KEGG   ORTHOLOGY: K22891
Entry
K22891                      KO                                     
Symbol
nef
Name
HIV protein Nef
Pathway
map03230  Viral genome structure
map03250  Viral life cycle - HIV-1
map03260  Virion - Human immunodeficiency virus
map05170  Human immunodeficiency virus 1 infection
Network
nt06161  Human immunodeficiency virus 1 (HIV-1)
nt06516  TNF signaling
nt06517  TLR signaling
nt06524  Apoptosis
  Element
N00439  HIV Nef to TLR2/4-MAPK signaling pathway
N00442  HIV Nef to TNF-NFKB signaling pathway
N00443  HIV Vpr/Nef/Tat to TNF-NFKB signaling pathway
N00445  HIV Tat/Nef to TNF-p38 signaling pathway
N00448  HIV Tat/Nef to crosstalk between extrinsic and intrinsic apoptotic pathways
N00449  HIV Tat/Nef to crosstalk between extrinsic and intrinsic apoptotic pathways
N00452  HIV Nef to intrinsic apoptotic pathway
N00461  HIV Nef to antigen processing and presentation by MHC class I molecules
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03230 Viral genome structure
    K22891  nef; HIV protein Nef
   03250 Viral life cycle - HIV-1
    K22891  nef; HIV protein Nef
   03260 Virion - Human immunodeficiency virus
    K22891  nef; HIV protein Nef
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K22891  nef; HIV protein Nef
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K22891  nef; HIV protein Nef
Viral proteins [BR:ko03200]
 ssRNA-RT viruses
  Human immunodeficiency virus
   K22891  nef; HIV protein Nef
Genes
VG: 1490008(nef) 156110(nef) 1724715(HIV2gp8) 956109(nef)
Reference
PMID:27161574
  Authors
Pereira EA, daSilva LL
  Title
HIV-1 Nef: Taking Control of Protein Trafficking.
  Journal
Traffic 17:976-96 (2016)
DOI:10.1111/tra.12412
  Sequence
[vg:156110]
LinkDB

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