KEGG ORTHOLOGY: K16686

ORTHOLOGY: K16686

Entry

K16686                      KO

Symbol

SAV1, Sav

Name

scaffold protein salvador

Pathway

map04214

Apoptosis - fly

map04390

Hippo signaling pathway

map04391

Hippo signaling pathway - fly

map04392

Hippo signaling pathway - multiple species

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    K16686  SAV1, Sav; scaffold protein salvador
   04391 Hippo signaling pathway - fly
    K16686  SAV1, Sav; scaffold protein salvador
   04392 Hippo signaling pathway - multiple species
    K16686  SAV1, Sav; scaffold protein salvador
09140 Cellular Processes
  09143 Cell growth and death
   04214 Apoptosis - fly
    K16686  SAV1, Sav; scaffold protein salvador

Genes

HSA:	60485(SAV1)

PTR:	452899(SAV1) 738861(GYPE2)

PPS:	100977676(SAV1) 117974336

GGO:	101140719(SAV1)

PON:	100435936(SAV1)

NLE:	100603888(SAV1)

HMH:	116484467(SAV1)

MCC:	706424(SAV1)

MCF:	101925164(SAV1)

MTHB:

126958522

MNI:	105481837(SAV1)

CSAB:

103228963(SAV1)

CATY:

105586604(SAV1)

PANU:

101006986(SAV1)

TGE:	112628293(SAV1)

MLEU:

105553621(SAV1)

RRO:	104682745(SAV1)

RBB:	108513649(SAV1)

TFN:	117069664(SAV1)

PTEH:

111549433(SAV1)

CANG:

105522387(SAV1)

CJC:	100415144(SAV1)

SBQ:	101046327(SAV1)

CIMI:

108287989(SAV1)

CSYR:

103276414(SAV1)

MMUR:

105867638(SAV1)

LCAT:

123649388(SAV1)

PCOQ:

105825913(SAV1)

OGA:	100940724(SAV1)

MMU:	64010(Sav1)

MCAL:

110306679(Sav1)

MPAH:

110324307(Sav1)

RNO:	299116(Sav1)

MCOC:

116079830(Sav1)

ANU:	117716900(Sav1)

MUN:	110558843(Sav1)

CGE:	100766170(Sav1)

MAUA:

101838854(Sav1)

PROB:

127230655(Sav1)

PLEU:

114684143(Sav1)

MORG:

121452387(Sav1)

MFOT:

126508344

AAMP:

119819101(Sav1)

NGI:	103731507(Sav1)

HGL:	101726669(Sav1)

CPOC:

100728249(Sav1)

CCAN:

109687220(Sav1)

DORD:

105982680(Sav1)

DSP:	122106491(Sav1)

PLOP:

125363425(Sav1)

NCAR:

124976184

MMMA:

107146708(Sav1)

OCU:

100350937

OPI:	101526725(SAV1)

TUP:	102482180(SAV1)

GVR:	103582510 103589428(SAV1)

CFA:	480319(SAV1)

CLUD:

112657035(SAV1)

VVP:	112921446(SAV1)

VLG:	121492966(SAV1)

NPO:	129496260(SAV1)

AML:	100471944(SAV1)

UMR:	103665306(SAV1)

UAH:	113266215(SAV1)

UAR:	123793249(SAV1)

ELK:

111161298

LLV:

125103696

MPUF:

101679498(SAV1)

MNP:	131999933(SAV1)

MLK:	131836544(SAV1)

NVS:	122893056(SAV1)

ORO:	101362553(SAV1)

EJU:	114207503(SAV1)

ZCA:	113910321(SAV1)

MLX:	118002158(SAV1)

NSU:	110590525(SAV1)

LWW:	102737859(SAV1)

FCA:	101096154(SAV1)

PYU:	121031749(SAV1)

PCOO:

112855762(SAV1)

PBG:	122469075(SAV1)

PVIV:

125167518(SAV1)

LRUF:

124512203

PTG:	102962029(SAV1)

PPAD:

109268498(SAV1)

PUC:

125909515

AJU:

106981944

HHV:	120220275(SAV1)

BTA:	516557(SAV1)

BOM:	102268056(SAV1)

BIU:	109565023(SAV1)

BBUB:

102414280(SAV1)

BBIS:

104990278(SAV1)

CHX:	102185923(SAV1)

OAS:	101104666(SAV1)

BTAX:

128054436(SAV1)

ODA:	120853119(SAV1)

CCAD:

122443471(SAV1)

MBEZ:

129563209(SAV1)

SSC:	100156165(SAV1)

CFR:	102515400(SAV1)

CBAI:

105078431(SAV1)

CDK:	105091411(SAV1)

VPC:	102539630(SAV1)

BACU:

102998764(SAV1)

BMUS:

118889696(SAV1)

LVE:	103072979(SAV1)

OOR:	101287217(SAV1)

DLE:	111173172(SAV1)

PCAD:

102981231(SAV1)

PSIU:

116748403(SAV1)

NASI:

112392193(SAV1)

ECB:	100066557(SAV1)

EPZ:	103559181(SAV1)

EAI:	106839502(SAV1)

MYB:	102263616(SAV1)

MYD:	102766579(SAV1)

MMYO:

118655050(SAV1)

MLF:	102434744(SAV1)

PKL:	118718404(SAV1)

EFUS:

103283754(SAV1)

MNA:	107525860(SAV1)

DRO:	112311358(SAV1)

SHON:

118992382(SAV1)

AJM:	119057051(SAV1)

PDIC:

114492586(SAV1)

PHAS:

123808195(SAV1)

MMF:	118632634(SAV1)

PPAM:

129066044(SAV1)

HAI:	109375232(SAV1)

RFQ:	117023936(SAV1)

PALE:

102888026(SAV1)

PGIG:

120604447(SAV1)

PVP:	105310250(SAV1)

RAY:	107511444(SAV1)

MJV:	108402320(SAV1)

TOD:	119239078(SAV1)

SARA:

101557212(SAV1)

SETR:

125999342(SAV1)

LAV:	100674511(SAV1)

TMU:

101349256

ETF:	101648114(SAV1)

DNM:	101422072(SAV1)

MDO:	100010219(SAV1)

GAS:	123237676(SAV1)

SHR:	100913559(SAV1)

AFZ:

127549750

PCW:	110220598(SAV1)

OAA:	100084738(SAV1)

GGA:	423578(SAV1)

PCOC:

116234592(SAV1)

MGP:	100541762(SAV1)

CJO:	107315504(SAV1)

TPAI:

128087224(SAV1)

LMUT:

125695099(SAV1)

NMEL:

110401963(SAV1)

APLA:

101803691(SAV1)

ACYG:

106049311(SAV1)

CATA:

118250223(SAV1)

AFUL:

116489654(SAV1)

TGU:	100228633(SAV1)

LSR:	110474779(SAV1)

SCAN:

103826308(SAV1)

PMOA:

120497055(SAV1)

OTC:	121338697(SAV1)

PRUF:

121348677(SAV1)

GFR:	102031872(SAV1)

FAB:	101819168(SAV1)

OMA:	130253493(SAV1)

PHI:	102113270(SAV1)

PMAJ:

107205882(SAV1)

CCAE:

111929643(SAV1)

CCW:	104695894(SAV1)

CBRC:

103618856(SAV1)

ETL:	114070144(SAV1)

ACHL:

103800813(SAV1)

SVG:	106858948(SAV1)

MMEA:

130584189(SAV1)

HRT:	120753616(SAV1)

FPG:	101912368(SAV1)

FCH:	102057287(SAV1)

CLV:	102088007(SAV1)

EGZ:	104135023(SAV1)

NNI:	104019451(SAV1)

PCRI:

104024833(SAV1)

PLET:

104614391(SAV1)

EHS:	104513516(SAV1)

PCAO:

104047002(SAV1)

ACUN:

113480816(SAV1)

TALA:

104362872(SAV1)

PADL:

103915991(SAV1)

AFOR:

103907639(SAV1)

ACHC:

115350435(SAV1)

HALD:

104311994(SAV1)

HLE:	104839467(SAV1)

AGEN:

126050735

GCL:

127017324

CCRI:

104160397(SAV1)

CSTI:

104553935(SAV1)

CMAC:

104477011(SAV1)

MUI:	104537448(SAV1)

BREG:

104643852(SAV1)

FGA:	104074310(SAV1)

GSTE:

104257078(SAV1)

LDI:	104346682(SAV1)

MNB:	103771528(SAV1)

OHA:	104327775(SAV1)

NNT:	104411697(SAV1)

SHAB:

115607507(SAV1)

DPUB:

104299350(SAV1)

PGUU:

104467792(SAV1)

ACAR:

104531252(SAV1)

CPEA:

104394476(SAV1)

AVIT:

104271069(SAV1)

CVF:	104294300(SAV1)

RTD:	128908239(SAV1)

CUCA:

104057416(SAV1)

TEO:	104370191(SAV1)

BRHI:

104499422(SAV1)

AAM:	106491617(SAV1)

AROW:

112961225(SAV1)

NPD:	112957792(SAV1)

TGT:	104576530(SAV1)

DNE:	112993931(SAV1)

SCAM:

104145365(SAV1)

ASN:	102387931(SAV1)

AMJ:	102567340(SAV1)

CPOO:

109320709(SAV1)

GGN:	109298324(SAV1)

PSS:	102456522(SAV1)

CMY:	102947771(SAV1)

CCAY:

125637737(SAV1)

DCC:	119857920(SAV1)

CPIC:

101931382(SAV1)

TST:	117876643(SAV1)

CABI:

116822060(SAV1)

MRV:	120405442(SAV1)

ACS:

100557264

ASAO:

132760754(SAV1)

PVT:	110089149(SAV1)

SUND:

121919447(SAV1)

PBI:	103065265(SAV1)

PMUR:

107293427(SAV1)

CTIG:

120301827(SAV1)

TSR:	106546793(SAV1)

PGUT:

117675053(SAV1)

APRI:

131188102(SAV1)

PTEX:

113435142(SAV1)

NSS:	113414127(SAV1)

VKO:	123026750(SAV1)

PMUA:

114592822(SAV1)

PRAF:

128413635(SAV1)

ZVI:	118075954(SAV1)

HCG:	128339906(SAV1)

GJA:	107122510(SAV1)

STOW:

125427111

EMC:	129324550(SAV1)

XLA:	108699791(sav1.S) 447543(sav1.L)

XTR:	448321(sav1)

NPR:	108788590(SAV1)

RTEM:

120920230(SAV1)

BBUF:

120982568(SAV1)

BGAR:

122921479(SAV1)

MUO:	115477265(SAV1)

GSH:	117363730(SAV1)

DRE:	447821(sav1)

SRX:	107705447 107736858

SANH:

107654943 107682971

SGH:	107553191 107602930 107602931

CCAR:

109059128 109059146(sav1)

CAUA:

113056801(sav1)

CGIB:

127970525 128026011

PTET:

122356987(sav1)

LROH:

127175554(sav1)

OMC:	131552782(sav1)

PPRM:

120467864(sav1)

RKG:	130088243(sav1)

MAMB:

125277311(sav1)

CIDE:

127525064

MASI:

127411657 127414217

TROS:

130559231(sav1)

TDW:	130431305(sav1)

MANU:

129416228(sav1)

IPU:

108263513

IFU:	128605844(sav1)

PHYP:

113537880(sav1)

SMEO:

124400558(sav1)

TFD:	113661035(sav1)

TVC:	132847442(sav1)

AMEX:

103025171(sav1)

CMAO:

118810662(sav1)

EEE:	113583457(sav1)

CHAR:

105891001(sav1)

TRU:	101080105(sav1)

TFS:	130539902(sav1)

TNG:	GSTEN00035784G001

LCO:	104937954(sav1)

NCC:	104954139(sav1)

TBEN:

117481371(sav1)

PGEO:

117467291(sav1)

GACU:

117558003(sav1)

EMAC:

134881017(sav1)

ELY:	117267657(sav1)

EFO:	125901243(sav1)

PLEP:

121953944(sav1)

SLUC:

116057423(sav1)

ECRA:

117935422(sav1)

ESP:	116669720(sav1)

PFLV:

114546506(sav1)

GAT:	120833356(sav1)

PPUG:

119227442(sav1)

AFB:	129103176(sav1)

CLUM:

117725286(sav1)

PSWI:

130201083(sav1)

MSAM:

119910241(sav1)

SCHU:

122861411(sav1)

CUD:	121526301(sav1)

ALAT:

119004558(sav1)

MZE:	101473946(sav1)

ONL:	100702084(sav1)

OAU:	116318085(sav1)

OLA:	101159545(sav1)

OML:	112148441(sav1)

CSAI:

133462083(sav1)

XMA:	102234511(sav1)

XCO:	114134414(sav1)

XHE:	116709295(sav1)

