Entry Symbol ATX, chlB1, mdpB
Name 6-methylsalicylic acid synthase [EC:
2.3.1.165 ]
Pathway map01059 Biosynthesis of enediyne antibiotics
map01110 Biosynthesis of secondary metabolites
Module M00829 3,6-Dimethylsalicylyl-CoA biosynthesis, malonyl-CoA => 6-methylsalicylate => 3,6-dimethylsalicylyl-CoA
Reaction R07253 acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl-reducing, thioester-hydrolysing and cyclizing)
Brite KEGG Orthology (KO) [BR:ko00001 ]ko01000 ]ko01008 ] BRITE hierarchy Other DBs Genes » show all Taxonomy UniProt Reference Authors Fujii I, Ono Y, Tada H, Gomi K, Ebizuka Y, Sankawa U
Title Cloning of the polyketide synthase gene atX from Aspergillus terreus and its identification as the 6-methylsalicylic acid synthase gene by heterologous expression.
Journal Sequence Reference Authors Shao L, Qu XD, Jia XY, Zhao QF, Tian ZH, Wang M, Tang GL, Liu W
Title Cloning and characterization of a bacterial iterative type I polyketide synthase gene encoding the 6-methylsalicyclic acid synthase.
Journal Sequence Reference Authors Beck J, Ripka S, Siegner A, Schiltz E, Schweizer E
Title The multifunctional 6-methylsalicylic acid synthase gene of Penicillium patulum. Its gene structure relative to that of other polyketide synthases.
Journal Sequence Reference Authors Van Lanen SG, Oh TJ, Liu W, Wendt-Pienkowski E, Shen B
Title Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis.
Journal Sequence LinkDB All DBs
