KEGG   ORTHOLOGY: K09821
Entry
K09821                      KO                                     
Symbol
AGT, SERPINA8
Name
angiotensinogen
Pathway
map04072  Phospholipase D signaling pathway
map04080  Neuroactive ligand-receptor interaction
map04261  Adrenergic signaling in cardiomyocytes
map04270  Vascular smooth muscle contraction
map04614  Renin-angiotensin system
map04924  Renin secretion
map04925  Aldosterone synthesis and secretion
map04927  Cortisol synthesis and secretion
map04931  Insulin resistance
map04933  AGE-RAGE signaling pathway in diabetic complications
map04934  Cushing syndrome
map05200  Pathways in cancer
map05410  Hypertrophic cardiomyopathy
map05414  Dilated cardiomyopathy
map05415  Diabetic cardiomyopathy
Disease
H00575  Renal tubular dysgenesis
H01633  High blood pressure
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    K09821  AGT, SERPINA8; angiotensinogen
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K09821  AGT, SERPINA8; angiotensinogen
 09150 Organismal Systems
  09152 Endocrine system
   04924 Renin secretion
    K09821  AGT, SERPINA8; angiotensinogen
   04614 Renin-angiotensin system
    K09821  AGT, SERPINA8; angiotensinogen
   04925 Aldosterone synthesis and secretion
    K09821  AGT, SERPINA8; angiotensinogen
   04927 Cortisol synthesis and secretion
    K09821  AGT, SERPINA8; angiotensinogen
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K09821  AGT, SERPINA8; angiotensinogen
   04270 Vascular smooth muscle contraction
    K09821  AGT, SERPINA8; angiotensinogen
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K09821  AGT, SERPINA8; angiotensinogen
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K09821  AGT, SERPINA8; angiotensinogen
   05414 Dilated cardiomyopathy
    K09821  AGT, SERPINA8; angiotensinogen
   05415 Diabetic cardiomyopathy
    K09821  AGT, SERPINA8; angiotensinogen
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    K09821  AGT, SERPINA8; angiotensinogen
   04933 AGE-RAGE signaling pathway in diabetic complications
    K09821  AGT, SERPINA8; angiotensinogen
   04934 Cushing syndrome
    K09821  AGT, SERPINA8; angiotensinogen
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K09821  AGT, SERPINA8; angiotensinogen
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K09821  AGT, SERPINA8; angiotensinogen
Peptidases and inhibitors [BR:ko01002]
 Peptidase inhibitors
  Family I4: serpin family
   K09821  AGT, SERPINA8; angiotensinogen
Cytokines and neuropeptides [BR:ko04052]
 Neuropeptides
  Neuropeptides (GPCR binding)
   K09821  AGT, SERPINA8; angiotensinogen
Other DBs
GO: 0004867 0031702 0031703
Genes
HSA: 183(AGT)
PTR: 450104(AGT)
PPS: 100990550(AGT)
GGO: 101141078(AGT)
PON: 100458106(AGT)
NLE: 100605443(AGT)
