KEGG ORTHOLOGY: K18660

ORTHOLOGY: K18660

Entry

K18660                      KO

Symbol

ACSF3

Name

malonyl-CoA/methylmalonyl-CoA synthetase [EC:6.2.1.76 6.2.1.-]

Pathway

map00061

Fatty acid biosynthesis

map00280

Valine, leucine and isoleucine degradation

map01100

Metabolic pathways

map01212

Fatty acid metabolism

Module

M00873

Fatty acid biosynthesis in mitochondria, animals

Reaction

R03383

methylmalonate:CoA ligase (AMP-forming)

R12300

malonate:CoA ligase (AMP-forming)

Disease

H02109

Combined malonic and methylmalonic aciduria

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    K18660  ACSF3; malonyl-CoA/methylmalonyl-CoA synthetase
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    K18660  ACSF3; malonyl-CoA/methylmalonyl-CoA synthetase
Enzymes [BR:ko01000]
6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.76  malonate---CoA ligase
     K18660  ACSF3; malonyl-CoA/methylmalonyl-CoA synthetase

Other DBs

COG:

COG0318

GO:

0090409

Genes

HSA:	197322(ACSF3)

PTR:	454311(ACSF3)

PPS:	100993031(ACSF3)

GGO:	101148664(ACSF3)

PON:	100459097(ACSF3)

NLE:	100584583(ACSF3)

HMH:	116470699(ACSF3)

MCC:	106995123(ACSF3)

MCF:	102124170(ACSF3)

MTHB:

126944311

MNI:	105488855(ACSF3)

CSAB:

103233469(ACSF3)

CATY:

105587971(ACSF3)

PANU:

101011656(ACSF3)

TGE:	112614474(ACSF3)

MLEU:

105533452(ACSF3)

RRO:	104655975(ACSF3)

RBB:	108520197(ACSF3)

TFN:	117088226(ACSF3)

PTEH:

111553831(ACSF3)

CANG:

105501876(ACSF3)

CJC:	100389759(ACSF3)

SBQ:	101045750(ACSF3)

CIMI:

108292820(ACSF3)

CSYR:

103255185(ACSF3)

MMUR:

105855877(ACSF3) 105855961

LCAT:

123625390(ACSF3)

PCOQ:

105820652(ACSF3)

OGA:	100960737(ACSF3)

MMU:	257633(Acsf3)

MCAL:

110299939(Acsf3)

MPAH:

110337582(Acsf3)

RNO:	498962(Acsf3)

MCOC:

116070344(Acsf3)

ANU:	117723499(Acsf3)

MUN:	110545227(Acsf3)

CGE:	100764604(Acsf3)

MAUA:

101825930(Acsf3)

PROB:

127234431(Acsf3)

PLEU:

114700982(Acsf3)

MORG:

121446712(Acsf3)

MFOT:

126515517

AAMP:

119802155(Acsf3)

NGI:	103739998(Acsf3)

HGL:	101708737(Acsf3)

CPOC:

100729577(Acsf3)

CCAN:

109692748(Acsf3)

DORD:

106000388(Acsf3)

DSP:	122127969(Acsf3)

PLOP:

125358078 125358080

NCAR:

124967288

MMMA:

107150817(Acsf3)

OPI:	101534220(ACSF3)

TUP:	102494496(ACSF3)

GVR:	103581547(ACSF3)

CFA:	100683704(ACSF3)

CLUD:

112646830(ACSF3)

VVP:	112924630(ACSF3)

VLG:	121499778(ACSF3)

NPO:	129497179(ACSF3)

AML:	100468387(ACSF3)

UMR:	103673852(ACSF3)

UAH:	113252139(ACSF3)

UAR:	123776597(ACSF3)

ELK:

111152858

LLV:

125088730

MPUF:

101689787(ACSF3)

MNP:	132005584(ACSF3)

MLK:	131817426(ACSF3)

NVS:	122911129(ACSF3)

ORO:	101380436(ACSF3)

EJU:	114201587(ACSF3)

ZCA:	113936602(ACSF3)

