KEGG   ORTHOLOGY: K10852
Entry
K10852                      KO                                     
Symbol
PENDE
Name
isopenicillin-N N-acyltransferase [EC:2.3.1.164]
Pathway
map00311  Penicillin and cephalosporin biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00672  Penicillin biosynthesis, aminoadipate + cycteine + valine => penicillin
Reaction
R06361  acyl-CoA:isopenicillin N N-acyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00311 Penicillin and cephalosporin biosynthesis
    K10852  PENDE; isopenicillin-N N-acyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K10852  PENDE; isopenicillin-N N-acyltransferase
   01008 Polyketide biosynthesis proteins
    K10852  PENDE; isopenicillin-N N-acyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.164  isopenicillin-N N-acyltransferase
     K10852  PENDE; isopenicillin-N N-acyltransferase
Peptidases and inhibitors [BR:ko01002]
 Cysteine peptidases
  Family C45
   K10852  PENDE; isopenicillin-N N-acyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
 Nonribosomal peptide tailoring proteins
  Others
   K10852  PENDE; isopenicillin-N N-acyltransferase
Other DBs
GO: 0050640
Genes
AMUS: LMH87_009794
ANI: ANIA_02623
AOR: AO090038000545
AFV: AFLA_009031
APUU: APUU_12362A
PCS: N7525_006406
ABE: ARB_02224
TVE: TRV_00551
Reference
PMID:2120195
  Authors
Tobin MB, Fleming MD, Skatrud PL, Miller JR
  Title
Molecular characterization of the acyl-coenzyme A:isopenicillin N acyltransferase gene (penDE) from Penicillium chrysogenum and Aspergillus nidulans and activity of recombinant enzyme in Escherichia coli.
  Journal
J Bacteriol 172:5908-14 (1990)
DOI:10.1128/JB.172.10.5908-5914.1990
  Sequence
[pcs:N7525_006406] [ani:ANIA_02623]
LinkDB

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