KEGG ORTHOLOGY: K08831

ORTHOLOGY: K08831

Entry

K08831                      KO

Symbol

SRPK2

Name

serine/threonine-protein kinase SRPK2 [EC:2.7.11.1]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K08831  SRPK2; serine/threonine-protein kinase SRPK2
  09182 Protein families: genetic information processing
   03041 Spliceosome
    K08831  SRPK2; serine/threonine-protein kinase SRPK2
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K08831  SRPK2; serine/threonine-protein kinase SRPK2
Protein kinases [BR:ko01001]
Serine/threonine kinases: CMGC group
  SRPK family [OT]
   K08831  SRPK2; serine/threonine-protein kinase SRPK2
Spliceosome [BR:ko03041]
Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    K08831  SRPK2; serine/threonine-protein kinase SRPK2

Genes

HSA:	6733(SRPK2)

PTR:	463641(SRPK2)

PPS:	100983375(SRPK2)

GGO:	101145331(SRPK2)

PON:	100447444(SRPK2)

NLE:	100591316(SRPK2)

HMH:	116814206(SRPK2)

MCC:	697351(SRPK2)

MCF:	101867513(SRPK2)

MTHB:

126949839

MNI:	105475333(SRPK2)

CSAB:

103226695(SRPK2)

CATY:

105583168(SRPK2)

PANU:

101010806(SRPK2)

TGE:	112621771(SRPK2)

MLEU:

105554093(SRPK2)

RRO:	104675875(SRPK2)

RBB:	108531293(SRPK2)

TFN:	117073231(SRPK2) 117083749

PTEH:

111526694(SRPK2)

CANG:

105501711(SRPK2)

CJC:	100390282(SRPK2)

SBQ:	101033421(SRPK2)

CIMI:

108287697(SRPK2)

CSYR:

103274302(SRPK2)

MMUR:

105861370(SRPK2)

LCAT:

123647294(SRPK2)

PCOQ:

105815199(SRPK2)

OGA:	100954239(SRPK2)

MMU:	20817(Srpk2)

MCAL:

110294016(Srpk2)

MPAH:

110313869(Srpk2)

RNO:	296753(Srpk2)

MCOC:

116097529(Srpk2)

ANU:	117720384(Srpk2)

MUN:	110552816(Srpk2)

CGE:	100759043(Srpk2)

MAUA:

101823933(Srpk2)

PROB:

127214404(Srpk2)

PLEU:

114681825(Srpk2)

MORG:

121459126(Srpk2)

MFOT:

126500119

AAMP:

119803798(Srpk2)

NGI:	103732192(Srpk2)

HGL:	101699614 101715406(Srpk2)

CPOC:

100726938(Srpk2)

CCAN:

109684279 109684283(Srpk2)

DORD:

105999649(Srpk2)

DSP:	122111782(Srpk2)

PLOP:

125346904(Srpk2)

NCAR:

124990997

MMMA:

107144558(Srpk2)

OCU:

100354102

OPI:	101520275(SRPK2)

TUP:	102484731(SRPK2)

GVR:	103586680(SRPK2)

CFA:	475894(SRPK2)

CLUD:

112661449(SRPK2)

VVP:	112925374(SRPK2)

VLG:	121501367(SRPK2)

NPO:	129494322(SRPK2)

AML:	100468643(SRPK2)

UMR:	103674647(SRPK2)

UAH:	113258812(SRPK2)

UAR:	123789384(SRPK2)

ELK:

111155212

LLV:

125081231

MPUF:

101687171(SRPK2)

MNP:	132016020(SRPK2)

MLK:	131829268(SRPK2)

NVS:	122904728(SRPK2)

ORO:	101362636(SRPK2)

EJU:	114221928(SRPK2)

ZCA:	113911902(SRPK2)

MLX:	118020646(SRPK2)

NSU:	110574279(SRPK2)

LWW:	102737279(SRPK2)

FCA:	101084692(SRPK2)

PYU:	121028859(SRPK2)

PCOO:

112866954(SRPK2)

PBG:	122487771(SRPK2)

PVIV:

125148019(SRPK2)

LRUF:

124524291

PTG:	102949409(SRPK2)

PPAD:

109268103(SRPK2)

PUC:

125930782

AJU:

106978475

HHV:	120243584(SRPK2)

BTA:	505945(SRPK2)

BOM:	102280798(SRPK2)

BIU:	109557368(SRPK2)

BBUB:

102400589(SRPK2)

BBIS:

104989724(SRPK2)

CHX:	102169250(SRPK2)

OAS:	101122186(SRPK2)

BTAX:

128047074(SRPK2)

ODA:	120878166(SRPK2)

CCAD:

122438293(SRPK2)

MBEZ:

129552376(SRPK2)

SSC:	100627848(SRPK2)

CFR:	102514978(SRPK2)

CBAI:

105062413(SRPK2)

CDK:	105093022(SRPK2)

VPC:	102536386(SRPK2)

BACU:

102997309(SRPK2)

BMUS:

118900470(SRPK2)

LVE:	103073745(SRPK2)

OOR:	101285130(SRPK2)

DLE:	111164614(SRPK2)

PCAD:

102981183(SRPK2)

PSIU:

116759806(SRPK2)

NASI:

112407430(SRPK2)

ECB:	100050379(SRPK2)

EPZ:	103560582(SRPK2)

EAI:	106825185(SRPK2)

MYB:	102245597(SRPK2)

MYD:	102758505(SRPK2)

MMYO:

118666016(SRPK2)

MLF:	102419571(SRPK2)

PKL:	118714394(SRPK2)

EFUS:

103293540(SRPK2)

MNA:	107542285(SRPK2)

DRO:	112303249(SRPK2)

SHON:

118994426(SRPK2)

AJM:	119063553(SRPK2)

PDIC:

114507248(SRPK2)

PHAS:

123811827(SRPK2)

MMF:	118620492(SRPK2)

PPAM:

129063070(SRPK2)

HAI:	109392053(SRPK2)

RFQ:	117012251(SRPK2)

PALE:

102887977(SRPK2)

PGIG:

120591656(SRPK2)

PVP:	105300339(SRPK2)

RAY:	107511502(SRPK2)

MJV:	108398625(SRPK2)

TOD:	119245076(SRPK2)

SARA:

101541314(SRPK2)

SETR:

126022827(SRPK2)

LAV:	100656100(SRPK2)

TMU:

101357145

ETF:	101663605(SRPK2)

DNM:	101441492(SRPK2)

MDO:	100018519(SRPK2)

GAS:	123249983(SRPK2)

SHR:	100923886(SRPK2)

AFZ:

127538134

PCW:	110206992(SRPK2)

OAA:	100077290(SRPK2)

GGA:	417711(SRPK2)

PCOC:

116230926(SRPK2)

MGP:	100545709(SRPK2)

CJO:	107325242(SRPK2)

TPAI:

128079559(SRPK2)

LMUT:

125692245(SRPK2)

NMEL:

110392364(SRPK2)

APLA:

101805474(SRPK2)

ACYG:

106043275(SRPK2)

CATA:

118249530(SRPK2)

AFUL:

116502299(SRPK2)

TGU:	100232158(SRPK2)

LSR:	110472727(SRPK2)

SCAN:

103813523(SRPK2)

PMOA:

120509270(SRPK2)

OTC:	121336376(SRPK2)

PRUF:

121357416(SRPK2)

GFR:	102037382(SRPK2)

FAB:	101809583(SRPK2)

OMA:	130265256(SRPK2)

PHI:	102108155(SRPK2)

PMAJ:

107204273(SRPK2)

CCAE:

111923253(SRPK2)

CCW:	104686926(SRPK2)

CBRC:

103623421(SRPK2)

ETL:	114060529(SRPK2)

ZAB:	102066999(SRPK2)

ACHL:

103800996(SRPK2)

SVG:	106848841(SRPK2)

MMEA:

130572665(SRPK2)

HRT:	120751472(SRPK2)

FPG:	101920088(SRPK2)

FCH:	102054236(SRPK2)

