KEGG   ORTHOLOGY: K18351
Entry
K18351                      KO                                     
Symbol
vanSAc
Name
two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
Pathway
map01502  Vancomycin resistance
map02020  Two-component system
Module
M00651  Vancomycin resistance, D-Ala-D-Lac type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
  09183 Protein families: signaling and cellular processes
   02022 Two-component system
    K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
   01504 Antimicrobial resistance genes
    K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.13  Protein-histidine kinases
    2.7.13.3  histidine kinase
     K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
Protein kinases [BR:ko01001]
 Histidine kinases
  OmpR family
   K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
Two-component system [BR:ko02022]
 OmpR family
  VanS-VanR (actinomycete type vancomycin resistance)
   K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
Antimicrobial resistance genes [BR:ko01504]
 Gene sets
  Vancomycin resistance modules
   Vancomycin resistance, D-Ala-D-Lac type
    K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
Other DBs
COG: COG0642
GO: 0000155
Genes
MESP: C1M53_06630
LLU: AKJ09_02402
MMAT: MMAGJ_17070
MBOK: MBOE_16170
MFG: K6L26_29335
MGO: AFA91_06345
MSEN: K3U95_02375
CGT: cgR_0540
CGS: C624_02775
CGG: C629_02775
CUR: cu0642(tcsS3)
CUA: CU7111_0631(tcsS3)
CII: CIMIT_04710
CUV: CUREI_04465
CSTA: CSTAT_08730
CGV: CGLAU_04625(cusS)
CSTR: CBE89_03740
CLUJ: IAU68_04305
CWK: IA203_04775
CCOY: CCOY_04705(prrB)
CHAD: CHAD_04955(tcrY1)
CAQM: CAQUA_07140(tcrY2)
CFOU: CFOUR_04095(cusS)
CAFE: CAFEL_04015(prrB)
CGOI: CGOTT_04610(tcrY1)
CPYR: CYJ47_11170
CRIE: AK829_05280
NFA: NFA_6940
NFR: ERS450000_03417(baeS)
NBR: O3I_015645
NTP: CRH09_24955 CRH09_30825
NOZ: DMB37_03915
NOD: FOH10_18600
NAH: F5544_23940
NWL: NWFMUON74_26200
NIE: KV110_10645
TPR: Tpau_0521
TOY: FO059_01065
SCO: SCO3589(SCH66.10c)
SGR: SGR_275
SGB: WQO_33205
SANL: KZO11_37250
SRC: M271_02035
SSOI: I1A49_01635
SBH: SBI_09519
SVE: SVEN_6833
SDV: BN159_0591
SLV: SLIV_20350
SVT: SVTN_32450
SXI: SXIM_13630 SXIM_54590
STRC: AA958_28395
SPRI: SPRI_1962
SPAV: Spa2297_16660
SCLF: BB341_22520
SALW: CP975_31545
SGM: GCM10017557_80010
SCAD: DN051_03195
SPHW: NFX46_17035
SLS: SLINC_1092 SLINC_1848
SSIA: A7J05_01450
SVU: B1H20_33820
SLAU: SLA_2438
SALF: SMD44_04674
SFK: KY5_0087
SNZ: DC008_14115
SGE: DWG14_06772(baeS_3)
SCYA: EJ357_46335
SNQ: CP978_27460
SPAD: DVK44_32100
SFY: GFH48_02780
SAQU: EJC51_03765 EJC51_04145
SBY: H7H31_16200
SRIM: CP984_39890
SPHV: F9278_37080
SPAC: B1H29_35910
SCHA: CP983_42260
SGX: H4W23_38845
SCOE: CP976_02300
SBAT: G4Z16_05555
SSPB: CP982_05210 CP982_31345
SATA: C5746_15280
SHUN: DWB77_02451(baeS)
SHAR: HUT13_07520
SFEU: IM697_16505
SCAL: I6J39_33555
SROI: IAG44_39610
SXN: IAG42_06505
SHK: J2N69_01865
SACT: DMT42_35875
SLF: JEQ17_01095 JEQ17_11730
SAOV: G3H79_40170
SDUR: M4V62_41780
SYAN: NRK68_00220
STAA: LDH80_01980
SCAE: IHE65_05525
SSPN: LXH13_01015 LXH13_33520
SCIR: STRCI_007802
SXT: KPP03845_104341(tcrY_3)
SLON: LGI35_00730
SDRZ: NEH16_00885
SARG: HKX69_30385
SCOA: QU709_40325 QU709_45485
SFP: QUY26_18065
STTN: BSL84_01230
SINN: ABB07_36970
STRZ: OYE22_15945
KIS: HUT16_12475
YIA: LO772_35440
ABRY: NYE86_22050
AGLA: OIE69_40650
LXL: KDY119_02009
PSIC: J4E96_06995 J4E96_09260
LXX: Lxx22000(cutS)
MTS: MTES_0052
MIM: AKG07_14440
MIO: AOA12_11715
MIX: AB663_001133
MIP: AXH82_08270
MPAL: BO218_06375
MIH: BJP65_02470
MICR: BMW26_01495