MLX:	118023458(ACSF3)

NSU:	110594186(ACSF3)

LWW:

102727809

FCA:	101099921(ACSF3)

PYU:	121009936(ACSF3)

PCOO:

112857522(ACSF3)

PBG:	122494609(ACSF3)

PVIV:

125158758(ACSF3)

LRUF:

124511586

PTG:	102952439(ACSF3)

PPAD:

109245531(ACSF3)

PUC:

125916544

AJU:

106973497

HHV:	120226893(ACSF3)

BTA:	509209(ACSF3)

BOM:	102268238(ACSF3)

BIU:	109572849(ACSF3)

BBUB:

102404462(ACSF3)

BBIS:

104991466(ACSF3)

CHX:	102169989(ACSF3)

OAS:	101109383(ACSF3)

BTAX:

128063428(ACSF3)

ODA:	120872950(ACSF3)

CCAD:

122420910(ACSF3)

MBEZ:

129547165(ACSF3)

SSC:	100739500(ACSF3)

CFR:	102514930(ACSF3)

CBAI:

105080886(ACSF3)

CDK:	105104336(ACSF3)

VPC:	102532795(ACSF3)

BACU:

103006350(ACSF3)

BMUS:

118885830(ACSF3)

LVE:	103069795(ACSF3)

OOR:	101272385(ACSF3)

DLE:	111179387(ACSF3)

PCAD:

102978174(ACSF3)

PSIU:

116744159(ACSF3)

NASI:

112393391(ACSF3)

ECB:	100051639(ACSF3)

EPZ:	103562086(ACSF3)

EAI:	106828244(ACSF3)

MYB:	102264099(ACSF3)

MYD:	102757514(ACSF3)

MMYO:

118674498(ACSF3)

MLF:	102430343(ACSF3)

PKL:	118720679(ACSF3)

EFUS:

103284460(ACSF3)

MNA:	107543506(ACSF3)

DRO:	112300687(ACSF3)

SHON:

118982960(ACSF3)

AJM:	119047029(ACSF3)

PDIC:

114488330(ACSF3)

PHAS:

123806189(ACSF3)

MMF:	118639433(ACSF3)

PPAM:

129083152(ACSF3)

HAI:	109389204(ACSF3)

RFQ:	117035240(ACSF3)

PALE:

102888559(ACSF3)

PGIG:

120622880(ACSF3)

PVP:	105299907(ACSF3)

RAY:	107502352(ACSF3)

MJV:	108398345(ACSF3)

TOD:	119248857(ACSF3)

SARA:

101537950(ACSF3)

SETR:

126027295(ACSF3)

LAV:	100665435(ACSF3)

TMU:

101348352

ETF:	101655659(ACSF3)

MDO:	100026661(ACSF3)

GAS:	123236764(ACSF3)

SHR:	100934834(ACSF3)

AFZ:

127547781

PCW:	110210298(ACSF3)

OAA:	100080846(ACSF3)

GGA:	427561(ACSF3)

PCOC:

116244002(ACSF3)

MGP:	104913064(ACSF3)

CJO:	107319518(ACSF3)

TPAI:

128081983(ACSF3)

LMUT:

125699342(ACSF3)

NMEL:

110404322(ACSF3)

APLA:

101789434(ACSF3)

ACYG:

106046510(ACSF3)

CATA:

118257886(ACSF3)

AFUL:

116493804(ACSF3)

TGU:	100226659(ACSF3)

LSR:	110468775(ACSF3)

SCAN:

103816762(ACSF3)

PMOA:

120496217(ACSF3)

OTC:	121333781(ACSF3)

PRUF:

121362548(ACSF3)

GFR:	102043804(ACSF3)

FAB:	101810484(ACSF3)

OMA:	130257928(ACSF3)

PHI:	102101860(ACSF3)

PMAJ:

107209950(ACSF3)

CCAE:

111934399(ACSF3)

CCW:	104691853(ACSF3)

CBRC:

103620532(ACSF3)

ETL:	114068202(ACSF3)

