KEGG ORTHOLOGY: K23958

ORTHOLOGY: K23958

Entry

K23958                      KO

Symbol

INF2

Name

inverted formin-2

Pathway

map04820

Cytoskeleton in muscle cells

Disease

H00264

Charcot-Marie-Tooth disease

H00626

Focal segmental glomerulosclerosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    K23958  INF2; inverted formin-2
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K23958  INF2; inverted formin-2
Cytoskeleton proteins [BR:ko04812]
Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Formins
     K23958  INF2; inverted formin-2

Genes

HSA:	64423(INF2)

PTR:	101059574(INF2)

PPS:	100970144(INF2)

GGO:	101124556(INF2)

PON:	100172485(INF2)

NLE:	100593510(INF2)

HMH:	116485142(INF2)

MCC:	706242(INF2)

MCF:	102140963(INF2)

MTHB:

126959406

MNI:	105489925(INF2)

CSAB:

103229780(INF2)

CATY:

105596766(INF2)

PANU:

100999829(INF2)

TGE:	112628545(INF2)

MLEU:

105541753(INF2)

RRO:	104673060(INF2)

RBB:	108521867 108521882 108528766

TFN:	117071290(INF2)

PTEH:

111538336(INF2)

CANG:

105518415

CJC:	100402629(INF2)

SBQ:

101036433

CIMI:

108287185(INF2)

CSYR:

103257726(INF2)

MMUR:

105861098(INF2)

LCAT:

123643764(INF2)

PCOQ:

105812609

OGA:	100946809(INF2)

MMU:	70435(Inf2)

MCAL:

110306811(Inf2)

MPAH:

110324102

RNO:	362790(Inf2)

MCOC:

116081120(Inf2)

ANU:	117697530(Inf2)

MUN:	110558965(Inf2)

CGE:

100751534

MAUA:

101827131(Inf2)

PROB:

127231183(Inf2)

PLEU:

114703048(Inf2)

MORG:

121434404(Inf2)

MFOT:

126509090

AAMP:

119819481(Inf2)

NGI:	103724396(Inf2)

HGL:	101702688(Inf2)

CPOC:

100713711(Inf2)

CCAN:

109691808(Inf2)

DORD:

105986710(Inf2)

DSP:	122101268(Inf2)

PLOP:

125363435 125363436

NCAR:

124976793

MMMA:

107151063(Inf2)

OCU:

103351027

OPI:

101535694

TUP:

106736157

GVR:	103596386(INF2)

CFA:	102153864(INF2)

CLUD:

112657144(INF2)

VVP:	112930302 112930307

VLG:	121492946(INF2)

NPO:	129495899(INF2)

AML:

100467275

UMR:	103676913(INF2)

UAH:	113267194(INF2)

UAR:	123778654(INF2)

ELK:

111148680

LLV:

125103686

MPUF:

101678570(INF2)

MNP:	132000308(INF2)

MLK:	131837049(INF2)

NVS:	122893044(INF2)

ORO:	101382099(INF2)

EJU:	114206515(INF2)

ZCA:	113909119(INF2)

MLX:	118002034(INF2)

NSU:	110571693(INF2)

LWW:

115942695

FCA:	101087413(INF2)

PYU:	121032357(INF2)

PCOO:

112855910

PBG:	122467825(INF2)

PVIV:

125168564(INF2)

LRUF:

PPAD:

PUC:

AJU:

HHV:	120247766(INF2)

BTA:	538493(INF2)

BOM:

106701005

BBUB:

102399371(INF2)

BBIS:

104983142

CHX:

102185402

OAS:	101103676(INF2)

BTAX:

128066541(INF2)

ODA:	120875133(INF2)

CCAD:

122454990(INF2)

MBEZ:

129550703(INF2)

SSC:	100623151(INF2)

CFR:	102512305(INF2)

CBAI:

105079971

CDK:	105104854(INF2)

