KEGG ORTHOLOGY: K23080

ORTHOLOGY: K23080

Entry

K23080                      KO

Symbol

CASTOR1

Name

cytosolic arginine sensor for mTORC1 subunit 1

Pathway

map04150

mTOR signaling pathway

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    K23080  CASTOR1; cytosolic arginine sensor for mTORC1 subunit 1

Other DBs

GO:

0034618

Genes

HSA:	652968(CASTOR1)

PTR:	100612523(CASTOR1)

PPS:	103785036(CASTOR1)

GGO:	101138845(CASTOR1)

PON:	100172893(CASTOR1)

NLE:	100604169(CASTOR1)

HMH:	116458789(CASTOR1)

MCC:	107000642(CASTOR1)

MCF:	102126082(CASTOR1)

MTHB:

126963943

MNI:	105487241(CASTOR1)

CSAB:

103223159(GATSL3)

CATY:

105575715(GATSL3)

PANU:

103888302(CASTOR1)

TGE:	112632945(CASTOR1)

MLEU:

105538990(GATSL3)

RRO:	104659505(CASTOR1)

RBB:	108517584(GATSL3)

TFN:	117096179(CASTOR1)

PTEH:

111525347(CASTOR1)

CANG:

105522993(GATSL3)

CJC:	103796530(CASTOR1)

SBQ:	104652943(GATSL3)

CIMI:

108283327(CASTOR1) 108317003

CSYR:

103258507(CASTOR1)

MMUR:

105870929(CASTOR1)

LCAT:

123625830(CASTOR1)

PCOQ:

105821309(GATSL3)

OGA:	100952182(CASTOR1)

MMU:	71962(Castor1)

MCAL:

110305016(Castor1)

MPAH:

110330890(Castor1)

RNO:	360969(Castor1)

MCOC:

116069573(Castor1)

ANU:	117712818(Castor1)

MUN:	110557779(Castor1)

CGE:	100754150(Castor1)

MAUA:

101835408(Castor1)

PROB:

127233697(Castor1)

PLEU:

114694010(Castor1)

MORG:

121436506 121459642

MFOT:

126500810

AAMP:

119806798(Castor1)

NGI:	103740453(Gatsl3)

HGL:	101713428(Gatsl3)

CPOC:

100724420(Castor1)

CCAN:

109697280(Gatsl3)

DORD:

105984363(Gatsl3)

DSP:	122097203(Castor1)

PLOP:

125349277(Castor1)

NCAR:

124991085

MMMA:

107158494(Castor1)

OCU:	100342749(CASTOR1)

OPI:	101521090(CASTOR1)

TUP:	102498873(GATSL3)

GVR:	103589401(GATSL3)

CFA:	609909(CASTOR1)

CLUD:

112676799(CASTOR1)

VVP:	112909829(CASTOR1)

VLG:	121475219(CASTOR1)

NPO:	129507691(CASTOR1)

AML:	100469914(CASTOR1)

UMR:	103681109(CASTOR1)

UAH:	113245030(CASTOR1)

UAR:	123788157(CASTOR1)

ELK:

111160035

LLV:

125082348

MPUF:

101673628(GATSL3)

MNP:	132023323(CASTOR1)

MLK:	131811307(CASTOR1)

NVS:	122903268(CASTOR1)

ORO:	101375275(GATSL3)

EJU:	114225237(CASTOR1)

ZCA:	113913362(CASTOR1)

MLX:	118018645(CASTOR1)

NSU:	110592450(CASTOR1)

LWW:	102749961(CASTOR1)

FCA:	101090554(CASTOR1)

PYU:	121022596(CASTOR1)

PCOO:

112870285(CASTOR1)

PBG:	122470992(CASTOR1)

PVIV:

125149656(CASTOR1)

LRUF:

124518374

PTG:	102968851(GATSL3)

PPAD:

109253581(GATSL3)

PUC:

125914511

AJU:	106983320(CASTOR1)

HHV:	120227360(CASTOR1)

BTA:	506974(CASTOR1)

BOM:	102272136(GATSL3)

BIU:	109571340(GATSL3)

BBUB:

102390046(CASTOR1)

BBIS:

104980228(GATSL3)

CHX:	106501896(GATSL3)

OAS:	101122727(CASTOR1)

BTAX:

128062333(CASTOR1)

ODA:	120862985 120871236(CASTOR1)

CCAD:

122421016(CASTOR1)

MBEZ:

129542739(CASTOR1)

SSC:	100157272(CASTOR1)

CFR:	102520127(CASTOR1)

CBAI:

105066113(GATSL3)

CDK:	105099512(CASTOR1)

VPC:	102542343(CASTOR1)

BACU:

103001973(GATSL3)

BMUS:

118879884(CASTOR1)

LVE:	103087301(GATSL3)

OOR:	101280363(CASTOR1)

DLE:	111162791(CASTOR1)

PCAD:

102978857(CASTOR1)

PSIU:

116765159(CASTOR1)

NASI:

112415115(CASTOR1)

