KEGG ORTHOLOGY: K13718

ORTHOLOGY: K13718

Entry

K13718                      KO

Symbol

OTUD4

Name

OTU domain-containing protein 4 [EC:3.4.19.12]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K13718  OTUD4; OTU domain-containing protein 4
Enzymes [BR:ko01000]
3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.19  Omega peptidases
    3.4.19.12  ubiquitinyl hydrolase 1
     K13718  OTUD4; OTU domain-containing protein 4
Peptidases and inhibitors [BR:ko01002]
Cysteine peptidases
  Family C85
   K13718  OTUD4; OTU domain-containing protein 4

Other DBs

GO:

0004843

Genes

HSA:	54726(OTUD4)

PTR:	466922(OTUD4)

PPS:	100990144(OTUD4)

GGO:	101153212(OTUD4) 109029252

PON:	100431477(OTUD4)

NLE:	100605387(OTUD4)

HMH:	116464510(OTUD4)

MCC:	701837(OTUD4)

MCF:	101926732(OTUD4)

MTHB:

126955316

MNI:	105463409(OTUD4)

CSAB:

103236323(OTUD4)

CATY:

105580758(OTUD4)

PANU:

101016781(OTUD4)

TGE:	112624256(OTUD4)

MLEU:

105544585(OTUD4)

RRO:	104660722(OTUD4)

RBB:	108535493(OTUD4)

TFN:	117085975(OTUD4)

PTEH:

111552638(OTUD4)

CANG:

105522748(OTUD4)

CJC:	100403277(OTUD4)

SBQ:	101037579(OTUD4)

CIMI:

108308663(OTUD4)

CSYR:

103274041(OTUD4)

MMUR:

105881852(OTUD4)

LCAT:

123638460(OTUD4)

PCOQ:

105808982(OTUD4)

OGA:	100951352(OTUD4)

MMU:	73945(Otud4)

MCAL:

110299758(Otud4)

MPAH:

110337769(Otud4)

RNO:	307774(Otud4)

MCOC:

116069630(Otud4)

ANU:	117723161(Otud4)

MUN:	110547822(Otud4)

CGE:	100771576(Otud4)

MAUA:

101829359(Otud4)

PROB:

127237489(Otud4)

PLEU:

114701638(Otud4)

MORG:

121455726(Otud4)

MFOT:

126513243

AAMP:

119801828(Otud4)

NGI:	103729406(Otud4)

HGL:	101706252(Otud4)

CPOC:

100733347(Otud4)

CCAN:

109697631(Otud4)

DORD:

105995714(Otud4)

DSP:	122127173(Otud4)

PLOP:

125341427(Otud4)

NCAR:

124994611

MMMA:

107141243(Otud4)

OCU:	100341000 100341800 100353402

OPI:	101521806(OTUD4)

TUP:	102493601(OTUD4)

GVR:

103601513

CFA:	475455(OTUD4)

CLUD:

112654314(OTUD4)

VVP:	112934675(OTUD4)

VLG:	121481156(OTUD4)

NPO:	129516947(OTUD4)

AML:	100479320(OTUD4)

UMR:	103657990(OTUD4)

UAH:	113255723(OTUD4)

UAR:	123793243(OTUD4)

ELK:

111154210

LLV:

125093001

MPUF:

101686666(OTUD4)

MNP:	131999916(OTUD4)

MLK:	131832878(OTUD4)

NVS:	122889614(OTUD4)

ORO:	101381696(OTUD4)

EJU:	114208161(OTUD4)

ZCA:	113924267(OTUD4)

MLX:	118022277(OTUD4)

NSU:	110571266(OTUD4)

LWW:	102738720(OTUD4)

FCA:	101096147(OTUD4)

PYU:	121029015(OTUD4)

PCOO:

112858438(OTUD4)

PBG:	122475919(OTUD4)

PVIV:

125163708(OTUD4)

LRUF:

124520231

PTG:	102957243(OTUD4)

PPAD:

109249910(OTUD4)

PUC:

125923131

AJU:

106983449

HHV:	120226712(OTUD4)

BTA:	528907(OTUD4)

BOM:	102265618(OTUD4)

BIU:	109571043(OTUD4)

BBUB:

102415477(OTUD4)

BBIS:

104987988(OTUD4)

CHX:	102177268(OTUD4)

OAS:	101110451(OTUD4)

