KEGG   ORTHOLOGY: K08848
Entry
K08848                      KO                                     
Symbol
RIPK4
Name
receptor-interacting serine/threonine-protein kinase 4 [EC:2.7.11.1]
Disease
H01931  Lethal-type popliteal pterygium syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K08848  RIPK4; receptor-interacting serine/threonine-protein kinase 4
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K08848  RIPK4; receptor-interacting serine/threonine-protein kinase 4
Protein kinases [BR:ko01001]
 Serine/threonine kinases: TKL group
  RIPK family [OT]
   K08848  RIPK4; receptor-interacting serine/threonine-protein kinase 4
Genes
HSA: 54101(RIPK4)
PTR: 470094(RIPK4)
PPS: 100986703(RIPK4)
GGO: 101135791(RIPK4)
PON: 100446068(RIPK4)
NLE: 100599105(RIPK4)
HMH: 116481640(RIPK4)
MCC: 715077(RIPK4)
MCF: 102136693(RIPK4)
MTHB: 126951523
MNI: 105472598(RIPK4)
CSAB: 103219215(RIPK4)
CATY: 105575475(RIPK4)
PANU: 101023465(RIPK4)
TGE: 112620657(RIPK4)
MLEU: 105555571(RIPK4)
RRO: 104662451(RIPK4)
RBB: 108517326(RIPK4)
PTEH: 111524394(RIPK4)
CANG: 105520375(RIPK4)
CJC: 100407890(RIPK4)
SBQ: 101041422(RIPK4)
CIMI: 108311234(RIPK4)
CSYR: 103260550(RIPK4)
MMUR: 105863074(RIPK4)
LCAT: 123630757(RIPK4)
PCOQ: 105806902(RIPK4)
OGA: 100946653(RIPK4)
MMU: 72388(Ripk4)
MCAL: 110311557(Ripk4)
MPAH: 110329811(Ripk4)
RNO: 304053(Ripk4)
MCOC: 116086192(Ripk4)
ANU: 117718261(Ripk4)
MUN: 110561090(Ripk4)
CGE: 100763487(Ripk4)
MAUA: 101843406(Ripk4)
PROB: 127226678 127227569(Ripk4)
PLEU: 114685663(Ripk4)
MORG: 121461626(Ripk4)
MFOT: 126513648
AAMP: 119825670(Ripk4)
NGI: 103729323(Ripk4)
HGL: 101714815(Ripk4)
CPOC: 100721127(Ripk4)
CCAN: 109697917(Ripk4)
DORD: 105993953(Ripk4)
DSP: 122114305(Ripk4)
PLOP: 125351438(Ripk4)
NCAR: 124993385
MMMA: 107136496(Ripk4)
OCU: 103347402
OPI: 101518894(RIPK4)
TUP: 102497449(RIPK4)
GVR: 103605282(RIPK4)
CFA: 487772(RIPK4)
CLUD: 112669159(RIPK4)
VVP: 112908020(RIPK4)
VLG: 121479569(RIPK4)
NPO: 129502156(RIPK4)
AML: 100473893(RIPK4)
UMR: 103680772(RIPK4)
UAH: 113256130(RIPK4)
UAR: 123802647(RIPK4)
ELK: 111155808
LLV: 125093938
MPUF: 101669875(RIPK4)
MNP: 132012418(RIPK4)
MLK: 131825396(RIPK4)
NVS: 122908276(RIPK4)
ORO: 101383973(RIPK4)
EJU: 114226429(RIPK4)
ZCA: 113918820(RIPK4)
MLX: 118026122(RIPK4)
NSU: 110571121(RIPK4)
LWW: 102730648(RIPK4)
FCA: 101095278(RIPK4)
PYU: 121035912(RIPK4)
PCOO: 112849458(RIPK4)
PBG: 122491146(RIPK4)
PVIV: 125159077(RIPK4)
LRUF: 124527325
PPAD: 109256952(RIPK4)
PUC: 125920697
AJU: 106987725
