KEGG   ORTHOLOGY: K17646
Entry
K17646                      KO                                     
Symbol
VBS
Name
5'-oxoaverantin cyclase / versicolorin B synthase [EC:4.2.1.142 4.2.1.143]
Pathway
map00254  Aflatoxin biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00937  Aflatoxin biosynthesis, malonyl-CoA => aflatoxin B1
Reaction
R10402  versiconal hydro-lyase (versicolorin-B forming)
R10475  5'-oxoaverantin hydro-lyase [(1'S,5'S)-averufin forming]
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00254 Aflatoxin biosynthesis
    K17646  VBS; 5'-oxoaverantin cyclase / versicolorin B synthase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.142  5'-oxoaverantin cyclase
     K17646  VBS; 5'-oxoaverantin cyclase / versicolorin B synthase
    4.2.1.143  versicolorin B synthase
     K17646  VBS; 5'-oxoaverantin cyclase / versicolorin B synthase
Other DBs
GO: 0046572
Genes
PAN: PODANSg8556
PBEL: QC761_207270
PPSD: QC762_207270
PPSP: QC763_207270
PPSA: QC764_207270
PGRI: PgNI_01190
CHIG: CH63R_13456
ANI: ANIA_07812
AOR: AO090026000028
AFV: AFLA_006289
AG: AAC49318(vbs)
 » show all
Reference
  Authors
Sakuno E, Wen Y, Hatabayashi H, Arai H, Aoki C, Yabe K, Nakajima H
  Title
Aspergillus parasiticus cyclase catalyzes two dehydration steps in aflatoxin biosynthesis.
  Journal
Appl Environ Microbiol 71:2999-3006 (2005)
DOI:10.1128/AEM.71.6.2999-3006.2005
  Sequence
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