KEGG ORTHOLOGY: K13365

ORTHOLOGY: K13365

Entry

K13365                      KO

Symbol

SLC9A3R1, NHERF1

Name

sodium/hydrogen exchange regulatory cofactor NHE-RF1

Pathway

map04530

Tight junction

map04928

Parathyroid hormone synthesis, secretion and action

map05130

Pathogenic Escherichia coli infection

map05165

Human papillomavirus infection

Disease

H00888

Nephrolithiasis/osteoporosis, hypophosphatemic

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    K13365  SLC9A3R1, NHERF1; sodium/hydrogen exchange regulatory cofactor NHE-RF1
09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    K13365  SLC9A3R1, NHERF1; sodium/hydrogen exchange regulatory cofactor NHE-RF1
09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K13365  SLC9A3R1, NHERF1; sodium/hydrogen exchange regulatory cofactor NHE-RF1
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K13365  SLC9A3R1, NHERF1; sodium/hydrogen exchange regulatory cofactor NHE-RF1
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K13365  SLC9A3R1, NHERF1; sodium/hydrogen exchange regulatory cofactor NHE-RF1
Transporters [BR:ko02000]
Other transporters
  Accessory factors involved in transport
   K13365  SLC9A3R1, NHERF1; sodium/hydrogen exchange regulatory cofactor NHE-RF1

Other DBs

TC:	8.A.24.1.1

Genes

HSA:	9368(NHERF1)

PTR:	454865(SLC9A3R1)

PPS:	100976426(SLC9A3R1)

PON:	100435096(SLC9A3R1)

NLE:	100606650(SLC9A3R1)

HMH:	116483462(NHERF1)

MCC:	703933(SLC9A3R1)

MCF:	101926883(SLC9A3R1)

MTHB:

126939247

MNI:	105469134(SLC9A3R1)

CSAB:

103243077(SLC9A3R1)

CATY:

105577765(SLC9A3R1)

PANU:

101018430(SLC9A3R1)

TGE:	112610088(SLC9A3R1)

MLEU:

105534579(SLC9A3R1)

RRO:	104681336(SLC9A3R1)

RBB:	108537346(SLC9A3R1)

TFN:	117066646(SLC9A3R1)

PTEH:

111542447(SLC9A3R1)

CANG:

105509876(SLC9A3R1)

CJC:	100415587(NHERF1)

SBQ:	101047062(SLC9A3R1)

CIMI:

108309381(SLC9A3R1)

CSYR:

103259736(SLC9A3R1)

MMUR:

105878907(SLC9A3R1)

LCAT:

123650759(SLC9A3R1)

PCOQ:

105824765(SLC9A3R1)

OGA:	100956465(SLC9A3R1)

MMU:	26941(Nherf1)

MCAL:

110305683(Slc9a3r1)

MPAH:

110331745(Slc9a3r1)

RNO:	59114(Nherf1)

MCOC:

116077263(Slc9a3r1)

ANU:	117711668(Slc9a3r1)

MUN:	110547585(Nherf1)

CGE:	100689081(Slc9a3r1)

MAUA:

101827137(Slc9a3r1)

PROB:

127218993(Nherf1)

PLEU:

114707030(Slc9a3r1)

MORG:

121436273(Slc9a3r1)

MFOT:

126486705 126500354

AAMP:

119811818(Slc9a3r1)

NGI:	103732759(Slc9a3r1)

HGL:	101697195(Slc9a3r1)

CPOC:

100724451(Slc9a3r1)

CCAN:

109683636(Slc9a3r1)

DORD:

106003209(Slc9a3r1)

DSP:	122094972(Slc9a3r1)

PLOP:

125365567(Slc9a3r1)

NCAR:

124980876

MMMA:

107157809(Slc9a3r1)

OCU:	100009196(SLC9A3R1)

OPI:	101516687(SLC9A3R1)

TUP:	102469825(SLC9A3R1)

GVR:	103603693(SLC9A3R1)

CFA:	483299(SLC9A3R1)

CLUD:

112672769(SLC9A3R1)

