KEGG   ORTHOLOGY: K07215
Entry
K07215                      KO                                     
Symbol
pigA, hemO
Name
heme oxygenase (biliverdin-IX-beta and delta-forming) [EC:1.14.99.58]
Pathway
map00860  Porphyrin metabolism
map01110  Biosynthesis of secondary metabolites
Reaction
R11816  protoheme,donor:oxygen oxidoreductase (biliverdin-IX-delta-forming)
R11817  protoheme,donor:oxygen oxidoreductase (biliverdin-IX-beta-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    K07215  pigA, hemO; heme oxygenase (biliverdin-IX-beta and delta-forming)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.99  Miscellaneous
    1.14.99.58  heme oxygenase (biliverdin-IX-beta and delta-forming)
     K07215  pigA, hemO; heme oxygenase (biliverdin-IX-beta and delta-forming)
Other DBs
COG: COG3230
Genes
XSA: SB85_17620
XHY: FZ025_13240
XEU: XSP_001726
SML: Smlt3896(pigA)
SMT: Smal_3312
BUJ: BurJV3_3345
SMZ: SMD_3498(hemO)
SRH: BAY15_3051
SLM: BIZ42_06025
STEN: CCR98_17210
STEM: CLM74_17440
STES: MG068_17095
SINC: DAIF1_34300
SPAQ: STNY_R35230
STEQ: ICJ04_09005
SGEN: RKE57_17275
LEZ: GLE_2425 GLE_2544
LEM: LEN_2561 LEN_2625
LAUX: LA521A_33560
LYA: RDV84_19650 RDV84_20200
LANH: KR767_13820
PAE: PA0672(hemO)
PAEV: N297_691
PAEI: N296_691
PAU: PA14_55580(nemO)
PAP: PSPA7_4838
PAG: PLES_46571(hemO)
PAF: PAM18_4366(hemO)
PNC: NCGM2_1335(nemO)
PAEB: NCGM1900_2097(nemO)
PDK: PADK2_22290
PSG: G655_22000
PRP: M062_03300
PAEP: PA1S_23245
PAER: PA1R_gp4177
PAEM: U769_23030
PAEL: T223_23770
PAES: SCV20265_4845
PAEG: AI22_10820
PAEC: M802_689
PAEO: M801_691
PMY: Pmen_4507
PFUW: KF707C_14810
PCQ: PcP3B5_29520
PMUI: G4G71_18140
PNT: G5B91_13845
PPAA: B7D75_21930
PPU: PP_1005(hemO) PP_2582
PPF: Pput_1042 Pput_3134
PPG: PputGB1_1004 PputGB1_3270
PPW: PputW619_4219
PPT: PPS_1032
PPB: PPUBIRD1_1055(hemO) PPUBIRD1_3098
PPI: YSA_00401 YSA_07091
PPX: T1E_1982 T1E_3329
PPUH: B479_05305
PPUT: L483_04875 L483_10345
PPUN: PP4_32840 PP4_43110(hemO)
PPUD: DW66_0993 DW66_1318
PFV: Psefu_1485
PMON: X969_03390
PMOT: X970_03365
PPJ: RK21_03967
PMOL: CLJ08_18050
PALD: LU682_005335 LU682_017715
PIX: RIN61_16770
PMOS: O165_017930
PST: PSPTO_1283
PSB: Psyr_1104
PSYR: N018_20130
PSP: PSPPH_1172
PSAV: PSA3335_09380
PAMG: BKM19_008375
PCI: PCH70_10510 PCH70_20260
PAVL: BKM03_07220
PCAB: JGS08_19320
PSYI: MME58_05480
PAST: N015_06200
PLIJ: KQP88_05040
PFL: PFL_4628(hemO)
PPRC: PFLCHA0_c47030
PPRO: PPC_4730(hemO)
PFE: PSF113_1273(hemO)
