KEGG   ORTHOLOGY: K17830
Entry
K17830                      KO                                     
Symbol
GGR
Name
digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
Pathway
map00564  Glycerophospholipid metabolism
map01110  Biosynthesis of secondary metabolites
Reaction
R10325  2,3-bis-(O-phytanyl)-sn-glycerol 1-phosphate:NAD+ oxidoreductase
R10326  2,3-bis-(O-phytanyl)-sn-glycerol 1-phosphate:NADP+ oxidoreductase
R10331  2,3-bis-(O-phytanyl)-sn-glycero-phospholipid:ferredoxin oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    K17830  GGR; digeranylgeranylglycerophospholipid reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.101  2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H]
     K17830  GGR; digeranylgeranylglycerophospholipid reductase
   1.3.7  With an iron-sulfur protein as acceptor
    1.3.7.11  2,3-bis-O-geranylgeranyl-sn-glycero-phospholipid reductase
     K17830  GGR; digeranylgeranylglycerophospholipid reductase
Genes
PMEX: H4W19_05940
PDD: MNQ95_14045
LAB: LA76x_2426
LAQ: GLA29479_2709
LGU: LG3211_2789
LEZ: GLE_2795
LEM: LEN_2236
LMB: C9I47_1426
LYT: DWG18_07380
LYJ: FKV23_07190
LSX: H8B22_00975
LHX: LYSHEL_30720
LCAS: LYSCAS_30690
THES: FHQ07_02060
TBV: H9L17_15740
HHC: M911_11185
EBS: ECTOBSL9_0276
TGR: Tgr7_2205
TKM: TK90_0643
TVR: TVD_10595
APRS: BI364_13760
SVA: SVA_2992
ACII: C4901_12925
ATY: A9R16_004045
CGD: CR3_0650(fixC)
VPE: Varpa_3679
VBO: CKY39_19940
VAM: C4F17_03155
SDR: SCD_n00804
SULF: CAP31_01895
SPLB: SFPGR_29360
SNIV: SFSGTM_27200
URU: DSM104443_00527
BEBA: BWI17_02380
HDN: Hden_0684
RVA: Rvan_3542
FIL: BN1229_v1_0189
FIY: BN1229_v1_0193
CMAR: IMCC12053_1371
RHC: RGUI_1289
AMYL: QBD29_00465
AFR: AFE_2544
AFE: Lferr_2172
ACU: Atc_2341
ACZ: Acaty_c2184
AFI: Acife_2465
AFJ: AFERRID_05040
AFP: K1Y48_09080
DOL: Dole_0399
DTI: Desti_0238
DBR: Deba_3038
CBK: CLL_A1369 CLL_A1370
CLB: Clo1100_3094 Clo1100_3095
CLT: CM240_1758 CM240_1759
HSC: HVS_14075
CCE: Ccel_1057 Ccel_1058
RHER: EHE19_004620 EHE19_004625
RPAY: P0092_17605
SALQ: SYNTR_0780
DOR: Desor_4339
PTH: PTH_0378(FixC)
DKU: Desku_2287
FWA: DCMF_14630
DGI: Desgi_1545
TEX: Teth514_0218 Teth514_0219
THX: Thet_0258 Thet_0259
TPD: Teth39_1995
TIT: Thit_0239 Thit_0240
TMT: Tmath_0322 Tmath_0323
TBO: Thebr_2044
