KEGG ORTHOLOGY: K08665

ORTHOLOGY: K08665

Entry

K08665                      KO

Symbol

HPN

Name

hepsin [EC:3.4.21.106]

Pathway

map05203

Viral carcinogenesis

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K08665  HPN; hepsin
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K08665  HPN; hepsin
Enzymes [BR:ko01000]
3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.106  hepsin
     K08665  HPN; hepsin
Peptidases and inhibitors [BR:ko01002]
Serine peptidases
  Family S1: chymotrypsin family
   K08665  HPN; hepsin

Genes

HSA:

3249(HPN)

PTR:	455944(HPN)

PPS:	100987098(HPN)

GGO:	101135897(HPN)

PON:	100173788(HPN)

NLE:	100591395(HPN)

HMH:	116478890(HPN)

MCC:	707242(HPN)

MCF:	102120705(HPN)

MTHB:

126941908

MNI:	105495546(HPN)

CSAB:

103234489(HPN)

CATY:

105578154(HPN)

PANU:

101024426(HPN)

TGE:	112612344(HPN)

MLEU:

105541322(HPN)

RRO:	104667121(HPN)

RBB:	108512302(HPN)

TFN:	117092331(HPN)

PTEH:

113219585

CANG:

105515772(HPN)

CJC:	100401729(HPN)

SBQ:	101040717(HPN)

CIMI:

108286383(HPN)

CSYR:

103271110(HPN)

MMUR:

105876945(HPN)

LCAT:

123624496(HPN)

PCOQ:

105816229(HPN) 105816957

OGA:	100944961(HPN)

MMU:	15451(Hpn)

MCAL:

110297696(Hpn)

MPAH:

110330287(Hpn)

RNO:	29135(Hpn)

MCOC:

116101186(Hpn)

ANU:	117716206(Hpn)

MUN:	110551185(Hpn)

CGE:	100757163(Hpn)

MAUA:

101832050(Hpn)

PROB:

127238640(Hpn)

PLEU:

114698928(Hpn)

MORG:

121449413(Hpn)

MFOT:

126486649

AAMP:

119820441(Hpn)

NGI:	103729906(Hpn)

HGL:	101708013(Hpn)

CPOC:

100719031(Hpn)

CCAN:

109694561(Hpn)

DORD:

105993093(Hpn)

DSP:	122097496(Hpn)

PLOP:

125338780(Hpn)

NCAR:

124966370

MMMA:

107151680(Hpn)

OCU:

100345382

OPI:	101535144(HPN)

TUP:	102472167(HPN)

GVR:	103596678(HPN)

CFA:	484583(HPN)

CLUD:

112643575(HPN)

VVP:	112928515(HPN)

VLG:	121484104(HPN)

NPO:	129500635(HPN)

AML:	100473121(HPN)

UMR:	103682491(HPN)

UAH:	113244804(HPN)

UAR:	123791724(HPN)

ELK:

111161519

LLV:

125088420

MPUF:

101674851(HPN)

MNP:	132005625(HPN)

MLK:	131817363(HPN)

NVS:	122911538(HPN)

ORO:	101374485(HPN)

EJU:	114224384(HPN)

ZCA:	113935608(HPN)

MLX:	118022823(HPN)

NSU:	110590118(HPN)

LWW:	102738257(HPN)

FCA:	101099007(HPN)

PYU:	121011591(HPN)

PCOO:

112851260(HPN)

PBG:	122495012(HPN)

PVIV:

125153565(HPN)

LRUF:

124511761

PTG:	102961568(HPN)

PPAD:

109251456(HPN)

PUC:	125918023 125918520

AJU:

106974756

HHV:	120226193(HPN)

BTA:	508148(HPN)

BOM:	102265892(HPN)

BIU:	109572366(HPN)

BBUB:

102415384(HPN)

BBIS:

104995409(HPN)

CHX:	102188889(HPN)

OAS:	101117692(HPN)

BTAX:

128063691(HPN)

ODA:	120872538(HPN)

CCAD:

122421422(HPN)

MBEZ:

129546099(HPN)

