFRSF9)

GGN:	109293531(TNFRSF9)

CMY:	102932513(TNFRSF9)

CCAY:

125624228(TNFRSF9)

DCC:	119844926(TNFRSF9)

CPIC:

101952636(TNFRSF9)

TST:	117868007(TNFRSF9)

CABI:

116815436(TNFRSF9)

MRV:	120387717(TNFRSF9)

ASAO:

132764975(TNFRSF9)

PVT:	110082443(TNFRSF9)

SUND:

121936361(TNFRSF9)

TSR:

106556563

PGUT:

117656615(TNFRSF9)

APRI:

131187204(TNFRSF9)

NSS:

113427801

VKO:	123018608(TNFRSF9)

PMUA:

114602368(TNFRSF9) 114602943

PRAF:

128419595(TNFRSF9)

ZVI:	118087634(TNFRSF9)

HCG:	128338738(TNFRSF9)

EMC:	129344634(TNFRSF9)

XLA:	108696592(tnfrsf9.L) 108697673

XTR:	100489585(tnfrsf9)

RTEM:

120915780(TNFRSF9)

BGAR:

122926775 122926891(TNFRSF9)

MUO:	115456740(TNFRSF9)

GSH:	117348789(TNFRSF9)

DRE:	100151629(tnfrsf9b) 678622(tnfrsf9a)

SRX:	107708826 107713486 107718814 107750268 107751232 107756611 107756612

SANH:

107654368 107654436 107656554 107666983 107695761

SGH:	107584513 107586554 107592895

CCAR:

109047958 109088859 109088864 109089136 109094367 109098971 109101660

CAUA:

113041460 113055526 113065278 113065626 113095957 113110874

CGIB:

127944893 127968628 128011511 128022068

PTET:

122328652(tnfrsf9a) 122353626(tnfrsf9b)

LROH:

127154498(tnfrsf9a) 127172777(tnfrsf9b)

OMC:	131531537(tnfrsf9a) 131549857(tnfrsf9b)

PPRM:

120463565(tnfrsf9a) 120491968 120491969

RKG:	130075649(tnfrsf9a) 130088519(tnfrsf9b)

MAMB:

125257147(tnfrsf9b) 125260411(tnfrsf9a)

CIDE:

127504475 127522397

MASI:

127419513 127427913

TROS:

130545199(tnfrsf9a) 130571311(tnfrsf9b)

TDW:	130409174(tnfrsf9a) 130409950(tnfrsf9b)

MANU:

129427453(tnfrsf9b) 129430645(tnfrsf9a)

IPU:	108254817(tnfrsf9b) 108276046(tnfrsf9a)

IFU:	128619801(tnfrsf9a) 128624728(tnfrsf9b)

PHYP:

113530812 113537811

SMEO:

124402511(tnfrsf9b)

TFD:	113657226(tnfrsf9b) 113658166(tnfrsf9a)

TVC:	132838398(tnfrsf9b) 132862606(tnfrsf9a)

AMEX:

103023389(tnfrsf9) 103036568 103037250

CMAO:

118799642(tnfrsf9b) 118822094(tnfrsf9a)

EEE:	113567918 113581958

CHAR:

116220324(tnfrsf9a)

TRU:

105416294

TNG:	GSTEN00023579G001

LCO:	104920529 104924674

NCC:

104959989

TBEN:

117483419(tnfrsf9a)

PGEO:

117449199(tnfrsf9a)

GAT:	120829534(tnfrsf9a)

MSAM:

119905232

CUD:	121517110(tnfrsf9a)

ALAT:

119022267(tnfrsf9a)

MZE:

101485252

ONL:

102083188

OAU:	116319498(tnfrsf9a)

XMA:

XCO:

XHE:

PRET:

PFOR:

103139032 103143998 103144001

PLAI:

106954284

PMEI:

106929511 106931673

GAF:	122839510(tnfrsf9a)

PPRL:

129370359(tnfrsf9a)

CVG:

107083927

CTUL:

119782001(tnfrsf9a)

NFU:

107390469

KMR:	108232104(tnfrsf9a)

ALIM:

AOCE:

CSEM:

POV:

HHIP:

117765219(tnfrsf9a)

LCF:	108882155(tnfrsf9a)

SDU:

111235018

SLAL:

111654192

XGL:	120803734(tnfrsf9a)

HCQ:

109512934

SBIA:

133515272

PEE:	133401878(tnfrsf9a)

PTAO:

BPEC:

MALB:

SJO:

SASA:

STRU:

OTW:	112216167 112221925(tnfrsf9a)

OMY:	110492146 110532464

OGO:	124045907(tnfrsf9a)

ONE:	115102348 115119277

OKI:	109869211 109908145

OKE:	118359869 118360859

SALP:

111966625 112081021

SNH:	120058629 120061327

CCLU:

121537533 121545652

ELS:

105022388

SFM:	108933510 108938184

PKI:

111859103

AANG:

118208104(tnfrsf9a) 118210870

LOC:

107075569

PSPA:

121302011

ARUT:

117425243(cd27) 117425313 117425934 117963574 117963776

LCM:	106703159(TNFRSF9)

CMK:

103184229

RTP:

109913778

CPLA:

122540143 122540399

HOC:	132833627 132833778

CRG:

105346861

PMAX:

117345150

» show all

Reference

PMID:8088337

Authors

Alderson MR, Smith CA, Tough TW, Davis-Smith T, Armitage RJ, Falk B, Roux E, Baker E, Sutherland GR, Din WS

Title

Molecular and biological characterization of human 4-1BB and its ligand.

Journal

Eur J Immunol 24:2219-27 (1994)
DOI:10.1002/eji.1830240943

Sequence

[hsa:3604]

Reference

PMID:8639902

Authors

Schwarz H, Blanco FJ, von Kempis J, Valbracht J, Lotz M

Title

ILA, a member of the human nerve growth factor/tumor necrosis factor receptor family, regulates T-lymphocyte proliferation and survival.

Journal

Blood 87:2839-45 (1996)

LinkDB

DBGET integrated database retrieval system