KEGG   ORTHOLOGY: K17457
Entry
K17457                      KO                                     
Symbol
PPP1R12C, MBS85
Name
protein phosphatase 1 regulatory subunit 12C
Pathway
map04270  Vascular smooth muscle contraction
map04510  Focal adhesion
map04810  Regulation of actin cytoskeleton
map04921  Oxytocin signaling pathway
map05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
 09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
Genes
HSA: 54776(PPP1R12C)
PTR: 456295(PPP1R12C)
PPS: 100967966(PPP1R12C)
GGO: 101136268(PPP1R12C) 115933218
PON: 100444334(PPP1R12C)
NLE: 100596166(PPP1R12C)
HMH: 116479601(PPP1R12C)
MCC: 114674157(PPP1R12C) 698538
MCF: 102119955(PPP1R12C)
MTHB: 126943194
MNI: 105496974(PPP1R12C)
CSAB: 103235290(PPP1R12C)
CATY: 105582740(PPP1R12C)
PANU: 101014051(PPP1R12C)
TGE: 112613329(PPP1R12C)
MLEU: 105551618(PPP1R12C)
RRO: 104674755(PPP1R12C)
RBB: 108542522(PPP1R12C)
TFN: 117091723(PPP1R12C)
PTEH: 111521200(PPP1R12C)
CANG: 105504872(PPP1R12C)
CJC: 100407435(PPP1R12C)
SBQ: 101046107(PPP1R12C)
CIMI: 108316604(PPP1R12C)
CSYR: 103267507(PPP1R12C)
MMUR: 105877190(PPP1R12C)
LCAT: 123624687(PPP1R12C)
PCOQ: 105809239(PPP1R12C)
OGA: 100963170(PPP1R12C)
MMU: 232807(Ppp1r12c)
MCAL: 110297840(Ppp1r12c)
MPAH: 110336360(Ppp1r12c)
RNO: 499076(Ppp1r12c)
MCOC: 116101543(Ppp1r12c)
ANU: 117701032(Ppp1r12c)
MUN: 110561072(Ppp1r12c)
CGE: 100765970(Ppp1r12c)
MAUA: 101831438(Ppp1r12c)
PROB: 127238860(Ppp1r12c)
PLEU: 114689078(Ppp1r12c)
MORG: 121450029(Ppp1r12c)
MFOT: 126493652
AAMP: 119821031(Ppp1r12c)
NGI: 103744825(Ppp1r12c)
HGL: 101714373(Ppp1r12c)
CPOC: 100714649(Ppp1r12c)
CCAN: 109696269(Ppp1r12c)
DORD: 105999544(Ppp1r12c)
DSP: 122110725(Ppp1r12c)
PLOP: 125339077(Ppp1r12c)
NCAR: 124966901
MMMA: 107158861(Ppp1r12c)
OPI: 101533680(PPP1R12C)
TUP: 102475906(PPP1R12C)
GVR: 103594694(PPP1R12C)
CFA: 100683226(PPP1R12C)
CLUD: 112645002(PPP1R12C)
VVP: 112909382(PPP1R12C)
VLG: 121485042(PPP1R12C)
NPO: 129500660(PPP1R12C)
AML: 100476917(PPP1R12C)
UMR: 103680310(PPP1R12C)
UAH: 113247365(PPP1R12C)
UAR: 123786950(PPP1R12C)
ELK: 111140038
LLV: 125089161
MPUF: 101691499(PPP1R12C)
MNP: 132005432(PPP1R12C)
MLK: 131818802(PPP1R12C)
NVS: 122912186(PPP1R12C)
ORO: 101384064(PPP1R12C)
EJU: 114202068(PPP1R12C)
ZCA: 113935792(PPP1R12C)
MLX: 117997778(PPP1R12C)
LWW: 102729203(PPP1R12C)
FCA: 101092809(PPP1R12C)
PYU: 121023384(PPP1R12C)
PBG: 122493745(PPP1R12C)
PVIV: 125152784(PPP1R12C)
LRUF: 124527723
PTG: 102964615(PPP1R12C)
PPAD: 109259902(PPP1R12C)
PUC: 125916103
AJU: 106980875
HHV: 120239719(PPP1R12C)
BTA: 512431(PPP1R12C)
BOM: 102273254(PPP1R12C)
BIU: 109571856(PPP1R12C)
BBUB: 102403593(PPP1R12C)
BBIS: 104984178(PPP1R12C)
CHX: 102187707(PPP1R12C)
OAS: 101122546(PPP1R12C)
BTAX: 128063185(PPP1R12C)
ODA: 120873035(PPP1R12C)
CCAD: 122420802(PPP1R12C)
MBEZ: 129545961(PPP1R12C)
SSC: 100626700(PPP1R12C)
CFR: 102511905(PPP1R12C)
CBAI: 105074352(PPP1R12C)
CDK: 105098775(PPP1R12C)
VPC: 102533230(PPP1R12C)
BACU: 103010788(PPP1R12C)
