KEGG ORTHOLOGY: K13857

ORTHOLOGY: K13857

Entry

K13857                      KO

Symbol

SLC4A5, NBC4

Name

solute carrier family 4 (sodium bicarbonate cotransporter), member 5

Pathway

map04976

Bile secretion

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    K13857  SLC4A5, NBC4; solute carrier family 4 (sodium bicarbonate cotransporter), member 5
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K13857  SLC4A5, NBC4; solute carrier family 4 (sodium bicarbonate cotransporter), member 5
   04147 Exosome
    K13857  SLC4A5, NBC4; solute carrier family 4 (sodium bicarbonate cotransporter), member 5
Transporters [BR:ko02000]
Solute carrier family (SLC)
  SLC4: Bicarbonate transporter
   K13857  SLC4A5, NBC4; solute carrier family 4 (sodium bicarbonate cotransporter), member 5
Exosome [BR:ko04147]
Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K13857  SLC4A5, NBC4; solute carrier family 4 (sodium bicarbonate cotransporter), member 5

Other DBs

GO:

0008510

TC:

2.A.31.2

Genes

HSA:	57835(SLC4A5)

PTR:	470408(SLC4A5)

PPS:	100993877(SLC4A5)

GGO:	101141818(SLC4A5)

PON:	100438431(SLC4A5)

NLE:	100584396(SLC4A5)

HMH:	116483871(SLC4A5)

MCC:	715025(SLC4A5)

MCF:	102141597(SLC4A5)

MTHB:

126934010

MNI:	105465287(SLC4A5)

CSAB:

103220036(SLC4A5)

CATY:

105596857(SLC4A5)

PANU:

101014941

TGE:	112604726(SLC4A5)

MLEU:

105540185(SLC4A5)

RRO:	104674808(SLC4A5)

RBB:	108520670(SLC4A5)

TFN:	117062047(SLC4A5)

PTEH:

111523401(SLC4A5)

CANG:

105514590(SLC4A5)

CJC:	100388030(SLC4A5)

SBQ:	101054439(SLC4A5)

CIMI:

108289298(SLC4A5)

CSYR:

103266736(SLC4A5)

MMUR:

105884593(SLC4A5)

LCAT:

123637070(SLC4A5)

PCOQ:

105821495(SLC4A5)

OGA:	100943889(SLC4A5)

MMU:	232156(Slc4a5)

MCAL:

110295879(Slc4a5)

MPAH:

110317402(Slc4a5)

RNO:	297386(Slc4a5)

MCOC:

116099134(Slc4a5)

ANU:	117714861(Slc4a5)

MUN:	110559327(Slc4a5)

CGE:	100771517(Slc4a5)

MAUA:

101843149(Slc4a5)

PROB:

127235812(Slc4a5)

PLEU:

114694413(Slc4a5)

MORG:

121466430(Slc4a5)

MFOT:

126515350

AAMP:

119807178(Slc4a5)

NGI:	103727001(Slc4a5)

HGL:	101705255(Slc4a5)

CPOC:

100714846(Slc4a5)

CCAN:

109676645(Slc4a5)

DORD:

105999580(Slc4a5)

DSP:	122125144(Slc4a5)

PLOP:

125356361(Slc4a5)

NCAR:

124962957

MMMA:

107154213(Slc4a5)

OCU:

100347641

OPI:	101534002(SLC4A5)

TUP:	102475514(SLC4A5)

GVR:	103605418(SLC4A5)

CFA:	612275(SLC4A5)

CLUD:

112664236(SLC4A5)

VVP:	112916727(SLC4A5)

VLG:	121490572(SLC4A5)

NPO:	129501335(SLC4A5)

AML:	100479737(SLC4A5)

UMR:	103671830(SLC4A5)

UAH:	113243796(SLC4A5)

UAR:	123786131(SLC4A5)

ELK:

111147980

LLV:

125108919

MPUF:

101672487(SLC4A5)

MNP:	132021438(SLC4A5)

MLK:	131840319(SLC4A5)

NVS:	122915001(SLC4A5)

ORO:	101375841(SLC4A5)

EJU:	114218946(SLC4A5)

ZCA:	113937925(SLC4A5)

MLX:	118007959(SLC4A5)

NSU:	110588690(SLC4A5)

LWW:	102726407(SLC4A5)

FCA:	101084098(SLC4A5)

PYU:

121019228

PCOO:

112868885(SLC4A5)

PBG:	122497030(SLC4A5)

PVIV:

125162719(SLC4A5)

LRUF:

124504215

PTG:	102961396(SLC4A5)

PPAD:

109263054(SLC4A5)

PUC:

125937123

AJU:

106988573

HHV:	120237015(SLC4A5)

