KEGG ORTHOLOGY: K06564

ORTHOLOGY: K06564

Entry

K06564                      KO

Symbol

IGF2R, CD222

Name

insulin-like growth factor 2 receptor

Pathway

map03266

Virion - Herpesvirus

map04142

Lysosome

map04144

Endocytosis

Disease

H00048

Hepatocellular carcinoma

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09125 Information processing in viruses
   03266 Virion - Herpesvirus
    K06564  IGF2R, CD222; insulin-like growth factor 2 receptor
09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K06564  IGF2R, CD222; insulin-like growth factor 2 receptor
   04142 Lysosome
    K06564  IGF2R, CD222; insulin-like growth factor 2 receptor
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K06564  IGF2R, CD222; insulin-like growth factor 2 receptor
   04090 CD molecules
    K06564  IGF2R, CD222; insulin-like growth factor 2 receptor
   04091 Lectins
    K06564  IGF2R, CD222; insulin-like growth factor 2 receptor
Exosome [BR:ko04147]
Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K06564  IGF2R, CD222; insulin-like growth factor 2 receptor
CD molecules [BR:ko04090]
Proteins
  K06564  CD222, IGF2R; insulin-like growth factor 2 receptor
Lectins [BR:ko04091]
P-type lectins
  K06564  IGF2R, CD222; insulin-like growth factor 2 receptor

Other DBs

GO:	0005010 0031995

Genes

HSA:	3482(IGF2R)

PTR:	463112(IGF2R)

PPS:	100968050(IGF2R)

GGO:	101147241(IGF2R)

PON:	100432010(IGF2R)

NLE:	115834474(IGF2R)

HMH:	116473584(IGF2R)

MCC:	703220(IGF2R)

MCF:	102117130(IGF2R)

MTHB:

126953646

MNI:	105492011(IGF2R)

CSAB:

103240833(IGF2R)

CATY:

105581461(IGF2R)

PANU:

101005933(IGF2R)

TGE:	112622371(IGF2R)

MLEU:

105536571(IGF2R)

RRO:	104666428(IGF2R)

RBB:	108516180(IGF2R)

TFN:	117096923(IGF2R)

PTEH:

111547340(IGF2R)

CANG:

105506730(IGF2R)

CJC:	100412577(IGF2R)

SBQ:	101041450(IGF2R)

CIMI:

108310865(IGF2R)

CSYR:

103276929(IGF2R)

MMUR:

105868590(IGF2R)

LCAT:

123633432(IGF2R)

PCOQ:

105812399(IGF2R)

OGA:	100950928(IGF2R)

MMU:	16004(Igf2r)

MCAL:

110283910(Igf2r)

MPAH:

110338103(Igf2r)

RNO:	25151(Igf2r)

MCOC:

116076834(Igf2r)

ANU:	117700113(Igf2r)

MUN:	110541065(Igf2r)

CGE:	100762916(Igf2r)

MAUA:

101839699(Igf2r)

PROB:

127237713(Igf2r)

PLEU:

114691369(Igf2r)

MORG:

121466371(Igf2r)

MFOT:

126497712

AAMP:

119820331(Igf2r)

NGI:	103734802(Igf2r)

HGL:	101707470(Igf2r)

CPOC:

100725901(Igf2r)

CCAN:

109682998 109682999

DORD:

105991800(Igf2r)

DSP:	122116120(Igf2r)

PLOP:

125357465(Igf2r)

NCAR:

124988139

MMMA:

107153168(Igf2r)

OCU:

100009573

OPI:	101516697(IGF2R)

TUP:	102479171(IGF2R)

GVR:	103602345(IGF2R)

CFA:	484067(IGF2R)

CLUD:

112644393(IGF2R)

VVP:	112935139(IGF2R)

VLG:	121484342(IGF2R)

NPO:	129500165(IGF2R)

AML:	100478504(IGF2R)

UMR:	103660899(IGF2R)

UAH:	113259623(IGF2R)

UAR:	123797545(IGF2R)

ELK:

111158747

LLV:

125103268

MPUF:

101690424(IGF2R)

MNP:	132018441(IGF2R)

MLK:	131833399(IGF2R)

NVS:	122902809(IGF2R)

ORO:	101381369(IGF2R)

EJU:	114209355(IGF2R)

ZCA:	113926509(IGF2R)

MLX:	118001837 118001960

NSU:	110583166(IGF2R)

LWW:	102745248(IGF2R)

FCA:	100500935(IGF2R)

PYU:	121013221(IGF2R)

PCOO:

112862218(IGF2R)

PBG:	122490152(IGF2R)

PVIV:

125165397(IGF2R)

LRUF:

124528977

PTG:	102951842(IGF2R)

PPAD:

109245394(IGF2R)

PUC:

125939030

AJU:

106965972

HHV:	120223340(IGF2R)

BTA:	281849(IGF2R)

BOM:	102283695(IGF2R)

BIU:	109564096(IGF2R)

BBUB:

102403952(IGF2R)

BBIS:

104989286(IGF2R)

CHX:	100860744(IGF2R)

OAS:	443500(IGF2R)

BTAX:

128053042(IGF2R)

ODA:	120862818(IGF2R)

CCAD:

122433918(IGF2R)

MBEZ:

129560720(IGF2R)

SSC:	397214(IGF2R)

CFR:	102520978(IGF2R)

CBAI:

105077369(IGF2R)

CDK:	105100381(IGF2R)

VPC:	102525970(IGF2R)

BACU:

103003624(IGF2R)

BMUS:

118904910(IGF2R)

LVE:	103074704(IGF2R)

OOR:	101278998(IGF2R)

DLE:	111167631(IGF2R)

PCAD:

102982311(IGF2R)

PSIU:

116763720(IGF2R)

NASI:

112401565(IGF2R)

ECB:	100058539(IGF2R)

EPZ:	103558448(IGF2R)

EAI:	106842007(IGF2R)

MYB:	102262413(IGF2R)

MYD:	102756829(IGF2R)

MMYO:

118660665(IGF2R)

MLF:	102436544(IGF2R)

PKL:	118705283(IGF2R)

EFUS:

103297953(IGF2R)

MNA:	107535725(IGF2R)

DRO:	112297159(IGF2R)

SHON:

118995580(IGF2R)

AJM:	119034987(IGF2R)

PDIC:

114494500(IGF2R)

PHAS:

123821329(IGF2R)

MMF:	118620944(IGF2R)

PPAM:

129088288(IGF2R)

HAI:	109394012(IGF2R)

RFQ:	117017087(IGF2R)

PALE:

102887509(IGF2R)

PGIG:

120617503(IGF2R)

PVP:	105305675(IGF2R)

RAY:	107514750(IGF2R)

MJV:	108409361(IGF2R)

TOD:	119253030(IGF2R)

SARA:

101558660(IGF2R)

SETR:

125996372(IGF2R)

LAV:	100664301(IGF2R)

TMU:

101341440

ETF:	101641506(IGF2R)

DNM:	101431452(IGF2R)

MDO:	100027969(IGF2R)

GAS:	123243739(IGF2R)

SHR:	100926926(IGF2R)

AFZ:

127562388

PCW:	110208612(IGF2R)

OAA:	790958(IGF2R)

GGA:	395817(IGF2R)

PCOC:

116242017(IGF2R)

MGP:	100549919(IGF2R)

CJO:	107311520(IGF2R)

TPAI:

128080885(IGF2R)

LMUT:

125689958(IGF2R)

NMEL:

110395821(IGF2R)

APLA:

101795708(IGF2R)

ACYG:

106039512(IGF2R)

CATA:

118243866(IGF2R)

AFUL:

116487931(IGF2R)

TGU:	100232425(IGF2R)

LSR:	110476046(IGF2R)

SCAN:

103820613(IGF2R)

PMOA:

120501491(IGF2R)

OTC:	121346135(IGF2R)

PRUF:

121354816(IGF2R)

GFR:	102040455(IGF2R)

FAB:	101808719(IGF2R)

OMA:	130251452(IGF2R)

PHI:	102102551(IGF2R)

PMAJ:

107202068(IGF2R)

CCAE:

111927698(IGF2R)

CCW:	104693910(IGF2R)

CBRC:

103619439(IGF2R)

ETL:	114059582(IGF2R)

ZAB:	102069348(IGF2R)

ACHL:

103801394(IGF2R)

SVG:	106851870(IGF2R)

MMEA:

130572612(IGF2R)

HRT:	120749919(IGF2R)

FPG:	101917494(IGF2R)

FCH:	102047541(IGF2R)

CLV:	102086857(IGF2R)

EGZ:	104124820(IGF2R)

NNI:	104013809(IGF2R)

PCRI:

104023760(IGF2R)

EHS:	104514671(IGF2R)

PCAO:

104045370(IGF2R)

ACUN:

113477879(IGF2R)

TALA:

104360058(IGF2R)

PADL:

103918341(IGF2R)

AFOR:

103907843(IGF2R)

ACHC:

115344487(IGF2R)

HALD:

104317645(IGF2R)

HLE:	104842283(IGF2R)

AGEN:

126039042

GCL:

127013977

CCRI:

104161831(IGF2R)

CSTI:

104554218(IGF2R)

CMAC:

104481507(IGF2R)

MUI:	104547775(IGF2R)

BREG:

104637354(IGF2R)

FGA:	104075561(IGF2R)

GSTE:

104257293(IGF2R)

