KEGG ORTHOLOGY: K15409

ORTHOLOGY: K15409

Entry

K15409                      KO

Symbol

SRPK1

Name

serine/threonine-protein kinase SRPK1 [EC:2.7.11.1]

Pathway

map05168

Herpes simplex virus 1 infection

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    K15409  SRPK1; serine/threonine-protein kinase SRPK1
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K15409  SRPK1; serine/threonine-protein kinase SRPK1
  09182 Protein families: genetic information processing
   03041 Spliceosome
    K15409  SRPK1; serine/threonine-protein kinase SRPK1
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K15409  SRPK1; serine/threonine-protein kinase SRPK1
Protein kinases [BR:ko01001]
Serine/threonine kinases: CMGC group
  SRPK family [OT]
   K15409  SRPK1; serine/threonine-protein kinase SRPK1
Spliceosome [BR:ko03041]
Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    K15409  SRPK1; serine/threonine-protein kinase SRPK1

Genes

HSA:	6732(SRPK1)

PTR:	462640(SRPK1)

PPS:	100984222(SRPK1)

GGO:	101147832(SRPK1)

PON:	100172042(SRPK1)

NLE:	100593994(SRPK1)

HMH:	116459659(SRPK1)

MCC:	719039(SRPK1)

MCF:	102115891(SRPK1)

MTHB:

126952724

MNI:	105474511(SRPK1)

CSAB:

103221598(SRPK1)

CATY:

105592795(SRPK1)

PANU:

101022782(SRPK1)

TGE:	112622982(SRPK1)

MLEU:

105544219(SRPK1)

RRO:	104682865(SRPK1)

RBB:	108528323(SRPK1) 108528697

TFN:	117082325 117087116(SRPK1)

PTEH:

111542968(SRPK1)

CANG:

105514178(SRPK1)

CJC:	100403396(SRPK1)

SBQ:	101043823(SRPK1)

CIMI:

108300008(SRPK1)

CSYR:

103263385(SRPK1)

MMUR:

105861422(SRPK1) 105863194

LCAT:

123632865(SRPK1)

PCOQ:

105812234(SRPK1)

OGA:	100955959(SRPK1)

MMU:	20815(Srpk1)

MCAL:

110312625(Srpk1)

MPAH:

110337869(Srpk1)

RNO:	361811(Srpk1)

MCOC:

116074303(Srpk1)

ANU:	117724377(Srpk1)

MUN:	110546561(Srpk1)

CGE:	100764390(Srpk1)

MAUA:

101824031(Srpk1)

PROB:

127224213(Srpk1)

PLEU:

114706116(Srpk1)

MORG:

121435408(Srpk1)

MFOT:

126500693

AAMP:

119822587(Srpk1)

NGI:	103739662(Srpk1)

HGL:	101717748(Srpk1)

CPOC:

100730101(Srpk1)

CCAN:

109689852(Srpk1)

DORD:

105995747(Srpk1)

DSP:	122111052(Srpk1)

PLOP:

125352656(Srpk1)

NCAR:

124988474

MMMA:

107143837(Srpk1)

OCU:

100338911

OPI:	101524644(SRPK1)

TUP:	102490975(SRPK1)

GVR:	103607470(SRPK1)

CFA:	474887(SRPK1)

CLUD:

112641473(SRPK1)

VVP:	112913929(SRPK1)

VLG:	121493773(SRPK1)

NPO:	129512522(SRPK1)

AML:	100480308(SRPK1)

UMR:	103665452(SRPK1)

UAH:	113243851(SRPK1)

UAR:	123776199(SRPK1)

ELK:

111152251

LLV:

125102243

MPUF:

101683232(SRPK1)

MNP:	132017919(SRPK1)

MLK:	131834192(SRPK1)

NVS:	122910107(SRPK1)

ORO:	101366804(SRPK1)

EJU:	114222167(SRPK1)

ZCA:	113926548(SRPK1)

MLX:	118001599(SRPK1)

NSU:	110575673(SRPK1)

LWW:	102747290(SRPK1)

FCA:	101100890(SRPK1)

PYU:	121029348(SRPK1)

PCOO:

112861965(SRPK1)