HHV: 120240694(RIPK4)
BTA: 508668(RIPK4)
BOM: 102277101(RIPK4)
BIU: 109560505(RIPK4)
BBUB: 102410903(RIPK4)
BBIS: 104985023(RIPK4)
CHX: 102189168(RIPK4)
OAS: 101103283(RIPK4)
BTAX: 128056990(RIPK4)
ODA: 120856740(RIPK4)
CCAD: 122445358(RIPK4)
MBEZ: 129547976(RIPK4)
SSC: 100518276(RIPK4)
CFR: 102511857(RIPK4)
CBAI: 105078046(RIPK4)
CDK: 105101651(RIPK4)
VPC: 102534501(RIPK4)
BACU: 103013604(RIPK4)
BMUS: 118894395(RIPK4)
LVE: 103084589(RIPK4)
OOR: 101276899(RIPK4)
DLE: 111163860(RIPK4)
PCAD: 102977541(RIPK4)
PSIU: 116752552(RIPK4)
NASI: 112408537(RIPK4)
ECB: 100058408(RIPK4)
EPZ: 103544823(RIPK4)
EAI: 106829940(RIPK4)
MYB: 102255072(RIPK4)
MYD: 102768781(RIPK4)
MMYO: 118675063(RIPK4)
MLF: 102420518(RIPK4)
PKL: 118722630(RIPK4)
EFUS: 103289803(RIPK4)
MNA: 107543431(RIPK4)
DRO: 112306024(RIPK4)
SHON: 118984846(RIPK4)
AJM: 119048816(RIPK4)
PDIC: 114491098(RIPK4)
PHAS: 123828071(RIPK4)
MMF: 118617263(RIPK4)
PPAM: 129072685(RIPK4)
HAI: 109395173(RIPK4)
RFQ: 117012847(RIPK4)
PALE: 102895420(RIPK4)
PGIG: 120598657(RIPK4)
PVP: 105300584(RIPK4)
RAY: 107504923(RIPK4)
MJV: 108383805(RIPK4)
TOD: 119257180(RIPK4)
SARA: 101546610(RIPK4)
SETR: 126025662(RIPK4)
LAV: 100655582(RIPK4)
TMU: 101349657
ETF: 101652972(RIPK4)
DNM: 101422331(RIPK4)
MDO: 100016114(RIPK4)
GAS: 123242512(RIPK4)
SHR: 100918543(RIPK4)
AFZ: 127553773
PCW: 110200871(RIPK4)
OAA: 100080436(RIPK4)
GGA: 418529(RIPK4)
PCOC: 116242040(RIPK4)
MGP: 104914424(RIPK4)
CJO: 107323639(RIPK4)
TPAI: 128076512(RIPK4)
LMUT: 125702951(RIPK4)
NMEL: 110403166(RIPK4)
APLA: 101795987(RIPK4)
ACYG: 106036055(RIPK4)
CATA: 118247626(RIPK4)
AFUL: 116494527(RIPK4)
TGU: 100228035(RIPK4)
LSR: 110475861(RIPK4)
SCAN: 103815743(RIPK4)
PMOA: 120511900(RIPK4)
OTC: 121333508(RIPK4)
PRUF: 121364485(RIPK4)
GFR: 102038350(RIPK4)
FAB: 101814635(RIPK4)
OMA: 130256365(RIPK4)
PHI: 102110651(RIPK4)
PMAJ: 107212544(RIPK4)
CCAE: 111926739(RIPK4)
CCW: 104686272(RIPK4)
CBRC: 103612878(RIPK4)
ETL: 114059211(RIPK4)
ZAB: 102074895(RIPK4)
ACHL: 103805329(RIPK4)
SVG: 106855752(RIPK4)
MMEA: 130578110(RIPK4)
HRT: 120749649(RIPK4)
FPG: 101918944(RIPK4)
FCH: 102050451(RIPK4)
CLV: 102089153(RIPK4)
EGZ: 104128188(RIPK4)
NNI: 104020197(RIPK4)
PCRI: 104030531(RIPK4)
PLET: 104620308(RIPK4)
EHS: 104512306(RIPK4)
PCAO: 104049572
ACUN: 113478925(RIPK4)
TALA: 104361080(RIPK4)
PADL: 103920339(RIPK4)
AFOR: 103902092(RIPK4)
ACHC: 115344104(RIPK4)
HALD: 104318495(RIPK4)
HLE: 104839794(RIPK4)
AGEN: 126053151
GCL: 127019455
CCRI: 104158822
CSTI: 104549797(RIPK4)