PFN: HZ99_10895
PFO: Pfl01_4380(hemO)
PFS: PFLU_4969
PFC: PflA506_4278(hemO)
PPZ: H045_15710
PFB: VO64_1844
PTV: AA957_20020
PCG: AXG94_21965
PVR: PverR02_25185
PAZO: AYR47_00755
POI: BOP93_20860
PRX: HRH33_21735
PMED: E3Z27_06370
PKR: AYO71_23850
PMUD: NCTC8068_04143(hemO)
PTOL: I7845_23360
PFW: PF1751_v1c44610(hemO)
PFF: PFLUOLIPICF713755
PFX: A7318_22425
PEN: PSEEN4423
PBA: PSEBR_a1203
PPUU: PputUW4_04268
PDR: H681_11250
PSV: PVLB_20140
PSK: U771_25760
PKC: PKB_3153
PCH: EY04_23460
PCZ: PCL1606_15510
PCP: JM49_07775
PCHP: C4K32_4815
PFZ: AV641_17525
PLQ: AA042_16210
PALK: PSAKL28_42420
PRH: LT40_03225
PSW: LK03_10315 LK03_11565
PPV: NJ69_01580
PSES: PSCI_0686
PSEM: TO66_24120
PSEC: CCOS191_1010
PPSY: AOC04_14775
PSOS: POS17_4695(hemO)
PFK: PFAS1_04850
PANR: A7J50_4738
PSET: THL1_4048
PSIL: PMA3_23130
PYM: AK972_1054
PKE: DLD99_22110
PUM: HGP31_06470
POJ: PtoMrB4_00820(hemO)
PGG: FX982_00647
PPSH: G5J76_21250
PGY: AWU82_25895
PVK: EPZ47_06570
PEZ: HWQ56_05285
PBZ: GN234_11880
PKH: JLK41_24760
PTY: JWV26_09495
PATA: JWU58_07080
PDW: BV82_0378
PZE: HU754_023120
PMOE: HV782_022370
PSEP: C4K39_3250
PPII: QL104_24035
PVW: HU752_007300
PTRT: HU722_0023710
PXA: KSS93_13130 KSS93_24240
PSAM: HU731_010070
PTZ: HU718_023705
PQI: KH389_05255 KH389_15085
PSHH: HU773_021825
PXN: HU772_019825
PHV: HU739_022570
PPRG: HU725_018195
PANH: HU763_005055 HU763_014315
PASG: KSS96_23100
PFAK: KSS94_10545 KSS94_21705
PMUY: KSS95_22610
PMAM: KSS90_05505
PAZE: KSS91_22855
PALV: KSS97_22510
PORY: EJA05_22540
PTK: EXN22_06670
PTW: TUM18999_00740(hemO)
PZA: HU749_007580
PIE: HU724_021850
PWY: HU734_020750
PTAE: NCTC10697_03378(hemO)
PGF: J0G10_24125
PJU: L1P09_04625 L1P09_10295
PHF: NLY38_24850
PPEG: KUA23_24385
PSII: NF676_20790
PSIH: LOY51_21420
PCAS: LOY40_22360
PFIT: KJY40_23500
PASI: LG197_10355
PKM: PZ739_04970 PZ739_17190
PNB: NK667_02380
PSOA: PSm6_20910(hemO) PSm6_52470
PTAI: ICN73_01375 ICN73_17540
PKK: QQ992_05310 QQ992_10365
PKJ: Q1W70_16645
PHYG: JTY93_20660
PHOM: KJF94_20035
PCHE: QYM18_07185
PTRL: OU419_12485
PPAE: LDL65_05405
PPAO: K3169_06995 K3169_08410
PRHZ: CRX69_04535
PSJY: AA098_11550 AA098_22405
PSKU: KUIN1_11480
PBB: AKN87_11790
PDEN: F1C79_05425
PSYY: DLE54_11750
ABM: ABSDF2281(hemO)
ABC: ACICU_00879
ABN: AB57_0991
ABZ: ABZJ_01018
ABD: ABTW07_1008
ABH: M3Q_1216
ABAB: BJAB0715_01031
ABAJ: BJAB0868_01027
ABAZ: P795_13120
ABAU: IX87_00955
ABW: BL01_11290
ABAL: ABLAC_16840