TWI: Thewi_0279
TKI: TKV_c02330
TPZ: Tph_c09910(bchP)
TXY: Thexy_2059
TSH: Tsac_0175
TEP: TepRe1_0379
TAE: TepiRe1_0421
BACG: D2962_14315
TOC: Toce_0251
NTH: Nther_1774
KME: H0A61_01699
STED: SPTER_30020(kmo)
CALK: HUE98_00670
BALA: DSM104299_03518
PARN: NBH00_13915
PBAJ: LRS13_19280
PMT: PMT_0686
PMF: P9303_15361
PMJ: P9211_08531
CSN: Cyast_1222
MAR: MAE_31260
MPK: VL20_5387
MIQ: B5D77_03105
MVZ: myaer102_06730
CYC: PCC7424_4688
CYJ: Cyan7822_4141
PAGH: NIES204_25480
PPSU: NO713_00666
OXY: HCG48_06915
MVAG: D0A34_03765
OAC: Oscil6304_0659
ONI: Osc7112_3504
MIC: Mic7113_1946
GEI: GEI7407_1050
PLP: Ple7327_4278
ABAT: CFX1CAM_1448
KBS: EPA93_17655
KBB: ccbrp13_22200
PNL: PNK_0017
PND: Pla175_09780
FSU: Fisuc_0330 Fisuc_2122
FSC: FSU_0745 FSU_2657
POM: MED152_04120
POB: LPB03_12595 LPB03_16045
PRN: BW723_10930
POLA: BXQ17_11625
POA: CW731_11625
PLIT: K8354_10745
PBAT: JL193_08020
PCEA: J3359_02050
IAL: IALB_0329
HYA: HY04AAS1_0807
HHO: HydHO_0802
HYS: HydSN_0819
TAL: Thal_0865
TRD: THERU_04165
KPF: IX53_05590
CPO: COPRO5265_1158
CABY: Cabys_957
DTH: DICTH_0710
DTU: Dtur_0864
BANA: BARAN1_0630
BIH: BIP78_0559
MJA: MJ_0532
MFE: Mefer_0023 Mefer_0586
MVU: Metvu_0248 Metvu_0470
MFS: MFS40622_0302 MFS40622_0533
MIF: Metin_0313
MJH: JH146_0202
MESG: MLAUSG7_0668
MESA: MLASG1_0156
MIG: Metig_0018
MMP: MMP0388
MMQ: MmarC5_1250
MMX: MmarC6_0522
MMZ: MmarC7_1386
MMD: GYY_02010
MMAK: MMKA1_04070
MMAO: MMOS7_04030
MMAD: MMJJ_06490
MAE: Maeo_1307
MVN: Mevan_1375
MVO: Mvol_1689
MOK: Metok_0574
METF: CFE53_00320
MTH: MTH_1718 MTH_277
MMG: MTBMA_c02950 MTBMA_c07260 MTBMA_c11210
MWO: MWSIV6_0259 MWSIV6_0692 MWSIV6_1100
MTEE: MTTB_09190 MTTB_14720
METC: MTCT_0239 MTCT_1570
METE: tca_00257(menJ_1) tca_01663(menJ_2)
METZ: METMT2_0572 METMT2_0721 METMT2_1561
METK: FVF72_00920 FVF72_03085
MTHM: FZP57_01175 FZP57_03320 FZP57_05215
METJ: FZP68_06180 FZP68_08325
MST: Msp_0758 Msp_0874 Msp_1062 Msp_1307 Msp_1320
METB: AW729_08940 AW729_09050 AW729_10575 AW729_10930
MEIS: PXD04_00860 PXD04_02310 PXD04_02685
MRU: mru_1341 mru_1441 mru_1471
MSI: Msm_1701
MEB: Abm4_0728 Abm4_1169
MMIL: sm9_1381
MEYE: TL18_04135
MOL: YLM1_0823 YLM1_0971
MARO: MarbSA_00110
METV: K4897_00040
MEL: Metbo_0471 Metbo_2033 Metbo_2366
MEW: MSWAN_0290 MSWAN_0605 MSWAN_1925