BACU:

103012583(INF2)

BMUS:

118890247(INF2)

OOR:	101272551(INF2)

DLE:	111176012(INF2)

PCAD:

102980968(INF2)

PSIU:

116749272(INF2)

ECB:	100061064(INF2)

EPZ:	103540250 103540251

EAI:	106839599(INF2)

MMYO:

118655030(INF2)

PKL:	118714855(INF2)

EFUS:

114228801(INF2)

MNA:

107542382

DRO:	112311660(INF2)

SHON:

118988411(INF2)

AJM:	119063104(INF2)

PDIC:

114493214(INF2)

PHAS:

123808588(INF2)

MMF:	118616123(INF2)

PPAM:

129066176(INF2)

HAI:	109381014(INF2)

RFQ:	117023741(INF2)

PALE:

102889544(INF2)

PGIG:

120613955(INF2)

RAY:	107498398(INF2)

TOD:	119239479(INF2)

SETR:

126033367(INF2)

LAV:	100659619(INF2)

TMU:

101359716

ETF:

123521440

DNM:

101419816

MDO:	100020063(INF2)

GAS:	123237617(INF2)

SHR:	100918767(INF2)

AFZ:

127549864

PCW:	110203045 110203046

OAA:	100092805(INF2)

GGA:	423492(INF2)

PCOC:

116228802 116228803

MGP:	100539970(INF2) 104911253

CJO:	107315268 107315292

TPAI:

LMUT:

NMEL:

APLA:

ACYG:

CATA:

AFUL:

116489331(INF2)

TGU:	100225780(INF2) 101234217

LSR:

110469797

SCAN:

103826865

PMOA:

120503797(INF2) 120503872

OTC:	121332911(INF2)

PRUF:

121358247(INF2)

GFR:

102038614

FAB:

101808027

OMA:	130254113(INF2)

PMAJ:

107205720(INF2) 109022677

CCAE:

111929762 111929764(INF2)

CBRC:

108445371

ETL:	114066720(INF2)

ZAB:	102061198 102069993(INF2)

SVG:	106850509(INF2)

HRT:	120754147 120754180

FPG:	106112140 106112141

FCH:

CLV:

EGZ:

PCRI:

PLET:

EHS:

PCAO:

ACUN:

TALA:

PADL:

103920005 103920558 103920567

AFOR:

ACHC:

HALD:

HLE:

AGEN:

GCL:

CCRI:

CSTI:

MUI:

BREG:

FGA:

GSTE:

LDI:

MNB:

OHA:

NNT:

SHAB:

PGUU:

ACAR:

CPEA:

104387159(ADSSL1)

AVIT:

104269797

RTD:

128908903

CUCA:

104057774(INF2)

TEO:

104379512

AAM:	106483095 106483096

AROW:

112970976(INF2)

NPD:

112955349

SCAM:

104144535

ASN:	102368845 102372125

AMJ:

102567786

CPOO:

109320623

GGN:

109298408

PSS:	102455347 102455585

CMY:	102946431(INF2) 102946657

CPIC:

TST:

CABI:

MRV:

PVT:	110069790(INF2)

SUND:

121935119(INF2)

PMUR:

107286274(INF2)

CTIG:

120312172(INF2)

TSR:	106541025(INF2) 106554731

PGUT:

117666043(INF2)

APRI:

131187967(INF2)

VKO:

123026434

PMUA:

114605910 114606701(INF2)

PRAF:

128399741(INF2)

ZVI:	118080029(INF2)

STOW:

125426389 125426390

EMC:	129324039(INF2)

XLA:	414513(inf2.S) 495032(inf2.L)

XTR:	780046(inf2)

NPR:

108786735

RTEM:

120920316(INF2)

BBUF:

120982376(INF2)

BGAR:

122921244(INF2)

MUO:

115477492

GSH:	117363632(INF2)

SRX:	107716040 107745357

SANH:

