KEGG ORTHOLOGY: K07837

ORTHOLOGY: K07837

Entry

K07837                      KO

Symbol

RAP2A

Name

Ras-related protein Rap-2A

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins
    K07837  RAP2A; Ras-related protein Rap-2A
GTP-binding proteins [BR:ko04031]
Small (monomeric) G-proteins
  Ras Family
   Rap [OT]
    K07837  RAP2A; Ras-related protein Rap-2A

Genes

HSA:	5911(RAP2A)

PTR:	452629(RAP2A)

PPS:	100982532(RAP2A)

GGO:	101144418(RAP2A)

PON:	100172918(RAP2A)

NLE:	100607216(RAP2A)

HMH:	116467395(RAP2A)

MCC:	697215(RAP2A)

MTHB:

126940221

MNI:	105477630(RAP2A)

CSAB:

103214693(RAP2A)

CATY:

105574466(RAP2A)

PANU:

101011527(RAP2A)

TGE:	112610910(RAP2A)

MLEU:

105532482(RAP2A)

RRO:	104681001(RAP2A)

RBB:	108516522(RAP2A)

TFN:	117063586(RAP2A)

PTEH:

111546575(RAP2A)

CANG:

105505945(RAP2A)

CJC:	100404091(RAP2A) 118154652 118154798

SBQ:

101029784

CIMI:

108305404(RAP2A)

MMUR:

105867196(RAP2A)

PCOQ:

105812796(RAP2A)

MMU:	76108(Rap2a)

MCAL:

110309215(Rap2a)

MPAH:

110325269(Rap2a)

RNO:	114560(Rap2a)

MCOC:

116084378(Rap2a)

ANU:	117705513(Rap2a)

MUN:	110553011(Rap2a)

CGE:

103161160

MAUA:

106021897(Rap2a)

PROB:

127230099(Rap2a)

PLEU:

114692479(Rap2a)

MORG:

121460636(Rap2a)

MFOT:

126506669

AAMP:

119800030(Rap2a)

NGI:	103726154(Rap2a)

HGL:	101714988(Rap2a) 101725684

CCAN:

109686355(Rap2a)

DORD:

105990571(Rap2a) 106002834

DSP:	122110140(Rap2a)

PLOP:

125348155(Rap2a) 125359910

NCAR:

124985820

OCU:

127492104

OPI:	101536055(RAP2A)

TUP:	102472460(RAP2A)

GVR:	103600143(RAP2A)

CFA:	476968(RAP2A)

CLUD:

112655886(RAP2A)

VVP:	112923790(RAP2A)

VLG:	121477079(RAP2A)

NPO:	129516609(RAP2A)

AML:	100475620(RAP2A)

UMR:	103657587(RAP2A)

UAH:	113251482(RAP2A)

UAR:	123801051(RAP2A)

ELK:

111147015

LLV:

125094766

MPUF:

101676375

MNP:	132002620(RAP2A)

MLK:	131813724(RAP2A)

NVS:	122907200(RAP2A)

ORO:	101375778(RAP2A)

EJU:	114215885(RAP2A)

ZCA:	113919620(RAP2A)

MLX:	118009284(RAP2A)

NSU:	110585812(RAP2A)

LWW:

102725802

FCA:	101099924(RAP2A)

PYU:	121037782(RAP2A)

PBG:	122484091(RAP2A)

PVIV:

125168399(RAP2A)

LRUF:

124513312

PTG:	102954529(RAP2A)

PPAD:

109264140(RAP2A)

PUC:

125934163

AJU:

106973688

HHV:	120220349(RAP2A)

BTA:	522707(RAP2A)

BOM:	102286037(RAP2A)

BIU:	109566920(RAP2A)

BBUB:

102414877(RAP2A)

BBIS:

104982180

CHX:	102189691(RAP2A)

OAS:	114116641(RAP2A)

BTAX:

128057783(RAP2A)

ODA:	120883322(RAP2A)

CCAD:

122447335(RAP2A)

MBEZ:

129556465(RAP2A)

SSC:	100155367(RAP2A)

CFR:	102512433(RAP2A)

CBAI:

105072667(RAP2A)

CDK:	105089220(RAP2A)

VPC:	102532538(RAP2A)

BMUS:

118884320(RAP2A)

LVE:	103090701(RAP2A)

OOR:	101290215(RAP2A)

DLE:	111176443(RAP2A)

PCAD:

102991885(RAP2A)

PSIU:

116743073(RAP2A)

NASI:

112396116(RAP2A)

ECB:	100060181(RAP2A)

EPZ:	103548419(RAP2A)

EAI:	106846196(RAP2A)

MYD:	102766477(RAP2A)

MMYO:

118650715(RAP2A)