ZAB:	102065548(ACSF3)

ACHL:

103809977(ACSF3)

SVG:	106852095(ACSF3)

MMEA:

130585892(ACSF3)

HRT:	120757801(ACSF3)

FPG:	101914803(ACSF3)

FCH:	102048057(ACSF3)

CLV:	102096424(ACSF3)

EGZ:	104127039(ACSF3)

NNI:	104023568(ACSF3)

PCRI:

104028169(ACSF3)

PLET:

104617625(ACSF3)

EHS:	104509138(ACSF3)

PCAO:

104052872(ACSF3)

ACUN:

113484628(ACSF3)

TALA:

104357120(ACSF3)

PADL:

103913407(ACSF3)

AFOR:

103893828(ACSF3)

ACHC:

115345347(ACSF3)

HALD:

104315199

HLE:	104839335(ACSF3)

AGEN:

126041139

GCL:

127021279

CCRI:

104163865(ACSF3)

CSTI:

104550171(ACSF3)

CMAC:

104476845(ACSF3)

MUI:	104541380(ACSF3)

BREG:

104634610(ACSF3)

FGA:	104081181(ACSF3)

GSTE:

104259801(ACSF3)

MNB:

103782423

OHA:	104337077(ACSF3)

NNT:	104403733(ACSF3)

SHAB:

115619563(ACSF3)

DPUB:

104303774(ACSF3)

PGUU:

104462159(ACSF3)

ACAR:

104530325

CPEA:

104398325(ACSF3)

AVIT:

104278681(ACSF3)

CVF:	104290390(ACSF3)

RTD:	128908294(ACSF3)

CUCA:

104061254(ACSF3)

TEO:	104374267(ACSF3)

BRHI:

104497493

AAM:	106489294(ACSF3)

AROW:

112978488(ACSF3)

NPD:	112949843(ACSF3)

TGT:	104580329(ACSF3)

DNE:	112989078(ACSF3)

SCAM:

104145363(ACSF3)

ASN:	102375874(ACSF3)

AMJ:	102560749(ACSF3)

CPOO:

109310717(ACSF3)

GGN:	109289385(ACSF3)

PSS:	102445720(ACSF3)

CMY:	102929679(ACSF3)

CCAY:

125620591(ACSF3)

DCC:	119841215(ACSF3)

CPIC:

101938726(ACSF3)

TST:	117886499(ACSF3)

CABI:

116815661(ACSF3)

MRV:	120384448(ACSF3)

ACS:	100568268(acsf3)

ASAO:

132783286(ACSF3)

PVT:	110076304(ACSF3)

SUND:

121914550(ACSF3)

PBI:	103058003(ACSF3)

PMUR:

107283518(ACSF3)

CTIG:

120302479(ACSF3)

APRI:

131184120(ACSF3)

PTEX:

113448911(ACSF3)

NSS:	113427288(ACSF3)

VKO:	123022232(ACSF3)

PMUA:

114602140(ACSF3)

ZVI:	118086900(ACSF3)

HCG:	128334561(ACSF3)

GJA:	107106555(ACSF3)

STOW:

125443206(ACSF3)

EMC:	129343797(ACSF3)

XLA:	444743(acsf3.S)

XTR:	100158470(acsf3)

NPR:	108787714(ACSF3)

RTEM:

120917967(ACSF3)

BBUF:

120980761(ACSF3)

BGAR:

122920838(ACSF3)

MUO:	115459023 115470954(ACSF3)

GSH:	117358682(ACSF3)

DRE:	562292(acsf3)

SRX:	107730180(acsf3)

SANH:

107663040

SGH:

107561460

CCAR:

109099865

CAUA:

113106348(acsf3)

CGIB:

127962506

PTET:

122349542(acsf3)

LROH:

127168923(acsf3)

OMC:	131544946(acsf3)

PPRM:

120492711(acsf3)

MAMB:

125265845(acsf3)

CIDE:

127516458

MASI:

127454111

TROS:

130558876(acsf3)

TDW:	130427980(acsf3)

MANU:

129452571(acsf3)

IPU:

108259686

IFU:	128602802(acsf3)

PHYP:

113546722

SMEO:

124380225(acsf3)

TFD:	113649677(acsf3)

TVC:	132838562(acsf3)

AMEX:

103034152(acsf3)

CMAO:

118817602(acsf3)

EEE:	113575703(acsf3)

CHAR:

105892910(acsf3)

TRU:	101063367(acsf3)

TFS:	130521828(acsf3)

TNG:	GSTEN00017876G001

LCO:	104922786(acsf3)

NCC:	104951573(acsf3)

TBEN:

117471183(acsf3)

CGOB:

115006343(acsf3)

PGEO:

117444164(acsf3)

GACU:

117546593(acsf3)

EMAC:

134862521(acsf3)

ELY:	117259984(acsf3)

EFO:	125904216(acsf3)

PLEP:

121949618(acsf3)

SLUC:

116067765(acsf3)

ECRA:

117950759(acsf3)

ESP:	116690330(acsf3)

PFLV:

114561012(acsf3)

GAT:	120810785(acsf3)

PPUG:

119196609(acsf3)

AFB:	129104239(acsf3)

CLUM:

117728665(acsf3)

PSWI:

130192161(acsf3)

MSAM:

119889931(acsf3)

SCHU:

122880593(acsf3)

CUD:	121510882(acsf3)

ALAT:

119018431(acsf3)

MZE:	101468267(acsf3)

ONL:	100707810(acsf3)

OAU:	116324283(acsf3)

OLA:	101170745(acsf3)

OML:	112161017(acsf3)

CSAI:

133461187(acsf3)

XMA:	102230562(acsf3)

XCO:	114143356(acsf3)

XHE:	116718898(acsf3)

PRET:

103462378(acsf3)

PFOR:

103139337(acsf3)

PLAI:

106946109(acsf3)

PMEI:

106928014(acsf3)

GAF:	122822434(acsf3)

PPRL:

129369656(acsf3)

CVG:	107091333(acsf3)

CTUL:

119782778(acsf3)

GMU:	124867547(acsf3)

NFU:	107381230(acsf3)

KMR:	108250104(acsf3)

ALIM:

106513917(acsf3)

NWH:	119428685(acsf3)

AOCE:

111588400(acsf3)

MCEP:

125005483(acsf3)

CSEM:

103378655(acsf3)

POV:	109624726(acsf3)

SSEN:

122772676(acsf3)

HHIP:

117757849(acsf3)

HSP:	118112817(acsf3)

SMAU:

118302339(acsf3)

LCF:

108887665

SDU:	111238435(acsf3)

SLAL:

111668336(acsf3)

XGL:	120795235(acsf3)

HCQ:	109519728(acsf3)

SSCV:

125967316

SBIA:

133498296(acsf3)

PEE:	133415828(acsf3)

PTAO:

133472753(acsf3)

BPEC:

110173014(acsf3)

MALB:

109965423(acsf3)

BSPL:

114851768(acsf3)

SJO:	128357204(acsf3)

SASA:

106562165(acsf3)

STRU:

115202980(acsf3)

OTW:	112249120 112263579(acsf3)

OMY:	110506418(acsf3) 110526303

OGO:	124033831 124035813

ONE:	115113588(acsf3)

OKI:

OKE:

SALP:

SNH:

CCLU:

121559458(acsf3)

ELS:	105017127(acsf3)

SFM:	108934574(acsf3)

PKI:	111832951(acsf3)

AANG:

118215780(acsf3)

LOC:	102693053(acsf3)

PSPA:

121326066(acsf3)

ARUT:

117425030

PSEX:

120535435(acsf3)

LCM:	102359073(ACSF3)

CMK:	103188085(acsf3)

RTP:

109922101

CPLA:

122558181(acsf3)

HOC:	132823618(acsf3)

LERI:

129715058(acsf3)

PMRN:

116956060

LRJ:	133357913 133358034

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

AJC:

SKO:	102806707 102808696

DME:	Dmel_CG18155(Acsf3)