ECB:	100146562(CASTOR1)

EPZ:	103548082(GATSL3)

EAI:	106827170(CASTOR1)

MYB:	102253505(GATSL3)

MYD:	102767487(GATSL3)

MMYO:

118678305(CASTOR1)

MLF:	102421534(CASTOR1)

PKL:	118725378(CASTOR1)

EFUS:

103286856(CASTOR1)

MNA:	107526242(GATSL3)

DRO:	112310857(CASTOR1)

SHON:

118991280(CASTOR1)

AJM:	119055182(CASTOR1)

PDIC:

114509344(CASTOR1)

PHAS:

123810951(CASTOR1)

MMF:	118639964(CASTOR1)

PPAM:

129087466(CASTOR1)

HAI:	109383020(GATSL3)

RFQ:	117017246(CASTOR1)

PALE:

102889700(CASTOR1)

PGIG:

120601896(CASTOR1)

PVP:	105300915 105300951

RAY:	107505417(GATSL3)

MJV:	108396862(CASTOR1)

TOD:	119244837(CASTOR1)

SARA:

101555574(GATSL3)

SETR:

126030616(CASTOR1)

LAV:	100660327(CASTOR1)

TMU:

101359981

ETF:	101638036(CASTOR1)

DNM:	101421128(CASTOR1)

MDO:	100030969(GATSL3)

GAS:	123232432(CASTOR1)

SHR:	100934681(CASTOR1)

AFZ:

127545669

PCW:	110215252(CASTOR1)

OAA:	100087206(CASTOR1)

GGA:	770898(GATSL3)

PCOC:

116228359(CASTOR1)

MGP:	100548680(CASTOR1)

CJO:	107321516(CASTOR1)

TPAI:

128084019(CASTOR1)

LMUT:

125701788(CASTOR1)

NMEL:

110406505(CASTOR1)

APLA:

101796563(CASTOR1)

ACYG:

106049040(CASTOR1)

CATA:

118260815(CASTOR1)

AFUL:

116496246(CASTOR1)

TGU:	100218616(CASTOR1)

LSR:	110474161(CASTOR1)

SCAN:

103818215(CASTOR1)

PMOA:

120510249(CASTOR1)

OTC:	121344411(CASTOR1)

PRUF:

121365079(CASTOR1)

FAB:	101816134(GATSL3)

OMA:	130259780(CASTOR1)

PHI:	102114603(GATSL3)

PMAJ:

107211432(CASTOR1)

CCAE:

111936774(CASTOR1)

CCW:	104695031(CASTOR1)

CBRC:

103623812(GATSL3)

ETL:	114070631(CASTOR1)

ZLE:	135454723(CASTOR1)

ACHL:

103801441(GATSL3)

SVG:	106864822(GATSL3)

MMEA:

130584105(CASTOR1)

HRT:	120760715(CASTOR1)

FPG:	101921957(GATSL3)

FCH:	102054647(CASTOR1)

CLV:	102084838(CASTOR1)

EGZ:	104129936(GATSL3)

NNI:	104010592(GATSL3)

PCRI:

104034063

ACUN:

113486177(CASTOR1)

TALA:

116962349(CASTOR1)

AFOR:

103896509(GATSL3)

ACHC:

115346221(CASTOR1)

HLE:	104829245(GATSL3)

AGEN:

126040203

GCL:

127022855

MUI:	104542319(GATSL3)

LDI:

104340325

SHAB:

115614849(CASTOR1)

DPUB:

104309022(GATSL3)

ACAR:

104525916(CASTOR1)

CPEA:

104388420(GATSL3)

RTD:	128917283(CASTOR1)

CUCA:

104056144(GATSL3)

AAM:	106494516(GATSL3)

AROW:

112971307(CASTOR1)

NPD:	112947974(CASTOR1)

TGT:	104571001(GATSL3)

DNE:	112987984(CASTOR1)

ASN:	102377620(CASTOR1)

AMJ:	102565452(GATSL3)

CPOO:

109312919(GATSL3)

GGN:	109290307(GATSL3)

CMY:	102937906(CASTOR1)

CCAY:

125622829(CASTOR1)

DCC:	119843871(CASTOR1)

CPIC:

101938308(CASTOR1)

TST:	117888014(CASTOR1)

CABI:

116821248(CASTOR1)

MRV:	120386287(CASTOR1)

PVT:	110069937(CASTOR1)

SUND:

121936258(CASTOR1)

PBI:	103052393(CASTOR1)

PMUR:

107288791(CASTOR1)

CTIG:

120303248(CASTOR1)

TSR:	106555340(GATSL3)

PGUT:

117659626(CASTOR1)

APRI:

131185766(CASTOR1)

PTEX:

113448084(CASTOR1)

NSS:

113423290

VKO:	123032796(CASTOR1)

PMUA:

114586439(CASTOR1)

PRAF:

128404071(CASTOR1)

ZVI:	118076182(CASTOR1)

HCG:	128338107(CASTOR1)

GJA:	107122284(GATSL3)

STOW:

125443036(CASTOR1)