MLF:	102421815(RAP2A)

PKL:	118729147(RAP2A)

EFUS:

103288268(RAP2A)

MNA:	107530163(RAP2A)

DRO:	112310710(RAP2A)

SHON:

118994806(RAP2A)

AJM:	119039667(RAP2A)

PDIC:

114508665(RAP2A)

PHAS:

123818877(RAP2A)

MMF:	118622893(RAP2A)

PPAM:

129080945(RAP2A)

HAI:	109372558(RAP2A)

RFQ:	117021623(RAP2A)

PGIG:

120582536(RAP2A)

PVP:	105309355(RAP2A)

RAY:	107499220(RAP2A)

MJV:	108385859(RAP2A)

TOD:	119259782(RAP2A)

SARA:

101546128

SETR:

126016373(RAP2A)

TMU:

101346775

ETF:	101642096(RAP2A)

DNM:	101432922(RAP2A)

MDO:	100026652(RAP2A)

GAS:	123242649(RAP2A)

SHR:	111720015(RAP2A)

AFZ:

127553388

PCW:	110192686(RAP2A)

OAA:	114814710(RAP2A)

GGA:	769797(RAP2A)

PCOC:

116240294(RAP2A)

CJO:	107308017(RAP2A)

TPAI:

128071597(RAP2A)

LMUT:

125687900(RAP2A)

NMEL:

110408039(RAP2A)

APLA:

101804168(RAP2A)

ACYG:

106031797(RAP2A)

CATA:

118253081(RAP2A)

AFUL:

116489753(RAP2A)

TGU:	100231424(RAP2A)

LSR:	110470558(RAP2A)

SCAN:

115484865(RAP2A)

PMOA:

120512294(RAP2A)

OTC:	121345975(RAP2A)

PRUF:

121359365(RAP2A)

FAB:	101821633(RAP2A)

OMA:	130252160(RAP2A)

PHI:	102104925(RAP2A)

CCAE:

111945036(RAP2A)

CCW:	104685972(RAP2A)

ETL:	114055825(RAP2A)

ZAB:

113460044

SVG:	106851445(RAP2A)

MMEA:

130573641(RAP2A)

HRT:	120748549(RAP2A)

EGZ:	104125261(RAP2A)

NNI:

104014416

TALA:

104368215(RAP2A)

PADL:

103924776(RAP2A)

ACHC:

115350713(RAP2A)

AGEN:

GCL:

CSTI:

MNB:

OHA:	104338616(RAP2A)

SHAB:

115603211(RAP2A)

DPUB:

104309072(RAP2A)

CPEA:

104396501

CVF:	104292362(RAP2A)

RTD:	128917255(RAP2A)

CUCA:

104057293(RAP2A)

AROW:

112962219(RAP2A)

TGT:

104578469

SCAM:

104139304

ASN:	102383752(RAP2A)

AMJ:	102559525(RAP2A)

CPOO:

109306379(RAP2A)

GGN:	109302378(RAP2A)

PSS:

102456947

CMY:	102948219(RAP2A)

CCAY:

125638243(RAP2A)

DCC:	119860300(RAP2A)

CPIC:

101948175(RAP2A)

TST:	117870844(RAP2A)

CABI:

116819586(RAP2A)

MRV:	120388003(RAP2A)

ACS:	100560313(rap2a)

ASAO:

132771442(RAP2A)

PVT:	110073846(RAP2A)

SUND:

121926032(RAP2A)

PBI:	103059417(RAP2A)

PMUR:

107299031(RAP2A)

CTIG:

120305599(RAP2A)

TSR:	106547415(RAP2A)

PGUT:

117665645(RAP2A)

APRI:

131200237(RAP2A)

PTEX:

113441360(RAP2A)

NSS:	113412978(RAP2A)

VKO:	123027238(RAP2A)

PMUA:

114596584(RAP2A)

PRAF:

128411958(RAP2A)

ZVI:	118085136(RAP2A)

HCG:	128350842(RAP2A)

GJA:	107123951(RAP2A)

STOW:

125431015

EMC:	129326014(RAP2A) 129329693

XLA:	100505442 380407(rap2a.S)

XTR:	619593(rap2a)

NPR:	108799606(RAP2A)

RTEM:

120926317(RAP2A)

BBUF:

120995846(RAP2A)

BGAR:

122931295(RAP2A)

MUO:	115469077(RAP2A)

GSH:	117362149(RAP2A)

DRE:	100003903(rap2ab) 100332969

SRX:	107730400 107734761 107744958 107747235 107752601

SANH:

107653667 107677848 107689514

SGH:	107549783 107555252 107559797

CCAR:

109053184 109082023 109093187

CAUA:

113044593 113053442 113100083 113108951

CGIB:

127948352 127965096 128012269 128019561

PTET:

122347480(rap2ab) 122351620

LROH:

127162071(rap2ab) 127171227

OMC:	131547265 131549574(rap2ab)

PPRM:

120459919 120460474(rap2ab) 120492621

RKG:	130090988(rap2ab)

MAMB:

125269742 125272797(rap2ab)

CIDE:

127519181 127519437

MASI:

127443856 127444970 127447280 127448167

TROS:

130553157(rap2ab) 130555451

TDW:	130412029(rap2ab) 130427584

MANU:

129445087(rap2ab) 129452043

IPU:

IFU:

PHYP:

SMEO:

TFD:

TVC:

AMEX:

CMAO:

EEE:

CHAR:

105907999 105911819(rap2ab)

TRU:	101063715(rap2a) 101080194

TFS:	130522112 130527641

TNG:	GSTEN00026108G001 GSTEN00027166G001

LCO:	104922683 104926639

NCC:	104941381 104947513(rap2a)

TBEN:

117481123 117499019

CGOB:

115019898 115026351

PGEO:

117456967 117459935 117466608

GACU:

117544307 117546931

EMAC:

134860982 134867294

ELY:	117249782 117251564

EFO:	125885093 125899641

PLEP:

121949358 121962671

SLUC:

116044647 116047843

ECRA:

117939585 117952853

ESP:	116673943 116698318(rap2a)

PFLV:

114551144 114563983

GAT:	120824698 120834489

PPUG:

119215526 119228555

AFB:	129104802 129111613

CLUM:

PSWI:

MSAM:

SCHU:

CUD:	121506275 121522932

ALAT:

119015539 119025463

MZE:	101474407 101474707

ONL:	100694930 100695037

OAU:	116319192 116323065

OLA:	101155833 101166017

OML:	112154900 112160095

CSAI:

133424877 133445911

XMA:	102231957 102232092

XCO:	114137620 114147801

XHE:	116716079 116722663

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122827204 122839649

PPRL:

129360960 129379016

CVG:	107093558 107093740

CTUL:

119781245 119793927

GMU:	124861655 124871194

NFU:	107381091 107389972

KMR:	108239803 108248772

ALIM:

106524665

NWH:	119419635 119428771

AOCE:

111569957 111582606

MCEP:

125001137 125017290

CSEM:

103389868 103391592

POV:	109631461 109645265 109647594

SSEN:

122763903 122765492

HHIP:

117755258 117776934

HSP:	118103299 118119659

SMAU:

118300953 118320531

LCF:	108872959 108881515

SDU:	111218451(rap2a) 111238715

SLAL:

111644452 111662158

XGL:	120798147 120801538

HCQ:	109520931 109523394

SSCV:

125973973 125988547

SBIA:

133491885 133511812

PEE:	133410546 133410843

PTAO:

133486921 133489504

BPEC:

110166291 110173112(rap2a)

MALB:

109955756 109958129(rap2a)

BSPL:

114847508 114851191

SJO:	128354409 128367870

SASA:

106575110 106582448 106586264

STRU:

115155505 115160805 115179276 115195218

OTW:	112237011 112252018 112254010

OMY:	110501909 110520154 110527579

OGO:	123991399 124008849 124043902

ONE:	115109557 115130551 115134437

OKI:	109867089 109871272 109890121

OKE:	118367028 118370128 118386394

SALP:

111975747 112071548

SNH:	120033572 120057886 120064121

CCLU:

121536749 121555080 121562373 123489675

ELS:	105024753(rap2a)

SFM:	108918110 108930370

PKI:	111834157(rap2a) 111859684

AANG:

118214230 118223896

LOC:	102697644(rap2a)

PSPA:

121320896 121328025

ARUT:

117406363 117407532

PSEX:

120523802

LCM:	102355823(RAP2A)

CMK:	103177969 103186995

RTP:

CPLA:

HOC:

LERI:

CIN:

SCLV:

GFS:

VDE:

BMY:	BM_BM17816(Bma-rap-2)

LOA:	LOAG_04856

TSP:

OED:

PDAM:

HMG:

AQU:

CHIG:

ABP:	AGABI1DRAFT114195(AGABI1DRAFT_114195)

SLA:	SERLADRAFT_390117

EIV:	EIN_062680

TBR:	Tb11.02.3850

TBG:	TbgDal_XI6780

» show all

Reference

PMID:10777494

Authors

de Rooij J, Rehmann H, van Triest M, Cool RH, Wittinghofer A, Bos JL

Title

Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs.

Journal

J Biol Chem 275:20829-36 (2000)
DOI:10.1074/jbc.M001113200

Sequence

[hsa:5911]

LinkDB

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