DER:

6551437

DSE:

6618977

DSI:	Dsimw501_GD16841(Dsim_GD16841)

DYA:	Dyak_GE15712

DAN:

6503827

DSR:

110183531

DPO:	6901754 6903086

DPE:	6588871 6589366 6597648

DMN:	108163390 108163922 108164940

DWI:

6637694

DGR:

6565671

DMO:	Dmoj_GI15946

DAZ:

DNV:

DHE:

DVI:

CCAT:

AOQ:	129244418 129245156

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

CLON:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ000791 CpipJ_CPIJ006459

CPII:

CNS:

BCOO:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:	109542551 109545632

SOY:	115878322 115878746

AGRG:

126735847 126740154

ATD:

109595780

CSET:

123307725

AGB:	108903910 108917560

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

MSEX:

DPL:	KGM_203551 KGM_203552 KGM_203553

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:	105384618 105384619

PGW:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

CLEC:

HHAL:

NLU:

HVI:

MQU:	128994034 128995871

PHU:	Phum_PHUM550040

FOC:	113202116 113204159

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_304782 DAPPUDRAFT_304783

DMK:	116917241 116917243

DPZ:	124329057 124329064

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:	111708016 111708041 111708064

LSM:	121114532 121117950

TCF:	131879262 131883797

PPOI:

119089971

DSV:	119431398 119464687

RSAN:

119375532 119378299

RMP:	119176316 119176350

VDE:	111252504 111252612

VJA:	111264832 111267693

CSCU:

111623736 111626442 111626458

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

HRO:	HELRODRAFT_112159

LGI:	LOTGIDRAFT_179813

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

OBI:

OSN:

LAK:

NVE:

EPA:

ATEN:

AMIL:

PDAM:

SPIS:

HSY:

AQU:	100638565 105315690

ATH:	AT3G16170(AAE13)

ALY:

9321193

CRB:

17893307

CSAT:

104745942 104765454 104781031

EUS:	EUTSA_v10020466mg

BRP:	103840132 103869849

BNA:	106348567 106376853 106397262 106452226 125596288

BOE:	106316369 106343566

RSZ:	108813652 108856547

THJ:

104817978

CPAP:

110824700 110825920

CIT:

102619243

CIC:	CICLE_v10025185mg

PVY:

MINC:

TCC:

GRA:

GHI:	107897183 107913899

GAB:

HSYR:

DZI:

EGR:

GMX:	100810130 100813324

GSJ:	114418008 114422397

PVU:	PHAVU_010G148300g

VRA:

VAR:

VUN:

VUM:

CCAJ:

APRC:

MTR:	25491371 25491411

TPRA:

123921590 123921922

CAM:	101497000 101510623

PSAT:

127107645 127107646

VVO:	131601197 131601200 131601236

LJA:	Lj3g3v2312070.1(Lj3g3v2312070.1)

ADU:

107464053

AIP:

107618487

AHF:	112709904 112778582

LANG:

109347001 109347831

PCIN:

129288809

QSA:	O6P43_018174

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103405442 103421837

MSYL:

PXB:

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:

MESC:

POP:

PEU:

PALZ:

JRE:

CILL:

CAVE:

QSU:	111988084 111994248 112019048

QLO:

115991708

TWL:	119990383 120011548

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:	132603690 132633380

NTA:	107769691 107773712 107785193 107789300 107800203 107812885

NSY:	104234782 104246019

NTO:	104090327 104118498

NAU:	109206524 109225548 109238134

INI:	109188086 109192466

ITR:	115997392 116010460

SIND:

OEU:

EGT:

SSPL:

SMIL:

SHIS:

APAN:

HAN:

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:

AEW:	130750026 130775420

BVG:

104904717

SOE:

110801728

CQI:	110698807 110703394

ATRI:

MOF:

NNU:

MING:

TSS:

PSOM:

OSA:

DOSA:

Os01t0761300-01(Os01g0761300)

OBR:

OGL:

BDI:

ATS:

TDC:	119269071 119277064

TAES:

123062128 123070852 123079242

TUA:	125528198 125544837

LPER:

LRD:

SBI:

ZMA:

SITA:

SVS:

PVIR:

PHAI:

PDA:	103706846 103709486

EGU:	105044446 105047362

MUS:

103975964

ZOF:	121978800 122012155 122015109 122037780

DCT:

PEQ:

AOF:

MSIN:

NCOL:

ATR:	18426654 18426668

SMO:	SELMODRAFT_131422 SELMODRAFT_177598

PPP:	112284600 112296160

VCN:	VOLCADRAFT_104041

MNG:

MNEG_8922

CSL:	COCSUDRAFT_1836

CVR:	CHLNCDRAFT_133799 CHLNCDRAFT_29462

APRO:

F751_6027

OLU:	OSTLU_12975

OTA:	OT_ostta10g01690

BPG:	Bathy11g01650

MIS:	MICPUN_59981 MICPUN_98438

MPP:	MICPUCDRAFT_24314(JGI:MicpuC2_24314) MICPUCDRAFT_52797(JGI:MicpuC2_52797)

GSL:	Gasu_34930

CCP:	CHC_T00008472001

SLB:	AWJ20_24(PCS60)

NCR:

NCU02107

NTE:	NEUTE1DRAFT70536(NEUTE1DRAFT_70536)

SMP:	SMAC_05001

PAN:	PODANSg09513

PBEL:

PPSD:

PPSP:

PPSA:

TTT:	THITE_2121359

MTM:	MYCTH_2294540

CTHR:

MGR:

PPEI:

PGRI:

SSCK:

FGR:	FGSG_00287 FGSG_02303 FGSG_07659 FGSG_12922

FPU:	FPSE_03824 FPSE_04366 FPSE_07026 FPSE_07971 FPSE_10115

FPOA:

FPOAC1_000298 FPOAC1_008340 FPOAC1_011588

FVN:	FVRRES_00430 FVRRES_12616

FVR:	FVEG_00344 FVEG_12633

FOX:	FOXG_01171 FOXG_07378 FOXG_15314

NHE:	NECHADRAFT_31021

FFC:	NCS54_00163000

FKR:	NCS57_00160200

FMU:	J7337_001618 J7337_003350

TRE:	TRIREDRAFT_106646 TRIREDRAFT_4069 TRIREDRAFT_54667

TRR:	M419DRAFT_32232 M419DRAFT_34488 M419DRAFT_88629

MAW:	MAC_00212 MAC_05407 MAC_05529

MAJ:	MAA_04958 MAA_05179 MAA_09853

PCHM:

VFPPC_06377 VFPPC_07586 VFPPC_08905

CMT:	CCM_07604 CCM_07930

AMUS:

LMH87_006764

PLJ:	VFPFJ_09993

PTKZ:

JDV02_009056

VAL:	VDBG_03870

VDA:	VDAG_01098

CFJ:	CFIO01_01577

CLUP:

CLUP02_13754

CHIG:

CH63R_05847

SAPO:

SAPIO_CDS5532

ELA:	UCREL1_8444

PFY:	PFICI_06234

SSL:	SS1G_04708

BFU:	BCIN_01g08480

MBE:	MBM_08760 MBM_09235

PSCO:

LY89DRAFT_683638

GLZ:	GLAREA_11904

NFI:	NFIA_044280

AOR:	AO090023000549

AFV:	AFLA_006721 AFLA_006894

APUU:

APUU_61032S APUU_71250S

PCS:	N7525_002592

POU:	POX_c03552 POX_f08211

TRG:	TRUGW13939_05835 TRUGW13939_05837

CIM:	CIMG_05890 CIMG_08112

CPW:	CPC735_021270 CPC735_025000

URE:	UREG_02383 UREG_03795

PBL:	PAAG_08948

PBN:	PADG_08572

ABE:	ARB_00727 ARB_06354 ARB_07764

TVE:	TRV_00180 TRV_02925 TRV_07433

PNO:	SNOG_00119

PTE:

PTT_18085

BZE:	COCCADRAFT_10116 COCCADRAFT_107739 COCCADRAFT_34691

BSC:	COCSADRAFT_25491 COCSADRAFT_343027

BOR:	COCMIDRAFT_4043 COCMIDRAFT_7641

AALT:

CC77DRAFT_1004645 CC77DRAFT_1015556 CC77DRAFT_1066775

ARAB:

EKO05_0004052

ZTR:	MYCGRDRAFT_70699 MYCGRDRAFT_85953

PFJ:	MYCFIDRAFT_25183 MYCFIDRAFT_60682

FFU:	CLAFUR5_08572

CBET:

CB0940_01520

BCOM:

BAUCODRAFT_578721 BAUCODRAFT_73329

NPA:	UCRNP2_5058

CNE:

CNC03230

CNB:

CNBC3980

CNG:	CNAG_01836

CCAC:

CcaHIS019_0400220(CcaverHIS019_0400220)

MBR:	MONBRDRAFT_26383

SRE:	PTSG_11334

DDI:	DDB_G0289539

DPP:	DICPUDRAFT_93333

DFA:

DFA_09639

SMIN:

v1.2.017530.t1(symbB.v1.2.017530.t1) v1.2.017530.t2(symbB.v1.2.017530.t2) v1.2.017530.t3(symbB.v1.2.017530.t3)

PIF:	PITG_15496

PSOJ:

PHYSODRAFT_555724

SPAR:

SPRG_09682 SPRG_09691

NGR:	NAEGRDRAFT_38119

PAQM:

E0F26_07155

EEI:	NX720_07100

EMP:	EZMO1_0766

SFU:

Sfum_0297

DMP:

FAK_02380

SCL:	sce7641(fadD4)

SCU:	SCE1572_44155

PAUU:

E8A73_014455

MRM:	A7982_08586

LLU:	AKJ09_07510

EUZ:	DVS28_a4677

SYNP:

Syn7502_02781

WNA:	KA717_19980

CMP:	Cha6605_1276

CYN:	Cyan7425_1330

CAN:	Cyan10605_3248

CYP:	PCC8801_2136

CYH:	Cyan8802_2184

GVI:

glr1122

GML:	ISF26_17365

NPU:	Npun_R4594

NOS:	Nos7107_4348

NFL:	COO91_03131

NED:	HUN01_19095

AWA:	AA650_14050

TOQ:	HCG51_04250

PPHT:

GA004_17065

MTAR:

DF168_01213(lcfB)

LCRE:

Pla8534_16800(lcfB_3)

HHY:	Halhy_5401

SGN:

SGRA_2823

AUP:	AsAng_0024590

ALM:	AO498_11530

ALGO:

SLI:

SPIR:

SPIK:

SFOL:

PSEZ:

AANH:

ALEN:

EOL:	Emtol_0619

RSI:	Runsl_2171

RUN:	DR864_19545

RUP:	DTQ70_10620

FPF:	DCC35_19060

IRO:	RT717_23180

RBI:	RB2501_09090

MART:

MARB:

MLIO:

Reference

PMID:21841779

Authors

Sloan JL, Johnston JJ, Manoli I, Chandler RJ, Krause C, Carrillo-Carrasco N, Chandrasekaran SD, Sysol JR, O'Brien K, Hauser NS, Sapp JC, Dorward HM, Huizing M, Barshop BA, Berry SA, James PM, Champaigne NL, de Lonlay P, Valayannopoulos V, Geschwind MD, Gavrilov DK, Nyhan WL, Biesecker LG, Venditti CP

Title

Exome sequencing identifies ACSF3 as a cause of combined malonic and methylmalonic aciduria.

Journal

Nat Genet 43:883-6 (2011)
DOI:10.1038/ng.908

Sequence

[hsa:197322]

Reference

PMID:21642549

Authors

Chen H, Kim HU, Weng H, Browse J

Title

Malonyl-CoA synthetase, encoded by ACYL ACTIVATING ENZYME13, is essential for growth and development of Arabidopsis.