METH: MBMB1_0335 MBMB1_0639 MBMB1_1556 MBMB1_1827
MFC: BRM9_0792 BRM9_1599 BRM9_1933 BRM9_2158
MFI: DSM1535_0120 DSM1535_0754 DSM1535_1097 DSM1535_2293
MCUB: MCBB_0308 MCBB_0619 MCBB_1812
MSUB: BK009_01280 BK009_06770 BK009_11855
METN: BK008_02415 BK008_07495 BK008_09685
METT: CIT01_01350 CIT01_04015 CIT01_04025 CIT01_07320 CIT01_10150
METO: CIT02_03745 CIT02_05170 CIT02_08440 CIT02_10165
MEME: HYG87_07945 HYG87_10880
MFEG: GCM10025860_04480 GCM10025860_12360 GCM10025860_16550
MFV: Mfer_0516 Mfer_1222
MKA: MK1443 MK1645
AFU: AF_0464
AFG: AFULGI_00004710
APO: Arcpr_0713
AVE: Arcve_2050
AST: Asulf_00147 Asulf_01626
FPL: Ferp_0366 Ferp_1444
GAC: GACE_0072 GACE_0595
GAH: GAH_00300 GAH_00353 GAH_01689
PFU: PF0097
PFI: PFC_07720
PHO: PH0181(PH0181)
PAB: PAB0109(bchP)
PYN: PNA2_0702
PYA: PYCH_16330
PYS: Py04_0252
PYC: TQ32_00315
TKO: TK1088
TON: TON_0316
TGA: TGAM_1305
TSI: TSIB_0988
TBA: TERMP_00654
THE: GQS_03690
THA: TAM4_1982
THM: CL1_0388
TLT: OCC_08470
THS: TES1_0613
TNU: BD01_0182
TEU: TEU_06540
TGY: X802_10265
THV: ADU37_CDS08620
TCH: CHITON_0316
TPEP: A0127_09785
TPIE: A7C91_07555
TGG: A3K92_03945
TCE: A3L02_00260
TBS: A3L01_02245
THH: CDI07_02200
TSL: A3L11_06065
TTD: A3L14_03705
TPRF: A3L09_05905
TRL: A3L10_04285
TPAF: A3L08_04750
THY: A3L12_01970
TIC: FH039_04700
TCQ: TIRI35C_0673
THEM: FPV09_04700
THEI: K1720_08110
PPAC: PAP_07210
MBA: Mbar_A3422
MBY: MSBRM_1245 MSBRM_2785
MBW: MSBRW_1312
MBAR: MSBR2_1164 MSBR2_2742
MBAK: MSBR3_1297 MSBR3_2679
MAC: MA_1484 MA_2893 MA_3894 MA_4421
MMA: MM_0718 MM_2499 MM_3299
MMAZ: MmTuc01_0739 MmTuc01_2550 MmTuc01_3399
MMJ: MSMAS_0599 MSMAS_1387 MSMAS_2202
MMAC: MSMAC_0600 MSMAC_2252 MSMAC_2749
MVC: MSVAZ_0959 MSVAZ_1325 MSVAZ_1805
MEK: MSKOL_0928 MSKOL_1264 MSKOL_1782
MLS: MSLAZ_1440 MSLAZ_1542 MSLAZ_2928
METM: MSMTP_0646 MSMTP_0954 MSMTP_1509
MEF: MSWH1_1330 MSWH1_1478 MSWH1_1898
MEQ: MSWHS_1414 MSWHS_1853 MSWHS_3173
MSJ: MSSAC_1463 MSSAC_2883 MSSAC_4107
MSZ: MSSIH_1494 MSSIH_2538 MSSIH_3643
MSW: MSSIT_1552 MSSIT_2581 MSSIT_3698
MTHR: MSTHT_0217 MSTHT_0358 MSTHT_1727 MSTHT_2311
MTHE: MSTHC_0364 MSTHC_0514 MSTHC_0969 MSTHC_1561
MHOR: MSHOH_0251 MSHOH_1697 MSHOH_2811
MFZ: AOB57_000445 AOB57_001340 AOB57_003910 AOB57_007820
MBU: Mbur_0303 Mbur_0369 Mbur_0939 Mbur_1077 Mbur_1308