CMAC: 104485266(RIPK4)
MUI: 104546160(RIPK4)
BREG: 104635354(RIPK4)
FGA: 104083156(RIPK4)
GSTE: 104255065(RIPK4)
LDI: 104353108(RIPK4)
MNB: 103771249(RIPK4)
OHA: 104327751(RIPK4)
NNT: 104403601(RIPK4)
SHAB: 115603782(RIPK4)
DPUB: 104305044(RIPK4)
PGUU: 104461342(RIPK4)
ACAR: 104526816(RIPK4)
CPEA: 104391217(RIPK4)
AVIT: 104274191
CVF: 104292053(RIPK4)
RTD: 128904465(RIPK4)
CUCA: 104059269(RIPK4)
TEO: 104382912(RIPK4)
BRHI: 104495155(RIPK4)
AAM: 106494906(RIPK4)
AROW: 112971891(RIPK4)
NPD: 112959103(RIPK4)
TGT: 104577010(RIPK4)
DNE: 112996183(RIPK4)
SCAM: 104147149(RIPK4)
ASN: 102386620(RIPK4)
AMJ: 102567026(RIPK4)
CPOO: 109305839(RIPK4)
GGN: 109302321(RIPK4)
PSS: 102448356(RIPK4)
CMY: 102948281(RIPK4)
CCAY: 125643416(RIPK4)
DCC: 119860706(RIPK4)
CPIC: 101940394(RIPK4)
TST: 117867847(RIPK4)
CABI: 116821858(RIPK4)
MRV: 120377201(RIPK4)
ACS: 100551928(ripk4)
ASAO: 132771828(RIPK4)
PVT: 110090888(RIPK4)
SUND: 121926207(RIPK4)
PBI: 103065651(RIPK4)
PMUR: 107293434(RIPK4)
CTIG: 120319882(RIPK4)
TSR: 106541128(RIPK4)
PGUT: 117669470(RIPK4)
APRI: 131199566(RIPK4)
PTEX: 113444749(RIPK4)
NSS: 113416239(RIPK4)
VKO: 123029370(RIPK4)
PMUA: 114596106(RIPK4) 114596475
PRAF: 128413039(RIPK4)
ZVI: 118085128(RIPK4)
HCG: 128352265(RIPK4)
GJA: 107112598(RIPK4)
STOW: 125430444(RIPK4)
EMC: 129326733(RIPK4)
XLA: 108709253 380107(ripk4.L)
XTR: 733737(ripk4)
NPR: 108799000(RIPK4)
RTEM: 120927980(RIPK4)
BBUF: 120993606 120994461
BGAR: 122924251 122931681 122931682
MUO: 115470559(RIPK4)
GSH: 117359471(RIPK4)
DRE: 406351(ripk4)
SRX: 107734463(ripk4)
SANH: 107686166 107697415(ripk4)
SGH: 107577855 107589146
CAUA: 113054463 113110050
CGIB: 127966485 128021046
PTET: 122353185(ripk4)
LROH: 127171843(ripk4)
OMC: 131547696(ripk4)
PPRM: 120482853(ripk4)
RKG: 130074096(ripk4)
MAMB: 125262729(ripk4)
CIDE: 127521524
MASI: 127432480 127433618
TROS: 130546486(ripk4)
TDW: 130412040(ripk4)
MANU: 129446772(ripk4)
IPU: 108276686
IFU: 128620340(ripk4)
PHYP: 113543437(ripk4)
SMEO: 124393930(ripk4)
TFD: 113637641(ripk4)
TVC: 132863063(ripk4)
AMEX: 103022568(ripk4)
CMAO: 118824783(ripk4)
EEE: 113572174(ripk4)
CHAR: 105900372(ripk4)
TRU: 101067291(ripk4)
TFS: 130537903(ripk4)
TNG: GSTEN00016300G001
LCO: 104931792(ripk4)
NCC: 104964820(ripk4)
TBEN: 117472168(ripk4)
CGOB: 115018982(ripk4)
PGEO: 117458649 117458650(ripk4)
GACU: 117553087(ripk4)
EMAC: 134872557(ripk4)
ELY: 117261848(ripk4)
EFO: 125899013(ripk4)
PLEP: 121952822(ripk4)
SLUC: 116058099(ripk4)
ECRA: 117955814(ripk4)
ESP: 116700509(ripk4)