BTAX:

128062232(OTUD4)

ODA:	120870882(OTUD4)

CCAD:

122452012(OTUD4)

MBEZ:

129542897(OTUD4)

SSC:	100524693(OTUD4)

CFR:	102514082(OTUD4)

CBAI:

105068672(OTUD4)

CDK:	105091211(OTUD4)

VPC:	102530645(OTUD4)

BACU:

103002604(OTUD4)

BMUS:

118895658(OTUD4)

LVE:	103081901(OTUD4)

OOR:	101288616(OTUD4)

DLE:	111187704(OTUD4)

PCAD:

102995066(OTUD4)

PSIU:

116754186(OTUD4)

NASI:

112393734(OTUD4)

ECB:	100070999(OTUD4)

EPZ:	103547880(OTUD4)

EAI:	106829163(OTUD4)

MYB:	102241319(OTUD4)

MYD:	102769851(OTUD4)

MMYO:

118657733(OTUD4)

MLF:	102431823(OTUD4)

PKL:	118711395(OTUD4)

EFUS:

103288166(OTUD4)

MNA:	107532518(OTUD4)

DRO:	112312392(OTUD4)

SHON:

118995426(OTUD4)

AJM:	119061720(OTUD4)

PDIC:

114504239(OTUD4)

PHAS:

123813744(OTUD4)

MMF:	118615222(OTUD4)

PPAM:

129061998(OTUD4)

HAI:	109393110(OTUD4)

RFQ:	117037939(OTUD4)

PALE:

102879557(OTUD4)

PGIG:

120613330(OTUD4)

PVP:	105291559(OTUD4)

RAY:	107520345(OTUD4)

MJV:	108387423(OTUD4)

TOD:	119233683(OTUD4)

SARA:

101548216(OTUD4)

SETR:

126003678(OTUD4)

LAV:	100656430(OTUD4)

TMU:

101353749

ETF:	101655255(OTUD4)

DNM:	101432835(OTUD4)

MDO:	100026510(OTUD4)

GAS:	123251156(OTUD4)

SHR:	100923369(OTUD4)

AFZ:

127542113

PCW:	110202278(OTUD4)

OAA:	100082889(OTUD4)

GGA:	422463(OTUD4)

PCOC:

116226118(OTUD4)

MGP:	100545210(OTUD4)

CJO:	107313141(OTUD4)

TPAI:

128084413(OTUD4)

LMUT:

125692015(OTUD4)

NMEL:

110398079(OTUD4)

ACYG:

106032220(OTUD4)

CATA:

118249349(OTUD4)

AFUL:

116488783(OTUD4)

TGU:	100225453 116806608

LSR:	110480928(OTUD4)

SCAN:

103826073 115485309

PMOA:

120502816(OTUD4)

OTC:	121339927(OTUD4)

PRUF:

121365228(OTUD4)

GFR:	102043110(OTUD4)

FAB:	101806356(OTUD4)

OMA:	130252826(OTUD4)

PHI:	102113997(OTUD4)

PMAJ:

107203007(OTUD4)

CCAE:

111928833 111928935

CCW:

104697232

CBRC:

103622354(OTUD4)

ETL:	114068539(OTUD4)

ZAB:

102069631

ACHL:

103807381(OTUD4)

SVG:	106855693(OTUD4)

MMEA:

130579480(OTUD4)

HRT:	120753091(OTUD4)

FPG:	101919566(OTUD4)

FCH:	102059584 114016304

CLV:	102097803(OTUD4)

EGZ:	104130582(OTUD4)

NNI:	104015960(OTUD4)

PCRI:

104032725(OTUD4)

PLET:

104625757(OTUD4)

EHS:	104516905(OTUD4)

PCAO:

104039900(OTUD4)

ACUN:

113490478(OTUD4)

TALA:

104361156(OTUD4)

PADL:

103920886(OTUD4)

AFOR:

103899742(OTUD4)

ACHC:

115346595(OTUD4)

HALD:

104323230(OTUD4)

HLE:	104837069(OTUD4)

AGEN:

126044977

GCL:

127015453

CCRI:

104167274(OTUD4)

CSTI:

104550616(OTUD4)

CMAC:

104475625(OTUD4)

MUI:

104548240

BREG:

104630129(OTUD4)

FGA:

104070285

GSTE:

104251435

LDI:	104351906(OTUD4)

OHA:	104337002(OTUD4)

NNT:	104399862(OTUD4)

SHAB:

115610941

PGUU:

104463226(OTUD4)

ACAR:

104530671

CPEA:

104398784(OTUD4)

AVIT:

104268294(OTUD4)

CVF:	104291513(OTUD4)

RTD:	128910573(OTUD4)

CUCA:

104067514(OTUD4)

TEO:	104373047(OTUD4)

BRHI:

104495480(OTUD4)

AAM:	106492003(OTUD4)

AROW:

112976369(OTUD4)

NPD:	112950145(OTUD4)

TGT:	104580725(OTUD4)

DNE:

112986745

SCAM:

104153377(OTUD4)

ASN:	102374144(OTUD4)

AMJ:	102574733(OTUD4)

CPOO:

109309640(OTUD4)

GGN:	109301188(OTUD4)

PSS:	102461425(OTUD4)

CMY:	102929360(OTUD4)

CCAY:

125635363(OTUD4)

DCC:	119854857(OTUD4)

CPIC:

101943260(OTUD4)

TST:	117877787(OTUD4)

CABI:

116816017(OTUD4)

MRV:	120406229(OTUD4)

ACS:	100557695(otud4)

ASAO:

132776823(OTUD4)

PVT:	110073631(OTUD4)

SUND:

121931091(OTUD4)

PBI:	103052045(OTUD4)

PMUR:

107286196(OTUD4)

CTIG:

120306207(OTUD4)

TSR:	106548616(OTUD4)

PGUT:

117654624(OTUD4)

APRI:

131203395(OTUD4)

PTEX:

113434742(OTUD4)

NSS:

113412881

VKO:	123023871(OTUD4)

PMUA:

114604218 114604408

PRAF:

128421035(OTUD4)

ZVI:	118083720(OTUD4)

HCG:	128326194(OTUD4)

GJA:	107120270(OTUD4)

STOW:

125439748(OTUD4)

EMC:	129337056(OTUD4)

XLA:	108699484(otud4.L) 108706670(otud4.S)

XTR:	780053(otud4)

NPR:	108784241(OTUD4)

RTEM:

120919439(OTUD4)

BBUF:

120990008(OTUD4)

BGAR:

122943077(OTUD4)

MUO:	115461676(OTUD4)

GSH:	117358423(OTUD4)

DRE:	327127(otud4)

SRX:	107725717 107752195

SANH:

107653222 107694425

SGH:	107550163 107564414

CCAR:

109084302 109084369

CAUA:

113041219 113065822 113065874 113072512

CGIB:

127944435 128011393

PTET:

122332893(otud4)

LROH:

127154590(otud4)

OMC:	131531919(otud4)

PPRM:

120471142(otud4)

RKG:	130083751(otud4)

MAMB:

125260762(otud4)

CIDE:

127504466

MASI:

127418739 127419639

TROS:

130545283 130545423

TDW:	130409183(otud4)

MANU:

129431047(otud4)

IPU:

108275802

IFU:	128619184(otud4)

PHYP:

113530381(otud4)

SMEO:

124398939(otud4)

TFD:	113655418(otud4)

TVC:	132861896(otud4)

AMEX:

103025332(otud4)

CMAO:

118823009(otud4)

EEE:	113591016(otud4)

TRU:	101080243(otud4)

TFS:	130523362(otud4)

TNG:	GSTEN00008033G001

LCO:	104935546(otud4)

NCC:

104949362

GACU:

117538307

EMAC:

134876147(otud4)

ELY:	117245813(otud4)

EFO:	125883385(otud4)

SLUC:

116061823(otud4)

ECRA:

117935190(otud4)

PFLV:

114545970(otud4)

PPUG:

119221800(otud4)

AFB:	129093827(otud4)

CLUM:

117748092(otud4)

PSWI:

130212095(otud4)

MSAM:

119913218 119917678

CUD:	121504527(otud4)

ALAT:

119026816(otud4)

MZE:	101469286 112431396(otud4)

ONL:	100705536(otud4)

OAU:	116333525(otud4)

OLA:	101172195(otud4)

OML:	112156018(otud4)

CSAI:

133420936(otud4)

XMA:	102226430(otud4)

XCO:	114156868(otud4)

XHE:	116733316(otud4)

PRET:

103480833(otud4)