PBG:	122490343(SRPK1)

PVIV:

125165483(SRPK1)

LRUF:

124528052

PTG:	102968481(SRPK1)

PPAD:

109271510(SRPK1)

PUC:

125937863

AJU:

106972808

HHV:	120233807(SRPK1)

BTA:	512631(SRPK1)

BOM:	102280761(SRPK1)

BIU:	109577154(SRPK1)

BBUB:

102396844(SRPK1)

BBIS:

104994936(SRPK1)

CHX:	102177762(SRPK1)

OAS:	101119590(SRPK1)

BTAX:

128056391(SRPK1)

ODA:	120870213(SRPK1)

CCAD:

122429491(SRPK1)

MBEZ:

129543179(SRPK1)

SSC:	100155422(SRPK1)

CFR:	102506893(SRPK1)

CBAI:

105064179(SRPK1)

CDK:	105101342(SRPK1)

VPC:	102541795(SRPK1)

BACU:

103009609(SRPK1)

BMUS:

118904349(SRPK1)

LVE:	103077772(SRPK1)

OOR:	101270273(SRPK1)

DLE:	111178940(SRPK1)

PCAD:

102995072(SRPK1)

PSIU:

116762077(SRPK1)

NASI:

112413863(SRPK1)

ECB:	100063400(SRPK1)

EPZ:	103542325(SRPK1)

EAI:	106824560(SRPK1)

MYB:	102249101(SRPK1)

MYD:	102771620(SRPK1)

MMYO:

118659765(SRPK1)

MLF:	102437635(SRPK1)

PKL:	118705030(SRPK1)

EFUS:

103295512(SRPK1)

MNA:	107545606(SRPK1)

DRO:	112302091(SRPK1)

SHON:

118998976(SRPK1)

AJM:	119050034(SRPK1)

PDIC:

114493924(SRPK1)

PHAS:

123821374(SRPK1)

MMF:	118620885(SRPK1)

PPAM:

129067411(SRPK1)

HAI:	109395986(SRPK1)

RFQ:	117019562(SRPK1)

PALE:

102878470(SRPK1)

PGIG:

120597700(SRPK1)

PVP:	105301033(SRPK1)

RAY:	107497889(SRPK1)

MJV:	108386089(SRPK1)

TOD:	119252385(SRPK1)

SARA:

101540074(SRPK1)

SETR:

125996309(SRPK1)

LAV:	100674002(SRPK1)

TMU:

101361103

ETF:	101655576(SRPK1)

DNM:	101424002(SRPK1)

MDO:	100028720(SRPK1)

GAS:	123245407(SRPK1)

SHR:	100924491(SRPK1)

AFZ:

127561204

PCW:	110217224(SRPK1)

OAA:	100086006(SRPK1)

GGA:	421185(SRPK1)

PCOC:

116238774(SRPK1)

MGP:	100546678(SRPK1)

CJO:	107324613(SRPK1)

TPAI:

128090269(SRPK1)

LMUT:

125684004(SRPK1)

NMEL:

110388273(SRPK1)

APLA:

101802633(SRPK1)

ACYG:

106046167(SRPK1)

CATA:

118255375(SRPK1)

AFUL:

116498750(SRPK1)

TGU:	100219206(SRPK1)

LSR:	110473463(SRPK1)

SCAN:

103823283(SRPK1)

PMOA:

120495943(SRPK1)

OTC:	121347999(SRPK1)

PRUF:

121353417(SRPK1)

GFR:	102033916 102041995(SRPK1)

FAB:	101817762(SRPK1)

OMA:	130266473(SRPK1)

PHI:	102099902(SRPK1)

PMAJ:

107214790(SRPK1)

CCAE:

111939664(SRPK1)

CCW:	104692397(SRPK1)

CBRC:

103625346(SRPK1)

ETL:	114065758(SRPK1)

ZAB:	102066739(SRPK1)

ACHL:

103809112(SRPK1)

SVG:	106850927(SRPK1)

MMEA:

130584311(SRPK1)

HRT:	120762907(SRPK1)

FPG:	101921807(SRPK1)

FCH:	102059551(SRPK1)

CLV:	102083936(SRPK1)