BMUS: 118885242(PPP1R12C)
LVE: 103085204(PPP1R12C)
OOR: 101277066(PPP1R12C)
DLE: 111180975(PPP1R12C)
PCAD: 102987074(PPP1R12C)
PSIU: 116743754(PPP1R12C)
NASI: 112406444(PPP1R12C)
EPZ: 103562875(PPP1R12C)
EAI: 106840918(PPP1R12C)
MYB: 102245599(PPP1R12C)
MYD: 102759047(PPP1R12C) 102760558
MMYO: 118655200(PPP1R12C)
MLF: 102421040(PPP1R12C)
PKL: 118715912(PPP1R12C)
EFUS: 103303380(PPP1R12C)
MNA: 107541310(PPP1R12C)
DRO: 112314020(PPP1R12C)
SHON: 118981343(PPP1R12C)
AJM: 119059962(PPP1R12C)
PDIC: 114511524(PPP1R12C)
PHAS: 123813340(PPP1R12C)
MMF: 118639397(PPP1R12C)
PPAM: 129082609(PPP1R12C)
HAI: 109373751(PPP1R12C)
RFQ: 117034835(PPP1R12C)
PALE: 102878573(PPP1R12C)
PGIG: 120598380(PPP1R12C)
PVP: 105304953(PPP1R12C)
RAY: 107515441(PPP1R12C)
MJV: 108396329(PPP1R12C)
TOD: 119249751(PPP1R12C)
SARA: 101539889(PPP1R12C)
SETR: 126028082(PPP1R12C)
LAV: 100669550(PPP1R12C)
TMU: 101355540
ETF: 101648322(PPP1R12C)
DNM: 101421478(PPP1R12C)
GAS: 123256107(PPP1R12C)
SHR: 116422717(PPP1R12C)
AFZ: 127557655
PCW: 110219818(PPP1R12C)
OAA: 100087416(PPP1R12C)
GGA: 107049646(PPP1R12C)
PCOC: 116239627(PPP1R12C)
CJO: 107307229(PPP1R12C)
NMEL: 110391351(PPP1R12C)
ASN: 102380217(PPP1R12C)
AMJ: 102559388(PPP1R12C)
CMY: 102934075(PPP1R12C)
CCAY: 125627872(PPP1R12C)
DCC: 119847380(PPP1R12C)
CPIC: 101937529
TST: 117888780(PPP1R12C)
CABI: 116834895(PPP1R12C)
MRV: 120388252(PPP1R12C)
ACS: 100561659(ppp1r12c)
ASAO: 132777901(PPP1R12C)
PVT: 110078487(PPP1R12C)
SUND: 121933309(PPP1R12C)
PBI: 103051816(PPP1R12C)
PMUR: 107282540(PPP1R12C) 107299194
CTIG: 120304495(PPP1R12C)
TSR: 106548413(PPP1R12C)
PGUT: 117669078(PPP1R12C)
APRI: 131197558(PPP1R12C)
PTEX: 113443480(PPP1R12C)
NSS: 113418524(PPP1R12C)
VKO: 123032162(PPP1R12C)
PMUA: 114608033(PPP1R12C)
PRAF: 128400032(PPP1R12C)
ZVI: 118094322(PPP1R12C)
HCG: 128329638(PPP1R12C)
GJA: 107125719(PPP1R12C)
STOW: 125444583(PPP1R12C)
EMC: 129338595(PPP1R12C)
XLA: 108696670 108697741
XTR: 734022(ppp1r12c)
RTEM: 120915347(PPP1R12C)
BBUF: 121001445(PPP1R12C)
BGAR: 122928652(PPP1R12C)
MUO: 115466553(PPP1R12C)
GSH: 117367827(PPP1R12C)
DRE: 570218(ppp1r12c)
SRX: 107710164 107716886
SANH: 107688807 107694908(ppp1r12c)
SGH: 107569470 107586341
CCAR: 109080602
CAUA: 113049905 113097407
CGIB: 127960072 128015469
PTET: 122347104(ppp1r12c)
LROH: 127166724(ppp1r12c)
OMC: 131542963(ppp1r12c)
PPRM: 120466936(ppp1r12c)
MAMB: 125278121(ppp1r12c)
CIDE: 127514576
IPU: 108273132(ppp1r12c)
IFU: 128615373(ppp1r12c)
PHYP: 113538332(ppp1r12c)
SMEO: 124400078(ppp1r12c)
TFD: 113634558(ppp1r12c)
TVC: 132844854(ppp1r12c)
AMEX: 103031099
CMAO: 118807925(ppp1r12c)
EEE: 113590831
CHAR: 105900223(ppp1r12c)
TRU: 101061089(ppp1r12c)
TFS: 130527297(ppp1r12c) 130535689(zmp:0000001167)
TNG: GSTEN00032501G001
LCO: 104920398(ppp1r12c)
NCC: 104956269(ppp1r12c)
TBEN: 117482399(ppp1r12c) 117491940(zmp:0000001167)
CGOB: 115009748 115013154
PGEO: 117447913(zmp:0000001167) 117458064(ppp1r12c)
GACU: 117538850(zmp:0000001167) 117562514(ppp1r12c)
EMAC: 134864362(ppp1r12c) 134876010(zmp:0000001167)