VVP:	112920772(SLC9A3R1)

VLG:	121473330(SLC9A3R1)

NPO:	129506904(NHERF1)

AML:	100475062(SLC9A3R1)

UMR:	103665925(SLC9A3R1)

UAH:	113244663(SLC9A3R1)

UAR:	123802926(SLC9A3R1)

ELK:

111160256

LLV:

125086648

MPUF:

101675183(SLC9A3R1)

MNP:	132003363(NHERF1)

MLK:	131816228(NHERF1)

NVS:	122906012(SLC9A3R1)

ORO:	101370861(SLC9A3R1)

EJU:	114216201(SLC9A3R1)

ZCA:	113939578(SLC9A3R1)

MLX:	118024297(SLC9A3R1)

NSU:	110577921(SLC9A3R1)

LWW:	102746429(SLC9A3R1)

FCA:	101091236(SLC9A3R1)

PYU:	121017878(SLC9A3R1)

PCOO:

112864716(SLC9A3R1)

PBG:	122485866(SLC9A3R1)

PVIV:

125151508(NHERF1)

LRUF:

124513442

PTG:	102964746(SLC9A3R1)

PPAD:

109276974(SLC9A3R1)

PUC:

125926398

AJU:

106987729

HHV:	120228189(SLC9A3R1)

BTA:	505242(NHERF1)

BOM:	102272422(SLC9A3R1)

BIU:	109573957(SLC9A3R1)

BBUB:

102411313(SLC9A3R1)

BBIS:

105000325(SLC9A3R1)

CHX:	106503247(SLC9A3R1)

OAS:	780527(NHERF1)

BTAX:

128064937(NHERF1)

ODA:	120866708(SLC9A3R1)

CCAD:

122434446(SLC9A3R1)

MBEZ:

129544748(NHERF1)

SSC:	100233201(SLC9A3R1)

CFR:	102515233(SLC9A3R1)

CBAI:

105065681(SLC9A3R1)

CDK:	105104615(SLC9A3R1)

VPC:	102527430(SLC9A3R1)

BACU:

102999840(SLC9A3R1)

BMUS:

118886852(SLC9A3R1)

LVE:	103087278(SLC9A3R1)

OOR:	101285712(NHERF1)

DLE:	111182862(SLC9A3R1)

PCAD:

102974343(NHERF1)

PSIU:

116746101(SLC9A3R1)

NASI:

112410456(SLC9A3R1)

ECB:	100052527(SLC9A3R1)

EPZ:	103546549(SLC9A3R1)

EAI:	106830264(SLC9A3R1)

MYB:	102238657(SLC9A3R1)

MYD:	102774436(SLC9A3R1)

MMYO:

118671166(SLC9A3R1)

MLF:	102441196(SLC9A3R1)

PKL:	118704605(SLC9A3R1)

EFUS:

103298313(NHERF1)

MNA:	107542931(SLC9A3R1)

DRO:	112298631(SLC9A3R1)

SHON:

119000943(SLC9A3R1)

AJM:	119065285(SLC9A3R1)

PDIC:

114502660(SLC9A3R1)

PHAS:

123817582(SLC9A3R1)

MMF:	118634755(SLC9A3R1)

PPAM:

129086502(NHERF1)

HAI:	109383704(SLC9A3R1)

RFQ:	117013327(SLC9A3R1)

PALE:

102884828(SLC9A3R1)

PGIG:

120600237(SLC9A3R1)

PVP:	105293331(SLC9A3R1)

RAY:	107503792(SLC9A3R1)

MJV:	108385957(SLC9A3R1)

TOD:	119230705(NHERF1)

SARA:

101546833(SLC9A3R1)

SETR:

126003452(NHERF1)

LAV:	100657092(SLC9A3R1)

TMU:

101340810

ETF:	101639119(SLC9A3R1)

DNM:	101442799(SLC9A3R1)

MDO:	100023596(SLC9A3R1)

GAS:	123244490(SLC9A3R1)

SHR:	100923352(SLC9A3R1)

AFZ:

127560501

PCW:	110219268(SLC9A3R1)