HMH: 116457859(AGT)
MCC: 714203(AGT)
MCF: 101926221(AGT)
MTHB: 126942065
MNI: 105499156(AGT)
CSAB: 103230737(AGT)
CATY: 105574840(AGT)
PANU: 101013870(AGT)
TGE: 112628065(AGT)
MLEU: 105528652(AGT)
RRO: 104670705(AGT)
RBB: 108537839(AGT)
TFN: 117074039(AGT)
PTEH: 111533277(AGT)
CANG: 105505479(AGT)
CJC: 100389395(AGT)
SBQ: 101040311(AGT)
CIMI: 108302783(AGT)
CSYR: 103276903(AGT)
MMUR: 105856439(AGT)
LCAT: 123627605(AGT)
PCOQ: 105823200(AGT)
OGA: 100944302(AGT)
MMU: 11606(Agt)
MCAL: 110299606(Agt)
MPAH: 110337308(Agt)
RNO: 24179(Agt)
MCOC: 116070395(Agt)
ANU: 117701700 117722914(Agt)
MUN: 110555411(Agt)
CGE: 100773858(Agt)
MAUA: 101824386(Agt)
PROB: 127234572(Agt)
PLEU: 114707150(Agt)
MORG: 121447304(Agt)
MFOT: 126504617
AAMP: 119801880(Agt)
NGI: 103744123(Agt)
HGL: 101717217(Agt)
CPOC: 100724950(Agt)
CCAN: 109701338(Agt)
DORD: 105984546(Agt)
DSP: 122113292(Agt)
PLOP: 125367128(Agt)
NCAR: 124961133
MMMA: 107157900(Agt)
OCU: 100358371
OPI: 101532109(AGT)
TUP: 102471092(AGT)
GVR: 103605394(AGT)
CFA: 403783(AGT)
CLUD: 112660805(AGT)
VVP: 112927331(AGT)
VLG: 121488092(AGT)
NPO: 129499243(AGT)
AML: 100470137(AGT)
UMR: 103661870(AGT)
UAH: 113259044(AGT)
UAR: 123783095(AGT)
ELK: 111160516
LLV: 125085161
MPUF: 101675397(AGT)
MNP: 132016189(AGT)
MLK: 131829099(AGT)
NVS: 122898883(AGT)
ORO: 101373565(AGT)
EJU: 114210362(AGT)
ZCA: 113923905(AGT)
MLX: 118012894(AGT)
NSU: 110586012(AGT)
LWW: 102742950(AGT)
FCA: 101093714(AGT)
PYU: 121023141(AGT)
PCOO: 112851576(AGT)
PBG: 122492757(AGT)
PVIV: 125148153(AGT)
LRUF: 124518614
PTG: 102964727(AGT)
PPAD: 109248942(AGT)
PUC: 125917496 125918486
AJU: 106983558
HHV: 120237807(AGT)
BTA: 527114(AGT)
BOM: 102274045(AGT)
BIU: 109553744(AGT)
BBUB: 102415383(AGT)
BBIS: 104999040(AGT)
CHX: 102187651(AGT)
OAS: 101119440(AGT)
BTAX: 128048317(AGT)
ODA: 120865479(AGT)
CCAD: 122446567(AGT)
MBEZ: 129555920(AGT)
SSC: 100157073(AGT)
CFR: 102506388(AGT)
CBAI: 105075087(AGT)
CDK: 105104282(AGT)
VPC: 102543577(AGT)
BACU: 103008704(AGT)
BMUS: 118882969(AGT)
LVE: 103078157(AGT)
OOR: 101287080(AGT)
DLE: 111163985(AGT)
PCAD: 102991481(AGT)
PSIU: 116742047(AGT)
NASI: 112413621(AGT)
ECB: 100065526(AGT)
EPZ: 103561130(AGT)
EAI: 106844922(AGT)
MYB: 102262829(AGT)
MMYO: 118678933(AGT)
MLF: 102429375(AGT)
PKL: 118718026(AGT)
EFUS: 103293490(AGT)
MNA: 107524243(AGT)
DRO: 112305985(AGT)
SHON: 118996691(AGT)
AJM: 119042933(AGT)
PDIC: 114512371(AGT)
PHAS: 123804835(AGT)
MMF: 118640739(AGT)
PPAM: 129073055(AGT)
HAI: 109395080(AGT)
RFQ: 117018614(AGT)
PALE: 102892951(AGT)
PGIG: 120592637(AGT)
PVP: 105306022(AGT)
RAY: 107520073(AGT)
MJV: 108386456(AGT)
TOD: 119244778(AGT) 119256515
SARA: 101553203(AGT)
SETR: 126013421(AGT)
LAV: 100670141(AGT)
TMU: 101351576
ETF: 101653271(AGT)
DNM: 101421064(AGT)
MDO: 100029465(AGT)