PFOR:

103151640(otud4)

PLAI:

106952656(otud4)

PMEI:

106928790(otud4)

GAF:	122820923(otud4)

PPRL:

129376468

CVG:	107087404(otud4)

CTUL:

119771358(otud4)

GMU:	124880841(otud4)

NFU:	107376809(otud4)

KMR:	108249153(otud4)

ALIM:

106514687(otud4)

NWH:	119414878(otud4)

AOCE:

111583544(otud4)

CSEM:

103389075(otud4)

POV:	109641486 109647123

SSEN:

122762524(otud4)

HHIP:

117751825(otud4)

HSP:	118102871(otud4)

SMAU:

118289000(otud4)

LCF:

108873739

SDU:	111239736(otud4)

SLAL:

111673178(otud4)

XGL:	120797407(otud4)

HCQ:	109507003(otud4)

SBIA:

133494801(otud4)

PEE:	133397678(otud4)

PTAO:

133472707(otud4)

MALB:

109951895(otud4)

BSPL:

114867815(otud4)

SJO:	128383591(otud4)

SASA:

106578201

STRU:

115195005(otud4)

OTW:	112239047(otud4)

OMY:	110531323(otud4)

OGO:	124008431(otud4)

OKE:	118380735(otud4)

SALP:

112073563(otud4)

SNH:	120030530(otud4)

ELS:	114828664(otud4)

SFM:	108936636(otud4)

PKI:	111833508(otud4)

AANG:

118232587(otud4)

LOC:

102685854

PSPA:

121296966 121321166

ARUT:

117409526 117421329(otud4)

LCM:	102347625(OTUD4)

CMK:	103182242(otud4)

RTP:

125482108

CPLA:

122554266(otud4)

HOC:	132820678(otud4)

LERI:

BBEL:

CIN:

SPU:

APLC:

DME:	Dmel_CG12743(otu) Dmel_CG3251(CG3251)

DER:	6543436 6549675

DSI:	Dsimw501_GD22696(Dsim_GD22696) Dsimw501_GD24569(Dsim_otu)

DYA:	Dyak_GE14692 Dyak_GE17448

DSR:	110175962 110179175

DPO:	6901339 6903251

DPE:	6595379 6598181

DMN:	108159126 108163482 117188639 117188641

DWI:

6641455

DGR:

6565439

DMO:	Dmoj_GI14856

DAZ:

DNV:

DHE:

CCAT:

BOD:

BDR:

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

ACOZ:

AARA:

ASTE:

AAG:

AALB:

109405532 109405671 115257260

CPII:

CNS:

BCOO:

AME:

BIM:

BTER:

CCAL:

OBB:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

VVE:

NVI:

CSOL:

MDL:

DPA:

ATD:

NVL:

OTU:

BMOR:

100532747(otu)

BMAN:

114251527

MSEX:

115445935

DPL:	KGM_209975

BANY:

MJU:

PMAC:

PPOT:

PXU:

PRAP:

ZCE:

AAGE:

HAW:	110372165 135117066

HZE:

TNL:

SLIU:

OFU:

PXY:

DNX:

AGS:

RMD:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

PHU:	Phum_PHUM492030

TPAL:

117652882

ZNE:

110841448

DPX:	DAPPUDRAFT_299567

PVM:

PJA:

PCHN:

HAME:

PCLA:

PTRU:

CSCU:

LGI:	LOTGIDRAFT_165606

HRF:

HRJ:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

DGT:

XEN:

HMG:

AQU:

ACAN:

Reference

PMID:1737618

Authors

Steinhauer WR, Kalfayan LJ

Title

A specific ovarian tumor protein isoform is required for efficient differentiation of germ cells in Drosophila oogenesis.

Journal

Genes Dev 6:233-43 (1992)
DOI:10.1101/gad.6.2.233

Sequence

[dme:Dmel_CG12743]

Reference

PMID:23827681

Authors

Mevissen TE, Hospenthal MK, Geurink PP, Elliott PR, Akutsu M, Arnaudo N, Ekkebus R, Kulathu Y, Wauer T, El Oualid F, Freund SM, Ovaa H, Komander D

Title

OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis.

Journal

Cell 154:169-84 (2013)
DOI:10.1016/j.cell.2013.05.046

Sequence

[hsa:54726]

LinkDB

DBGET integrated database retrieval system