KEGG ORTHOLOGY: K14621

ORTHOLOGY: K14621

Entry

K14621                      KO

Symbol

PLB1, PLB

Name

phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]

Pathway

map00564

Glycerophospholipid metabolism

map00565

Ether lipid metabolism

map00590

Arachidonic acid metabolism

map00591

Linoleic acid metabolism

map00592

alpha-Linolenic acid metabolism

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

map04977

Vitamin digestion and absorption

Reaction

R01315

phosphatidylcholine 2-acylhydrolase

R01317

phosphatidylcholine 2-acylhydrolase

R02053

phosphatidylethanolamine 2-acylhydrolase

R02746

1-acyl-sn-glycero-3-phosphocholine acylhydrolase

R02747

2-acyl-sn-glycero-3-phosphocholine acylhydrolase

R03416

1-acyl-sn-glycero-3-phosphoethanolamine aldehydohydrolase

R03417

L-2-lysophosphatidylethanolamine aldehydohydrolase

R07064

phosphatidylcholine 2-acylhydrolase

R07379

plasmenylethanolamine 2-acylhydrolase

R07387

plasmanylcholine 2-acylhydrolase

R07859

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    K14621  PLB1, PLB; phospholipase B1, membrane-associated
   00565 Ether lipid metabolism
    K14621  PLB1, PLB; phospholipase B1, membrane-associated
   00590 Arachidonic acid metabolism
    K14621  PLB1, PLB; phospholipase B1, membrane-associated
   00591 Linoleic acid metabolism
    K14621  PLB1, PLB; phospholipase B1, membrane-associated
   00592 alpha-Linolenic acid metabolism
    K14621  PLB1, PLB; phospholipase B1, membrane-associated
09150 Organismal Systems
  09154 Digestive system
   04977 Vitamin digestion and absorption
    K14621  PLB1, PLB; phospholipase B1, membrane-associated
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K14621  PLB1, PLB; phospholipase B1, membrane-associated
Enzymes [BR:ko01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     K14621  PLB1, PLB; phospholipase B1, membrane-associated
    3.1.1.5  lysophospholipase
     K14621  PLB1, PLB; phospholipase B1, membrane-associated
Membrane trafficking [BR:ko04131]
Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    K14621  PLB1, PLB; phospholipase B1, membrane-associated

Other DBs

GO:	0004623 0004622

Genes

HSA:	151056(PLB1)

PTR:	459117(PLB1)

PPS:	100977414(PLB1)

GGO:	101128893(PLB1)

PON:	100460209(PLB1)

NLE:	100593200(PLB1)

HMH:	116480510(PLB1)

MCC:	100424557(PLB1)

MCF:	102133956(PLB1)

MTHB:

126933846

MNI:	105479730(PLB1)

CSAB:

103220573(PLB1)

CATY:

105578433(PLB1)

PANU:

101019214(PLB1)

TGE:	112604646(PLB1)

MLEU:

105534056(PLB1)

RRO:	104668467 115894175

RBB:	108532745(PLB1)

TFN:	117062533(PLB1)

PTEH:

111546017(PLB1)

CANG:

105521932(PLB1)

CJC:	100400336(PLB1)

SBQ:	101045130(PLB1)

CIMI:

108315954(PLB1)

CSYR:

103250386(PLB1)

MMUR:

105884436(PLB1)

LCAT:

123636752(PLB1)

PCOQ:

105816874(PLB1)

OGA:

100962464

MMU:	665270(Plb1)

MCAL:

110294493(Plb1)

MPAH:

110324523(Plb1)

RNO:	192259(Plb1)

MCOC:

116080018(Plb1)

ANU:	117716957(Plb1)

MUN:	110554523(Plb1)

CGE:	100761810(Plb1)

MAUA:

101828188(Plb1)

PROB:

127220108(Plb1)

PLEU:

114696285(Plb1)

MORG:

121432920(Plb1)

MFOT:

126494311

AAMP:

119807316(Plb1)

NGI:	103730233(Plb1)

HGL:	101699397(Plb1)

CPOC:

100135633(Plb1)

CCAN:

109679883(Plb1)

DORD:

105983582(Plb1)

DSP:	122122449(Plb1)

PLOP:

125356606(Plb1)

NCAR:

124963630

MMMA:

107137030(Plb1)

OCU:	100009309(PLB1)

OPI:	101527047(PLB1)

TUP:	102501362(PLB1)

GVR:	103585442(PLB1)

CFA:	611194(PLB1)

CLUD:

112664596(PLB1)

VVP:	112933015(PLB1)

VLG:	121491875(PLB1)

NPO:	129510912(PLB1)

AML:	100471208(PLB1)

UMR:	103671911(PLB1)

UAH:	113267984(PLB1)

UAR:	123799722(PLB1)

ELK:

111139296

LLV:

125109094

MPUF:

101680268(PLB1)

MNP:	132021243(PLB1)

MLK:	131840594(PLB1)

NVS:	122915198(PLB1)

ORO:	101374070(PLB1)

EJU:	114205893(PLB1)

ZCA:	113938158(PLB1)

MLX:	118007510(PLB1)

NSU:	110587569(PLB1)

LWW:	102729365(PLB1) 115937069

FCA:	101089599(PLB1)

PYU:	121044290(PLB1)

PCOO:

112864112(PLB1)

PBG:	122497308(PLB1)

PVIV:

125162342(PLB1)

LRUF:

124503970

PTG:	102970451(PLB1)

PPAD:

109266508(PLB1)

PUC:

125937797

AJU:

106967918

HHV:	120235903(PLB1)

BTA:	506508(PLB1)

BOM:	102269942(PLB1)

BIU:	109565587(PLB1)

BBUB:

102397314(PLB1)

BBIS:

104989134(PLB1)

CHX:	102171250(PLB1)

OAS:	101113054(PLB1)

BTAX:

128055719(PLB1)

ODA:	120852279(PLB1)

CCAD:

122441912(PLB1)

MBEZ:

129539607(PLB1)

SSC:	100519306(PLB1)

CFR:	102503939(PLB1)

CBAI:

105063809(PLB1)

CDK:	105098563(PLB1)

VPC:	102529523(PLB1)

BACU:

103019186(PLB1)

BMUS:

118905784(PLB1)

LVE:	103088267(PLB1)

OOR:	101277000(PLB1)

DLE:	111174927(PLB1)

PCAD:

114487280(PLB1)

PSIU:

116764307(PLB1)

NASI:

112412772(PLB1)

ECB:	100071076(PLB1)

EPZ:	103549433(PLB1)

EAI:	106837073(PLB1)

MYB:	102255003(PLB1)

MYD:	102751623(PLB1)

MMYO:

118669149(PLB1)

MLF:	102426259(PLB1)

PKL:	118717164(PLB1)

EFUS:

103283141(PLB1)

MNA:	107534832(PLB1)

DRO:	112298034(PLB1)

SHON:

119001471(PLB1)

AJM:	119050449(PLB1)

PDIC:

114499946(PLB1)

PHAS:

123822416(PLB1)

MMF:	118631126(PLB1)

PPAM:

129064559(PLB1)

HAI:	109391027(PLB1)

RFQ:	117033394(PLB1)

PALE:

102883901(PLB1)

PGIG:

120621815(PLB1)

PVP:	105299149(PLB1)

RAY:	107511168(PLB1)

TOD:	119259439(PLB1)

SARA:

101544658 101550276 101550540 101553468

SETR:

126024298(PLB1) 126024306 126024307

LAV:	100653651(PLB1)

TMU:

101361095

ETF:	101654748 101655063

DNM:	101413581(PLB1)

MDO:	768082(PLB1)

GAS:	123233513(PLB1)

SHR:	100930482(PLB1)

AFZ:

127548705

PCW:	110206446(PLB1)

OAA:	100078529(PLB1)

MGP:	100546393(PLB1)

CJO:	107311192(PLB1)

TPAI:

128090154(PLB1)

LMUT:

125689005(PLB1)

NMEL:

110396340(PLB1)

APLA:

101798966(PLB1)

ACYG:

106029775(PLB1)

CATA:

118254025(PLB1)

TGU:	100232535(PLB1)

LSR:	110483075(PLB1)

SCAN:

103821540(PLB1)

PMOA:

120496921(PLB1)

OTC:	121340660(PLB1)

PRUF:

121358683(PLB1)

GFR:	102036623(PLB1)

FAB:	101808718 101812751(PLB1)

OMA:	130251401(PLB1)

PHI:	106628704 106628705(PLB1)

PMAJ:

107202552(PLB1)

CCAE:

111927632(PLB1)

CCW:	104685700(PLB1)

CBRC:

103622755(PLB1)

ETL:	114064850(PLB1)

ZAB:	102074763(PLB1)

SVG:	106853816(PLB1)

MMEA:

130576499(PLB1)

HRT:	120751048(PLB1)

FPG:	101915961(PLB1)

FCH:	102047846(PLB1)

CLV:	102089442(PLB1)

ACUN:

113477931(PLB1)

TALA:

104363295(PLB1)

AFOR:

103902649(PLB1)

ACHC:

115350388(PLB1)

AGEN:

126052689

GCL:

127014628

BREG:

104637251(PLB1)

SHAB:

115613901(PLB1)

ACAR:

114818633(PLB1)

RTD:	128907049(PLB1)

CUCA:

104062232(PLB1)

BRHI:

104498569(PLB1)

AAM:	106485470(PLB1)

AROW:

112962904(PLB1)

NPD:	112953274(PLB1)

DNE:	112995914(PLB1)

SCAM:

104144998(PLB1)

ASN:	102371440(PLB1)

AMJ:	102566737(PLB1)

CPOO:

109319076(PLB1)

GGN:	109304215(PLB1)

PSS:	102463957(PLB1)

CMY:	102943239(PLB1)

CCAY:

125633733(PLB1)

DCC:	119853552(PLB1)

CPIC:

101947653(PLB1)

TST:	117874544(PLB1)

CABI:

116830633(PLB1)

MRV:	120402058(PLB1)

ACS:	100563592 103283043

ASAO:

132761338(PLB1)

PVT:	110078685(PLB1)

SUND:

121914652(PLB1)

PBI:	103051286(PLB1)

PMUR:

107299525

CTIG:

120305347(PLB1)

TSR:	106538236(PLB1)

PGUT:

117671801(PLB1)

APRI:

131187823(PLB1)

PTEX:

113433195(PLB1)

NSS:	113421340(PLB1)

VKO:	123028039(PLB1)

PMUA:

114594577(PLB1)

PRAF:

128411027(PLB1)

ZVI:	118082692 118083254(PLB1)

HCG:	128349645(PLB1)

GJA:	107124490(PLB1)

STOW:

125437430(PLB1)

EMC:	129338746(PLB1)

XLA:	108699833 108716506 108717670

XTR:	100492667 100495859(plb1) 101732808

RTEM:

120935801(PLB1)

BBUF:

120999365(PLB1)

BGAR:

122935553(PLB1)

MUO:	115477656(PLB1)

GSH:	117357292(PLB1) 117364262

DRE:	101886068(si:dkey-177p2.18) 560649(si:ch211-214p16.3)

SRX:	107715939 107721335 107721878

SANH:

107654820 107659236

SGH:	107583542 107583717

CCAR:

109044986 109045081 109078885

CAUA:

113037832 113037921 113062909 113062910 113072504 113075672 113075673 113095747 113117435

CGIB:

127933494 127938651 127976371 127984207(si:dkey-177p2.18)

PTET:

122361523(plb1)

LROH:

127179284(plb1) 127183118(si:dkey-177p2.18)

OMC:	131523202(plb1) 131527230(si:dkey-177p2.18)

PPRM:

120493719(si:dkey-177p2.18) 120494245(plb1)

RKG:	130073461(plb1) 130091842(si:dkey-177p2.18)

MAMB:

125268813(plb1)

CIDE:

127498944

MASI:

127410080 127411554 127416194(si:dkey-177p2.18) 127454956

TROS:

