KEGG ORTHOLOGY: K19348

ORTHOLOGY: K19348

Entry

K19348                      KO

Symbol

TMEM67, MKS3

Name

meckelin

Disease

H00261

Meckel syndrome

H00530

Joubert syndrome and related disorders

H00537

Nephronophthisis

H01001

COACH syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins
    K19348  TMEM67, MKS3; meckelin
Cilium and associated proteins [BR:ko03037]
Primary cilia and associated proteins
  MKS complex
   K19348  TMEM67, MKS3; meckelin

Other DBs

GO:

0031005

Genes

HSA:	91147(TMEM67)

PTR:	472937(TMEM67)

PPS:	100973204(TMEM67)

GGO:	101146893(TMEM67)

PON:	100460277(TMEM67)

NLE:	100597659(TMEM67)

HMH:	116813419(TMEM67)

MCC:	698631(TMEM67)

MCF:	102126597(TMEM67)

MTHB:

126960812

MNI:	105497251(TMEM67)

CSAB:

103237131(TMEM67)

CATY:

105586474(TMEM67)

PANU:

101018110(TMEM67)

TGE:	112630678(TMEM67)

MLEU:

105538740(TMEM67)

RRO:	104658548(TMEM67)

RBB:	108512196(TMEM67)

TFN:	117078995(TMEM67)

PTEH:

111549682(TMEM67)

CANG:

105508217(TMEM67)

CJC:	100413391(TMEM67)

SBQ:	101040622(TMEM67)

CIMI:

108310861(TMEM67)

CSYR:

103266069(TMEM67)

MMUR:

105875676(TMEM67)

LCAT:

123644592(TMEM67)

PCOQ:

105809695(TMEM67)

OGA:	100960637(TMEM67)

MMU:	329795(Tmem67)

MCAL:

110292488(Tmem67)

MPAH:

110338793(Tmem67)

RNO:	313067(Tmem67)

MCOC:

116088065(Tmem67)

ANU:	117698618(Tmem67)

MUN:	110563744(Tmem67)

CGE:	100762830(Tmem67)

MAUA:

101841046(Tmem67)

PROB:

127232137(Tmem67)

PLEU:

114694585(Tmem67)

MORG:

121451580(Tmem67)

MFOT:

126515600

AAMP:

119826792(Tmem67)

NGI:	103745820(Tmem67)

HGL:	101723826(Tmem67)

CPOC:

100719473(Tmem67)

CCAN:

109701899(Tmem67)

DORD:

105982871(Tmem67)

DSP:	122102481(Tmem67)

PLOP:

125360989(Tmem67)

NCAR:

124994076

MMMA:

107142501(Tmem67)

OCU:

100355610

OPI:	101525631(TMEM67)

TUP:	102483993(TMEM67)

GVR:	103593440(TMEM67)

CFA:	487049(TMEM67)

CLUD:

112650714(TMEM67)

VVP:	112931112(TMEM67)

VLG:	121499028(TMEM67)

NPO:	129495788(TMEM67)

AML:	100480482(TMEM67)

UMR:	103661431(TMEM67)

UAH:	113252933(TMEM67)

UAR:	123797883(TMEM67)

ELK:

111146619

LLV:

125098765

MPUF:

101690695(TMEM67)

MNP:	132014162(TMEM67)

MLK:	131826602(TMEM67)

NVS:	122904441(TMEM67)

ORO:	101366639(TMEM67)

EJU:	114214791(TMEM67)

ZCA:	113914565(TMEM67)

MLX:	118015021(TMEM67)

NSU:	110578698(TMEM67)

LWW:	102727549(TMEM67)

FCA:	101089077(TMEM67)

PYU:	121042704(TMEM67)

PCOO:

112859478(TMEM67)

PBG:	122495603(TMEM67)

PVIV:

125156592(TMEM67)

LRUF:

124519053

PTG:	102967594(TMEM67)

PPAD:

109269496(TMEM67)