CLV:	102094023(SRPK2)

EGZ:	104128567(SRPK2)

NNI:	104010729(SRPK2)

PCRI:

104032672(SRPK2)

PLET:

104626409(SRPK2)

EHS:	104517000(SRPK2)

PCAO:

104051310(SRPK2)

ACUN:

113490174(SRPK2)

TALA:

104361765(SRPK2)

PADL:

103920579(SRPK2)

AFOR:

103906974(SRPK2)

ACHC:

115341063(SRPK2)

HALD:

104311005(SRPK2)

HLE:	104840155(SRPK2)

AGEN:

126044474

GCL:

127017616

CCRI:

104155358

CSTI:

104550977(SRPK2)

CMAC:

104487700(SRPK2)

MUI:	104535116(SRPK2)

BREG:

104641744(SRPK2)

FGA:	104080347(SRPK2)

GSTE:

104263975(SRPK2)

LDI:	104342955(SRPK2)

MNB:	103769375(SRPK2)

OHA:	104328749(SRPK2)

NNT:	104404434(SRPK2)

SHAB:

115605052(SRPK2)

DPUB:

104307865(SRPK2)

PGUU:

104463397(SRPK2)

ACAR:

104526130(SRPK2)

CPEA:

104394277(SRPK2)

CVF:	104285139(SRPK2)

RTD:	128904182(SRPK2)

CUCA:

104056099(SRPK2)

TEO:	104372892(SRPK2)

BRHI:

104490851(SRPK2)

AAM:	106485937(SRPK2)

AROW:

112962652(SRPK2)

NPD:	112953317(SRPK2)

TGT:	104570787(SRPK2)

DNE:	112981750(SRPK2)

SCAM:

104140581(SRPK2)

ASN:	102375401(SRPK2)

AMJ:	106736736(SRPK2)

CPOO:

109315735(SRPK2)

GGN:	109292147(SRPK2)

PSS:	102454350(SRPK2)

CMY:	102933816(SRPK2)

CCAY:

125630440(SRPK2)

DCC:	119855287(SRPK2)

CPIC:

101938318(SRPK2)

TST:	117875209(SRPK2)

CABI:

116828854(SRPK2)

MRV:	120392476(SRPK2)

ACS:	100560259(srpk2)

ASAO:

132776560(SRPK2)

PVT:	110080954(SRPK2)

SUND:

121930572(SRPK2)

PBI:	103052194(SRPK2)

CTIG:

120313001(SRPK2) 120313721

PGUT:

117675231(SRPK2)

APRI:

131201680(SRPK2)

PTEX:

113436859(SRPK2)

NSS:	113418374(SRPK2)

VKO:	123019962(SRPK2)

PMUA:

114605823(SRPK2)

PRAF:

128421618(SRPK2)

ZVI:	118090746(SRPK2)

HCG:	128327967(SRPK2)

GJA:	107113708(SRPK2)

STOW:

125435900(SRPK2)

EMC:	129335642(SRPK2)

XLA:	100329198(srpk3.S) 108711189

XTR:	100125041(srpk3)

NPR:	108795232(SRPK2)

RTEM:

120931761(SRPK2)

BBUF:

120982468(SRPK2)

BGAR:

122927873(SRPK2)

MUO:	115478557(SRPK2)

GSH:	117367291(SRPK2)

DRE:	100333293(srpk2)

SRX:	107716527 107756716

SANH:

107690103 107704204

SGH:	107552422 107574156

CCAR:

109078636 109113160

CAUA:

113067295

CGIB:

127947389

PTET:

122330512(srpk2) 122354336

LROH:

127156645(srpk2)

OMC:	131534037(srpk2)

PPRM:

120474030(srpk2)

RKG:	130070839(srpk2)

MAMB:

125261898(srpk2)

CIDE:

127524196

MASI:

127435733 127437610

TROS:

130549658(srpk2)

TDW:	130414640(srpk2)

MANU:

129434291(srpk2)

IPU:

108274687

IFU:	128617712(srpk2)

PHYP:

113529635

SMEO:

124391986(srpk2)