107678755 107703640

SGH:	107564026(inf2)

CCAR:

109078703

CAUA:

113090710 113117763 113117770

CGIB:

127976559

PTET:

122334415(inf2)

PPRM:

120473223(inf2)

RKG:	130085682(inf2)

MAMB:

125269255(inf2)

CIDE:

127498241

TROS:

130559974(inf2)

TDW:	130436898(inf2)

MANU:

129418032(inf2)

IPU:

108269962

IFU:	128612334(inf2)

PHYP:

113529670(inf2)

SMEO:

124390102(inf2)

TFD:	113660282(inf2)

TVC:	132852828(inf2)

AMEX:

103031516 103040341

TRU:	101078297(inf2)

TFS:

130513160

TNG:	GSTEN00032400G001

LCO:

104934450

NCC:	104949708(inf2)

TBEN:

117470067(inf2)

CGOB:

115004607 115027069

PGEO:

117467918

GACU:

117550195(inf2)

EMAC:

134881576(inf2)

ELY:	117266922 117270473

EFO:	125897201 125900669(inf2)

PLEP:

121953403(inf2) 121955255

SLUC:

116035676(inf2) 116061804

ECRA:

117935553

ESP:	116670565(inf2)

PFLV:

114546927 114572912

GAT:	120814725 120832520(inf2)

PPUG:

119194563 119227485

AFB:	129103000 129107520

CLUM:

117751598(inf2)

PSWI:

130201327

MSAM:

119904770 119904771 119909840 119909843(inf2)

SCHU:

122861348(inf2) 122862692

CUD:	121526201(inf2)

ALAT:

119004903(inf2)

MZE:	105940681 106676086 106676873 112430076 112432444 112432445

ONL:	100697518 100704696

OAU:	116322299(inf2) 116324105

OLA:	101164771 101173754(inf2)

OML:	112142415(inf2) 112158109

CSAI:

133418705 133462921(inf2)

XMA:

102223151

XCO:	114134357(inf2)

XHE:	116708736(inf2) 116733883

PRET:

103457122 103458541(inf2)

PFOR:

103153709 103153741

PLAI:

106953640(inf2) 106961527

PMEI:

106914507 106915012

GAF:	122825606 122845984

PPRL:

129365453(inf2)

CVG:	107080895 107099991

CTUL:

119779511 119787540

GMU:	124855881 124882055

NFU:	107377903 107377904 107392462(inf2)

KMR:	108235442(inf2) 108242570

ALIM:

106520034 106528653

NWH:	119418398 119427482(inf2)

AOCE:

111570518(inf2) 111576881

MCEP:

125023414(inf2)

CSEM:

103389267(inf2)

POV:

109628123

SSEN:

122762192(inf2)

HHIP:

117755633(inf2)

HSP:	118116207(inf2)

LCF:	108890029 108892596

SDU:	111225986 111226045(inf2) 111231715

SLAL:

111645952 111673266(inf2)

XGL:	120788618 120795332 120795339(inf2)

HCQ:	109516040(inf2)

SSCV:

125981329

SBIA:

133512947

PEE:	133412977(inf2)

PTAO:

133487762

BPEC:

110155446(inf2)

MALB:

109968339(inf2) 109974468

BSPL:

114848924

SJO:

128377442

SASA:

100380739(inf2) 106571473 106582786 106607633 106610851

STRU:

115162381 115172663 115174702 115191776

OTW:	112217660 112256644 112261835

OMY:	110497966 110505489 110521060 110529217

OGO:	123995159 124046415

ONE:	115107833 115138459 115139340 115146257

OKI:	109894537 109900812 109904003

OKE:	118362437 118368353 118398586

SALP:

111954108 111963233 111968778 111968779 111973318

SNH:	120019307 120024457 120060241

CCLU:

121539235 121544955 121548850 121552459

ELS:	105015654(inf2)

