KEGG   ORTHOLOGY: K12676
Entry
K12676                      KO                                     
Symbol
pah
Name
proclavaminate amidinohydrolase [EC:3.5.3.22]
Pathway
map00331  Clavulanic acid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00674  Clavaminate biosynthesis, arginine + glyceraldehyde-3P => clavaminate
Reaction
R05357  amidinoproclavaminate amidinohydrolase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00331 Clavulanic acid biosynthesis
    K12676  pah; proclavaminate amidinohydrolase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.3  In linear amidines
    3.5.3.22  proclavaminate amidinohydrolase
     K12676  pah; proclavaminate amidinohydrolase
Other DBs
GO: 0033972
Genes
RAP: RHOA_4422
APAU: AMPC_01500(speB_2)
SANL: KZO11_35500(speB)
SFA: Sfla_0557
STRP: F750_6322
SCLF: BB341_07815 BB341_29475
SFK: KY5_8016c
SKA: CP970_43085(speB)
SVR: CP971_33675(speB)
SSPB: CP982_00550(speB)
SOV: QZH56_31605(speB)
SFIY: F0344_21140(speB)
KAB: B7C62_18895
KAU: B6264_26745
SVI: Svir_33400
MSIL: METEAL_21680(speB)
MSEA: METESE_19060(speB)
 » show all
Reference
PMID:8529893
  Authors
Hodgson JE, Fosberry AP, Rawlinson NS, Ross HN, Neal RJ, Arnell JC, Earl AJ, Lawlor EJ
  Title
Clavulanic acid biosynthesis in Streptomyces clavuligerus: gene cloning and characterization.
  Journal
Gene 166:49-55 (1995)
DOI:10.1016/0378-1119(95)00560-9
  Sequence
[sclf:BB341_07815]
Reference
PMID:7601835
  Authors
Wu TK, Busby RW, Houston TA, McIlwaine DB, Egan LA, Townsend CA
  Title
Identification, cloning, sequencing, and overexpression of the gene encoding proclavaminate amidino hydrolase and characterization of protein function in clavulanic acid biosynthesis.
  Journal
J Bacteriol 177:3714-20 (1995)
DOI:10.1128/JB.177.13.3714-3720.1995
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