KEGG   ORTHOLOGY: K22498
Entry
K22498            Tight     KO                                     
Symbol
NS4B
Name
Hepatitis C virus non-structural protein 4B
Pathway
map03230  Viral genome structure
map03240  Viral replication
map05160  Hepatitis C
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03230 Viral genome structure
    K22498  NS4B; Hepatitis C virus non-structural protein 4B
   03240 Viral replication
    K22498  NS4B; Hepatitis C virus non-structural protein 4B
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    K22498  NS4B; Hepatitis C virus non-structural protein 4B
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K22498  NS4B; Hepatitis C virus non-structural protein 4B
Viral proteins [BR:ko03200]
 +ssRNA viruses
  Hepatitis C virus (Hepacivirus C)
   K22498  NS4B; Hepatitis C virus non-structural protein 4B
Genes
VP: 951475-8(NS4B)
Reference
PMID:27315218
  Authors
Hu B, Li S, Zhang Z, Xie S, Hu Y, Huang X, Zheng Y
  Title
HCV NS4B targets Scribble for proteasome-mediated degradation to facilitate cell transformation.
  Journal
Tumour Biol 37:12387-12396 (2016)
DOI:10.1007/s13277-016-5100-4
  Sequence
[vp:951475-8]
Reference
PMID:23836234
  Authors
Scheel TK, Rice CM
  Title
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies.
  Journal
Nat Med 19:837-49 (2013)
DOI:10.1038/nm.3248
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