ACC: BDGL_000195
ALC: OTEC02_14295
ACAL: BUM88_04400
ACD: AOLE_14770
ACI: ACIAD1478(hemO)
AHL: AHTJS_08015
ALA: BFG52_00735 BFG52_05350
AGU: AS4_16540(hemO) AS4_29790(hemO) AS4_34070(hemO)
AUG: URS_0079
ADS: FPL17_05105 FPL17_05520
ABER: BSR55_05600 BSR55_05875
ACHI: CDG60_06315
AGYL: FPL18_16445 FPL18_16545
APRL: PY247_16635 PY247_16755
ACOI: NQU59_13010
AVIV: LF296_08975
MCT: MCR_0810
MCS: DR90_1063(hemO)
MCAT: MC25239_00820
MBL: AAX09_00735
MBOI: DQF64_13645
MCUN: NCTC10297_01679
MNN: I6G26_01995
MNC: LU297_04350
MNJ: LU290_00775
PPHE: PP2015_1080
PLZ: S4054249_20430
PPIS: B1L02_11525 B1L02_16525
PSPO: PSPO_b1580(hemO)
PSEN: PNC201_02230 PNC201_05320
PFLI: CTT31_05400 CTT31_16020
PMAZ: R5H13_05835 R5H13_16635
CJA: CJA_2682
CEB: B0D95_05540
MII: BTJ40_08780
MICT: FIU95_12695
MEJ: Q7A_2860
MMAF: GCM100_16120
MTHA: VSX76_02130
HASO: B2G49_15775
HAA: A5892_17145
ALCA: ASALC70_00415
ADI: B5T_01379 B5T_02871
AXE: P40_13405
MMW: Mmwyl1_0316
MME: Marme_4121
MPC: Mar181_0189
MARD: IBG28_01340
IGN: MMG00_06060
NME: NMB1669
NMP: NMBB_1917
NMH: NMBH4476_0553
NMD: NMBG2136_1544
NMM: NMBM01240149_0515
NMS: NMBM01240355_1595
NMQ: NMBM04240196_0563
NMZ: NMBNZ0533_1647
NMA: NMA1927
NMW: NMAA_1385(hemO)
NMX: NMA510612_2169(hemO)
NMC: NMC1587(hemO)
NMN: NMCC_1580(hemO)
NMT: NMV_0703(hemO)
NMI: NMO_1487(hemO)
NGO: NGO_1318
NGK: NGK_1541
NLA: NLA_6120(hemO)
NEL: NELON_05705
NWE: SAMEA3174300_0465
NSI: A6J88_13575
NMJ: NM96_08000
NEK: CGZ77_06420
NFV: FAH67_06335
NSF: FAH66_02655 FAH66_06430
NZL: D0T92_05755
NBL: GJV52_03840
NZO: SAMEA4504057_2176
NCI: NCTC10296_02432
NCZ: NCTC10294_01133
NANI: NCTC12227_01215
NBC: H3L91_03775
NWD: H3L96_08060
NSG: H3L94_03050
NSC: J7445_07380
NPF: LPB400_05550 LPB400_09265
NWX: CGZ65_02705
NDU: LVJ88_10020
NMB: MON40_10305
NLS: PJU73_02980
KKI: KKKWG1_0557
KOA: H3L93_08360
KPOT: LVJ84_03100
ECOR: SAMEA4412678_1893
EEX: EZJ17_05465
SMUR: BWP33_11515
AFF: H3L97_00895
ACRS: LVJ80_02295
CSTE: H3L98_02180
CKH: LVJ77_07805
MCER: MON37_02525
USU: LVJ78_08585
UTE: LVJ83_06310
WBO: MIS45_01425
CVC: BKX93_16175
CHRO: CXB49_19200
CHRI: DK842_10100
CHRB: DK843_15675
CRZ: D1345_01655
CHAE: CH06BL_03200(hemO)
AMAH: DLM_2969
VOG: LCH97_12965
IFL: C1H71_03065
PLG: NCTC10937_01155
BGM: CAL15_14005
BOJ: CBF45_11590
AXY: AXYL_01362
APES: FOC84_05880
ODI: ODI_R0759 ODI_R2515
PIG: EGT29_11135
KGY: EHF36_11845
CTES: O987_09790
KIA: G8A07_22425
JAB: VN23_02205
JAZ: YQ44_08140
JAL: BZG29_19635