MFOL: DXT68_01605
MOO: BWL13_02831(tcrY_5)
MLV: CVS47_02386(baeS_2)
MWA: E4K62_07335
MSED: E3O41_07835
MOY: CVS54_00403(tcrY_1)
MCAW: F6J84_08970
MLZ: F6J85_07020
MRN: K8F61_12795
MICS: C1N74_04710
MBIN: LXM64_01835 LXM64_15125
MLIQ: NMQ05_01425
MTEC: OAU46_09580
MPAO: IZR02_01565
MAZA: NFX31_00835
MARK: QUC20_04515
RTN: A6122_0296
RRY: C1O28_00065
RIA: C7V51_10870
RTE: GSU10_00910
MVD: AWU67_07985
FRP: AX769_07725
AGY: ATC03_11875 ATC03_14850
AGF: ET445_10590
ASOI: MTP13_07495
CART: PA27867_3641
CPHY: B5808_17910
MSPO: KXZ72_08800
PLAP: EAO79_01050 EAO79_07970
LEB: G7066_05545
LVI: G7068_14870
LLUT: K1X41_08205
LARI: KI794_00070
LALL: MUN78_10645
LRP: MUN76_01680
LTN: KVY00_14765
AGG: C1N71_03545
HEH: L3i23_05610
AGX: AGREI_3191
ARE: AL755_06815
AWW: G8758_12115
AKO: N9A08_01400
GAR: AOZ07_13010
GCR: GcLGCM259_2668
MLY: CJ228_005705
AUL: DCC27_010090
AIG: QDX25_10095
BRX: BH708_10785
HMM: R3I40_05140
LMOI: VV02_02725
XCE: Xcel_1425
XYL: ET495_16455
XYA: ET471_12860
SKE: Sked_26830
CFI: Celf_1889
CIRA: LFM56_03725
OEK: FFI11_006460
PHW: G7075_00560
SERW: FY030_05315
BLUT: EW640_11540
BCAU: I6G59_17630
HALT: IM660_06620 IM660_06715
RHAL: LQF10_12945 LQF10_13470
RSUA: LQF12_10425
MPH: MLP_00340
MIK: FOE78_00310
MICG: GJV80_21410
TDF: H9L22_00860
NBE: Back2_27460
NARO: CFH99_24335
PSIM: KR76_22005
MUZ: H4N58_14060
SGRG: L0C25_10515
KFL: Kfla_3624
KQI: F1D05_26450
KSL: OG809_06690 OG809_30970 OG809_31040
NDA: Ndas_4943
NAL: B005_0147
NFE: HUT17_02590
NEC: KGD82_08720
NAKE: KGD83_27070
NCG: KGD84_02480 KGD84_09275
STRR: EKD16_24285(phoR)
SNAH: OUQ99_08300
ACTW: F7P10_09875
AGRA: AGRA3207_002876 AGRA3207_003206
ACIR: OG979_09870
SPIQ: OHA34_26505
ACTQ: OG417_51660
SRO: Sros_4755
NOW: GBF35_48600
FRE: Franean1_7134
AMD: AMED_8142 AMED_8287
AMN: RAM_41825 RAM_42555
AMM: AMES_8018 AMES_8161
AMZ: B737_8019 B737_8162
AMYC: CU254_05715
AAB: A4R43_21415
AMYY: YIM_36555(czcS)
APRT: MUY14_04900
ATHM: L1857_33125
PDX: Psed_6412
PHH: AFB00_19615
PAUT: Pdca_06120
PBRO: HOP40_21925
APRE: CNX65_22455
AMI: Amir_4513
SESP: BN6_49740
SSYI: EKG83_05365
KAL: KALB_1169
KUT: JJ691_70630
KBU: Q4V64_46390
KPHY: AOZ06_08695 AOZ06_30195
LED: BBK82_06950
AHM: TL08_02710 TL08_03385
ACTI: UA75_02670 UA75_19685
ACAD: UA74_02665 UA74_19195
AHG: AHOG_17395(tcrY2)
ACTU: Actkin_02320(baeS_1)
CROS: N8J89_03415
UME: RM788_01990
MCAB: HXZ27_24365
MSAG: GCM10017556_02050
MFEU: H1D33_06070
AMS: AMIS_51750
AFS: AFR_19475
AIH: Aiant_83680
AOU: ACTOB_006497
PSUU: Psuf_008110
ATL: Athai_15790
ASER: Asera_58780
DVC: Dvina_16575 Dvina_26180
DAUR: Daura_13335
DMAT: Dmats_21710
CCAZ: COUCH_31260
CAI: Caci_5789
SNA: Snas_6029
GLY: K3N28_22505
TPEC: HLG82_10055
AOS: AXE84_05780
ARD: AXF14_03435
ACTP: B6G06_00650
ACTO: C3V41_11975
ANE: ATCC27039_25320
ASLA: NCTC11923_00130(baeS_1)
AVC: NCTC10951_02506(baeS_3)
AMAM: HPC72_09420
AREP: ID810_00905
AMAS: QU670_01260
ACAP: MANAM107_07480
AUO: R3I39_04070
BBP: BBPR_1463
BBI: BBIF_1409
BBF: BBB_1442(cutS)
EKE: EK0264_15880
BSOL: FSW04_08040
BALA: DSM104299_02089(cusS)
CWO: Cwoe_0519 Cwoe_1411
SBAE: DSM104329_00640(sasA_1)
IAM: HC251_12740
DHI: LH044_08555
MCAO: IT6_05480
 » show all
Reference
PMID:15130128
  Authors
Hong HJ, Hutchings MI, Neu JM, Wright GD, Paget MS, Buttner MJ
  Title
Characterization of an inducible vancomycin resistance system in Streptomyces coelicolor reveals a novel gene (vanK) required for drug resistance.
  Journal
Mol Microbiol 52:1107-21 (2004)
DOI:10.1111/j.1365-2958.2004.04032.x
  Sequence
[sco:SCO3589]
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