KEGG   ORTHOLOGY: K19647
Entry
K19647                      KO                                     
Symbol
hgd
Name
2-hydroxymethylglutarate dehydrogenase [EC:1.1.1.291]
Pathway
map00760  Nicotinate and nicotinamide metabolism
map01120  Microbial metabolism in diverse environments
Reaction
R07985  (S)-2-hydroxymethylglutarate:NAD+ oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    K19647  hgd; 2-hydroxymethylglutarate dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.291  2-hydroxymethylglutarate dehydrogenase
     K19647  hgd; 2-hydroxymethylglutarate dehydrogenase
Other DBs
COG: COG2084
GO: 0043718
Genes
PPAV: LOZ86_04730
ADY: HLG70_00410
CTEZ: CT3_33160
ACUT: MRB58_12300
SNAP: PQ455_08180
STEL: STAQ_18560(mmsB)
SHUA: PQ477_20810
FEC: QNH15_18225
ALKL: MM271_17440
HYI: K2M58_02455
EFF: skT53_09660(mmsB) skT53_13840(garR_1)
CPAT: CLPA_c02850(hgd)
CPAE: CPAST_c02850(hgd)
ACOL: K5I23_11310
DOR: Desor_0451
TFR: BR63_08425
ACAE: HYG86_14495
PROM: QO263_18055
GEK: kuro4_03320(mmsB) kuro4_15860(garR) kuro4_16270
TEP: TepRe1_0398
TAE: TepiRe1_0442(Hgd)
NTH: Nther_2161
STED: SPTER_39160(hgd)
KBB: ccbrp13_22740 ccbrp13_64320
IPO: Ilyop_0116
NAY: HYG81_23765
AG: ABC88394(hgd)
 » show all
Reference
PMID:16894175
  Authors
Alhapel A, Darley DJ, Wagener N, Eckel E, Elsner N, Pierik AJ.
  Title
Molecular and functional analysis of nicotinate catabolism in Eubacterium barkeri.
  Journal
Proc Natl Acad Sci U S A 103:12341-6 (2006)
DOI:10.1073/pnas.0601635103
  Sequence
[ag:ABC88394]
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