KEGG ORTHOLOGY: K05426

ORTHOLOGY: K05426

Entry

K05426                      KO

Symbol

IL23A

Name

interleukin 23 subunit alpha

Pathway

map04060

Cytokine-cytokine receptor interaction

map04625

C-type lectin receptor signaling pathway

map04630

JAK-STAT signaling pathway

map04659

Th17 cell differentiation

map05133

Pertussis

map05152

Tuberculosis

map05200

Pathways in cancer

map05321

Inflammatory bowel disease

map05323

Rheumatoid arthritis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05426  IL23A; interleukin 23 subunit alpha
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05426  IL23A; interleukin 23 subunit alpha
09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    K05426  IL23A; interleukin 23 subunit alpha
   04659 Th17 cell differentiation
    K05426  IL23A; interleukin 23 subunit alpha
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05426  IL23A; interleukin 23 subunit alpha
  09171 Infectious disease: bacterial
   05133 Pertussis
    K05426  IL23A; interleukin 23 subunit alpha
   05152 Tuberculosis
    K05426  IL23A; interleukin 23 subunit alpha
  09163 Immune disease
   05323 Rheumatoid arthritis
    K05426  IL23A; interleukin 23 subunit alpha
   05321 Inflammatory bowel disease
    K05426  IL23A; interleukin 23 subunit alpha
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K05426  IL23A; interleukin 23 subunit alpha
Cytokines and neuropeptides [BR:ko04052]
Cytokines
  Interleukins
   K05426  IL23A; interleukin 23 subunit alpha

Other DBs

GO:

0045519

Genes

HSA:	51561(IL23A)

PTR:	467036(IL23A)

PPS:	100974265(IL23A)

GGO:	101146347(IL23A)

PON:	100452384(IL23A)

NLE:	100586740(IL23A)

HMH:	116480912(IL23A)

MCC:	712627(IL23A)

MCF:	102128555(IL23A)

MTHB:

126931219

MNI:	105474145(IL23A)

CSAB:

103238523(IL23A)

CATY:

105587299(IL23A)

PANU:

101011696(IL23A)

TGE:	112634338(IL23A)

MLEU:

105529947(IL23A)

RRO:	104673677(IL23A)

RBB:	108516020(IL23A)

TFN:	117089933(IL23A)

PTEH:

111541849(IL23A)

CANG:

105500548(IL23A)

CJC:	100414179(IL23A)

SBQ:	101034582(IL23A)

CIMI:

108309777(IL23A)

CSYR:

103272705(IL23A)

MMUR:

105865330(IL23A)

LCAT:

123639651(IL23A)

PCOQ:

105817087(IL23A)

OGA:	100943872(IL23A)

MMU:	83430(Il23a)

MCAL:

110303939(Il23a)

MPAH:

110327099(Il23a)

RNO:	155140(Il23a)

MCOC:

116075994(Il23a)

ANU:	117696811(Il23a)

MUN:	110559386(Il23a)

CGE:	100765061(Il23a)

MAUA:

101827862(Il23a)

PROB:

127215845(Il23a)

PLEU:

114681748(Il23a)

MORG:

121455460(Il23a)

MFOT:

126492059

AAMP:

119803217(Il23a)

NGI:	103746524(Il23a)

HGL:	101707902(Il23a)

CPOC:

100135557(Il23a)

CCAN:

109686122(Il23a)

DORD:

105988878(Il23a)

DSP:	122124119(Il23a)

PLOP:

125362876(Il23a)

NCAR:

124982636

MMMA:

107139832(Il23a)

OCU:	100352065 127487391

OPI:	101536433(IL23A)

TUP:	102477558(IL23A)

GVR:	103594015(IL23A)

CFA:	481110(IL23A)

CLUD:

112678015(IL23A)

VVP:	112922380(IL23A)

VLG:	121491361(IL23A)

NPO:	129511793(IL23A)

AML:	100471919(IL23A)

UMR:	103656219(IL23A)

UAH:	113256421(IL23A)

UAR:	123787248(IL23A)

ELK:

111160242

LLV:

125106750

MPUF:

101687314(IL23A)

MNP:	132019805(IL23A)

MLK:	131838601(IL23A)

NVS:	122892295(IL23A)

ORO:	101367844(IL23A)

EJU:	114215002(IL23A)

ZCA:	113922227(IL23A)

MLX:	118008712(IL23A)

NSU:	110577791(IL23A)

LWW:	102739313(IL23A)

FCA:	654423(IL23A)

PYU:	121040925(IL23A)

PCOO:

112863908(IL23A)

PBG:	122473644(IL23A)

PVIV:

125170215(IL23A)

LRUF:

124501368

PTG:	102967682(IL23A)

PPAD:

109270334(IL23A)

PUC:

125920272

AJU:

106986881

HHV:	120219938(IL23A)

BTA:	511022(IL23A)

BOM:	102277988(IL23A)

BIU:	109559359(IL23A)

BBUB:

102413348(IL23A)

BBIS:

104988073(IL23A)

CHX:	102190023(IL23A)

OAS:	100462692(IL23A)