SSC:	100624088(HPN)

CFR:	102522484(HPN)

CBAI:

105065097(HPN)

CDK:	105088028(HPN)

VPC:	102536793(HPN)

BACU:

103014212(HPN)

BMUS:

118884852(HPN)

LVE:	103089245(HPN)

OOR:	101279617(HPN)

DLE:	111181162(HPN)

PCAD:

102995164(HPN)

PSIU:

116744599(HPN)

NASI:

112392267(HPN)

ECB:	100058873(HPN)

EPZ:	103547718(HPN)

EAI:	106829219(HPN)

MYB:	102254751(HPN)

MYD:	102771439(HPN)

MMYO:

118674541(HPN)

MLF:	102435620(HPN)

PKL:	118720817(HPN)

EFUS:

103284489(HPN)

MNA:	107543422(HPN)

DRO:	112320092(HPN)

SHON:

118982509(HPN)

AJM:	119037343(HPN)

PDIC:

114511573(HPN)

PHAS:

123823824(HPN)

MMF:	118638623(HPN)

PPAM:

129083184(HPN)

HAI:	109372038(HPN)

RFQ:	117034958(HPN)

PALE:

102898712(HPN)

PGIG:

120592437(HPN)

PVP:	105306622(HPN)

RAY:	107504252(HPN)

MJV:	108398953(HPN)

TOD:	119250196(HPN)

SARA:

101546934(HPN)

SETR:

126027695(HPN)

LAV:	100673906(HPN)

TMU:

101353096

ETF:	101652789(HPN)

DNM:	101419719(HPN)

MDO:	100015125(HPN)

GAS:	123240062(HPN)

SHR:	100924033(HPN)

AFZ:

127556115

PCW:	110201622(HPN)

OAA:	107547747(HPN)

ASN:	102385148(HPN)

AMJ:	102570449(HPN)

PSS:	102443380(HPN)

CMY:	102934816(HPN)

CCAY:

125626160(HPN)

DCC:	119847877(HPN)

CPIC:

101951444(HPN)

TST:	117869689(HPN)

CABI:

116829844(HPN)

MRV:	120390042(HPN)

ACS:	100553659(hpn)

ASAO:

132780227(HPN)

PVT:	110070730(HPN)

SUND:

121915445(HPN)

PBI:	103059263(HPN)

PMUR:

107287563(HPN)

CTIG:

120300145(HPN)

TSR:

106556162

PGUT:

117669327(HPN)

APRI:

131204511(HPN)

PTEX:

113448230(HPN)

NSS:

113430619

VKO:	123019417(HPN)

PMUA:

114603542(HPN)

PRAF:

128418543(HPN)

ZVI:	118087370(HPN)

HCG:	128333366(HPN)

GJA:	107119876(HPN)

STOW:

125434214(HPN)

EMC:	129343248(HPN)

XLA:	108697289(hpn.S) 108705714

XTR:	100145343(hpn)

NPR:	108798671(HPN)

RTEM:

120916218(HPN)

BBUF:

120993612(HPN)

BGAR:

122929102(HPN)

MUO:	115476969(HPN)

GSH:	117369134(HPN)

DRE:	569259(hpn)

SRX:	107726693 107728492

SANH:

107665644 107666884(hpn)

SGH:

CCAR:

CAUA:

CGIB:

PTET:

122361098(hpn)

LROH:

127178395(hpn)

OMC:	131521702(hpn)

PPRM:

120488365 120488377

MAMB:

125243809(hpn)

CIDE:

127497428

MASI:

127453159 127453687

TROS:

130557438(hpn)

TDW:	130433310(hpn)

MANU:

129448647(hpn)

IPU:

108256296

IFU:	128599848(hpn)

PHYP:

113532956(hpn)

SMEO:

124375558(hpn)

TFD:	113649815(hpn)

TVC:	132840022(hpn)

AMEX:

103024311

CMAO:

118799184(hpn)

EEE:

113571958

CHAR:

105891945(hpn)