EGZ:	104125711(SRPK1)

NNI:	104013233(SRPK1)

PCRI:

104025435(SRPK1)

PLET:

104618890(SRPK1)

EHS:	104505789(SRPK1)

PCAO:

104051103(SRPK1)

ACUN:

113489035(SRPK1)

TALA:

104355868(SRPK1)

PADL:

103925942(SRPK1)

AFOR:

103893652(SRPK1)

ACHC:

115334812(SRPK1)

HALD:

104321890(SRPK1)

HLE:	104842353(SRPK1)

AGEN:

126052450

GCL:

127026153

CCRI:

104157823(SRPK1)

CSTI:

104554750

CMAC:

104486917(SRPK1)

MUI:	104542470(SRPK1)

BREG:

104632619(SRPK1)

FGA:	104082822(SRPK1)

GSTE:

104258532(SRPK1)

LDI:	104351627(SRPK1)

MNB:	103780058(SRPK1)

OHA:	104336311(SRPK1)

NNT:	104411375(SRPK1)

SHAB:

115602378(SRPK1)

DPUB:

104302153(SRPK1)

PGUU:

104470407(SRPK1)

ACAR:

104531879(SRPK1)

CPEA:

104387594(SRPK1)

AVIT:

104273375(SRPK1)

CVF:	104292363(SRPK1)

RTD:	128900242(SRPK1)

CUCA:

104065109(SRPK1)

TEO:	104374383(SRPK1)

BRHI:

104494535(SRPK1)

AAM:	106487666(SRPK1)

AROW:

112961429(SRPK1)

NPD:	112959206(SRPK1)

TGT:	104566754(SRPK1)

DNE:	112990249(SRPK1)

SCAM:

104139397(SRPK1)

ASN:	102375059(SRPK1)

AMJ:	102561082(SRPK1)

CPOO:

109317500(SRPK1)

GGN:	109295118(SRPK1)

PSS:	102455614(SRPK1)

CMY:	102941791(SRPK1)

CCAY:

125625003(SRPK1)

DCC:	119846296(SRPK1)

CPIC:

101933203(SRPK1)

TST:	117875892(SRPK1)

CABI:

116839134(SRPK1)

MRV:	120404307(SRPK1)

ACS:	100567999(srpk1)

ASAO:

132773741(SRPK1)

PVT:	110079768(SRPK1)

SUND:

121928384(SRPK1)

PBI:	103052907(SRPK1)

PMUR:

107292820(SRPK1)

CTIG:

120298975(SRPK1)

TSR:	106539165(SRPK1)

PGUT:

117664012(SRPK1)

APRI:

131196333(SRPK1)

PTEX:

113446986 113447793

NSS:	113418782 113418975

VKO:	123030111(SRPK1)

PMUA:

114599204(SRPK1)

PRAF:

128415981(SRPK1)

ZVI:	118088104(SRPK1)

HCG:	128324263(SRPK1)

GJA:	107110974(SRPK1)

STOW:

125433597(SRPK1)

EMC:	129330526(SRPK1)

XLA:	432197(srpk1.S)

XTR:	550105(srpk1)

NPR:

RTEM:

BBUF:

BGAR:

MUO:	115481471(SRPK1)

GSH:	117347114(SRPK1)

DRE:	323679(srpk1a) 791187(srpk1b)

SRX:	107714507 107731242 107745731 107751004

SANH:

107667998 107678882 107680449 107699336

SGH:	107549962 107555984 107591832 107592563

CCAR:

109066892 109066895 109067165 109092455

CAUA:

113055096 113069392 113076475 113107627

CGIB:

127963764 127968397 128018667 128022593

PTET:

122350170(srpk1a) 122353561(srpk1b)

LROH:

127169797(srpk1a) 127173062(srpk1b)

OMC:	131546264(srpk1a) 131549667(srpk1b)

PPRM:

120469058(srpk1a) 120473449(srpk1b)

RKG:	130071801(srpk1b) 130094632(srpk1a)

MAMB:

125257054(srpk1b) 125279791(srpk1a)

CIDE:

127516998 127522060

MASI:

127414450 127423808 127426316 127428235

TROS:

130568406(srpk1a) 130571728(srpk1b)

TDW:	130410419(srpk1b) 130440262(srpk1a)

MANU:

129415052(srpk1a) 129427483(srpk1b)

IPU:	108254807(srpk1b) 108265181(srpk1a)

IFU:	128607886(srpk1a) 128625231(srpk1b)

PHYP:

113535051(srpk1) 113539645

SMEO:

124399989(srpk1a) 124402264(srpk1b)

TFD:	113656308(srpk1a) 113661911(srpk1b)

TVC:	132837956(srpk1b) 132853432(srpk1a)

AMEX:

103045240 103047501(srpk1)

CMAO:

118799540(srpk1b) 118813188(srpk1a)

EEE:	113585540 113590097(srpk1)

CHAR:

105893673(srpk1a) 105898141(srpk1b) 105904143

TRU:	101070116(srpk1) 101074207

TFS:	130524098(srpk1b) 130529425(srpk1a)

TNG:	GSTEN00013029G001 GSTEN00028161G001

LCO:	104926610(srpk1) 109140883

NCC:	104951421 104964412(srpk1)

TBEN:

117486528(srpk1b) 117494212(srpk1a)

CGOB:

115008351 115010872(srpk1)

PGEO:

117446704(srpk1b) 117449170(srpk1a)

GACU:

117541965(srpk1a) 117547507(srpk1b)

EMAC:

134865313(srpk1a) 134883104(srpk1b)

ELY:	117257216(srpk1b) 117258044(srpk1a)

EFO:	125891376(srpk1a) 125897462(srpk1b)

PLEP:

121946699(srpk1a) 121953836(srpk1b)

SLUC:

116040795(srpk1a) 116067413(srpk1b)

ECRA:

117943737(srpk1b) 117947166(srpk1a)

ESP:	116687279 116692204

PFLV:

114554400 114558490(srpk1)

GAT:	120828909(srpk1a) 120835276(srpk1b)

PPUG:

119221848(srpk1a) 119229905(srpk1b)

AFB:	129099802(srpk1a) 129105380(srpk1b)

CLUM:

117731083(srpk1b) 117734020(srpk1a)

PSWI:

130200203(srpk1a) 130208498(srpk1b)

MSAM:

119885955(srpk1b) 119905574(srpk1a)

SCHU:

122868210(srpk1b) 122883527(srpk1a)

CUD:	121507042(srpk1b) 121517259(srpk1a)

ALAT:

119021964(srpk1b) 119023049(srpk1a)

MZE:	101475369(srpk1) 101476691

ONL:	100692146 100701465(srpk1)

OAU:	116309702(srpk1a) 116326447(srpk1b)

OLA:	101167038(srpk1) 101171240

OML:	112139316(srpk1b) 112158854(srpk1a)

CSAI:

133448811(srpk1b) 133457239(srpk1a)

XMA:	102217850(srpk1) 102231493

XCO:	114135070 114144607(srpk1)

XHE:	116710480 116726525(srpk1)

PRET:

103464909 103467286(srpk1)

PFOR:

103129670 103141201 103144354

PLAI:

106955116 106960469(srpk1)

PMEI:

106917394 106931366

GAF:	122834748(srpk1b) 122837265(srpk1a)

PPRL:

129353386(srpk1b) 129372412(srpk1a)

CVG:	107087489 107101433

CTUL:

119782205(srpk1a) 119791784(srpk1b)

GMU:	124857112(srpk1b) 124870221(srpk1a)

NFU:	107385561 107390817(srpk1)

KMR:	108244592(srpk1a) 108246872(srpk1b)

ALIM:

106513329 106525489(srpk1)

NWH:	119411664(srpk1b) 119417638(srpk1a)

AOCE:

111566983(srpk1) 111577615 111587879

MCEP:

125006778(srpk1b) 125013883(srpk1a)

CSEM:

103384603(srpk1) 103386139

POV:	109629234 109630894(srpk1)

SSEN:

122767559(srpk1b) 122777088(srpk1a)

HHIP:

117761575(srpk1b) 117764157(srpk1a)

HSP:	118104879(srpk1b) 118110969(srpk1a)