PUC:

125924547

AJU:

106974893

HHV:	120221637(TMEM67)

BTA:	506762(TMEM67)

BOM:	102282267(TMEM67)

BIU:	109568263(TMEM67)

BBUB:

102415338(TMEM67)

BBIS:

104983954(TMEM67)

CHX:	102188875(TMEM67)

OAS:	101110519(TMEM67)

BTAX:

128059461(TMEM67)

ODA:	120878492(TMEM67)

CCAD:

122451226(TMEM67)

MBEZ:

129560359(TMEM67)

SSC:	100515024(TMEM67)

CFR:	102516066(TMEM67)

CBAI:

105079616(TMEM67)

CDK:	105085732(TMEM67)

VPC:	102539760(TMEM67)

BACU:

103016352(TMEM67)

BMUS:

118883722(TMEM67)

LVE:	103083573(TMEM67)

OOR:	101289572(TMEM67)

DLE:	111180425(TMEM67)

PCAD:

102976217(TMEM67)

PSIU:

116742507(TMEM67)

NASI:

112413482(TMEM67)

ECB:	100051660(TMEM67)

EPZ:	103560683(TMEM67)

EAI:	106831446(TMEM67)

MYB:	102249090(TMEM67)

MYD:	102760344(TMEM67)

MMYO:

118670615(TMEM67)

MLF:	102441386(TMEM67)

PKL:	118718100(TMEM67)

EFUS:

103292346(TMEM67)

MNA:	107534135(TMEM67)

DRO:	112315571(TMEM67)

SHON:

118995560(TMEM67)

AJM:	119038571(TMEM67)

PDIC:

114514737(TMEM67)

PHAS:

123833102(TMEM67)

MMF:	118631691(TMEM67)

PPAM:

129084205(TMEM67)

RFQ:	117033996(TMEM67)

PALE:

102890628(TMEM67)

PGIG:

120614307(TMEM67)

PVP:

105310838

RAY:	107514987(TMEM67)

MJV:	108386626(TMEM67)

TOD:	119239752(TMEM67)

SARA:

101554276(TMEM67)

SETR:

126020461(TMEM67)

LAV:	100666630(TMEM67)

TMU:

101361740

ETF:	101653918(TMEM67)

DNM:	101447663(TMEM67)

MDO:	100029719(TMEM67)

GAS:	123231885(TMEM67) 123253946

SHR:	100925757(TMEM67)

AFZ:

127544284

PCW:	110198549(TMEM67)

OAA:	100079575(TMEM67)

GGA:	420224(TMEM67)

PCOC:

116227608(TMEM67)

MGP:

100543821

CJO:	107310391(TMEM67)

TPAI:

128090769(TMEM67)

LMUT:

125690865(TMEM67)

NMEL:

110393544(TMEM67)

APLA:

101795109(TMEM67)

ACYG:

106030515(TMEM67)

CATA:

118247973(TMEM67)

AFUL:

116485656(TMEM67)

TGU:	100228805(TMEM67)

LSR:	110477469(TMEM67)

SCAN:

103813511(TMEM67)

PMOA:

120500846(TMEM67)

OTC:	121340342(TMEM67)

PRUF:

121352004(TMEM67)

GFR:	102041510(TMEM67)

FAB:	101806740(TMEM67)

OMA:	130249956(TMEM67)

PHI:	102114212(TMEM67)

PMAJ:

107200840(TMEM67)

CCAE:

111924544(TMEM67)

CCW:	104692748(TMEM67)

CBRC:

103613018(TMEM67)

ETL:	114061762(TMEM67)

ZAB:	102060599(TMEM67)

ACHL:

103803536(TMEM67)

SVG:	106860700(TMEM67)

MMEA:

130576016(TMEM67)

HRT:	120760592(TMEM67)

FPG:	101915081(TMEM67)

FCH:	102048335(TMEM67)

CLV:	102097563(TMEM67)

EGZ:	104125850(TMEM67)