BTA:	100297538(SLC4A5)

BOM:	102279361(SLC4A5)

BIU:	109565919(SLC4A5)

BBUB:

102395891(SLC4A5)

BBIS:

104980992(SLC4A5)

CHX:	102183881(SLC4A5)

OAS:	101105902(SLC4A5)

BTAX:

128056715(SLC4A5)

ODA:	120851235(SLC4A5)

CCAD:

122441492(SLC4A5)

MBEZ:

129539333(SLC4A5)

SSC:	100620628(SLC4A5)

CFR:	102522605(SLC4A5)

CBAI:

105066982(SLC4A5)

CDK:	105096570(SLC4A5)

VPC:	102542786(SLC4A5)

BACU:

103000129(SLC4A5)

BMUS:

118906214(SLC4A5)

LVE:	103080314(SLC4A5)

OOR:	101271534(SLC4A5)

DLE:	111169133(SLC4A5)

PCAD:

102977333(SLC4A5)

PSIU:

116764226(SLC4A5)

NASI:

112413639(SLC4A5)

ECB:	100069223(SLC4A5)

EPZ:	103564985(SLC4A5)

EAI:	106823851(SLC4A5)

MYB:	102257933(SLC4A5)

MYD:	102754513(SLC4A5)

MMYO:

118668840(SLC4A5)

MLF:	102435142(SLC4A5)

PKL:	118717555(SLC4A5)

EFUS:

103291408(SLC4A5)

MNA:	107529262(SLC4A5)

DRO:	112303008(SLC4A5)

SHON:

119000083(SLC4A5)

AJM:	119038409(SLC4A5)

PDIC:

114498522(SLC4A5)

PHAS:

123811403(SLC4A5)

MMF:	118630676(SLC4A5)

PPAM:

129086853(SLC4A5)

HAI:	109371224(SLC4A5)

RFQ:	117033401(SLC4A5)

PALE:

102885219(SLC4A5)

PGIG:

120594385(SLC4A5)

PVP:	105290774(SLC4A5)

RAY:	107502904(SLC4A5)

MJV:	108402281(SLC4A5)

TOD:	119259085(SLC4A5)

SARA:

101558257(SLC4A5)

SETR:

126023962(SLC4A5)

LAV:	100672155(SLC4A5)

TMU:

101348815

ETF:	101655912(SLC4A5)

DNM:	101438069(SLC4A5)

MDO:	100024265(SLC4A5)

GAS:	123233068(SLC4A5)

SHR:	100917647(SLC4A5)

AFZ:

127547315

PCW:	110222648(SLC4A5)

OAA:	100090321(SLC4A5)

GGA:	425261(SLC4A5)

PCOC:

116234501(SLC4A5)

MGP:	100538833(SLC4A5)

CJO:	107323668(SLC4A5)

TPAI:

128071848(SLC4A5)

LMUT:

125685162(SLC4A5)

NMEL:

110387223(SLC4A5)

APLA:

119713565(SLC4A5)

ACYG:

106047655(SLC4A5)

CATA:

118259343(SLC4A5)

AFUL:

116499380(SLC4A5)

TGU:	100219965(SLC4A5)

LSR:	110480189(SLC4A5)

SCAN:

103824668(SLC4A5)

PMOA:

120499128(SLC4A5)

OTC:	121336007(SLC4A5)

PRUF:

121355598(SLC4A5)

GFR:	102034816(SLC4A5)

FAB:	101815490(SLC4A5)

OMA:	130261913(SLC4A5)

PHI:	102104673(SLC4A5)

PMAJ:

107199104

CCAE:

111938874(SLC4A5)

CCW:	104683767(SLC4A5)

CBRC:

103622618(SLC4A5)

ETL:	114070889(SLC4A5)

ACHL:

103804525(SLC4A5)

SVG:	106862869(SLC4A5)

MMEA:

130586953

HRT:	120764001(SLC4A5)

FPG:	101914098(SLC4A5)

FCH:	102045688(SLC4A5)

CLV:	102087695(SLC4A5)

EGZ:	104130379(SLC4A5)

PCRI:

104029425(SLC4A5)

EHS:	104511919(SLC4A5)

PCAO:

104050744

ACUN:

113488112

TALA:

104361408(SLC4A5)

PADL:

103917168(SLC4A5)

AFOR:

103903697(SLC4A5)

ACHC:

115350460(SLC4A5)

HALD:

104321287(SLC4A5)

HLE:	104829016(SLC4A5)

AGEN:

126051736

GCL:

127025373

CMAC:

104486459(SLC4A5)

BREG:

104637905(SLC4A5)

FGA:	104074612(SLC4A5)

LDI:

104348408

OHA:	104338079(SLC4A5)

