KEGG ORTHOLOGY: K09055

ORTHOLOGY: K09055

Entry

K09055                      KO

Symbol

CEBPA

Name

CCAAT/enhancer binding protein (C/EBP), alpha

Pathway

map04932

Non-alcoholic fatty liver disease

map05200

Pathways in cancer

map05202

Transcriptional misregulation in cancer

map05221

Acute myeloid leukemia

Disease

H00003

Acute myeloid leukemia

H02410

Myelodysplastic/myeloproliferative neoplasms

H02412

Atypical chronic myeloid leukemia

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K09055  CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
   05202 Transcriptional misregulation in cancer
    K09055  CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    K09055  CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K09055  CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K09055  CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
Transcription factors [BR:ko03000]
Eukaryotic type
  Basic leucine zipper (bZIP)
   C/EBP-like factors
    K09055  CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha

Genes

HSA:	1050(CEBPA)

PTR:	746673(CEBPA)

PPS:	100984674(CEBPA)

GGO:	101129792(CEBPA)

PON:	100442871(CEBPA)

PPYG:

129020415(CEBPA)

NLE:	100604930(CEBPA)

HMH:	116478857(CEBPA)

SSYN:

129460428(CEBPA)

MCC:	717153(CEBPA)

MCF:	102119204(CEBPA)

MTHB:

126941775

MNI:	105495586(CEBPA)

CSAB:

103234457(CEBPA)

CATY:

105578124(CEBPA)

PANU:

101014747(CEBPA)

TGE:	112613494(CEBPA)

RRO:	104659570(CEBPA)

RBB:	108517258(CEBPA)

TFN:	117092292(CEBPA)

PTEH:

111553915(CEBPA)

CJC:	103796367(CEBPA)

SBQ:	104651063(CEBPA)

CIMI:

108286404(CEBPA)

ANAN:

105714505(CEBPA)

MMUR:

105876979(CEBPA)

LCAT:

123624269(CEBPA)

ERUF:

138375017(CEBPA)

PCOQ:

105812560(CEBPA)

OGA:	100954648(CEBPA)

MMU:	12606(Cebpa)

MCAL:

110298970(Cebpa)

MPAH:

110324171(Cebpa)

RNO:	24252(Cebpa)

MCOC:

116102026(Cebpa)

ANU:	117697881(Cebpa)

ASYL:

127670956(Cebpa)

MMIU:

308414080(CEBPA)

MUN:	110551365(Cebpa)

CGE:

113837181

MAUA:

101828666(Cebpa)

PROB:

127238653(Cebpa)

PLEU:

114698911(Cebpa)

PMAV:

102919815(Cebpa)

MORG:

121450040(Cebpa)

MFOT:

126486797

AAMP:

119820636(Cebpa)

CNL:	130870432(Cebpa)

NGI:	103739150(Cebpa)

HGL:	101726330(Cebpa)

CPOC:

101787350(Cebpa)

DORD:

105993173(Cebpa)

DSP:	122097604(Cebpa)

DMER:

138811055(Cebpa)

PLOP:

125338679(Cebpa)

NCAR:

124967539

SVUL:

306648411(CEBPA)

SCIL:

308637618(CEBPA)

MAVE:

308268995(CEBPA)

OCU:

100358602

OPI:	101523640(CEBPA)

OCZ:	121153739(CEBPA)

GVR:	103598950(CEBPA)

CFA:	100683573(CEBPA)

CLUD:

112645571(CEBPA)

VVP:	112928337(CEBPA)

VLG:	121484054(CEBPA)

NPO:	129499647(CEBPA)

AML:	100469640(CEBPA)

UMR:	103679654(CEBPA)

UAH:	113244730(CEBPA)

UAR:	123791396(CEBPA)

ELK:

111161485

LLV:

125089775

MPUF:

101689073(CEBPA)

MNP:	132004932(CEBPA)

MLK:	131818237(CEBPA)

NVS:	122911517(CEBPA)

MMAQ:

308357918(CEBPA)

ORO:	101368354(CEBPA)

EJU:	114224343(CEBPA)

ZCA:	113936709(CEBPA)

MLX:	118022727(CEBPA)

MANO:

123855520(CEBPA)

NSU:	110590252(CEBPA)

LWW:	102747288(CEBPA)

FCA:	105261262(CEBPA)

PYU:	121011621(CEBPA)

PCOO:

112851250(CEBPA)

PBG:	122494136(CEBPA)

PVIV:

125153680(CEBPA)

LRUF:

124511262

LGF:	123579043(CEBPA)

AJU:

106975747

PPAD:

109251606(CEBPA)

PUC:

125915200

PLEZ:

122208002(CEBPA)

HHV:	120231685(CEBPA)

CCRU:

144223896(CEBPA)

BTA:	281677(CEBPA)

BOM:	102264854(CEBPA)

BJV:	133230437(CEBPA)

BBUB:

102410413(CEBPA)

BKE:	129631119(CEBPA)

BBIS:

104995397(CEBPA)

CHX:	102177713(CEBPA)

OAS:	101118553(CEBPA)

OCAN:

138418105(CEBPA)

BTAX:

128063910(CEBPA)

CSUM:

138095955(CEBPA)

ODA:	120872642(CEBPA)

CCAD:

122421192(CEBPA)

MREE:

136158747(CEBPA)

OVR:	110140655(CEBPA)

MBEZ:

129546897(CEBPA)

SSC:	397307(CEBPA)

CFR:	102510087(CEBPA)

CBAI:

105065000(CEBPA)

CDK:	105096715(CEBPA)

VPC:	102529437(CEBPA)

BACU:

103013093(CEBPA)

BMUS:

118885699(CEBPA)

LVE:	103076258(CEBPA)

OOR:	101272824(CEBPA)

LALB:

132509887(CEBPA)

GMF:	115862515(CEBPA)

DDP:	132417171(CEBPA)

SCOO:

307179289(CEBPA)

PCRS:

137214387(CEBPA)

DLE:	111180929(CEBPA)

PCAD:

102976371(CEBPA)

PSIU:

116744672(CEBPA)

PPHC:

136140540(CEBPA)

NASI:

112392377(CEBPA)

HAMP:

307066982(CEBPA)

ECB:	111775177(CEBPA)

EPZ:	103554828(CEBPA)

EAI:	106827744(CEBPA)

MMYO:

118674315(CEBPA)

MDT:	132217053(CEBPA)

MYUM:

138996825(CEBPA)

PKL:	118720508(CEBPA)

EFUS:

103284477(CEBPA)

POTS:

308235406(CEBPA)

MNA:	107543384(CEBPA)

DRO:	112320127(CEBPA)

SHON:

118976331(CEBPA)

AJM:	119044685(CEBPA)

PDIC:

114511592(CEBPA)

PHAS:

123823885(CEBPA)

MMF:	118638917(CEBPA)

PPAM:

129083167(CEBPA)

HAI:	109389201(CEBPA)

RFQ:	117035008(CEBPA)

RHII:

308490104(CEBPA)

PALE:

102893139(CEBPA)

PGIG:

120622859(CEBPA)

PVP:	105299891(CEBPA)

RAY:	107504204(CEBPA)

MJV:	108384330(CEBPA)

TOD:	119250416(CEBPA)

SARA:

101553119(CEBPA)

SFUM:

130044268(CEBPA)

SETR:

126027634(CEBPA)

LAV:	100664106(CEBPA)

TMU:

101344839

DNM:	101413319(CEBPA)

MDO:	100012502(CEBPA)

GAS:	123235337(CEBPA) 123254444

SHR:	100933872(CEBPA)

AFZ:

127550635

PCW:	110207402(CEBPA)

TVP:	118844397(CEBPA)

PBRV:

138157137(CEBPA)

MLAO:

141517233(CEBPA)

OAA:	100078506(CEBPA)

TACU:

119935096(CEBPA)

GGA:	427549(CEBPA)

PCOC:

116244008(CEBPA)

MGP:

104916462

CJO:	107319256(CEBPA)

TPAI:

128082018(CEBPA)

LMUT:

125699285(CEBPA)

NMEL:

110404144(CEBPA)

APLA:

110351216(CEBPA)

AACU:

137862090(CEBPA)

OJA:	118172966(CEBPA)

BCLA:

308448511(CEBPA)

ACYG:

125183364(CEBPA)

ABRC:

308176676(CEBPA)

CATA:

118246543(CEBPA)

AFUL:

116494141(CEBPA)

TGU:	100224425(CEBPA)

LSR:	110473814(CEBPA)

VMC:	128813007(CEBPA)

VCHA:

128793816(CEBPA)

AIB:	137481044(CEBPA)

SCAN:

103821195(CEBPA)

PMOA:

120497097(CEBPA)

OTC:	121331655(CEBPA)

PRUF:

121365953(CEBPA)

ATRC:

139596194(CEBPA)

MATE:

118691477(CEBPA)

MAEN:

136561195(CEBPA)

FAB:	101820757(CEBPA)

OMA:	130257871(CEBPA)

PHI:	102105328(CEBPA)

PMAJ:

107209607(CEBPA)

CCAE:

111934844(CEBPA)

CCW:	104687389(CEBPA)

ACOE:

138117245(CEBPA)

ETL:	114069070(CEBPA)

ZAB:	102069192(CEBPA)

ZLE:	135452928(CEBPA)

SVG:	106856520(CEBPA)

MMEA:

130578306(CEBPA)

HRT:	120757710(CEBPA)

SATI:

136366706(CEBPA)

CFAI:

136296059(CEBPA)

CCIC:

134048318(CEBPA)

SHAB:

115600822(CEBPA) 115619121

POCC:

134156681(CEBPA)

FPG:	101910670(CEBPA)

FCH:	102046165(CEBPA)

FRS:	119157946(CEBPA)

ANOC:

141963877(CEBPA)

SURA:

141948886(CEBPA)

TALA:

116960241(CEBPA)

ACHC:

115346321(CEBPA)

HLE:	104842628(CEBPA)

AGEN:

126041161

HHAR:

128146239(CEBPA)

BBUT:

142036662(CEBPA)

GCL:

127021022

PPUS:

135184277(CEBPA)

IIN:	128973485(CEBPA)

NNI:	104013297(CEBPA)

PARX:

142060983(CEBPA)

AFOR:

103901877(CEBPA)

CBOR:

142087283(CEBPA)

CBOY:

140656455(CEBPA)

MAME:

142413981(CEBPA)

CLV:	102084198(CEBPA)

CNIC:

135992020(CEBPA)

NMAY:

308045179(CEBPA)

CUCA:

104065466(CEBPA)

PCUR:

138726636(CEBPA)

GAME:

129212141(CEBPA)

CEUR:

306724415(CEBPA)

HEK:	139802016(CEBPA)

RTD:	128908709(CEBPA)

CRID:

134515511(CEBPA)

LMIC:

141741858(CEBPA)

NARQ:

141471545(CEBPA)

AAM:	106483310(CEBPA)

AROW:

112963156(CEBPA)

NPD:	112945038(CEBPA)

DNE:	112987621(CEBPA)

AMJ:	102575011(CEBPA)

GGN:	109289287(CEBPA)

PSS:	102448303(CEBPA)

CIZ:	142020579(CEBPA)

CMY:	102945949(CEBPA)

CCAY:

125645366(CEBPA)

LKP:	140896292(CEBPA)

NDS:	141996591(CEBPA)

DCC:	119841424(CEBPA)

CPIC:

101951046(CEBPA)

TST:	117886676(CEBPA)

EOB:	135888778(CEBPA)

CABI:

116820697(CEBPA)

MRV:	120384869(CEBPA)

EMQ:	137147724(CEBPA)

