KEGG   ORTHOLOGY: K14520
Entry
K14520                      KO                                     
Symbol
hapE
Name
4-hydroxyacetophenone monooxygenase [EC:1.14.13.84]
Pathway
map00363  Bisphenol degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Reaction
R06892  (4-hydroxyphenyl)ethan-1-one,NADPH:oxygen oxidoreductase (ester-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00363 Bisphenol degradation
    K14520  hapE; 4-hydroxyacetophenone monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.84  4-hydroxyacetophenone monooxygenase
     K14520  hapE; 4-hydroxyacetophenone monooxygenase
Other DBs
GO: 0033767
Genes
PALK: PSAKL28_30880
GAG: Glaag_3898
GPS: C427_5372
HJA: BST95_01710
HALC: EY643_18055
CUK: KB879_33605
BXE: Bxe_C0316
BXB: DR64_8118
BGE: BC1002_5820
PVE: UC34_06840
BHZ: ACR54_00614(hapE_3)
BPDZ: BBN53_18555
AXY: AXYL_05757
ADY: HLG70_25065
APES: FOC84_16990
AAEG: RA224_03845
HYB: Q5W_23445
DIH: G7047_24405
MESO: BSQ44_24815
CHEA: PVE73_18625
RHI: NGR_a03290
SAME: SAMCFNEI73_pB0414
ESJ: SJ05684_a39130
REL: REMIM1_PE00364
REI: IE4771_PB00135
RTR: RTCIAT899_PB00970
RGA: RGR602_PB00162
RJG: CCGE525_34750
BJA: bll3180(bll3180)
BJU: BJ6T_65720
BJP: RN69_31860
BRS: S23_48170
BRC: BCCGELA001_14335
BIC: LMTR13_10065
BRK: CWS35_32470
BOT: CIT37_37580
BRQ: CIT40_10485
BGQ: X265_25110
BGZ: XH91_23220
BSYM: CIT39_09530
BBET: F8237_04135
BARH: WN72_17480
BVZ: BRAD3257_1812
BEL: BE61_38490
BDG: LPJ38_18855
BSEP: HAP48_0048135
BQB: J4P68_0007355
BBAN: J4G43_018415
BAUT: QA635_14830
BBRA: QA636_14590
BGK: IC762_25630
BCOU: IC761_23575
BPAH: QA639_30255
BXN: I3J27_12310
BROS: QUH67_11180
BRAZ: LRP30_14055
MMED: Mame_02139(hapE)
RBM: TEF_09540 TEF_14660
PZU: PHZ_c1807
PHB: HYN04_07140
SMED: JNX03_16175
RID: RIdsm_01107(hapE_3)
NAR: Saro_2452
NPN: JI59_09905 JI59_12755 JI59_17720 JI59_21965
NOV: TQ38_027485 TQ38_027690
NOT: C7W88_20535
NOR: FA702_19610
NOG: GKE62_01765
SPHP: LH20_19445
STER: AOA14_07210
SWI: Swit_2012
SPHD: HY78_15455
SPHM: G432_19880
SMY: BJP26_18750
SPKC: KC8_02285 KC8_02340
SJP: SJA_C2-05090
SINB: SIDU_10910
SCH: Sphch_3468
SPMI: K663_17836 K663_17946 K663_18141 K663_19768
SPHB: EP837_01273(hapE) EP837_01276 EP837_03238 EP837_03267 EP837_03277 EP837_03339 EP837_03509
SPHT: K426_23414
SPPH: KFK14_08115
SPHJ: BSL82_08780
PALG: HFP57_16470
SMIC: SmB9_21780 SmB9_37040
SAND: H3309_16645
POQ: KZX46_02635 KZX46_17875
PMEA: KTC28_16080