TFD:	113639130(srpk2)

TVC:	132856525(srpk2)

AMEX:

103046550(srpk2)

CMAO:

118811797(srpk2)

EEE:

113571831

TRU:

101063511

TFS:	130535841(srpk2)

LCO:

104931973

TBEN:

117497448

CGOB:

115009432

PGEO:

117447701(srpk2)

GACU:

117547817(srpk2)

EMAC:

134876073

ELY:	117261650(srpk2)

EFO:	125887491(srpk2)

PLEP:

121949817(srpk2)

SLUC:

116038750(srpk2)

ECRA:

117949605(srpk2)

ESP:

116693356

PFLV:

114559703

GAT:	120808605 120812332

PPUG:

119195731(srpk2)

AFB:	129107735(srpk2)

CLUM:

117731876(srpk2)

PSWI:

130194952

MSAM:

119893652(srpk2)

SCHU:

122875475(srpk2)

CUD:	121514732(srpk2)

ALAT:

119024044(srpk2)

MZE:

101478901

ONL:	100708071(srpk2)

OAU:	116333109(srpk2)

OLA:

101167956

OML:	112152021(srpk2)

CSAI:

133443827(srpk2)

XMA:

102225031

XCO:

114159633

XHE:	116737291(srpk2)

PRET:

103478812(srpk2)

PFOR:

103134474

PLAI:

106936343(srpk2)

PMEI:

106907745

GAF:	122836094(srpk2)

PPRL:

129365598(srpk2)

CVG:

107101350

CTUL:

119780388(srpk2)

GMU:	124860888(srpk2)

NFU:	107388435(srpk2)

KMR:

108248824

NWH:

119416508

AOCE:

111584327(srpk2)

MCEP:

125014393

CSEM:

103380327

POV:

109624312

SSEN:

122776031(srpk2)

HHIP:

117763733(srpk2)

HSP:	118109381(srpk2)

SMAU:

118315589(srpk2)

LCF:

108883082

SDU:	111229577(srpk2)

SLAL:

111650323(srpk2)

XGL:	120793253(srpk2)

HCQ:	109529861(srpk2)

SSCV:

125970895

SBIA:

133502424

PEE:	133403250(srpk2)

PTAO:

133478064(srpk2)

BPEC:

110169417

MALB:

109973402(srpk2)

BSPL:

114856769(srpk2)

SJO:	128359394(srpk2)

SASA:

106560984 106584470

STRU:

115192657 115196961

OTW:	112218165 112228569

OMY:	110493507 110521409(srpk2)

OGO:	124037645 124038429

ONE:	115134649 115144890

OKI:	109866918 109897832

OKE:	118359256 118396227

SALP:

111962228 111972073

SNH:	120052423 120066156

CCLU:

121531733 121540613

ELS:

105029402

SFM:	108931551 108935899(srpk2)

PKI:	111833271 111834167(srpk2)

AANG:

118219140 118231164

LOC:	102694947(srpk2)

PSPA:

121318980 121319161

ARUT:

117414719 117419800

PSEX:

120539611(srpk2)

LCM:	102351943(SRPK2)

CMK:	103176974 103179151

RTP:	109916979 109935030(srpk1a)

CPLA:

HOC:

LERI:

PMRN:

LRJ:	133349352(SRPK2) 133356458

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

AJC:

SKO:

DSR:

ZNE:

CSEC:

FCD:

TCF:

PPOI:

SDM:

PCAN:

BGT:

HRF:

CANU:

OED:

MYI:

PMAX:

OSN:

LAK:

SMM:	Smp_041770

OVI:	T265_05953

EGL:

XEN:

HMG:

Reference

PMID:19592491

Authors

Jang SW, Liu X, Fu H, Rees H, Yepes M, Levey A, Ye K

Title

Interaction of Akt-phosphorylated SRPK2 with 14-3-3 mediates cell cycle and cell death in neurons.

Journal

J Biol Chem 284:24512-25 (2009)
DOI:10.1074/jbc.M109.026237

Sequence

[hsa:6733]

LinkDB

DBGET integrated database retrieval system