ELY: 117255537(ppp1r12c)
EFO: 125885748(ppp1r12c) 125887336(zmp:0000001167)
PLEP: 121942236(ppp1r12c)
SLUC: 116039650(ppp1r12c)
ECRA: 117948723(zmp:0000001167) 117959899(ppp1r12c)
ESP: 116694165 116704390
PFLV: 114559811 114571436(ppp1r12c)
GAT: 120825687(ppp1r12c)
PPUG: 119217679(ppp1r12c)
AFB: 129095602(ppp1r12c) 129108098(zmp:0000001167)
CLUM: 117732246(zmp:0000001167) 117741497(ppp1r12c)
PSWI: 130190351(ppp1r12c) 130195100(zmp:0000001167)
MSAM: 119899751(ppp1r12c)
SCHU: 122872832(ppp1r12c) 122875420(zmp:0000001167)
CUD: 121508793(ppp1r12c)
ALAT: 119017616(ppp1r12c) 119024340(zmp:0000001167)
MZE: 101469213(ppp1r12c)
ONL: 109194150(ppp1r12c)
OAU: 116331485(ppp1r12c)
OLA: 101168365 101174975
OML: 112152858(zmp:0000001167) 112157049(ppp1r12c)
CSAI: 133444123(zmp:0000001167) 133446908(ppp1r12c)
XMA: 102219491
XCO: 114144272
XHE: 116720491 116732153
PRET: 103463409
PFOR: 103133376 103141312
PLAI: 106952165 106964667
PMEI: 106921801 106933100
GAF: 122829052(ppp1r12c) 122835467(zmp:0000001167)
PPRL: 129359455(zmp:0000001167) 129367126(ppp1r12c)
CVG: 107085515(ppp1r12c)
CTUL: 119779348(ppp1r12c) 119787421(zmp:0000001167)
GMU: 124868649(ppp1r12c) 124885009(zmp:0000001167)
NFU: 107396436
KMR: 108251359(ppp1r12c)
ALIM: 106526908(ppp1r12c)
NWH: 119416463(zmp:0000001167) 119422710(ppp1r12c)
AOCE: 111575061(ppp1r12c)
MCEP: 125004646(ppp1r12c) 125014678(zmp:0000001167)
CSEM: 103384367
POV: 109627557(ppp1r12c)
SSEN: 122770728(ppp1r12c)
HHIP: 117759979(ppp1r12c)
HSP: 118116244(ppp1r12c)
SMAU: 118313263(ppp1r12c)
LCF: 108884541
SDU: 111217994
SLAL: 111660421
XGL: 120800716(ppp1r12c)
HCQ: 109521847
SSCV: 125969529 125970094(zmp:0000001167)
SBIA: 133502155(zmp:0000001167) 133506066(ppp1r12c)
PEE: 133402383(zmp:0000001167) 133403621(ppp1r12c)
PTAO: 133477459(ppp1r12c) 133478505(zmp:0000001167)
BPEC: 110173828(ppp1r12c)
MALB: 109956791(ppp1r12c)
BSPL: 114850795(ppp1r12c)
SJO: 128358455(zmp:0000001167) 128369813(ppp1r12c)
SASA: 100194922(pp12c) 106564933
STRU: 115177620 115196655 115208658
OTW: 112245504 112245575
OMY: 110485928 110493652
OGO: 124003006 124015272
ONE: 115103786 115125795 115142573
OKI: 109865734 109889359
OKE: 118364929 118389234
SALP: 111961231 112080742
SNH: 120032941 120066068
CCLU: 121531478 121533000 121534004
ELS: 105021605
SFM: 108918682
PKI: 111850734
AANG: 118215440(zmp:0000001167)
PSPA: 121305868(ppp1r12c)
ARUT: 117432319 117434907
PSEX: 120535677(zmp:0000001167) 120541885(ppp1r12c)
LCM: 102356480(PPP1R12C)
RTP: 109913115
CPLA: 122542178
HOC: 132831243
LERI: 129706007 129713999
FOC: 113206271
UDV: 129220838
SDM: 118195112
 » show all
Reference
PMID:11399775
  Authors
Tan I, Ng CH, Lim L, Leung T
  Title
Phosphorylation of a novel myosin binding subunit of protein phosphatase 1 reveals a conserved mechanism in the regulation of actin cytoskeleton.
  Journal
J Biol Chem 276:21209-16 (2001)
DOI:10.1074/jbc.M102615200
  Sequence
[hsa:54776]
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