ACS:

100562398

ASAO:

132782993(CEBPA)

PVT:	110081279(CEBPA)

SUND:

121914286(CEBPA)

PMUR:

107284070(CEBPA)

CTIG:

120312659(CEBPA)

TSR:	106553889(CEBPA)

PGUT:

117670429(CEBPA)

PCAE:

139323422(CEBPA)

APRI:

131184330(CEBPA)

PTEX:

113445329(CEBPA)

NSS:	113420299(CEBPA)

VKO:	123025511(CEBPA)

PMUA:

114601814(CEBPA)

PRAF:

128419037(CEBPA)

ZVI:	118087559(CEBPA)

HCG:	128334092(CEBPA)

GJA:	107121021(CEBPA)

STOW:

125443903(CEBPA)

EMC:	129344229(CEBPA)

XLA:	379967(cebpa.L) 432238(cebpa.S)

XTR:	496454(cebpa)

NPR:	108801521(CEBPA)

RTEM:

120917865(CEBPA)

ACAT:

141112741 141112742(CEBPA)

PADS:

140338021(CEBPA)

BBUF:

120981041(CEBPA)

BGAR:

122920702(CEBPA)

DTC:	141073575(CEBPA)

HSQ:	130277655(CEBPA)

PWL:	138267519(CEBPA)

MUO:	115470849(CEBPA)

GSH:	117359998(CEBPA)

DRE:	140815(cebpa)

DAES:

130232108(cebpa)

SRX:	107722391 107733057

SANH:

107657126 107696713

SGH:	107551484 107580367

CCAR:

109093467 109093469

CAUA:

113051423 113106064

CGIB:

127961593 128016841

PTET:

122349093(cebpa)

LROH:

127167965(cebpa)

GRF:	141331973(cebpa)

OMC:	131543994(cebpa)

PPRM:

120468788(cebpa)

RKG:	130069768(cebpa)

SCEP:

307156093(cebpa)

MAMB:

125265052(cebpa)

CIDE:

127515352

CERY:

137031337(cebpa)

MASI:

127444191 127453625

TROS:

130562172(cebpa)

TDW:	130424229(cebpa)

MANU:

129444928(cebpa)

PDAB:

135778887(cebpa)

IPU:

108259657

IFU:	128602854(cebpa)

PHYP:

113540779(cebpa)

SMEO:

124380220(cebpa)

TFD:	113656376(cebpa)

TVC:	132838687(cebpa)

CGAR:

128519522(cebpa)

NGRA:

132874845(cebpa)

TRN:	134304255(cebpa)

AMEX:

103047262(cebpa)

CMAO:

118817426(cebpa)

EEE:	113591773(cebpa)

CHAR:

105901333(cebpa)

SPIL:

134069492(cebpa)

ASAD:

121694371(cebpa)

TRU:	101068077(cebpa)

TFS:	130520379(cebpa)

TNG:	GSTEN00004553G001

NCC:	104964000(cebpa)

TBEN:

117473273 117491978

CGOB:

115005597

GACU:

117557342

EMAC:

134863644(cebpa)

ELY:	117252917(cebpa)

EFO:	125904003(cebpa)

PLEP:

121945744(cebpa)

SLUC:

116067631(cebpa)

ECRA:

117940091(cebpa)

PFLV:

114551623(cebpa)

GAT:	120835463(cebpa)

PPUG:

119197706(cebpa)

AFB:	129104430(cebpa)

CLUM:

117728783(cebpa)

PSWI:

130192175(cebpa)

CANA:

137792717(cebpa)

CVE:	137886356(cebpa)

MSAM:

119890039(cebpa)

SCHU:

122877709(cebpa)

EARM:

139286700(cebpa)

CUD:	121512631(cebpa)

SPUL:

138592299(cebpa)

LMIX:

132984406(cebpa)

HTC:	141787371(cebpa)

ALAT:

119017550(cebpa)

ASTR:

137589086(cebpa)

PKLU:

139198710(cebpa)

MZE:	101474797(cebpa)

ONL:	100692663(cebpa)

OAU:	116323372(cebpa)

OLA:	101167854(cebpa)

OML:	112160306(cebpa)

CSAI:

133457280(cebpa)

XMA:	102236533(cebpa)

XCO:	114143307(cebpa)

XHE:	116718137(cebpa)

PRET:

103460084(cebpa)

PFOR:

103156893(cebpa)

PLAI:

106941808(cebpa)

PMEI:

106909949(cebpa)

GAF:	122823521(cebpa)

PPRL:

129355790

CVG:	107099283(cebpa)

CTUL:

119771455(cebpa)

GMU:	124867651(cebpa)

NFU:	107381504(cebpa)

KMR:	108247032(cebpa)

ALIM:

106532971(cebpa)

NWH:	119430291(cebpa)

LTU:	140301418(cebpa)

MCEP:

125005572(cebpa)

AOCE:

111581072(cebpa)

EJA:	138213882(cebpa)

BFRE:

138632694(cebpa)

LCF:

108894277

CSEM:

103378943(cebpa)

POV:	109645743(cebpa)

SSEN:

122772607(cebpa)

SSOE:

131459705(cebpa)

HHIP:

117752496(cebpa)

HSP:	118101467(cebpa)

PPLT:

128445508(cebpa)

SMAU:

118301995(cebpa)

SDU:	111225157(cebpa)

SLAL:

111656717(cebpa)

XGL:	120804040(cebpa)

HCQ:	109529764(cebpa)

SSCV:

125966659(cebpa)

SBIA:

133498455(cebpa)

PEE:	133414866(cebpa)

PTAO:

133469758(cebpa)

BPEC:

110159947(cebpa)

ENY:	140381210(cebpa)

MALB:

109961676(cebpa)

BSPL:

114852191(cebpa)

SJO:	128359656(cebpa)

SSCO:

133983090(cebpa)

TTY:	137179499(cebpa)

GMH:	115558850(cebpa)

SASA:

100194902(cebpa) 106562806

STRU:

115203714 115203715

OTW:	112241779(cebpa)

OMY:	100379111 110507010

OGO:	124018645 124018647

ONE:	115117064(cebpa)

OKI:	109885280(cebpa)

OKE:	118383419 127928253

OMM:	135536245(cebpa)

OCLA:

139396921 139401118

SALP:

112078506(cebpa)

SNH:	120037181 120037665

SFON:

129842862(cebpa)

CCLU:

121556214(cebpa)

ELS:	105030623(cebpa)

OEP:	134028054(cebpa)

SFM:	108926260 108940956(cebpa)

PKI:	111843507 111861186(cebpa)

AANG:

118215561(cebpa)

AROT:

135242736(cebpa)

CCOG:

133111575(cebpa)

LOC:	102688411(cebpa)

PSPA:

121296543 121326199

ARUT:

117424237 117425372

PSEX:

120535617(cebpa)

LCM:	102355541(CEBPA)

CMK:	103188072(cebpa)

RTP:	125482280(cebpa)

CPLA:

122546721(cebpa)

LERI:

129705273(cebpa)

HAKA:

140740887(cebpa)

PMRN:

LRJ:

SPU:

SOY:

PJA:

EPA:

Reference

PMID:20422469

Authors

Reckzeh K, Cammenga J

Title

Molecular mechanisms underlying deregulation of C/EBPalpha in acute myeloid leukemia.

Journal

Int J Hematol 91:557-68 (2010)
DOI:10.1007/s12185-010-0573-1

Reference

PMID:7575576

Authors

Antonson P, Xanthopoulos KG

Title

Molecular cloning, sequence, and expression patterns of the human gene encoding CCAAT/enhancer binding protein alpha (C/EBP alpha).

Journal

Biochem Biophys Res Commun 215:106-13 (1995)
DOI:10.1006/bbrc.1995.2439

Sequence

[hsa:1050]

LinkDB

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