Entry
Symbol
MCEE, epi
Name
methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:
5.1.99.1 ]
Pathway
map00280 Valine, leucine and isoleucine degradation
map00630 Glyoxylate and dicarboxylate metabolism
map00720 Carbon fixation pathways in prokaryotes
map01120 Microbial metabolism in diverse environments
Module
M00375 Hydroxypropionate-hydroxybutylate cycle
M00376 3-Hydroxypropionate bi-cycle
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA
Reaction
R02765 methylmalonyl-CoA epimerase
R09979 (2S)-ethylmalonyl-CoA epimerase
Disease
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
K05606 MCEE, epi; methylmalonyl-CoA/ethylmalonyl-CoA epimerase
00640 Propanoate metabolism
K05606 MCEE, epi; methylmalonyl-CoA/ethylmalonyl-CoA epimerase
09102 Energy metabolism
00720 Carbon fixation pathways in prokaryotes
K05606 MCEE, epi; methylmalonyl-CoA/ethylmalonyl-CoA epimerase
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
K05606 MCEE, epi; methylmalonyl-CoA/ethylmalonyl-CoA epimerase
Enzymes [BR:ko01000 ]
5. Isomerases
5.1 Racemases and epimerases
5.1.99 Acting on other compounds
5.1.99.1 methylmalonyl-CoA epimerase
K05606 MCEE, epi; methylmalonyl-CoA/ethylmalonyl-CoA epimerase
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Genes
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Taxonomy UniProt
Reference
Authors
Bobik TA, Rasche ME
Title
Identification of the human methylmalonyl-CoA racemase gene based on the analysis of prokaryotic gene arrangements. Implications for decoding the human genome.
Journal
Sequence
Reference
Authors
Ramos-Vera WH, Weiss M, Strittmatter E, Kockelkorn D, Fuchs G
Title
Identification of missing genes and enzymes for autotrophic carbon fixation in crenarchaeota.
Journal
Reference
Authors
Erb TJ, Retey J, Fuchs G, Alber BE
Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
Journal
Sequence
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