PRET:

103458318(sav1)

PFOR:

103144727(sav1)

PLAI:

106946978(sav1)

PMEI:

106922071(sav1)

GAF:	122845945(sav1)

PPRL:

129365085(sav1)

CVG:	107097182(sav1)

CTUL:

119783571(sav1)

GMU:	124855371(sav1)

NFU:	107391753(sav1)

KMR:	108237562(sav1)

ALIM:

106511144(sav1) 106517965

NWH:	119427057(sav1)

AOCE:

111584585(sav1)

MCEP:

125023565(sav1)

CSEM:

103380859(sav1)

POV:	109636313(sav1)

SSEN:

122782869(sav1)

HHIP:

117756673(sav1)

HSP:	118116566(sav1)

SMAU:

118285750(sav1)

LCF:

108886703

SDU:	111225491(sav1)

SLAL:

111665868(sav1)

XGL:	120795684(sav1)

HCQ:	109517408(sav1)

SSCV:

125981039

SBIA:

133513099(sav1)

PEE:	133412773(sav1)

PTAO:

133488348(sav1)

BPEC:

110167122(sav1)

MALB:

109973396(sav1)

BSPL:

114848670(sav1)

SJO:	128375055(sav1)

SASA:

106601755(sav1) 106611457

STRU:

115161903 115172976(sav1)

OTW:	112247872 112262358(sav1)

OMY:	110498279(sav1) 110505959

OGO:	124001328(sav1) 124046781

ONE:	115115181 115146492(sav1)

OKI:	109881837(sav1) 109904627

OKE:	118362011(sav1) 118373684

SALP:

112069981 112072061

SNH:	120023781 120060123(sav1)

CCLU:

121539102(sav1) 121544580

ELS:	114828668 114840934

SFM:	108919459(sav1)

PKI:	111842709(sav1)

AANG:

118221424(sav1)

LOC:	102682168(sav1)

PSPA:

121324159(sav1) 121329826

ARUT:

117415748 117421978

PSEX:

120518340(sav1)

LCM:	102366607(SAV1)

CMK:	103175267(sav1)

RTP:	109914932(sav1)

CPLA:

122553589(sav1)

HOC:	132817918(sav1)

LERI:

129700528(sav1)

PMRN:

116939706 116953995(SAV1)

LRJ:	133347358 133356302(SAV1)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

SKO:

DME:	Dmel_CG33193(sav)

DER:

6554754

DSI:	Dsimw501_GD18409(Dsim_GD18409)

DYA:	Dyak_GE23988

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI10759

DAZ:

DNV:

DHE:

CCAT:

BOD:

RZE:

AOQ:

TDA:	119665367 119685369 119685370

MDE:

101893152

SCAC:

106082437

LCQ:

111681613

LSQ:	119613942 119614943

GFS:

ECOE:

CLON:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AAG:

AALB:

CQU:	CpipJ_CPIJ006349

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

AROA:

TCA:

DPA:

SOY:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_202281

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

PGW:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM105930

FOC:

TPAL:

ZNE:

CSEC:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_16039

DMK:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

CEL:	CELE_T10H10.3(sav-1)

CBR:	CBG_02143(Cbr-sav-1)

CRQ:	GCK72_023932

BMY:	BM_BM5724(Bma-sav-1)

LOA:	LOAG_06931

TSP:

Tsp_07055

LGI:	LOTGIDRAFT_189497

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CANU:

MYI:

PMAX:

MMER:

OBI:

OSN:

LAK:	106176293 106178708

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

MBR:	MONBRDRAFT_23221

SRE:	PTSG_01509

» show all

Reference

PMID:11027580

Authors

Valverde P

Title

Cloning, expression, and mapping of hWW45, a novel human WW domain-containing gene.

Journal

Biochem Biophys Res Commun 276:990-8 (2000)
DOI:10.1006/bbrc.2000.3582

Sequence

[hsa:60485]

Reference

PMID:21104395

Authors

Park Y, Park J, Lee Y, Lim W, Oh BC, Shin C, Kim W, Lee Y

Title

Mammalian MST2 kinase and human Salvador activate and reduce estrogen receptor alpha in the absence of ligand.

Journal

J Mol Med (Berl) 89:181-91 (2011)
DOI:10.1007/s00109-010-0698-y

Sequence

[hsa:60485]

LinkDB

DBGET integrated database retrieval system