KEGG ORTHOLOGY: K06472

ORTHOLOGY: K06472

Entry

K06472                      KO

Symbol

FCGR2A, CD32

Name

low affinity immunoglobulin gamma Fc receptor II-a

Pathway

map04145

Phagosome

map04380

Osteoclast differentiation

map04611

Platelet activation

map04613

Neutrophil extracellular trap formation

map04666

Fc gamma R-mediated phagocytosis

map05130

Pathogenic Escherichia coli infection

map05135

Yersinia infection

map05140

Leishmaniasis

map05150

Staphylococcus aureus infection

map05152

Tuberculosis

map05171

Coronavirus disease - COVID-19

map05322

Systemic lupus erythematosus

Disease

H00080

Systemic lupus erythematosus

H00218

Cystic fibrosis

H00361

Malaria

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
   04613 Neutrophil extracellular trap formation
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
   04666 Fc gamma R-mediated phagocytosis
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
   05135 Yersinia infection
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
   05150 Staphylococcus aureus infection
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
   05152 Tuberculosis
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
  09163 Immune disease
   05322 Systemic lupus erythematosus
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
Membrane trafficking [BR:ko04131]
Endocytosis
  Phagocytosis
   Fc receptors
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
CD molecules [BR:ko04090]
Proteins
  K06472  CD32a, FCGR2A; Fc fragment of IgG, low affinity IIa, receptor for (CD32)

Other DBs

GO:

0019770

Genes

HSA:	2212(FCGR2A)

PTR:	450194(FCGR2A)

PPS:	100991644(FCGR2A)

GGO:	101130688(FCGR2A)

PON:	100455333(FCGR2A)

NLE:	101176530(FCGR2A)

HMH:	116473329(FCGR2A)

MCC:	719996(FCGR2A)

MCF:	102143568(FCGR2A)

CSAB:

103223676(FCGR2A)

CATY:

105589239(FCGR2A)

PANU:

101009922(FCGR2A)

TGE:	112609477(FCGR2A)

MLEU:

105551007(FCGR2A) 105551015

RRO:	104669518(FCGR2A)

RBB:	108542586(FCGR2A)

TFN:	117074579(FCGR2A)

PTEH:

111525036(FCGR2A)

CANG:

105519604(FCGR2A)

CJC:	100387574(FCGR2A)

SBQ:	101040113(FCGR2A)

CIMI:

108293619(FCGR2A)

CSYR:

103256413(FCGR2A)

MMUR:

105873561(FCGR2A)

PCOQ:

105806468(FCGR2A)

OGA:	100959832(FCGR2A)

MMU:	14131(Fcgr3)

MCAL:

110288995

MPAH:

110321588

RNO:	134481532 498276(Fcgr2al1)

MCOC:

116103299(Fcgr2a)

ANU:	117712636(Fcgr2a)

MUN:	110554429(Fcgr2a)

CGE:

103161891

MAUA:

101831114

PROB:

127223560(Fcgr2a)

PLEU:

119086087(Fcgr2a)

MORG:

121442024 121455102

MFOT:

126496491 126496539 126511151

AAMP:

119827207(Fcgr2a)

NGI:	103746769(Fcgr2a)

HGL:	101700630(Fcgr2a)

CPOC:

101787193(Fcgr2a)

CCAN:

109693506(Fcgr2a)

DORD:

DSP:

PLOP:

NCAR:

MMMA:

107147464(Fcgr2a)

OCU:

100338413

OPI:

101522808

GVR:	103582477(FCGR2A)

BTA:	782652(FCGR2A)

BOM:

BIU:

BBUB:

BBIS:

CHX:

OAS:

BTAX:

CCAD:

MBEZ:

SSC:

CFR:

CBAI:

CDK:

BACU:

BMUS:

LVE:

PCAD:

PSIU:

ECB:	100051733 100065733 100147417

EPZ:	103540857 103540858(FCGR2A)

EAI:	106831115(FCGR2A)

MYB:

MYD:

MMYO:

MLF:

PKL:

EFUS:

MNA:

DRO:

SHON:

AJM:

MMF:

PALE:

RAY:

LAV:	104846329(FCGR2A)

TMU:

101350744

PCW:	110209907 110209911

SANH:

CAUA:

TRU:

TFS:

LCO:	109140375 109140376

TBEN:

117469800 117469801 117469831 117469832

PGEO:

117443069 117443075

GACU:

117550342 117550344 117562655

EMAC:

134876195 134876211

ELY:	117245710 117245912 117245954 117245957

EFO:	125883976 125884181 125884440

PLEP:

121938216 121938869 121962104 121962492

SLUC:

116037670 116045163 116052089

ECRA:

117934643 117935165

ESP:

116696238

PFLV:

114545541 114546079 114546080 114546200

PPUG:

119223025

AFB:	129093653 129093715 129116533 129116537

CLUM:

117748111

MSAM:

119894681 119913022 119913023

SCHU:

122869696 122870258

CUD:	121504085 121504361 121504770

ALAT:

119026854 119026899

OAU:	116318550 120437377

OLA:

105356322

OML:

112156230

CSAI:

133420411

XMA:	111611193 111611255

XCO:

114156964

XHE:	116732172 116732504 116733134

PRET:

103460539 103480243 103480863

PFOR:

103129349 103129350 103130536 103130986 103131813

PLAI:

106935121 106938394 106940071 106940659 106941699

PMEI:

106905133 106910704 106912573 106912574

GAF:	122820581 122820714 122821047

PPRL:

129351343 129351368 129352352 129376493 129376544 129376589

CTUL:

119796607 119798683

GMU:	124880301 124880423 124880923 124881269

KMR:

MCEP:

SSEN:

SMAU:

SDU:

XGL:

BPEC:

BSPL:

SJO:	128383548 128383594 128383613 128384122

SASA:

SALP:

ELS:

ARUT:

Reference

PMID:2824655

Authors

Stuart SG, Trounstine ML, Vaux DJ, Koch T, Martens CL, Mellman I, Moore KW

Title

Isolation and expression of cDNA clones encoding a human receptor for IgG (Fc gamma RII).

Journal

J Exp Med 166:1668-84 (1987)
DOI:10.1084/jem.166.6.1668

Sequence

[hsa:2212]

Reference

PMID:19011614

Authors

Lu J, Marnell LL, Marjon KD, Mold C, Du Clos TW, Sun PD

Title

Structural recognition and functional activation of FcgammaR by innate pentraxins.

Journal

Nature 456:989-92 (2008)
DOI:10.1038/nature07468

LinkDB

DBGET integrated database retrieval system