NNI:	104016414(TMEM67)

PCRI:

104037985(TMEM67)

PCAO:

104051579(TMEM67)

ACUN:

113476341(TMEM67)

TALA:

104363862(TMEM67)

PADL:

103917303(TMEM67)

AFOR:

103895761(TMEM67)

ACHC:

115340658(TMEM67)

HALD:

104321298(TMEM67)

HLE:	104837760(TMEM67)

AGEN:

126049592

GCL:

127013035

CCRI:

104157308(TMEM67)

CSTI:

104561698(TMEM67)

CMAC:

104481348(TMEM67)

MUI:	104542094(TMEM67)

BREG:

104638875(TMEM67)

LDI:	104346967(TMEM67)

MNB:	103777271(TMEM67)

OHA:	104337562(TMEM67)

NNT:	104403077(TMEM67)

SHAB:

115614447(TMEM67)

DPUB:

104302435(TMEM67)

ACAR:

104531713(TMEM67)

CPEA:

104396576(TMEM67)

AVIT:

104276665(TMEM67)

CVF:	104292459(TMEM67)

RTD:	128906239(TMEM67)

CUCA:

104056747(TMEM67)

TEO:	104373036(TMEM67)

BRHI:

104494680(TMEM67)

AAM:	106483854(TMEM67)

AROW:

112973313(TMEM67)

NPD:	112956526(TMEM67)

TGT:	104578367(TMEM67)

DNE:	112982991(TMEM67)

SCAM:

104144818(TMEM67)

ASN:	102375044(TMEM67) 102379837

AMJ:	102558526 102563102(TMEM67)

CPOO:

109310690 109320400(TMEM67)

GGN:	109289416 109305041(TMEM67)

PSS:	102456982(TMEM67) 102459691

CMY:	102937766(TMEM67) 102944513

CCAY:

125620822 125632663(TMEM67)

DCC:	119851733(TMEM67) 122456337

CPIC:

101941380(TMEM67) 101942456

TST:	117873660(TMEM67)

CABI:

116824655(TMEM67) 116832769

MRV:	120384672 120398248(TMEM67)

ACS:	100559654(tmem67)

ASAO:

132774983(TMEM67)

PVT:	110074783(TMEM67) 110090762

SUND:

121914394 121927928(TMEM67)

PBI:	103048869(TMEM67) 103064665

PMUR:

107292884 107301041

CTIG:

120296698 120310358(TMEM67)

TSR:	106543178(TMEM67)

PGUT:

117668504(TMEM67) 117670995

APRI:

131184273 131195526(TMEM67)

PTEX:

113439911(TMEM67) 113448895

NSS:	113427301 113428344(TMEM67)

VKO:	123020291(TMEM67) 123022385

PMUA:

114600425(TMEM67) 114602156

PRAF:

128417238(TMEM67) 128419402

ZVI:	118087972 118090291(TMEM67)

HCG:	128324380(TMEM67)

GJA:	107109250(TMEM67)

STOW:

125439196(TMEM67) 125443211

EMC:	129333821(TMEM67) 129343817

XLA:	108695384(tmem67.S) 108714094

XTR:	100486474 100492945(tmem67)

NPR:	108790028(TMEM67) 108800428

RTEM:

120917835 120941330(TMEM67)

BBUF:

120980515 121002775(TMEM67)

BGAR:

122924162 122938218(TMEM67)

MUO:	115470927 115478937(TMEM67)

GSH:	117354806(TMEM67) 117358884

DRE:	572194(tmem67)

SRX:	107706069 107723522

SANH:

107657728 107689892(tmem67)

SGH:	107593716 107596064

CCAR:

109111745(tmem67)

CAUA:

113116153(tmem67)

CGIB:

127972289 127974483

PTET:

122359873(tmem67)

LROH:

127178127(tmem67)

OMC:	131522409(tmem67)

PPRM:

120484613 120484686(tmem67)