PFLV: 114566743(ripk4)
GAT: 120822914(ripk4)
PPUG: 119215033(ripk4)
AFB: 129113791(ripk4)
CLUM: 117743256(ripk4)
PSWI: 130191760(ripk4)
MSAM: 119895791(ripk4)
SCHU: 122888483(ripk4)
CUD: 121518338(ripk4)
ALAT: 119031629(ripk4)
MZE: 101487965(ripk4)
ONL: 100698179(ripk4)
OAU: 116320583(ripk4)
OLA: 101174941(ripk4)
OML: 112143011(ripk4)
CSAI: 133459852(ripk4)
XMA: 102218553(ripk4)
XCO: 114152988(ripk4)
XHE: 116728187(ripk4)
PRET: 103476114(ripk4)
PFOR: 103142106(ripk4)
PLAI: 106951563(ripk4)
PMEI: 106903712(ripk4)
GAF: 122844949(ripk4)
PPRL: 129368790(ripk4)
CVG: 107104105(ripk4)
CTUL: 119775788(ripk4)
GMU: 124876127(ripk4)
NFU: 107386002(ripk4)
KMR: 108244693(ripk4)
ALIM: 106530313(ripk4)
NWH: 119420711(ripk4)
AOCE: 111575186(ripk4)
MCEP: 125021777(ripk4)
CSEM: 103394831(ripk4)
POV: 109628815(ripk4)
SSEN: 122780229(ripk4)
HHIP: 117774545(ripk4)
HSP: 118122575(ripk4)
SMAU: 118301322(ripk4)
LCF: 108893949
SDU: 111222232(ripk4)
SLAL: 111663486(ripk4)
XGL: 120803101(ripk4)
HCQ: 109531154(ripk4)
SSCV: 125982644
SBIA: 133492155(ripk4)
PEE: 133416425(ripk4)
PTAO: 133467002(ripk4)
BPEC: 110165011 110165012
MALB: 109972858(ripk4)
BSPL: 114869758(ripk4)
SJO: 128371600(ripk4)
SASA: 106567956 106603528
STRU: 115148884 115154342
OTW: 112245078 112257836
OMY: 110533655 110537467
OGO: 124000536 124010478
ONE: 115105555 115135901
OKI: 109873496 109892731(ripk4)
OKE: 118390091 118391167
SALP: 111950667 111981436
SNH: 120045193 120057073
CCLU: 121573572 121579771
ELS: 105011005(ripk4)
SFM: 108936245(ripk4)
PKI: 111854805(ripk4)
AANG: 118209062 118236663
LOC: 102686869(ripk4)
PSPA: 121321270(ripk4)
ARUT: 117405134 117971241
PSEX: 120523337(ripk4)
LCM: 102363747(RIPK4)
CMK: 103187277(ripk4)
RTP: 109929365(ripk4)
CPLA: 122555402(ripk4)
HOC: 132821187(ripk4)
LERI: 129702985(ripk4)
PMRN: 116945943
LRJ: 133340452
 » show all
Reference
PMID:11278382
  Authors
Chen L, Haider K, Ponda M, Cariappa A, Rowitch D, Pillai S
  Title
Protein kinase C-associated kinase (PKK), a novel membrane-associated, ankyrin repeat-containing protein kinase.
  Journal
J Biol Chem 276:21737-44 (2001)
DOI:10.1074/jbc.M008069200
  Sequence
[mmu:72388]
Reference
PMID:12446564
  Authors
Meylan E, Martinon F, Thome M, Gschwendt M, Tschopp J
  Title
RIP4 (DIK/PKK), a novel member of the RIP kinase family, activates NF-kappa B and is processed during apoptosis.
  Journal
EMBO Rep 3:1201-8 (2002)
DOI:10.1093/embo-reports/kvf236
  Sequence
[mmu:72388]
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