MMET: MCMEM_0833 MCMEM_0997 MCMEM_1441 MCMEM_1598 MCMEM_1755
MELO: J7W08_02385 J7W08_03355 J7W08_05920 J7W08_06945 J7W08_07805
MMH: Mmah_0579 Mmah_0675 Mmah_1258 Mmah_1613
MHAZ: BHR79_00515 BHR79_05660 BHR79_07245 BHR79_10225
MPOT: BKM01_01750 BKM01_07890 BKM01_09925
MEV: Metev_0262 Metev_0801 Metev_1607 Metev_1731
MZH: Mzhil_0235 Mzhil_0513 Mzhil_0683 Mzhil_1608
MPY: Mpsy_0099 Mpsy_1026 Mpsy_1467 Mpsy_2554
MZI: HWN40_01470 HWN40_03330 HWN40_05930 HWN40_09670
MMAV: RE476_00450
MSEB: RE474_10185
MHZ: Metho_0239 Metho_0947 Metho_1579 Metho_1933
MEHF: MmiHf6_00880(kmo)
MEES: MmiEs2_09160(thi4_2) MmiEs2_09170(thi4_3)
MTP: Mthe_0044 Mthe_0513 Mthe_0671 Mthe_0714
MCJ: MCON_1147 MCON_3250 MCON_3296
MHI: Mhar_0556 Mhar_1078 Mhar_1156 Mhar_2172
MHU: Mhun_1123
MRTJ: KHC33_08510
MLA: Mlab_0431
MEM: Memar_0506 Memar_1711
MBG: BN140_1582
MEMA: MMAB1_2023
MCHK: MchiMG62_06300
MSUM: OH143_09245
MRC: R6Y96_10195
MPI: Mpet_1752
MEND: L6E24_01525
MEFW: F1737_03510
MAQE: RJ40_04645
MFK: E2N92_04850
MOU: OU421_10180
MESB: L1S32_01385
MANQ: L1994_04690
MBN: Mboo_1945
MFO: Metfor_1011
MPL: Mpal_0962
MPD: MCP_0504 MCP_1168 MCP_1480
MEZ: Mtc_0895(bchP) Mtc_1643 Mtc_1724
RCI: RCIX2051(bchP) RCIX2708
HAL: VNG_0468C
HSL: OE_1699R
HANR: LJ422_01955
HDL: HALDL1_06480
HHB: Hhub_1531
HAGS: JT689_03235
HABO: JRZ79_01735
HNO: LT974_03030
HLU: LT972_10470
HALH: HTSR_0966
HHSR: HSR6_0997
HSU: HLASF_0746
HSF: HLASA_0743
SALR: FQU85_11230
HALR: EFA46_006370 EFA46_006470
HJE: HacjB3_14420
HDO: MUK72_09380
HALX: M0R89_10965
HAXZ: M0R88_11400
HAYC: NGM10_04900
HAXY: NGM07_16955
SALI: L593_01650
SAIM: K0C01_10790
HARA: AArcS_1790(fixC3)
HMA: rrnAC0726
HHI: HAH_1373
HHN: HISP_07025
HAB: SG26_14865
HTA: BVU17_06685
HALJ: G9465_08440 G9465_08805 G9465_20450
HSIN: KDQ40_06605
NPH: NP_4564A
NMO: Nmlp_2334 Nmlp_3608
NHO: HWV23_05715
NSAL: HWV07_05475
HUT: Huta_0881 Huta_1007 Huta_2954
HTI: HTIA_0743 HTIA_2555
HALA: Hrd1104_04765 Hrd1104_09045
HMU: Hmuk_1955 Hmuk_2206 Hmuk_3091 Hmuk_3127
HALZ: E5139_02700 E5139_02875 E5139_12890 E5139_14170
HALL: LC1Hm_1280 LC1Hm_1619(fixC) LC1Hm_2428(fixC3) LC1Hm_2469(fixC4)
HAZP: GBQ70_02700 GBQ70_12905 GBQ70_14185
HALI: BV210_03410
HSN: DV733_10365
HDS: HSR122_0270(fixC)
HRR: HZS55_18830 HZS55_20705