BTAX:

128047301(IL23A)

ODA:	120857450(IL23A)

CCAD:

122427314(IL23A)

MBEZ:

129537130(IL23A)

SSC:	100155546(IL23A)

CFR:	102511458(IL23A)

CBAI:

105075885(IL23A)

CDK:	105086361(IL23A)

VPC:	102524771(IL23A)

BACU:

103000924(IL23A)

BMUS:

118901553(IL23A)

LVE:	103081458(IL23A)

OOR:	101281838(IL23A)

DLE:	111173709(IL23A)

PCAD:

102981863(IL23A)

PSIU:

116760221(IL23A)

NASI:

112394098(IL23A)

ECB:	100034230(IL23A)

EPZ:	103557547(IL23A)

EAI:	106832958(IL23A)

MYB:	102240355(IL23A)

MYD:	102765952(IL23A)

MMYO:

118651144(IL23A)

MLF:	102431172(IL23A)

PKL:	118729132(IL23A)

EFUS:

103292428(IL23A)

MNA:	107546155(IL23A)

DRO:	112318951(IL23A)

SHON:

118976004(IL23A)

AJM:	119040315(IL23A)

PDIC:

114513716(IL23A)

PHAS:

123813062(IL23A)

MMF:	118623879(IL23A)

PPAM:

129075779(IL23A)

HAI:	109396832(IL23A)

RFQ:	117028062(IL23A)

PALE:

102879394(IL23A)

PGIG:

120604919(IL23A)

PVP:	105302575(IL23A)

RAY:	107521235(IL23A)

MJV:	108402233(IL23A)

TOD:	119248486(IL23A)

SARA:

101548978(IL23A)

SETR:

126023039(IL23A)

LAV:	100656085(IL23A)

TMU:

101349206

ETF:	101661380(IL23A)

DNM:	101423062(IL23A)

GAS:	123250206(IL23A)

SHR:	100933427(IL23A)

AFZ:

127537889

PCW:	110210932(IL23A)

OAA:	100087533(IL23A)

GGA:	100858964(IL23A)

PCOC:

116239828(IL23A)

MGP:	104916176(IL23A)

CJO:	107325846(IL23A)

TPAI:

128071948(IL23A)

LMUT:

125685610(IL23A)

NMEL:

110389254(IL23A)

APLA:

119714619(IL23A)

CATA:

118260200(IL23A)

AFUL:

116499869(IL23A)

TGU:	115491463(IL23A)

LSR:	110477058(IL23A)

PMOA:

120505745(IL23A)

OTC:	121337503(IL23A)

PRUF:

121358948(IL23A)

OMA:	130265838(IL23A)

PHI:	102112090(IL23A)

SVG:	106863159(IL23A)

HRT:	120764391(IL23A)

FPG:	101912740(IL23A)

FCH:	102055360(IL23A)

NNI:	104013742(IL23A)

TALA:

116963076(IL23A)

ACHC:

115351361(IL23A)

HLE:	104830350(IL23A)

AGEN:

126046517

SHAB:

115618726(IL23A)

RTD:	128903216(IL23A)

AROW:

112974236(IL23A)

NPD:	112955621(IL23A)

DNE:	112996980(IL23A)

ASN:	102378987(IL23A)

AMJ:	106737722(IL23A)

CPOO:

109322970(IL23A)

GGN:	109295423(IL23A)

CMY:	119564285(IL23A)

CCAY:

125627855(IL23A)

DCC:	119845695(IL23A)

CPIC:

103306702(IL23A)

MRV:	120391253(IL23A)

ACS:	103277778(il23a)

ASAO:

132766598(IL23A)

PVT:	110075238(IL23A)

SUND:

121920449

PBI:	112540372(IL23A)

PGUT:

117663100(IL23A)

APRI:

131190588(IL23A)

PTEX:

113447301(IL23A)

NSS:	113420162(IL23A)

PMUA:

114592815

ZVI:

118081589

RTEM:

120928240(IL23A)

GSH:

IPU:

IFU:

PHYP:

SMEO:

CTUL:

OMY:

OGO:

LOC:

CPLA:

HOC:

LERI:

Reference

PMID:21585245

Authors

Duvallet E, Semerano L, Assier E, Falgarone G, Boissier MC

Title

Interleukin-23: a key cytokine in inflammatory diseases.

Journal

Ann Med 43:503-11 (2011)
DOI:10.3109/07853890.2011.577093

Reference

PMID:11114383

Authors

Oppmann B, Lesley R, Blom B, Timans JC, Xu Y, Hunte B, Vega F, Yu N, Wang J, Singh K, Zonin F, Vaisberg E, Churakova T, Liu M, Gorman D, Wagner J, Zurawski S, Liu Y, Abrams JS, Moore KW, Rennick D, de Waal-Malefyt R, Hannum C, Bazan JF, Kastelein RA

Title

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.

Journal

Immunity 13:715-25 (2000)
DOI:10.1016/S1074-7613(00)00070-4

Sequence

[hsa:51561]

LinkDB

DBGET integrated database retrieval system