SFM:	108919632(inf2)

PKI:	111838906(inf2)

AANG:

118229048 118230733 118230891

LOC:	102690070(inf2)

PSPA:

121324130 121324335 121330222 121330223

LCM:	102359528(INF2)

CMK:	103175288(inf2)

RTP:

109915960

CPLA:

122553563

HOC:	132817928(inf2) 132818320

LERI:

129700285(inf2)

BFO:	118418763 118419076

BBEL:

CIN:

SCLV:

SPU:

APLC:

DME:	Dmel_CG33556(form3)

DER:

6544618

DSE:

6611097

DSI:	Dsimw501_GD13991(Dsim_GD13991)

DYA:	Dyak_GE21592

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI13292

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:	119672350 119679353

MDE:	101891853 101899840 131806888

SCAC:

106088638 106092838

LCQ:	111679388 111679405

LSQ:	119604918 119604921

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AAG:

AALB:

CQU:	CpipJ_CPIJ007323

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

AROA:

TCA:	658775 658801

DPA:

SOY:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_215226

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:	105383510 105387629

PGW:

126380291

CFEL:

113378522

CCRN:

123299267

API:	100159987 100162660

DNX:	107162912 107173157

AGS:	114119052 114120782

RMD:	113550106 113551739

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:	111043944 111046660 111052549 111053481 111056661 120355644

HVI:

124360594

MQU:

128991742

PHU:	Phum_PHUM491810

FOC:	113203064 113205356

TPAL:

117639881 117650090

ZNE:	110833390 110834903

CSEC:

111866052 111872599

BROR:

134537410

FCD:

110851086

DPX:	DAPPUDRAFT_105824

DMK:

116928274

DPZ:

124310825

PVM:	113802820 113802830 113819013

PJA:	122243442 122256223

PCHN:

PMOO:

HAME:

PCLA:

PTRU:

HAZT:

EAF:

LSM:

PPOI:

DSV:	119449582 119449828

RSAN:

119381089 119382796

RMP:

119169249

VDE:	111244069 111247558

VJA:	111261148 111268158

TUT:

107371226

DPTE:

113791902

DFR:

124498979

CSCU:

111620257 111629655 111642243

PTEP:

107438137 107455600

SDM:	118195464 118200800

LOA:	LOAG_16452

HRO:	HELRODRAFT_170303 HELRODRAFT_187875

LGI:	LOTGIDRAFT_171217 LOTGIDRAFT_224207

PCAN:

112559270 112559598 112560117 112560873

BGT:	106050830 106054548 106069394

GAE:	121374102 121374313 121374345 121374446

HRF:	124144206 124144208 124144211 124149612

HRJ:	124270821 124272658 124272950 124273124

CRG:	105327750 105336275 105346839 105346870 105346876

MYI:	110444537 110444606 110449517

PMAX:

117328963 117329591 117329594

MMER:

123557467 123557491 123557499 123557500 123557862 123557902 123558488

OBI:	106868073 106875212 106876454 106877725

OSN:	115214240 115218242 115218267 115222695

LAK:	106150526 106151447 106153007

NVE:	5497678 5506774

EPA:

110243504

ATEN:

116295681

ADF:	107329743 107340187

AMIL:

114970435

PDAM:

113686464

SPIS:

111332145

DGT:	114521386 114521401

XEN:

124445525

HMG:

100213938

AQU:	100638768 100638771

MBR:	MONBRDRAFT_26231

SRE:	PTSG_12100

» show all

Reference

PMID:20023659

Authors

Brown EJ, Schlondorff JS, Becker DJ, Tsukaguchi H, Tonna SJ, Uscinski AL, Higgs HN, Henderson JM, Pollak MR

Title

Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis.

Journal

Nat Genet 42:72-6 (2010)
DOI:10.1038/ng.505

Sequence

[hsa:64423]

LinkDB

DBGET integrated database retrieval system