HPEL: HZS54_21655 HZS54_22270 HZS54_24195
HLT: I7X12_15485 I7X12_16545 I7X12_17600
HARC: HARCEL1_04790
SSAI: N0B31_03370
HWA: HQ_1534A
HWC: Hqrw_1635 Hqrw_3314
HVO: HVO_1799
HME: HFX_1905(fixC)
HGI: ABY42_08860
HALE: G3A49_12170
HLS: KU306_03510
HLN: SVXHx_2785(ggr)
HBO: Hbor_11300
HAQ: DU484_09565 DU484_17775
HAJ: DU500_00815 DU500_09815
HAER: DU502_06905 DU502_07185 DU502_16565
HRA: EI982_07520 EI982_14380
HLM: DV707_07230
HALM: FCF25_11425
HLA: Hlac_0926
HALP: DOS48_03545
HALB: EKH57_07685
HEZZ: EO776_04760
HALQ: Hrr1229_002660
HSS: J7656_12430
HSAI: HPS36_02425
HAZZ: KI388_02310
SRUB: C2R22_05450
HAE: halTADL_1048
HALN: B4589_000260
HALG: HUG10_08475
HALU: HUG12_17860
HDF: AArcSl_1381 AArcSl_1813
HAAA: AArcCO_0174(fixC)
HAH: Halar_0855
HTU: Htur_1377 Htur_3081
HSAL: JMJ58_01855 JMJ58_05545 JMJ58_12995 JMJ58_22355
HAKZ: J0X25_02870 J0X25_13780
NMG: Nmag_0668 Nmag_1523 Nmag_2507 Nmag_2778
HXA: Halxa_3925 Halxa_3960
NAT: NJ7G_0898 NJ7G_2427
NPE: Natpe_0646 Natpe_1962 Natpe_3244
NVR: FEJ81_03545
NPL: FGF80_01135 FGF80_07435
NAY: HYG81_07440
HALY: HYG82_09140 HYG82_16990
HJT: DVR14_12450
HLO: J0X27_13130
NGE: Natgr_0786 Natgr_1266 Natgr_3103
HRU: Halru_1246 Halru_2474
SAWL: NGM29_01025
HALV: NGM15_10625
NOU: Natoc_0699 Natoc_2139 Natoc_4277
HLR: HALLA_08655 HALLA_13160 HALLA_17630
HLC: CHINAEXTREME15935 CHINAEXTREME19570
NAJ: B1756_02305 B1756_04290 B1756_12495
NAG: AArcMg_1023 AArcMg_2971 AArcMg_3119
NAN: AArc1_0731 AArc1_2601 AArc1_3025
NARA: QQ977_14385
NBG: DV706_00945 DV706_09380 DV706_16325 DV706_19090
NAS: GCU68_02695 GCU68_12755
HDA: BB347_05735 BB347_10350 BB347_10530
NAC: AQV86_03970
MELU: MTLP_05820 MTLP_05840 MTLP_09940
MEAM: MU439_04990
MEAE: QEN48_05175
TAC: Ta0516
TVO: TVG1046096(TVG1046096) TVG1579590(TVG1579590)
PTO: PTO0568 PTO0896
FAC: FACI_IFERC01G0166
FAI: FAD_1079
CDIV: CPM_0295 CPM_0485 CPM_0894
TAR: TALC_00223 TALC_00435 TALC_00774
MAX: MMALV_02090 MMALV_03590 MMALV_08730
MER: MMINT_02130 MMINT_12590 MMINT_13170 MMINT_17750
MEAR: Mpt1_c01650 Mpt1_c12530
MEUZ: KRP56_01915
MARC: AR505_0892 AR505_1433 AR505_1618
ABI: Aboo_0578
ACF: AciM339_0374 AciM339_0468
SMR: Smar_1462
DKA: DKAM_0159
DFD: Desfe_0234
DMU: Desmu_0290
TAG: Tagg_0378
THG: TCELL_1246
HBU: Hbut_1257
STO: STK_04940
SOH: D1869_02295