AEP: AMC99_02079
ALH: G6N82_11870
EFV: CHH26_10020
ERR: DVR09_13385
NTD: EGO55_02615 EGO55_04725 EGO55_13890 EGO55_14155 EGO55_18115
TMO: TMO_b0525
MPA: MAP_1620
MAO: MAP4_2219
MAVI: RC58_11040
MAVU: RE97_11050
MAV: MAV_2805
MIT: OCO_26400
MIA: OCU_26250
MID: MIP_04049
MYO: OEM_24870
MCHI: AN480_10590 AN480_13895
MIR: OCQ_24960
MMAL: CKJ54_11925
MMAN: MMAN_12600
MSA: Mycsm_03363
MMI: MMAR_2622 MMAR_2789
MMAE: MMARE11_25410 MMARE11_27110
MLI: MULP_02355
MPSE: MPSD_28800
MSHO: MSHO_39150 MSHO_41990
MMC: Mmcs_1518 Mmcs_2740
MKM: Mkms_1541 Mkms_2784
MJL: Mjls_2770
MMM: W7S_12815
MKN: MKAN_00815
MYV: G155_01790
MYE: AB431_01805
MDX: BTO20_34235
MSHG: MSG_02684 MSG_04454
MFJ: MFLOJ_05450 MFLOJ_51620 MFLOJ_54900
MSTO: MSTO_06750 MSTO_59330
MSIM: MSIM_50750
MSAK: MSAS_07860
MKU: I2456_13765
MLW: MJO58_14125 MJO58_19375
MXE: MYXE_38750 MYXE_42320
MNV: MNVI_26500
MPAG: C0J29_01040 C0J29_16070
MNM: MNVM_28240
MGOR: H0P51_00695 H0P51_09335 H0P51_15105
MCOO: MCOO_43040
MBAI: MB901379_02580(hapE_5)
MSEO: MSEO_14970
MHEK: JMUB5695_03800
MGAU: MGALJ_16320
MLJ: MLAC_18560
MBRD: MBRA_05320
MSHJ: MSHI_13020
MMAM: K3U93_12890 K3U93_16480
MSPG: F6B93_11555 F6B93_12080
MOT: LTS72_10260
MPAA: MKK62_19500 MKK62_25885
MKY: IWGMT90018_29320 IWGMT90018_35310 IWGMT90018_47580
MADI: A7U43_00820 A7U43_19685
MWU: PT015_22885
MVA: Mvan_1842
MGI: Mflv_4506
MSP: Mspyr1_39050
MCB: Mycch_1506
MNE: D174_03215
MYN: MyAD_03140
MFT: XA26_03850
MPHL: MPHLCCUG_01020(hapE_2)
MVQ: MYVA_1697 MYVA_4982
MLL: B1R94_01420 B1R94_12415
MRH: MycrhN_4918
MTHN: 4412656_00667(hapE_1)
MHAS: MHAS_00653(hapE_1)
MDU: MDUV_26540
MCHT: MCHIJ_02010 MCHIJ_02120 MCHIJ_08790
MAUU: NCTC10437_01662(hapE_4) NCTC10437_01669(hapE_5)
MMAG: MMAD_29640
MMOR: MMOR_00710 MMOR_10050 MMOR_33780 MMOR_47920
MFX: MFAL_09770 MFAL_26200
MAIC: MAIC_53440
MIJ: MINS_06790 MINS_26620
MALV: MALV_32190
MTY: MTOK_12030
MPSC: MPSYJ_47990
MARZ: MARA_09020
MGAD: MGAD_08510
MHEV: MHEL_19100 MHEL_59170
MSAR: MSAR_18520
MANY: MANY_43550
MAUB: MAUB_06770
MPOF: MPOR_21690
MPHU: MPHO_05910
MMUC: C1S78_015375
MMAT: MMAGJ_17560
MBOK: MBOE_16070
MFG: K6L26_29615
MSEI: MSEDJ_42750
MCEE: MCEL_41620
MMON: EWR22_07725 EWR22_14555
MHOL: K3U96_00470 K3U96_07055 K3U96_12435
MSEN: K3U95_01840
MPAE: K0O64_01410
MRF: MJO55_08255
MDF: K0O62_02210 K0O62_05035 K0O62_11570
MCRO: MI149_01945
MGRO: FZ046_20310
MPAK: MIU77_08125
MCHE: BB28_00510
MSAL: DSM43276_00081(hapE_2)