LDI:	104350778(IGF2R)

MNB:	103769305(IGF2R)

OHA:	104334713(IGF2R)

NNT:	104413757(IGF2R)

SHAB:

115613469(IGF2R)

DPUB:

104307731(IGF2R)

PGUU:

104469049(IGF2R)

ACAR:

104520734(IGF2R)

CPEA:

104390817(IGF2R)

AVIT:

104274032(IGF2R)

CVF:	104295754(IGF2R)

RTD:	128906550(IGF2R)

CUCA:

104056484(IGF2R)

TEO:	104384579(IGF2R)

BRHI:

104499201(IGF2R)

AAM:	106486768(IGF2R)

AROW:

112966407(IGF2R)

NPD:	112951952(IGF2R)

TGT:	104578197(IGF2R)

DNE:	112988998(IGF2R)

SCAM:

104152830(IGF2R)

ASN:	102382873(IGF2R)

AMJ:	102561234(IGF2R)

CPOO:

109320066(IGF2R)

GGN:	109304301(IGF2R)

PSS:	102451077(IGF2R)

CMY:	102937133(IGF2R)

CCAY:

125633989(IGF2R)

DCC:	119853102(IGF2R)

CPIC:

101944771(IGF2R)

TST:	117874787(IGF2R)

CABI:

116832453(IGF2R)

MRV:	120400859(IGF2R)

ACS:	100560621(igf2r)

ASAO:

132761104(IGF2R)

PVT:	110087416(IGF2R)

SUND:

121928273(IGF2R)

PBI:	103064868(IGF2R)

PMUR:

107292065 107297935

CTIG:

120314789(IGF2R)

TSR:	106548796(IGF2R)

PGUT:

117672078(IGF2R)

APRI:

131190861(IGF2R)

PTEX:

113439285(IGF2R)

NSS:	113417055(IGF2R)

VKO:

123026771

PMUA:

114594307(IGF2R)

PRAF:

128410717(IGF2R)

ZVI:	118081959(IGF2R)

HCG:	128344535(IGF2R)

GJA:	107111314(IGF2R)

STOW:

125428119(IGF2R)

EMC:	129323584(IGF2R)

XLA:	108716664(igf2r.L)

XTR:	496491(igf2r)

NPR:	108794547(IGF2R)

RTEM:

120937585(IGF2R)

BBUF:

120998701(IGF2R)

BGAR:

122933812(IGF2R)

MUO:	115466848(IGF2R)

GSH:	117356509(IGF2R)

DRE:	557061(igf2r)

SRX:	107727636 107743319

SANH:

107678818 107697131(igf2r)

SGH:	107549675 107603065

CCAR:

109044982 109100396 109107689

CAUA:

113114827 113120488

CGIB:

127938055 127983818

PTET:

122324640(igf2r)

LROH:

127182828(igf2r)

OMC:	131527145(igf2r)

PPRM:

120493802 120493804

RKG:	130103299(igf2r)

MAMB:

125278400(igf2r)

CIDE:

127502758

MASI:

127410022 127415590

TROS:

130565697(igf2r)

TDW:	130434187(igf2r)

MANU:

129429152(igf2r)

IPU:

100304998

IFU:	128600865(igf2r)

PHYP:

113531919(igf2r)

SMEO:

124377061(igf2r)

TFD:	113648305(igf2r)

TVC:	132843091(igf2r)

AMEX:

103037532(igf2r)

CMAO:

118815740(igf2r)

EEE:	113570044(igf2r)

CHAR:

105894851(igf2r)

TRU:	101076434(igf2r)

TFS:	130515822(igf2r)

TNG:	GSTEN00018498G001 GSTEN00018499G001

LCO:	104934231(igf2r)

TBEN:

117475065(igf2r)

CGOB:

115003887(igf2r)

PGEO:

117439736(igf2r)

GACU:

117533997

EMAC:

134876840(igf2r)

ELY:	117270365(igf2r)

EFO:	125896633(igf2r)

PLEP:

121955246(igf2r)

SLUC:

116060332(igf2r)

ECRA:

117961183(igf2r)

ESP:	116706008(igf2r)

PFLV:

114572918(igf2r)

GAT:	120807803(igf2r)

PPUG:

119194649(igf2r)

AFB:	129106802(igf2r)

CLUM:

117727195(igf2r)

PSWI:

130202299(igf2r)

MSAM:

119909163(igf2r)

SCHU:

122862999(igf2r)

CUD:	121520907(igf2r)

ALAT:

119012098(igf2r)

MZE:	101469073(igf2r)

ONL:	100703210(igf2r)

OAU:	116333119(igf2r)

OLA:	101173997(igf2r)

OML:	112141005(igf2r)

CSAI:

133418660(igf2r)