OAA:	100083069(SLC9A3R1)

GGA:	422108(SLC9A3R1)

PCOC:

116232378(SLC9A3R1)

MGP:	100539782(SLC9A3R1)

CJO:	107322366(SLC9A3R1)

TPAI:

128082977(NHERF1)

LMUT:

125702031(SLC9A3R1)

NMEL:

110407190(SLC9A3R1)

APLA:

106014700(SLC9A3R1)

ACYG:

106034617(SLC9A3R1)

CATA:

118253856(NHERF1)

AFUL:

116496506(SLC9A3R1)

TGU:	100221704(SLC9A3R1)

LSR:	110484321(SLC9A3R1)

SCAN:

103819828(SLC9A3R1)

PMOA:

120505697(SLC9A3R1)

OTC:	121338335(SLC9A3R1)

PRUF:

121363836(SLC9A3R1)

GFR:	102034520(SLC9A3R1)

FAB:	101812982(SLC9A3R1)

OMA:	130260325(NHERF1)

PHI:	102112878(SLC9A3R1)

PMAJ:

107212572(SLC9A3R1)

CCAE:

111937341(SLC9A3R1)

CCW:	104694295(SLC9A3R1)

CBRC:

103621794(SLC9A3R1)

ETL:	114070598(SLC9A3R1)

SVG:	106854313(SLC9A3R1)

MMEA:

130584409(NHERF1)

HRT:	120761017(NHERF1)

FPG:	101910898(SLC9A3R1)

FCH:	102046342(SLC9A3R1)

CLV:	102086214(SLC9A3R1)

EGZ:	104125335(SLC9A3R1)

NNI:	104020725(SLC9A3R1)

ACUN:

113486823(SLC9A3R1)

TALA:

116964064(SLC9A3R1)

AFOR:

103899263(SLC9A3R1)

ACHC:

115340989(SLC9A3R1)

HLE:	104839259(SLC9A3R1)

AGEN:

GCL:

CCRI:

MUI:

FGA:	104082806(SLC9A3R1)

LDI:

104348991

NNT:

104404245

SHAB:

115616654(SLC9A3R1)

DPUB:

104302381(SLC9A3R1)

CPEA:

104393261(SLC9A3R1)

CVF:	104282017(SLC9A3R1)

RTD:	128918039(NHERF1)

CUCA:

104062013(SLC9A3R1)

TEO:	104375061(SLC9A3R1)

BRHI:

104498229

AAM:	106500025(SLC9A3R1)

AROW:

112977806(SLC9A3R1)

NPD:	112953805(SLC9A3R1)

TGT:	104569083(SLC9A3R1)

DNE:	112982606(SLC9A3R1)

ASN:

102378850

AMJ:	102564111(SLC9A3R1)

CPOO:

109315039(SLC9A3R1)

GGN:	109297756(SLC9A3R1)

PSS:	102458961(SLC9A3R1)

CMY:	102929514(SLC9A3R1)

CCAY:

125621234(SLC9A3R1)

DCC:	119842965(SLC9A3R1)

CPIC:

101951153(SLC9A3R1)

TST:	117887380(SLC9A3R1)

CABI:

116827509(SLC9A3R1)

MRV:	120383213(SLC9A3R1)

ACS:	100567187(slc9a3r1)

ASAO:

132768649(NHERF1)

PVT:	110085799(SLC9A3R1)

SUND:

121921630(SLC9A3R1)

PBI:	103065588(SLC9A3R1)

PMUR:

114922167

CTIG:

120307757(SLC9A3R1)

TSR:	106553140(SLC9A3R1)

PGUT:

117660544(SLC9A3R1)

APRI:

131189476(NHERF1)

PTEX:

113437114(SLC9A3R1)

NSS:	113412041(SLC9A3R1)

VKO:	123035439(SLC9A3R1)

PMUA:

114592839(SLC9A3R1)

PRAF:

128407447(NHERF1)

ZVI:	118079799(SLC9A3R1)

HCG:	128346082(NHERF1)