SMAU:

118309545(srpk1b) 118317255(srpk1a)

LCF:	108876518(srpk1a) 108884070(srpk1b)

SDU:	111219189(srpk1) 111221705

SLAL:

111667673 111670685(srpk1)

XGL:	120803884(srpk1a) 120807553(srpk1b)

HCQ:	109510486 109522221

SSCV:

125977867 125987818

SBIA:

133507579(srpk1b) 133511425(srpk1a)

PEE:	133407117(srpk1a) 133408659(srpk1b)

PTAO:

133483086(srpk1b) 133485162(srpk1a)

BPEC:

110164671 110165789

MALB:

109956158 109971082(srpk1)

BSPL:

114855787(srpk1b) 114859150(srpk1a)

SJO:	128356298(srpk1b) 128357952(srpk1a)

SASA:

106566080 106566414 106572836 106582688

STRU:

115151050 115165353 115168662 115207366

OTW:	112215248 112222400 112254162(srpk1b) 112263150

OMY:	110492651 110494755 110527716 110532780

OGO:	124002943 124019004 124031630 124045495

ONE:	115101943 115135535

OKI:	109869227 109878956 109890809 109907091

OKE:	118360451 118373201 118378669 118399923

SALP:

111969699 111976815 112069857 112070890

SNH:	120040731 120058327 120061503 120065008

CCLU:

121537701 121546110 121574765(srpk1b) 121578332

ELS:	105023763 105027118

SFM:	108931253 108938258

PKI:	111835998 111856189

AANG:

118208127 118211714(srpk1b)

LOC:	102696756(srpk1)

PSPA:

121299773 121304703

ARUT:

117397269

PSEX:

120526228(srpk1b)

LCM:	102361962(SRPK1)

CPLA:

HOC:

LERI:

PMRN:

LRJ:

DME:	Dmel_CG8174(SRPK)

DER:

6548344

DSE:

6609279

DSI:	Dsimw501_GD11112(Dsim_GD11112)

DYA:	Dyak_GE11700

DSR:

110177822

DPO:

4804852

DPE:	6597763 6602137

DMN:	108159405 117188173

DWI:	6652471 6652966

DGR:

6560413

DMO:	Dmoj_GI16453 Dmoj_GI19404

DAZ:	108615424 108618035

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ009957

CPII:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_213593

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:	110380330(srpK)

HZE:

TNL:

SLIU:

OFU:

PXY:

PGW:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:	103505999 103512158

CLEC:

HHAL:

NLU:

HVI:

MQU:	129002060 129002121

PHU:	Phum_PHUM521080

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

PVM:

HAME:

PTRU:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

CSCU:

PTEP:

ABRU:

UDV:

LPOL:

CEL:	CELE_B0464.5(spk-1)

CBR:	CBG_10087(Cbr-spk-1)

CRQ:	GCK72_009428

LOA:	LOAG_03178

TSP:

Tsp_08274

HRO:	HELRODRAFT_190406

PVUL:

GAE:

HRJ:

CRG:

CVN:

MCAF:

MMER:

RPHI:

DPOL:

NVE:

EPA:

ATEN:

AMIL:

PDAM:

SPIS:

HSY:

TDC:

CME:	CYME_CMK182C

CCI:	CC1G_10260

MRR:

Moror_268

TET:	TTHERM_00069440 TTHERM_00217180

PTM:	GSPATT00036130001

» show all

Reference

PMID:10390541

Authors

Papoutsopoulou S, Nikolakaki E, Chalepakis G, Kruft V, Chevaillier P, Giannakouros T

Title

SR protein-specific kinase 1 is highly expressed in testis and phosphorylates protamine 1.

Journal

Nucleic Acids Res 27:2972-80 (1999)
DOI:10.1093/nar/27.14.2972

Sequence

[hsa:6732] [mmu:20815]

Reference

PMID:8208298

Authors

Gui JF, Lane WS, Fu XD

Title

A serine kinase regulates intracellular localization of splicing factors in the cell cycle.

Journal

Nature 369:678-82 (1994)
DOI:10.1038/369678a0

Sequence

[hsa:6732]

LinkDB

DBGET integrated database retrieval system