GAS: 123244984(AGT)
SHR: 100932795(AGT)
AFZ: 127559679
PCW: 110217880(AGT)
OAA: 100092976(AGT)
GGA: 421543(AGT)
PCOC: 116242721(AGT)
MGP: 104909692(AGT)
CJO: 107311450(AGT)
TPAI: 128081237(AGT)
LMUT: 125689151(AGT)
NMEL: 110395920(AGT)
APLA: 101801266(AGT)
ACYG: 106044579(AGT)
CATA: 118243918(AGT)
AFUL: 116488199(AGT)
TGU: 100226022(AGT)
LSR: 110468897(AGT)
SCAN: 103818499(AGT)
PMOA: 120501226(AGT)
OTC: 121346436(AGT)
PRUF: 121354205(AGT)
GFR: 102037997(AGT) 102041540
FAB: 101818773(AGT)
OMA: 130250893(AGT)
PHI: 102102481(AGT)
PMAJ: 107201998(AGT)
CCAE: 111926123 111926896(AGT)
CCW: 104684314(AGT)
CBRC: 103624101(AGT)
ETL: 114064468(AGT)
ZAB: 102060700(AGT)
ACHL: 103803245(AGT)
SVG: 106852570(AGT)
MMEA: 130577936(AGT)
HRT: 120749773(AGT)
FPG: 101920124(AGT)
FCH: 102048720(AGT)
CLV: 102090780(AGT)
EGZ: 104131062(AGT)
NNI: 104017811(AGT)
PCRI: 104037881(AGT)
PLET: 104619848(AGT)
EHS: 104508022(AGT)
PCAO: 104041862(AGT)
ACUN: 113478108(AGT)
TALA: 104355601(AGT)
PADL: 103921248(AGT)
AFOR: 103900971(AGT)
ACHC: 115349886(AGT)
HALD: 104311170(AGT)
HLE: 104828763(AGT)
AGEN: 126051640
GCL: 127015284
CCRI: 104160757(AGT)
CSTI: 104554754(AGT)
CMAC: 104476328(AGT)
MUI: 104548595(AGT)
BREG: 104632779
FGA: 104073288(AGT)
GSTE: 104251653(AGT)
LDI: 104342319(AGT)
MNB: 103778276(AGT)
OHA: 104332619(AGT)
NNT: 104404820(AGT)
SHAB: 115613651(AGT)
DPUB: 104305481(AGT)
PGUU: 104462551(AGT)
ACAR: 104520486 104521521
CPEA: 104394612(AGT)
AVIT: 104275708(AGT)
CVF: 104291861(AGT)
RTD: 128906867(AGT)
CUCA: 104064718(AGT)
TEO: 104379228(AGT)
BRHI: 104496464(AGT)
AAM: 106487365(AGT)
AROW: 112977868(AGT)
NPD: 112959353(AGT)
TGT: 104573654(AGT)
DNE: 112993518(AGT)
SCAM: 104147665(AGT)
ASN: 102386069(AGT)
AMJ: 102570643(AGT)
CPOO: 109320001(AGT)
GGN: 109304815(AGT)
PSS: 102444133(AGT)
CMY: 102945682(AGT)
CCAY: 125633921(AGT)
DCC: 119853781(AGT)
CPIC: 101953410(AGT)
TST: 117874731(AGT)
CABI: 116840034(AGT)
MRV: 120400906(AGT)
ACS: 100567502(agt)
ASAO: 132761162(AGT)
PVT: 110083076(AGT)
SUND: 121917087(AGT)
PBI: 103061181(AGT)
PMUR: 107295594(AGT)
CTIG: 120317656(AGT)
TSR: 106543591(AGT)
PGUT: 117672015(AGT)
APRI: 131190056(AGT)
PTEX: 113439338(AGT)
NSS: 113413323(AGT)
VKO: 123018523(AGT)
PMUA: 114594372(AGT)
PRAF: 128410793(AGT)
ZVI: 118081902(AGT)
HCG: 128345787(AGT)
GJA: 107119021(AGT)
STOW: 125427244(AGT)
EMC: 129341057(AGT)
XLA: 108716126(agt.L) 108717410(agt.S)
XTR: 100127178(agt)
RTEM: 120937441(AGT)
BBUF: 120998667(AGT)
BGAR: 122936192(AGT)
MUO: 115465738(AGT)
GSH: 117357906(AGT)
DRE: 322485(agt)
SRX: 107725476 107743538
SANH: 107666501 107676582
SGH: 107552950 107601848
CCAR: 109104962 109104968
CAUA: 113057014 113112682
CGIB: 127970357 128026239
PTET: 122357138(agt)
LROH: 127175558(agt)
OMC: 131552323(agt)
PPRM: 120480015(agt)
RKG: 130089687(agt)