MJD: JDM601_3248
MTER: 4434518_03234(hapE_6)
MMIN: MMIN_09430
MHIB: MHIB_26590
MHER: K3U94_18290
MVM: MJO54_18455
CCYC: SCMU_01920 SCMU_38690
NFA: NFA_33700
NFR: ERS450000_00683(hapE_3)
NNO: NONO_c26450 NONO_c26620 NONO_c26820 NONO_c27210
NOZ: DMB37_03490
RHA: RHA1_ro05396
REY: O5Y_27880
RQI: C1M55_29730
ROP: ROP_25260
RHB: NY08_34
RFA: A3L23_03397(hapE_2)
RHS: A3Q41_04847(hapE_2)
RRZ: CS378_11525
RHU: A3Q40_00667(hapE_1)
RHOD: AOT96_09385
RCR: NCTC10994_03316(hapE_4)
RKO: JWS14_03735 JWS14_13900 JWS14_43780 JWS14_44120 JWS14_44420
ROZ: CBI38_08630 CBI38_34625
RPSK: JWS13_12455 JWS13_31690
RANT: RHODO2019_18180
REQ: REQ_45280
GOR: KTR9_0546 KTR9_2191 KTR9_3188
GTA: BCM27_04875 BCM27_11715 BCM27_16285 BCM27_19035
GRU: GCWB2_13960(hapE4)
GOM: D7316_04266(hapE_1) D7316_04655(hapE_2)
GAV: C5O27_14130
GOD: GKZ92_12830
GPD: GII33_20030
GJI: H1R19_00410 H1R19_10915 H1R19_19295
GHN: MVF96_11115
GAMI: IHQ52_16570
GMG: NWF22_20955
DIZ: CT688_05610
TOY: FO059_17465
SCAD: DN051_01765
SALJ: SMD11_0682(hapE)
SPLA: CP981_11500
MIO: AOA12_02825 AOA12_13430 AOA12_19215
MRN: K8F61_04945
MSUW: GCM10025863_18850
LEU: Leucomu_12905
ARZ: AUT26_19680 AUT26_19745
ARX: ARZXY2_4020(hapE)
ARTP: E5206_14925 E5206_18210
AJG: KKR91_13970
AGEG: MUG94_16715
AKO: N9A08_13055
AJR: N2K98_15340
GLU: F0M17_15875 F0M17_15940
GPR: JQN66_16310 JQN66_16375
GNC: QQS42_16535 QQS42_16600
PAEY: KUF55_15805 KUF55_16730
AEZ: C3E78_14050
ACTQ: OG417_12765
NOA: BKM31_13265
FRI: FraEuI1c_2106 FraEuI1c_3128 FraEuI1c_3915
NAKA: H7F38_05510
SACG: FDZ84_29950 FDZ84_37130
AMYY: YIM_36800(hapE6)
AACD: LWP59_17040
PDX: Psed_2079 Psed_2677
PAUT: Pdca_05840
PBRO: HOP40_17195
PPEL: H6H00_16815 H6H00_19165
SSYI: EKG83_16290 EKG83_27315
ACTY: OG774_14300
ABAI: IMCC26256_11166 IMCC26256_111801
BSOL: FSW04_06275 FSW04_06440 FSW04_20620
AYM: YM304_37530
ATQ: GH723_04715
AQZ: KSP35_01975
IAM: HC251_23265
DHI: LH044_14145
TBH: Tbon_00650
TFLA: O0235_13525
AG: AAK54073(hapA)
 » show all
Reference
PMID:11322873
  Authors
Kamerbeek NM, Moonen MJ, Van Der Ven JG, Van Berkel WJ, Fraaije MW, Janssen DB
  Title
4-Hydroxyacetophenone monooxygenase from Pseudomonas fluorescens ACB. A novel flavoprotein catalyzing Baeyer-Villiger oxidation of aromatic compounds.
  Journal
Eur J Biochem 268:2547-57 (2001)
DOI:10.1046/j.1432-1327.2001.02137.x
  Sequence
[ag:AAK54073]
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