SSO: SSO2353
SOL: Ssol_0166
SSOA: SULA_0158
SSOL: SULB_0159
SSOF: SULC_0158
SSHI: J5U23_01149
SCAS: SACC_19360
SIS: LS215_0182
SIA: M1425_0151
SIM: M1627_0151
SID: M164_0170
SIY: YG5714_0155
SIN: YN1551_2754
SII: LD85_0155
SIH: SiH_0155
SIR: SiRe_0151
SIC: SiL_0142
SULA: BFU36_10465
SULE: GFS03_02305
SULO: GFS33_08920
MSE: Msed_0681
MEMJ: MJ1HA_0791
MCN: Mcup_1399
MHK: DFR87_03150
MPRU: DFR88_03175
MTEN: GWK48_08960
MJN: MjAS7_1447
AHO: Ahos_2154
AMAN: B6F84_03335
ABRI: DFR85_06060
ASUL: DFR86_03340
AAMB: D1866_05750
ACIH: HS5_09650
SACD: HS1genome_0804
SAZO: D1868_10400
STEP: IC006_2737
SMET: RQ359_001719
CMA: Cmaq_0840
VDI: Vdis_1715
VMO: VMUT_2242
TPE: Tpen_0114 Tpen_0718
THB: N186_01490 N186_04950
TCB: TCARB_0050 TCARB_1382
THF: MA03_00905 MA03_06135
THEL: IG193_04155 IG193_06980
ACIA: SE86_02030
FFO: FFONT_1180
NMR: Nmar_0631
NIR: NSED_03245
NKR: NKOR_03230
NID: NPIRD3C_1636
NIN: NADRNF5_0722 NADRNF5_1519
NIW: Nisw_01750
NCL: C5F47_05915
NOX: C5F49_05755 C5F49_06640
NUE: C5F50_04660
NIP: NsoK4_05210
NZT: NZOSNM25_001364
NCT: NMSP_0453 NMSP_1055
NIC: DSQ20_03360
NGA: Ngar_c10460 Ngar_c11500 Ngar_c18750
NVN: NVIE_003360 NVIE_011700
NEV: NTE_01655 NTE_02579
TAA: NMY3_01977 NMY3_02141 NMY3_02989
NFN: NFRAN_0449 NFRAN_2927
NCV: NCAV_0324
CSY: CENSYa_0520 CENSYa_1317
CSU: CSUB_C1349 CSUB_C1610
NBV: T478_0510 T478_0975
TAH: SU86_000125 SU86_003010
NIU: DSQ19_03605
NDV: NDEV_0107 NDEV_1206
KCR: Kcr_0058 Kcr_1359
BARC: AOA65_1634
FLT: Sv326_0975
LOKI: Lokiarch_51240
LOB: NEF87_004200
PSYT: DSAG12_02297
AGW: QT03_C0001G0827
 » show all
Reference
PMID:16788058
  Authors
Nishimura Y, Eguchi T
  Title
Biosynthesis of archaeal membrane lipids: digeranylgeranylglycerophospholipid reductase of the thermoacidophilic archaeon Thermoplasma acidophilum.
  Journal
J Biochem 139:1073-81 (2006)
DOI:10.1093/jb/mvj118
  Sequence
[tac:Ta0516]
Reference
PMID:17288560
  Authors
Murakami M, Shibuya K, Nakayama T, Nishino T, Yoshimura T, Hemmi H
  Title
Geranylgeranyl reductase involved in the biosynthesis of archaeal membrane lipids in the hyperthermophilic archaeon Archaeoglobus fulgidus.
  Journal
FEBS J 274:805-14 (2007)
DOI:10.1111/j.1742-4658.2006.05625.x
  Sequence
[afu:AF_0464]
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