NNT:	104405972(SLC4A5)

SHAB:

115618517(SLC4A5)

DPUB:

104297833(SLC4A5)

PGUU:

104472051

CPEA:

104394350(SLC4A5)

CVF:	104281774(SLC4A5)

RTD:	128900128(SLC4A5)

CUCA:

104067020(SLC4A5)

TEO:	104376180(SLC4A5)

BRHI:

104494451(SLC4A5)

AAM:	106484146 106498063

AROW:

112975334(SLC4A5)

NPD:	112950585(SLC4A5)

TGT:	104580415(SLC4A5)

DNE:	112993856(SLC4A5)

SCAM:

104150774(SLC4A5)

ASN:	102379950(SLC4A5)

AMJ:	102576439(SLC4A5)

CPOO:

109317356(SLC4A5)

GGN:	109295503(SLC4A5)

PSS:	102448268(SLC4A5)

CMY:	102945669(SLC4A5)

CCAY:

125626364(SLC4A5)

DCC:	119848607(SLC4A5)

CPIC:

101931632(SLC4A5)

TST:	117872893(SLC4A5)

CABI:

116821201(SLC4A5)

MRV:	120397398(SLC4A5)

ACS:

100563636

ASAO:

132782372(SLC4A5)

PVT:	110072090(SLC4A5)

SUND:

121934315(SLC4A5)

PBI:	103051739(SLC4A5)

PMUR:

107283232(SLC4A5)

CTIG:

120299358(SLC4A5)

TSR:	106544035(SLC4A5)

PGUT:

117673330(SLC4A5)

APRI:

131204053(SLC4A5)

PTEX:

113445767(SLC4A5)

NSS:	113423395(SLC4A5)

VKO:	123016774(SLC4A5)

PMUA:

114602654(SLC4A5)

PRAF:

128420064(SLC4A5)

ZVI:	118086869(SLC4A5)

HCG:	128333756(SLC4A5)

GJA:	107118733(SLC4A5)

STOW:

125442050(SLC4A5)

EMC:	129342037(SLC4A5)

XLA:	108710312(slc4a5.L)

XTR:	100494100(slc4a5)

NPR:	108793887(SLC4A5)

RTEM:

120930248 120931051(SLC4A5)

BBUF:

120987187(SLC4A5)

BGAR:

122929524(SLC4A5)

MUO:	115469294(SLC4A5)

GSH:	117362499(SLC4A5)

DRE:	100006379(slc4a5) 559268(si:ch211-48m9.1)

SRX:	107706806 107709849 107721547 107741653

SANH:

107656495 107673401 107689609

SGH:	107567746 107587309 107588954 107595028

CCAR:

109081111

CAUA:

113069974 113079333 113110328

CGIB:

127958233 127966852 128009568

PTET:

122333761(slc4a5b) 122345751(slc4a5a)

LROH:

127165573(slc4a5a) 127172316(slc4a5b)

OMC:	131540295(slc4a5a) 131547888(slc4a5b)

PPRM:

120469921(slc4a5a) 120482551(slc4a5b)

RKG:	130089844(slc4a5a) 130094912(slc4a5b)

MAMB:

125262396(slc4a5b) 125266519(slc4a5a)

CIDE:

127513669 127520188

MASI:

127429159 127432364 127432562 127433863

TROS:

130545971(slc4a5b) 130567997(slc4a5a)

TDW:	130411623(slc4a5b) 130419223(slc4a5a)

MANU:

129440114(slc4a5a) 129446470(slc4a5b)

IPU:	108255867(slc4a5a) 108276580(slc4a5b)

IFU:	128620283(slc4a5b) 128625712(slc4a5a)

PHYP:

113542561 113544904

SMEO:

124380818(slc4a5a) 124393494(slc4a5b)

TFD:	113638478(slc4a5b) 113638960(slc4a5a)

TVC:	132854900(slc4a5a) 132863343(slc4a5b)

AMEX:

103038731 103042590

CMAO:

118824430(slc4a5b) 118827483(slc4a5a)

EEE:	113583909 113589570

CHAR:

105889877(slc4a5a) 105904677(slc4a5b)

TRU:	101071760 101072168

TFS:	130517202(slc4a5b) 130526248(slc4a5a)

TNG:	GSTEN00025388G001 GSTEN00034894G001

LCO:	104938766 109139920

TBEN:

117468668 117480859(slc4a5a)

CGOB:

115013463 115016446

PGEO:

117452649(slc4a5a)

GACU:

117536290(slc4a5a)

EMAC:

134868503(slc4a5b) 134873086(slc4a5a)

ELY:	117252910(slc4a5a) 117269623(slc4a5b)

EFO:	125889998(slc4a5a) 125906328(slc4a5b)