EMC:	129341514(CASTOR1)

XLA:	446432(castor1.L)

XTR:	100125101(castor1)

NPR:	108786254(GATSL3)

RTEM:

120939647(CASTOR1)

BBUF:

120988915(CASTOR1)

BGAR:

122933529(CASTOR1)

MUO:	115480351(CASTOR1)

GSH:	117365908(CASTOR1)

DRE:	449937(castor1)

SRX:	107726730 107755828

SANH:

107704487

SGH:	107599144(gatsl3)

CCAR:

109075006 109078597 109110229

CAUA:

113068106 113072288 113072336

CGIB:

127958124 128014083 128014091 128014147

PTET:

122346205(castor1)

LROH:

127165585(castor1)

OMC:	131541421(castor1)

PPRM:

120470252(castor1)

RKG:	130088126(castor1)

MAMB:

125267317(castor1)

CIDE:

127513253

MASI:

127430511 127437845

TROS:

130567633(castor1)

TDW:	130419960(castor1)

MANU:

129439680(castor1)

IPU:	108255989(castor1)

IFU:	128599024(castor1)

PHYP:

113537134

SMEO:

124380410(castor1)

TFD:	113653371(castor1)

TVC:	132854966(castor1)

TRN:	134335541(castor1)

AMEX:

103038945(castor1)

CMAO:

118827188(castor1)

EEE:	113577754(castor1)

CHAR:

122130956(castor1)

TRU:	101067357(castor1)

TFS:	130525477(castor1)

TNG:	GSTEN00029050G001

LCO:

104923684

TBEN:

117473190(castor1)

CGOB:

115014091(castor1)

PGEO:

117453053(castor1)

GACU:

117552073(castor1)

EMAC:

134873746(castor1)

ELY:	117251910(castor1)

EFO:	125890135(castor1)

PLEP:

121944184(castor1)

SLUC:

116054202(castor1)

ECRA:

117945124(castor1)

ESP:

116690133

PFLV:

114556351

GAT:	120830807(castor1)

PPUG:

119225088(castor1)

AFB:	129101263(castor1)

CLUM:

117736335(castor1)

PSWI:

130196528(castor1)

MSAM:

119891984(castor1)

SCHU:

122876408(castor1)

CUD:	121509314(castor1)

ALAT:

119020167(castor1)

MZE:	101487129(castor1)

ONL:	100696475(castor1)

OAU:	116325957(castor1)

OLA:

101155605

OML:	112148510(castor1)

CSAI:

133451476(castor1)

XMA:	102233594(castor1)

XCO:

114154964

XHE:

116730129

PRET:

103469873

PFOR:

103134952(gatsl3)

PLAI:

106945255(gatsl3)

PMEI:

106917024 106919451

GAF:	122828738(castor1)

PPRL:

129365982(castor1)

CVG:	107087340(gatsl3)

CTUL:

119788920(castor1)

GMU:	124877820(castor1)

NFU:

107386251

KMR:	108246928(castor1)

ALIM:

106519447

NWH:	119413185(castor1)

AOCE:

111572553(castor1)

MCEP:

125012522(castor1)

CSEM:

103397848

POV:	109636952(gatsl3)

SSEN:

122769684(castor1)

HHIP:

117768190(castor1)

HSP:	124852452(castor1)

PPLT:

128438878(castor1)

SMAU:

118313809(castor1)

LCF:	108872893(castor1)

SDU:

111227373

SLAL:

111663069

XGL:	120805520(castor1)

HCQ:	109525311(gatsl3)

SSCV:

125994136

SBIA:

133499807(castor1)

PEE:	133400291(castor1)

PTAO:

133474804(castor1)

BPEC:

110155027(castor1)

MALB:

109959155

BSPL:

114862389(castor1)

SJO:	128365459(castor1)

SASA:

100380530(gats) 106585238(gatsl3)

STRU:

115164135 115200500

OTW:	112248860 112262567

OMY:	110526015 110535112

OGO:	124034046 124036584

ONE:	115111914 115140340

OKI:	109883567 109896182

OKE:	118358569 118393528(castor1)

SALP:

111958010 111974710

SNH:	120043805 120063403

CCLU:

121530775 121585215(castor1)

ELS:

105024681

SFM:	108927278(castor1)

PKI:

111852740

AANG:

118206778(castor1)

LOC:	102690157(gatsl3)

PSPA:

121297325 121299872

ARUT:

117428475 117963196

PSEX:

120541599(castor1)

LCM:	102354270(GATSL3)

CMK:	103184340(castor1)

RTP:

CPLA:

HOC:

LERI:

XEN:

Reference

PMID:26972053

Authors

Chantranupong L, Scaria SM, Saxton RA, Gygi MP, Shen K, Wyant GA, Wang T, Harper JW, Gygi SP, Sabatini DM

Title

The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway.

Journal

Cell 165:153-164 (2016)
DOI:10.1016/j.cell.2016.02.035

Sequence

[hsa:652968]

LinkDB

DBGET integrated database retrieval system