130560522(plb1) 130566184

TDW:	130433950 130436939(plb1)

MANU:

129416955 129430049(si:dkey-177p2.18)

IPU:	108257774 108257913(si:dkey-177p2.18) 108269596(plb1) 108269896

IFU:	128600980 128601282 128601593(si:dkey-177p2.18) 128612933(plb1) 128613194

PHYP:

113525192 113545116 113545259(plb1) 113547666

SMEO:

124377462 124390638(plb1)

TFD:	113641401(plb1) 113643343(si:dkey-177p2.18) 113644521

TVC:	132842262(si:dkey-177p2.18) 132843263 132852228(plb1) 132852710

AMEX:

103028594(plb1) 111191226 111193178 111193190

CMAO:

118815663(si:dkey-177p2.18) 118815844 118823527(plb1) 118824111

EEE:	113570556 113572247(plb1)

CHAR:

116223567(plb1) 116223878 122130951

TRU:	105418815 115252901 115252952

TFS:	130516081(si:dkey-177p2.18) 130516497 130540069(plb1)

TNG:	GSTEN00030412G001 GSTEN00031985G001

LCO:	104932448 104936458 109136708 109143071

NCC:	104958255 104964387(plb1)

TBEN:

117472103(plb1) 117474604 117486911

CGOB:

115027032(plb1) 115027591

PGEO:

117439660 117467279(si:dkey-177p2.18) 117467890(plb1)

GACU:

117548758 117553146(plb1) 117558855(si:dkey-177p2.18)

EMAC:

134876965 134877092(si:dkey-177p2.18) 134881065(plb1)

ELY:	117267592(plb1) 117270442

EFO:	125897513 125897553 125900561(plb1) 125901056(si:dkey-177p2.18)

PLEP:

121953560 121953970 121955855

SLUC:

116057332(plb1) 116066379 116066380

ECRA:

117935352(plb1) 117961429

ESP:	116669648 116679816 116705907 116706685

PFLV:

114546619(plb1) 114572854

GAT:	120807779 120832966(plb1)

PPUG:

119194690 119228077

AFB:	129103966(plb1) 129107591

CLUM:

117727743 117727882(si:dkey-177p2.18) 117751446(plb1) 117751649

PSWI:

130201444 130202261(si:dkey-177p2.18) 130203022

MSAM:

119908530 119910973(plb1) 119910996

SCHU:

122862025 122862043(plb1) 122863253 122863713

CUD:	121521159 121526345(plb1)

ALAT:

119004800 119005157(plb1) 119012366

MZE:	101470994 101477600

ONL:	100692607 102081001 102081816

OAU:	116312715 120433196(si:dkey-177p2.18) 120434837(plb1)

OLA:	101164444(plb1) 105357244

OML:	112147510(plb1) 112157688(si:dkey-177p2.18)

CSAI:

133462545 133464791 133464862(si:dkey-177p2.18)

XMA:	102223452(plb1) 102225455 111611425

XCO:	114158248 114158411

XHE:	116708506 116733719 116733821

PRET:

103457367 103457942 103458749

PFOR:

103135184 103154957(plb1)

PLAI:

106962810 106964673(plb1)

PMEI:

106906585(plb1) 106911127

GAF:	122825857 122846558(plb1)

PPRL:

129365595(plb1) 129368952(si:dkey-177p2.18) 129375218

CVG:	107080756 107088471 107096908

CTUL:

119771571 119775064(plb1)

GMU:	124855619(plb1) 124881653

NFU:	107377838 107392160(plb1)

KMR:	108233136(plb1) 108233399

ALIM:

106518443 106525691

NWH:	119427666(plb1)

AOCE:

111573275 111578341

MCEP:

124999095 124999530 125023146(plb1) 125023391

CSEM:

103381218(plb1)

POV:	109632440 109635983 109636333(plb1) 109642035

SSEN:

122760205 122782443(plb1)

HHIP:

117755514 117756495 117758817

HSP:	118099854 118116510(si:dkey-177p2.18) 118116680(plb1)