JLV: G3257_20350
JRI: P9875_20220
HSE: Hsero_4544(hemO)
HSZ: ACP92_22685
HRB: Hrubri_4500(hemO)
HHF: E2K99_23910
HFR: G5S34_23825
CHEA: PVE73_20985
KMN: HW532_13095
ATU: Atu2502(hemO)
ATA: AWN88_17380
AGR: AGROH133_08500(hemO)
ATF: Ach5_23710(hemO)
AGT: EYD00_10565
ALF: CFBP5473_19205
ARUI: G6M88_18350
AVQ: HRR99_19225
ASAL: CFBP5507_11230
RIR: BN877_I2583(hemO)
RPUS: CFBP5875_10900
ACUC: KZ699_10935
ALEG: CFBP4996_10880
RHV: BA939_06940
ROY: G3A56_13445
ARO: B0909_00425
NGL: RG1141_CH36740
NGG: RG540_CH37350
NEO: CYG48_13935
NEN: NCHU2750_34870(hemO)
NPM: QEO92_05670
KAI: K32_07540(hemO)
OCH: CES85_5409
OCR: HGK82_15960
OCL: GTN27_21550
RPA: TX73_016950
RPT: Rpal_3698
TALZ: RPMA_17980
XAU: Xaut_2445
XDI: EZH22_25325
AZC: AZC_2040
STAR: G3545_20855
ANC: GBB76_12460
APRA: G3A50_18995
APOL: K9D25_01935
CHEL: AL346_23685
HDN: Hden_2796
BVR: BVIR_2196
BLAG: BLTE_19160(hemO)
CMET: K6K41_11325
AALM: LUX29_07170
PSIN: CAK95_10855
TSO: IZ6_19880(hemO)
PPHR: APZ00_02340
CMB: CSW64_11315
CFH: C1707_17175 C1707_22070
BRD: JL11_13400
BVC: CEP68_01790
BMED: GYM46_14985
BND: KWG56_03335
ASTI: Q1W73_16930
CID: P73_1096
RBL: B6K69_08870
PAEZ: PAE61_08110
PALS: PAF20_00405
DAA: AKL17_1133
PBAE: P8S53_18095
NRE: BES08_18035
NOV: TQ38_020470 TQ38_022580
SPHK: SKP52_21700
STAX: MC45_16995
SPHI: TS85_04935
SPLK: AV944_07335
SPAU: DRN02_000670
SECH: B18_15010
SMOR: LHA26_04060
SHAN: PPZ50_13265
SBD: ATN00_02120
SYA: A6768_11045 A6768_19435
SCLO: SCLO_1003440
SPHY: CHN51_07370
SPZR: G5C33_04240
POQ: KZX46_14920
GOH: B932_3435
GOY: GLS_c23040
GTI: FXF46_10960
GFA: MKW11_10765
GBE: GbCGDNIH1_0284
GBH: GbCGDNIH2_0284
GBC: GbCGDNIH3_0284
GBS: GbCGDNIH4_0284
GXL: H845_716
KSC: CD178_02487
APT: APA01_14070
APF: APA03_14070
APU: APA07_14070
APG: APA12_14070
APQ: APA22_14070
APX: APA26_14070
APZ: APA32_14070
APK: APA386B_225(pigA)
ASZ: ASN_1866(pigA)
ASV: WG31_07280
APER: A0U91_14455
APOM: CPF11_00660
ATO: CIW82_02685
ACET: DS739_07005
COQ: D9V35_01370
COMM: GN303_01565
TXI: TH3_20460
THAC: CSC3H3_19985
TLU: R1T41_08105
PARH: I5S86_23800
CHYA: V22_03740
 » show all
Reference
PMID:15122889
  Authors
Friedman J, Lad L, Li H, Wilks A, Poulos TL
  Title
Structural basis for novel delta-regioselective heme oxygenation in the opportunistic pathogen Pseudomonas aeruginosa.
  Journal
Biochemistry 43:5239-45 (2004)
DOI:10.1021/bi049687g
  Sequence
[pae:PA0672]
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