GJA:	107110023(SLC9A3R1)

STOW:

125428239(SLC9A3R1)

EMC:	129328631(NHERF1)

XLA:	495828(slc9a3r1.L) 733155(slc9a3r1.S)

XTR:	448423(slc9a3r1)

NPR:	108785073(SLC9A3R1)

RTEM:

120918861

BBUF:

121003812(SLC9A3R1)

BGAR:

122940542(SLC9A3R1)

MUO:	115473399(SLC9A3R1)

GSH:	117368054(SLC9A3R1)

DRE:	100329719(slc9a3r1b) 327272(nherf1a)

SRX:	107722225 107743012 107748877 107755498

SANH:

107654589 107665734 107684064 107702487

SGH:	107548720 107565796 107565870 107581587

CCAR:

109053165 109062266 109084715

CAUA:

113046588 113052706 113055973 113064169 113070983 113111642

CGIB:

127944951 127953152 127968973 128025408

PTET:

122341524(slc9a3r1b) 122355546(slc9a3r1a)

LROH:

127159081(nherf1b) 127174221(nherf1a)

OMC:	131536421(nherf1b) 131551099(nherf1a)

PPRM:

120474648(slc9a3r1a) 120474954(slc9a3r1b)

RKG:	130085476(nherf1b) 130105439(nherf1a)

MAMB:

125255651(slc9a3r1a) 125266050(slc9a3r1b)

CIDE:

127508351 127523357

MASI:

127423054 127426868 127450379 127451167

TROS:

130561979(nherf1b) 130569642(nherf1a)

TDW:	130425564(nherf1b) 130439380(nherf1a)

MANU:

129420983(nherf1a) 129428156 129428587

IPU:	108273916(slc9a3r1a)

IFU:	128617315(nherf1a)

PHYP:

113527211(slc9a3r1)

SMEO:

124388574(slc9a3r1a)

TFD:	113662585(slc9a3r1a)

TVC:	132863539(nherf1a)

AMEX:

103032410 103047279

CMAO:

118809293(slc9a3r1a) 118821493(slc9a3r1b)

EEE:	113572816 113576831

CHAR:

105901738(slc9a3r1b)

TRU:	101067452 101076548(slc9a3r1)

TFS:	130514755(nherf1b) 130539006

TNG:	GSTEN00004202G001 GSTEN00021816G001

LCO:	104929514 104935519

NCC:	104942880(slc9a3r1)

TBEN:

117483620 117492064

CGOB:

115012379 115024367(slc9a3r1)

PGEO:

117439172 117450983(slc9a3r1b)

GACU:

117540966 117544124(slc9a3r1b)

EMAC:

134870908 134877925

ELY:	117247586 117268765(slc9a3r1b)

EFO:	125879195(slc9a3r1b) 125880921(slc9a3r1a)

PLEP:

121956509 121959264(slc9a3r1a)

SLUC:

116065539(slc9a3r1b) 116067460

ECRA:

117937158(slc9a3r1a) 117957520(slc9a3r1b)

ESP:	116671477 116703751

PFLV:

114548006(slc9a3r1) 114569885

GAT:	120819289(slc9a3r1a) 120827209(slc9a3r1b)

PPUG:

119212489(slc9a3r1a) 119220735(slc9a3r1b)

AFB:	129091584 129098756

CLUM:

117735046 117748497(slc9a3r1a)

PSWI:

130188232 130203646(nherf1a)

MSAM:

119886259(slc9a3r1b) 119916611

SCHU:

122867327

CUD:	121528933(slc9a3r1a) 121529615

ALAT:

119009347(slc9a3r1a) 119014740(slc9a3r1b)

MZE:	101475468 101485040

ONL:	100706235 100707955

OAU:	116314558(slc9a3r1b) 116330618(slc9a3r1a)

OLA:	101158858 101171366

OML:

112154630

CSAI:

133419392(nherf1a) 133421444

XMA:	102231714(slc9a3r1) 102238324

XCO:	114152357(slc9a3r1) 114160445

XHE:	116726619(slc9a3r1) 116736050

PRET:

103469117 103481903(slc9a3r1)

PFOR:

103144668 103152893 103153330

PLAI:

106957429 106958762(slc9a3r1)

PMEI:

106905385 106906908 106920640

GAF:	122822329 122823200

PPRL:

129363337 129377484

CVG:	107087437 107091463

CTUL:

119778616 119781688

GMU:	124863591 124864728 124874961(slc9a3r1a)

NFU:	107376688 107395593(slc9a3r1)

KMR:	108242914(slc9a3r1b) 108246416(slc9a3r1a)

ALIM:

106516488 106528777(slc9a3r1)

NWH:	119422189(slc9a3r1b) 119423343

AOCE:

111565368 111588299

MCEP:

124998303(slc9a3r1b) 125021967(slc9a3r1a)

CSEM:

103382195(slc9a3r1) 103393212

POV:	109626742(slc9a3r1) 109639496 109643752

SSEN:

122784878(slc9a3r1b)

HHIP:

117752528(slc9a3r1a) 117766744

HSP:	118100829(slc9a3r1a) 118123362(slc9a3r1b)

SMAU:

118287547(slc9a3r1a) 118288499(slc9a3r1b)

LCF:	108881036 108885270

SDU:	111220133 111230284

SLAL:

111651085 111651443(slc9a3r1)

XGL:	120787605(slc9a3r1b) 120794777(slc9a3r1a)

HCQ:	109514878(slc9a3r1)

SSCV:

125983684

SBIA:

133514282(nherf1b)

PEE:	133415118(nherf1b)

PTAO:

133465523(nherf1b)

BPEC:

110158205 110167907(slc9a3r1)

MALB:

109958903 109965135

BSPL:

114845494(nherf1a) 114860019(nherf1b)

SJO:	128378996(nherf1b) 128381769(nherf1a)

SASA:

100196730(slc9a3r1) 106589856(NHERF) 106601421 106606975

STRU:

115153488 115171413 115201667 115202291

OTW:	112229880 112234971 112234995 112257562(slc9a3r1a) 121843273(slc9a3r1b)

OMY:	110485193 110499432 110502759(slc9a3r1a) 110538536(slc9a3r1b)

OGO:	123999964 124015613 124025848 124038453

ONE:	115110680 115110683 115112996 115144448

OKI:	109889426 109892014 109898672 109899912

OKE:	118365602 118376790 118397918 118402718

SALP:

111968149 111978365 111981171

SNH:	120029486 120034193 120039320 120046682

CCLU:

121547720 121551102 121575614 121585155

ELS:	105008145(slc9a3r1) 105012909

SFM:	108936817 108940017

PKI:	111848569 111856754

AANG:

118216440(slc9a3r1a) 118216645

LOC:	102688109(slc9a3r1)

PSPA:

121295671 121296224

ARUT:

117423269(slc9a3r1b)

PSEX:

120517315(slc9a3r1b)

LCM:	102362773(SLC9A3R1)

CMK:

103175745

CPLA:

122562061

HOC:

132827642

LERI:

129708354(nherf1b)

BFO:

118428435

CIN:

100179793

SCLV:

120332410 120337393 120337394

SPU:	115918512 763547

SKO:

API:

DNX:

AGS:

RMD:

NLU:

TPAL:

TCF:

PPOI:

DSV:

RMP:	119180889 119182683

CSCU:

111637546

NAI:	NECAME_02642

HRO:	HELRODRAFT_193300

LGI:	LOTGIDRAFT_223723

PMAX:

RPHI:

LAK:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

Reference

PMID:9430655

Authors

Murthy A, Gonzalez-Agosti C, Cordero E, Pinney D, Candia C, Solomon F, Gusella J, Ramesh V

Title

NHE-RF, a regulatory cofactor for Na(+)-H+ exchange, is a common interactor for merlin and ERM (MERM) proteins.

Journal

J Biol Chem 273:1273-6 (1998)
DOI:10.1074/jbc.273.3.1273

Sequence

[hsa:9368]

LinkDB

DBGET integrated database retrieval system