SMAU:

118285785 118286470(plb1) 118290136 118290236(si:dkey-177p2.18)

LCF:	108873475 108875083 108896854(si:dkey-177p2.18) 108902197

SDU:	111216413 111225492(plb1) 111238803

SLAL:

111651022 111659872 111661530 111672653

XGL:	120788955 120789338 120795094(plb1) 120795254(si:dkey-177p2.18)

HCQ:	109509713 109517215 109520386

SSCV:

125980979 125990433(si:dkey-177p2.18) 125990671

SBIA:

133496578 133496620(si:dkey-177p2.18) 133512919

PEE:	133412425(plb1) 133417378

PTAO:

133468158 133468667(si:dkey-177p2.18) 133487563 133488205(plb1)

BPEC:

110153648(plb1) 110156767

MALB:

109962371 109968042(plb1)

BSPL:

114849925(plb1)

SJO:	128374913(plb1) 128376862

SASA:

106571632 106571734 106608185

STRU:

115162797 115174395 115174567 115183108

OTW:	112217892 112222909 112250504 112251751(si:dkey-177p2.18)

OMY:	110498318 110522516 110529222(si:dkey-177p2.18) 110529800

OGO:	123990933 123991661(si:dkey-177p2.18) 123995346 124019750

ONE:	115107328 115107933(plb1)

OKI:	109866435 109900910 109901390 116374729

OKE:	118387146 118398471 118398522(si:dkey-177p2.18)

SALP:

111954330 111954458 112068685

SNH:	120019480(plb1)

CCLU:

121548588 121552432(si:dkey-177p2.18) 121552732

ELS:	105015879 105024807(plb1)

SFM:	108929197 108940711

PKI:	111838841 111841926 111850674

AANG:

118222237 118228831

PSPA:

121316439(plb1) 121317693 121324324(si:dkey-177p2.18)

ARUT:

117402878(plb1) 117411207

PSEX:

120526727(plb1)

LCM:	102359766(PLB1) 106702515

CMK:	103187376(si:dkey-177p2.18)

CPLA:

122548494(plb1) 122553958(si:dkey-177p2.18)

PMRN:

116953854

LRJ:	133347022(PLB1) 133356238

BFO:	118404819 118422874

CIN:	100178828 100182192

SCLV:

120348557

SPU:	100890912 100892711 100894066 100894143 578635

APLC:

110981397 110981452

SKO:	100379026 102805697 102805811 102805942 102806057

AME:

BIM:

BTER:

CCAL:

OBB:

OLG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

LHU:

PGC:

OBO:

PCF:

VVE:

NVI:

CSOL:

MDL:

TCA:

DPA:

ATD:

NVL:

BMOR:

BMAN:

MSEX:

DPL:	KGM_210216

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

API:

DNX:

AGS:

RMD:

BTAB:

CLEC:

NLU:

PHU:	Phum_PHUM596330

EAF:

111697031

NAI:	NECAME_11387

LGI:	LOTGIDRAFT_111188

PCAN:

GAE:

HRF:

HRJ:

MYI:	110455531 110460882

PMAX:

117344102

LAK:	106150427 106176885

NVE:

EPA:

AMIL:

PDAM:

SPIS:

DGT:	114527633 114540607

AQU:	100633874 105312064

DFA:

DFA_12052

ACAN:

ACA1_280270

» show all

Reference

PMID:9442065

Authors

Takemori H, Zolotaryov FN, Ting L, Urbain T, Komatsubara T, Hatano O, Okamoto M, Tojo H

Title

Identification of functional domains of rat intestinal phospholipase B/lipase. Its cDNA cloning, expression, and tissue distribution.

Journal

J Biol Chem 273:2222-31 (1998)
DOI:10.1074/jbc.273.4.2222

Sequence

[rno:192259]

Reference

PMID:16011460

Authors

Harrison EH

Title

Mechanisms of digestion and absorption of dietary vitamin A.

Journal

Annu Rev Nutr 25:87-103 (2005)
DOI:10.1146/annurev.nutr.25.050304.092614

LinkDB

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