XMA:	102226253(igf2r)

XCO:	114158495(igf2r)

XHE:	116733862(igf2r)

PRET:

103457232(igf2r)

PFOR:

103129229(igf2r)

PLAI:

106949241(igf2r)

PMEI:

106917223(igf2r)

GAF:	122825214(igf2r)

PPRL:

129375265(igf2r)

CVG:	107083508(igf2r)

CTUL:

119795888

GMU:	124881812(igf2r)

NFU:	107377842(igf2r)

KMR:	108250280(igf2r)

ALIM:

106536326(igf2r)

NWH:	119418632(igf2r)

AOCE:

111565456(igf2r)

CSEM:

103381259(igf2r)

POV:	109639961 109645427(igf2r)

SSEN:

122783887(igf2r)

HHIP:

117758051(igf2r)

HSP:	118099222(igf2r)

SMAU:

118289832(igf2r)

LCF:

108890448

SDU:	111236260(igf2r)

SLAL:

111672612(igf2r)

XGL:	120788843(igf2r)

HCQ:	109523491(igf2r)

SSCV:

125990551

SBIA:

133496538(igf2r)

PEE:	133417314(igf2r)

PTAO:

133468199(igf2r)

BPEC:

110156231(igf2r)

MALB:

109970582(igf2r)

BSPL:

114849355(igf2r)

SJO:	128377480(igf2r)

SASA:

106571395 106607799

STRU:

115174818 115192936

OTW:	112217337(igf2r) 112250160

OMY:	110522220(igf2r) 110529599

OGO:	123990742 123995079

ONE:	115107742 115139425

OKI:	109866144 109900736

OKE:	118386887(igf2r) 118398668

SALP:

111954195 111972673

SNH:	120019294 120024337

CCLU:

121548934 121552795

ELS:	105017707(igf2r)

SFM:	108928531(igf2r)

PKI:	111836154(igf2r)

AANG:

118229749(igf2r)

LOC:	102690853(igf2r)

PSPA:

121317029(igf2r)

ARUT:

117411118(igf2r)

PSEX:

120516266(igf2r)

LCM:	102366185(IGF2R)

CMK:	103175955(igf2r)

RTP:

109934260

CPLA:

122552968(igf2r)

HOC:	132819824(igf2r)

LERI:

129699544(igf2r)

BFO:

BBEL:

CIN:

SPU:

LPIC:

APLC:

SKO:

DME:	Dmel_CG31072(Lerp)

DER:

6555255

DSE:

6617089

DSI:	Dsimw501_GD18117(Dsim_GD18117)

DYA:	Dyak_GE10613

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DMO:	Dmoj_GI10605

DAZ:

108621056

DNV:

108652265

DHE:

111600621

BDR:	105222101 125776600

RZE:

AOQ:

TDA:

LCQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ008495

CPII:

AME:

ADR:

BIM:

BTER:

BAFF:

FVI:

CCAL:

OBB:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

LHU:

PGC:

OBO:

PCF:

VCRB:

VVE:

NVI:	100679106 103318134

MDL:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

PPYR:

OTU:

API:

AGS:

RMD:

TPAL:

ZNE:	110835240 110835241

CSEC:

SGRE:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:

SDM:	118181863 118195571 118201919

LPOL:

106465466

HRO:	HELRODRAFT_193567

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:	111100622 111100629

CANU:

OED:

MYI:

PMAX:

MMER:

RPHI:

DPOL:

OBI:

OSN:

LAK:

NVE:

EPA:	110231992 110252925

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:	114534207 114534998

XEN:

124441653

HMG:

101241409

TAD:	TRIADDRAFT_60938 TRIADDRAFT_60939 TRIADDRAFT_64307

AQU:

100631698

MBR:	MONBRDRAFT_35769 MONBRDRAFT_36765

SRE:	PTSG_04871 PTSG_09952 PTSG_11512

DPP:	DICPUDRAFT_77883

DFA:

DFA_09727

» show all

Reference

PMID:2957598

Authors

Morgan DO, Edman JC, Standring DN, Fried VA, Smith MC, Roth RA, Rutter WJ

Title

Insulin-like growth factor II receptor as a multifunctional binding protein.

Journal

Nature 329:301-7 (1987)
DOI:10.1038/329301a0

Sequence

[hsa:3482]

Reference

PMID:10900005

Authors

Ikushima H, Munakata Y, Ishii T, Iwata S, Terashima M, Tanaka H, Schlossman SF, Morimoto C

Title

Internalization of CD26 by mannose 6-phosphate/insulin-like growth factor II receptor contributes to T cell activation.

Journal

Proc Natl Acad Sci U S A 97:8439-44 (2000)
DOI:10.1073/pnas.97.15.8439

Sequence

[hsa:3482]

LinkDB

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