TRU:	101061536 101065267 101065721 105419034 105419796 115250346 115250347 115250348 115250351 115250352 115250354

TFS:	130519650 130520311 130520313 130520606 130520607 130532135 130532428 130532430

TNG:	GSTEN00035339G001

LCO:	104928115(hpn)

NCC:	104962735(hpn)

TBEN:

117480224(hpn)

CGOB:

115020873(hpn)

PGEO:

117461172(hpn)

GACU:

117540815(hpn)

EMAC:

134861499(hpn)

ELY:	117266518(hpn)

EFO:	125893309(hpn)

PLEP:

121946050(hpn)

SLUC:

116035244(hpn)

ECRA:

117946121(hpn)

ESP:	116690948(hpn)

PFLV:

114557880(hpn)

GAT:	120810983(hpn)

PPUG:

119197556(hpn)

AFB:	129109115(hpn)

CLUM:

117745121(hpn)

PSWI:

130212844(hpn)

MSAM:

119897955(hpn)

SCHU:

122881015(hpn)

CUD:	121514033(hpn)

ALAT:

119006513(hpn)

MZE:	101473962(hpn)

ONL:	100700000(hpn)

OAU:	116314979(hpn)

OLA:	101171277(hpn)

OML:	112143879(hpn)

CSAI:

133426089(hpn)

XMA:	102234257(hpn)

XCO:	114141601(hpn)

XHE:	116717949(hpn)

PRET:

103478304(hpn)

PFOR:

103139639(hpn)

PLAI:

106936844(hpn)

PMEI:

106907984(hpn)

GAF:	122831525(hpn)

PPRL:

129367638(hpn)

CVG:	107103338(hpn)

CTUL:

119786448(hpn)

GMU:	124866406(hpn)

NFU:	107378964(hpn)

KMR:	108232207(hpn)

ALIM:

106526042(hpn)

NWH:	119409584(hpn)

AOCE:

111572959(hpn)

MCEP:

125016055(hpn)

CSEM:

103388772(hpn)

POV:	109631942(hpn)

SSEN:

122775258(hpn)

HHIP:

117777537(hpn)

HSP:	118114279(hpn)

SMAU:

118316859(hpn)

LCF:

108888185

SDU:	111227890(hpn)

SLAL:

111658126(hpn)

XGL:	120784437(hpn)

HCQ:	109529638(hpn)

SSCV:

125974662

SBIA:

133500952(hpn)

PEE:	133401208(hpn)

PTAO:

133480007(hpn)

BPEC:

110171625

MALB:

109958531(hpn)

BSPL:

114843287(hpn)

SJO:	128366040(hpn)

SASA:

106577761 106605629

STRU:

115177452 115182642

OTW:	112227142 112245872

OMY:	110519917 110538566

OGO:	123997990 124005695

ONE:	115102104 115140887

OKI:	109900943 109901830

OKE:	118364602 118367645

SALP:

111958996 111964607

SNH:	120030840 120048547

CCLU:

121543056 121556065

ELS:	105019132(hpn)

SFM:	108919201(hpn)

PKI:	111838295(hpn)

AANG:

118224888(hpn)

LOC:	102686706(hpn)

PSPA:

121298869 121304226

ARUT:

117433772 117972151

PSEX:

120541725(hpn)

LCM:	102358874(HPN)

HOC:	132808779(hpn)

BFO:	118412369 118420750

SCLV:

AAG:

NMEA:

NVI:

BANY:

MCIX:

PPOT:

TNL:

DCI:

IEL:

HRO:	HELRODRAFT_170189

LGI:	LOTGIDRAFT_84942

HRF:

OSN:

NVE:

ATEN:

SPIS:

HSY:	130625394 130630615

MNG:

MNEG_2561

» show all

Reference

PMID:9395459

Authors

Vu TK, Liu RW, Haaksma CJ, Tomasek JJ, Howard EW

Title

Identification and cloning of the membrane-associated serine protease, hepsin, from mouse preimplantation embryos.

Journal

J Biol Chem 272:31315-20 (1997)
DOI:10.1074/jbc.272.50.31315

Sequence

[mmu:15451]

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