Entry
Symbol
MORC
Name
MORC family CW-type zinc finger protein
Disease
H00264 Charcot-Marie-Tooth disease
H02685 Developmental delay with neuropsychiatric disorders
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins
K24135 MORC; MORC family CW-type zinc finger protein
Chromosome and associated proteins [BR:ko03036 ]
Eukaryotic type
Chromatin remodeling factors
Other chromatin remodeling factors
K24135 MORC; MORC family CW-type zinc finger protein
BRITE hierarchy
Genes
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Taxonomy UniProt
Reference
Authors
Inoue N, Hess KD, Moreadith RW, Richardson LL, Handel MA, Watson ML, Zinn AR
Title
New gene family defined by MORC, a nuclear protein required for mouse spermatogenesis.
Journal
Sequence
Reference
Authors
Zanni G, Nardella M, Barresi S, Bellacchio E, Niceta M, Ciolfi A, Pro S, D'Arrigo S, Tartaglia M, Bertini E
Title
De novo p.T362R mutation in MORC2 causes early onset cerebellar ataxia, axonal polyneuropathy and nocturnal hypoventilation.
Journal
Sequence
Reference
Authors
Andrews FH, Tong Q, Sullivan KD, Cornett EM, Zhang Y, Ali M, Ahn J, Pandey A, Guo AH, Strahl BD, Costello JC, Espinosa JM, Rothbart SB, Kutateladze TG
Title
Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.
Journal
Sequence
Reference
Authors
Liggins AP, Cooper CD, Lawrie CH, Brown PJ, Collins GP, Hatton CS, Pulford K, Banham AH
Title
MORC4, a novel member of the MORC family, is highly expressed in a subset of diffuse large B-cell lymphomas.
Journal
Sequence
Reference
Authors
Tchasovnikarova IA, Timms RT, Douse CH, Roberts RC, Dougan G, Kingston RE, Modis Y, Lehner PJ
Title
Hyperactivation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2.
Journal
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