KEGG   ORTHOLOGY: K16384
Entry
K16384                      KO                                     
Symbol
amphC, nysC
Name
polyene macrolide polyketide synthase
Pathway
map01052  Type I polyketide structures
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K16384  amphC, nysC; polyene macrolide polyketide synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K16384  amphC, nysC; polyene macrolide polyketide synthase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide synthase (PKS)
  Modular type I PKS
   cis-AT PKS
    Polyene macrolide PKS
     K16384  amphC, nysC; polyene macrolide polyketide synthase
Genes
MSPG: F6B93_19325
NSPU: IFM12276_36020
SGRF: SGFS_005530
SSOI: I1A49_17540
STRE: GZL_00790
SNR: SNOUR_03760
SALU: DC74_7926
SNF: JYK04_07270(pikAII_2)
SPLA: CP981_04550
SGJ: IAG43_33735
SDUR: M4V62_43260
SCIR: STRCI_001089
SXT: KPP03845_106194(pikAII_4)
SGK: PET44_03385
SANT: QR300_27835
SYUN: MOV08_03260
SOV: QZH56_02575 QZH56_07140
AROO: NQK81_07605
KBU: Q4V64_44535
SCOR: J3U87_08740
AG: AAF71776(nysC) AAK73514(amphC)
 » show all
Reference
PMID:11451671 (amphC)
  Authors
Caffrey P, Lynch S, Flood E, Finnan S, Oliynyk M
  Title
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.
  Journal
Chem Biol 8:713-23 (2001)
DOI:10.1016/S1074-5521(01)00046-1
  Sequence
[ag:AAK73514]
Reference
PMID:10873841 (nysC)
  Authors
Brautaset T, Sekurova ON, Sletta H, Ellingsen TE, StrLm AR, Valla S, Zotchev SB
  Title
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.
  Journal
Chem Biol 7:395-403 (2000)
DOI:10.1016/S1074-5521(00)00120-4
  Sequence
[ag:AAF71776]
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