PLEP:

121943956(slc4a5a)

SLUC:

116041773(slc4a5b) 116047652(slc4a5a)

ECRA:

117944661(slc4a5a) 117959734

ESP:	116686199 116689516

PFLV:

114555340 114571048

GAT:	120830200(slc4a5a)

PPUG:

119224425(slc4a5a) 119226658(slc4a5b)

AFB:	129101623(slc4a5a) 129102879(slc4a5b)

CLUM:

117735871(slc4a5a) 117740686(slc4a5b)

PSWI:

130197442(slc4a5a) 130205527

MSAM:

119891426(slc4a5a) 119914969 119915080(slc4a5b)

SCHU:

122865668 122877024(slc4a5a)

CUD:	121509779(slc4a5a) 121525355(slc4a5b)

ALAT:

119019552(slc4a5a) 119030448(slc4a5b)

MZE:	101470466 101477060

ONL:	100700344 100703988

OAU:	116321089(slc4a5a) 116329326(slc4a5b)

OLA:	101162225 101171498

OML:	112148833(slc4a5a) 112162984(slc4a5b)

CSAI:

133451447(slc4a5a) 133455149(slc4a5b)

XMA:	102219504 102223050

XCO:	114150209 114154324

XHE:	116724727 116730214

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122819247(slc4a5b) 122826256(slc4a5a)

PPRL:

129373020(slc4a5a) 129379776(slc4a5b)

CVG:	107101937 107102242(slc4a5)

CTUL:

119781488(slc4a5a) 119795963(slc4a5b)

GMU:	124872671(slc4a5b) 124877602(slc4a5a)

NFU:	107393817(slc4a5) 107395321

KMR:	108245384(slc4a5b) 108246431(slc4a5a)

ALIM:

106521938 106526085

NWH:	119412955(slc4a5a) 119424939(slc4a5b)

AOCE:

111574432 111577488

MCEP:

124996463(slc4a5b) 125012573(slc4a5a)

CSEM:

103389646 103397421(slc4a5)

POV:	109626033 109633668

SSEN:

122758313 122769857(slc4a5a)

HHIP:

117768209(slc4a5a) 117771879(slc4a5b)

HSP:	118098129(slc4a5b) 118115390(slc4a5a)

SMAU:

118300652(slc4a5b) 118314535(slc4a5a)

LCF:	108878044 108891291 108895500(slc4a5b)

SDU:	111226170(slc4a5) 111239671

SLAL:

111648002 111659483

XGL:	120805119(slc4a5a) 120806362(slc4a5b)

HCQ:	109525055 109527912

SSCV:

125979476 125994290

SBIA:

133490850 133500022(slc4a5a)

PEE:	133400336(slc4a5a) 133413365(slc4a5b)

PTAO:

133474747(slc4a5a) 133490169(slc4a5b)

BPEC:

110163291(slc4a5) 110166695

MALB:

109974745

BSPL:

114862428(slc4a5a) 114866496(slc4a5b)

SJO:	128365471(slc4a5a) 128379909

SASA:

106562986 106568526 106580514 106585121

STRU:

115159783 115164277 115199651 115203874

OTW:	112219923 112231497 112248670 112266094

OMY:	110509317 110522819 110526893(slc4a5a) 110535095

OGO:	124007420 124036500 124049128

ONE:	115101060 115111790 115140692

OKI:	109868818 109873929 109880103 109894932

OKE:	118357878 118373301 118385571 118393411

SALP:

111957560 111974357

SNH:	120021857 120025853 120051470 120062912

CCLU:

121530667 121541505 121582689 121585040

ELS:	105015229 105029382

SFM:	108930029 108940366 114910715

PKI:	111848581(slc4a5) 111851460

AANG:

118213162(slc4a5b) 118237211(slc4a5a)

LOC:	102682547(slc4a5)

PSPA:

121303199

ARUT:

117397864 117966474

PSEX:

120538869(slc4a5a)

LCM:

RTP:

CPLA:

HOC:

LERI:

TCF:

Reference

PMID:18588858

Authors

Millar ID, Brown PD

Title

NBCe2 exhibits a 3 HCO3(-):1 Na+ stoichiometry in mouse choroid plexus epithelial cells.

Journal

Biochem Biophys Res Commun 373:550-4 (2008)
DOI:10.1016/j.bbrc.2008.06.053

Reference

PMID:23589833

Authors

Parker MD, Boron WF

Title

The divergence, actions, roles, and relatives of sodium-coupled bicarbonate transporters.

Journal

Physiol Rev 93:803-959 (2013)
DOI:10.1152/physrev.00023.2012

Sequence

[hsa:57835]

LinkDB

DBGET integrated database retrieval system