MAMB: 125276874(agt)
CIDE: 127525489
MASI: 127411816 127413773
TROS: 130558808(agt)
TDW: 130431911(agt)
MANU: 129416771(agt)
IPU: 108263554
IFU: 128605946(agt)
PHYP: 113543818(agt)
SMEO: 124402667(agt)
TFD: 113642418(agt)
TVC: 132847533(agt)
AMEX: 103037865(agt)
CMAO: 118810568(agt)
EEE: 113571506(agt)
CHAR: 105888588(agt)
TRU: 101068970(agt)
TFS: 130533955(agt)
LCO: 104928870(agt)
NCC: 104960813(agt)
TBEN: 117499512(agt)
CGOB: 115020195(agt)
PGEO: 117459283(agt)
GACU: 117560731 117560843
EMAC: 134858626(agt)
ELY: 117247868(agt)
EFO: 125903084(agt)
PLEP: 121955030(agt)
SLUC: 116055721(agt)
ECRA: 117960464(agt)
ESP: 116704864(agt)
PFLV: 114571862(agt)
GAT: 120820780(agt)
PPUG: 119214472(agt)
AFB: 129092290(agt)
CLUM: 117744132(agt)
PSWI: 130207077(agt)
MSAM: 119917447(agt)
SCHU: 122884230(agt)
CUD: 121510700(agt)
ALAT: 119034038(agt)
MZE: 101472432(agt)
ONL: 100699886(agt)
OAU: 116322202(agt)
OLA: 101166899(agt)
OML: 112140908 112161371(agt)
CSAI: 133463381(agt)
XMA: 102229374(agt)
XCO: 114138386(agt)
XHE: 116713061(agt)
PRET: 103476745(agt)
PFOR: 103133580(agt)
PLAI: 106947805(agt)
PMEI: 106904009(agt)
GAF: 122842142(agt)
PPRL: 129359861(agt)
CVG: 107091346(agt)
CTUL: 119783797(agt)
GMU: 124859015(agt)
NFU: 107375970(agt)
KMR: 108245247(agt)
ALIM: 106513047(agt)
NWH: 119418955(agt)
AOCE: 111582735(agt)
MCEP: 125018573(agt)
CSEM: 103387045(agt)
POV: 109633337
SSEN: 122781633(agt)
HHIP: 117776010(agt)
HSP: 118118908(agt)
SMAU: 118283899(agt)
LCF: 108897315
SDU: 111235270(agt)
SLAL: 111663736(agt)
XGL: 120796154(agt)
HCQ: 109510241
SSCV: 125978777
SBIA: 133509782(agt)
PEE: 133410131(agt)
PTAO: 133485705(agt)
BPEC: 110156923(agt)
MALB: 109959264(agt)
BSPL: 114870387(agt)
SJO: 128372594(agt)
SASA: 100195417(agt)
STRU: 115201480(agt)
OTW: 112224539(agt)
OMY: 100136097(agt)
OGO: 124040264(agt)
ONE: 115144321(agt)
OKI: 109870483(agt)
OKE: 118402843(agt)
SALP: 111968013(agt)
SNH: 120029331(agt)
CCLU: 121547622(agt)
ELS: 105021210(agt)
SFM: 108932829(agt)
PKI: 111855087(agt)
AANG: 118217721 118221504(agt)
LOC: 102693842(agt)
PSPA: 121317159(agt)
ARUT: 117410777(agt)
PSEX: 120525701(agt)
LCM: 102362756(AGT)
CMK: 103187633(agt)
RTP: 109916839(agt)
CPLA: 122542897(agt)
HOC: 132807076(agt)
LERI: 129696957
 » show all
Reference
PMID:9331547
  Authors
Corvol P, Jeunemaitre X
  Title
Molecular genetics of human hypertension: role of angiotensinogen.
  Journal
Endocr Rev 18:662-77 (1997)
DOI:10.1210/edrv.18.5.0312
Reference
PMID:3579322
  Authors
Kunapuli SP, Benedict CR, Kumar A
  Title
Tissue specific hormonal regulation of the rat angiotensinogen gene expression.
  Journal
Arch Biochem Biophys 254:642-6 (1987)
DOI:10.1016/0003-9861(87)90148-2
  Sequence
[hsa:183]
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