KEGG   ORTHOLOGY: K18317
Entry
K18317                      KO                                     
Symbol
cpmB, carB
Name
carboxymethylproline synthase [EC:2.3.1.226]
Pathway
map00332  Carbapenem biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map02024  Quorum sensing
Module
M00675  Carbapenem-3-carboxylate biosynthesis, pyrroline-5-carboxylate + malonyl-CoA => carbapenem-3-carboxylate
Reaction
R10485  malonyl-CoA:(S)-1-pyrroline-5-carboxylate malonyltransferase (cyclizing)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00332 Carbapenem biosynthesis
    K18317  cpmB, carB; carboxymethylproline synthase
 09140 Cellular Processes
  09145 Cellular community - prokaryotes
   02024 Quorum sensing
    K18317  cpmB, carB; carboxymethylproline synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.226  carboxymethylproline synthase
     K18317  cpmB, carB; carboxymethylproline synthase
Other DBs
COG: COG1024
Genes
PROD: PCO85_15485
SERA: Ser39006_009925
SERQ: CWC46_09920
PARI: I2D83_01755
PPAV: LOZ86_02765
PCAC: OI450_17090
PACB: M9782_00170
DZE: Dd1591_0212
DAQ: DAQ1742_04175(cpmB)
PAO: Pat9b_5316
PLU: plu0183(cpmB)
PRG: RB151_027390(echA8)
VSR: Vspart_02936(echA8)
PFT: JBW_01239
 » show all
Reference
  Authors
Stapon A, Li R, Townsend CA
  Title
Carbapenem biosynthesis: confirmation of stereochemical assignments and the role of CarC in the ring stereoinversion process from L-proline.
  Journal
J Am Chem Soc 125:8486-93 (2003)
DOI:10.1021/ja034248a
LinkDB

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