RKG:	130084227(tmem67)

MAMB:

125242965(tmem67)

CIDE:

127497589

MASI:

127454442

TROS:

130557888(tmem67)

TDW:	130433331(tmem67)

MANU:

129448271(tmem67)

IPU:

108256397

IFU:	128600030(tmem67)

PHYP:

113532884(tmem67)

SMEO:

124403710(tmem67)

TFD:	113659232(tmem67)

TVC:	132840181(tmem67)

AMEX:

103025602(tmem67)

CMAO:

118799035(tmem67)

EEE:	113567950 113577910(tmem67)

CHAR:

105893954(tmem67) 116219437

TRU:	101070430(tmem67)

TFS:	130533206(tmem67)

TNG:	GSTEN00034026G001

LCO:	104923069(tmem67)

NCC:

104952976

TBEN:

117480734(tmem67)

CGOB:

115021271(tmem67)

PGEO:

117461035(tmem67)

GACU:

117553997(tmem67)

EMAC:

134861925(tmem67)

ELY:	117265457(tmem67)

EFO:	125893658(tmem67)

PLEP:

121945802(tmem67)

SLUC:

116049485(tmem67)

ECRA:

117946403(tmem67)

ESP:	116691616(tmem67)

PFLV:

114557115(tmem67)

GAT:	120810889(tmem67)

PPUG:

119197781(tmem67)

AFB:	129109485(tmem67)

CLUM:

117745299(tmem67)

PSWI:

130187904(tmem67)

MSAM:

119897664(tmem67)

SCHU:

122881897(tmem67)

CUD:	121513688(tmem67)

ALAT:

119005601(tmem67)

MZE:	101467949(tmem67)

ONL:	100693978(tmem67)

OAU:	116331333(tmem67)

OLA:	101168892(tmem67)

OML:	112144012(tmem67)

CSAI:

133431117(tmem67)

XMA:	102226173(tmem67)

XCO:	114141642(tmem67)

XHE:	116717665(tmem67)

PRET:

103478658(tmem67)

PFOR:

103140863(tmem67)

PLAI:

106945856(tmem67)

PMEI:

106929899(tmem67)

GAF:	122831603(tmem67)

PPRL:

129371168(tmem67)

CVG:	107081578(tmem67)

CTUL:

119787253(tmem67)

GMU:	124865471(tmem67)

NFU:	107379722(tmem67)

KMR:	108241048(tmem67)

ALIM:

106515105(tmem67)

NWH:	119409417(tmem67)

AOCE:

111587048 111588677(tmem67)

MCEP:

125022883(tmem67)

CSEM:

103388150(tmem67)

POV:	109633119(tmem67)

SSEN:

122764066(tmem67)

HHIP:

117777242(tmem67)

HSP:	118113142(tmem67)

SMAU:

118312834(tmem67)

LCF:

108889615

SDU:	111236930(tmem67)

SLAL:

111650827(tmem67)

XGL:	120783620(tmem67)

HCQ:	109528994 109529000

SSCV:

125975349 125975395

SBIA:

133501212 133501213

PEE:	133401818 133401819

PTAO:

133479886(tmem67) 133480192

BPEC:

110171526(tmem67)

MALB:

109964076(tmem67)

BSPL:

114842512(tmem67)

SJO:	128366111(tmem67)

SASA:

106605944(tmem67) 106606053

STRU:

115180980 115180984

OTW:	112222686 121841013

OMY:	110534143 110535612(tmem67)

OGO:	123998303 124017051(tmem67)

ONE:	115124318(tmem67)

OKI:	109885130 109886994

OKE:	118376520 118376524

SALP:

112072879

SNH:	120030986 120036436

CCLU:

121542330 121543892

ELS:	105018914(tmem67)

SFM:	108940668(tmem67)

PKI:	111844201(tmem67)

AANG:

118214833 118226265(tmem67)

LOC:	102685420 102698359(tmem67)

PSPA:

121313206 121314981 121325460

ARUT:

117399686(tmem67) 117425336

PSEX:

120515927(tmem67) 120535491

LCM:	102363435(TMEM67)

CMK:	103175920 103184606(tmem67)

CPLA:

122548997(tmem67) 122558236

HOC:	132815227(tmem67) 132823874

LERI:

129696003 129705337

PMRN:

116944106(TMEM67)

LRJ:	133350817(TMEM67)

BFO:

BBEL:

CIN:

SCLV:

SPU:

APLC:

SKO:	100373519(TMEM67)

DME:	Dmel_CG15923(CG15923)

DER:

6553601

DSE:

6619241

DSI:	Dsimw501_GD20049(Dsim_GD20049)

DYA:	Dyak_GE25054

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI22171

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:

MDE:

SCAC:

LSQ:

GFS:

ECOE:

CLON:

AGA:

ACOZ:

AARA:

AMER:

121589148 121589156 121601855

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ003554

CPII:

CNS:

BCOO:

AME:

ALAB:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

CCAL:

OBB:

OLG:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CCIN:

MSEX:

DPL:	KGM_214370

VCD:

MCIX:

PPOT:

PRAP:

ZCE:

HAW:

TNL:

SLIU:

OFU:

PGW:

CCRN:

API:	100166451 100571596

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

CLEC:

NLU:

MQU:	128997575 129005206

PHU:	Phum_PHUM405200

FOC:

TPAL:

ZNE:

CSEC:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_330591

DMK:

DPZ:

PVM:

PJA:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

TCF:	131881070 131881178

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

CEL:	CELE_F35D2.4(mks-3)

CBR:	CBG_13002(Cbr-mks-3)

CRQ:	GCK72_006554

TSP:

Tsp_12049

HRO:	HELRODRAFT_70743

LGI:	LOTGIDRAFT_192673

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MMER:

RPHI:

DPOL:

OBI:

OSN:

LAK:	106160567 106160568 106177748

SMM:	Smp_156860

SHX:	MS3_00009092(TMEM67)

NVE:

5507710

EPA:

110235075

ATEN:

116299407

ADF:	107343040 107353397 107353417

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

TAD:	TRIADDRAFT_55538

AQU:

105314233

CRE:	CHLRE_13g584901v5

VCN:	VOLCADRAFT_116951

MNG:	MNEG_15080

MIS:	MICPUN_100443

MPP:	MICPUCDRAFT_46834(JGI:MicpuC2_46834)

MBR:	MONBRDRAFT_38408

SRE:	PTSG_00613

TET:	TTHERM_01016240 TTHERM_01205280

PTM:	GSPATT00005677001 GSPATT00015939001

TPS:	THAPSDRAFT_1783

AAF:	AURANDRAFT_61468

PIF:	PITG_05608

PSOJ:

PHYSODRAFT_480509

SPAR:

SPRG_07532

GTT:	GUITHDRAFT_162956

TBR:	Tb927.5.3540

TCR:	511649.110

LMA:	LMJF_27_0020

LIF:	LINJ_27_0020

LDO:	LDBPK_270020

LMI:	LMXM_27_0020

NGR:	NAEGRDRAFT_62841

TVA:	TVAG_2v0231840 TVAG_2v0242650 TVAG_2v0392570 TVAG_2v0480890 TVAG_2v0535040 TVAG_2v0556230

» show all

Reference

PMID:19515853

Authors

Tammachote R, Hommerding CJ, Sinders RM, Miller CA, Czarnecki PG, Leightner AC, Salisbury JL, Ward CJ, Torres VE, Gattone VH 2nd, Harris PC

Title

Ciliary and centrosomal defects associated with mutation and depletion of the Meckel syndrome genes MKS1 and MKS3.

Journal

Hum Mol Genet 18:3311-23 (2009)
DOI:10.1093/hmg/ddp272

Sequence

[hsa:91147]

LinkDB

DBGET integrated database retrieval system