KEGG ORTHOLOGY: K24172

ORTHOLOGY: K24172

Entry

K24172                      KO

Symbol

CAND2, TIP120B

Name

cullin-associated NEDD8-dissociated protein 2

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K24172  CAND2, TIP120B; cullin-associated NEDD8-dissociated protein 2
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Multi subunit type E3 associated proteins
    K24172  CAND2, TIP120B; cullin-associated NEDD8-dissociated protein 2

Genes

HSA:	23066(CAND2)

PTR:	460186(CAND2)

PPS:	100970507(CAND2)

GGO:	101138292(CAND2)

PON:	100439310(CAND2)

NLE:	100581821(CAND2)

HMH:	116466756(CAND2)

MCC:	694326(CAND2)

MCF:	102127715(CAND2)

MTHB:

126949050

MNI:	105477733(CAND2)

CSAB:

103228034(CAND2)

CATY:

105585807(CAND2)

PANU:

101006707(CAND2)

TGE:	112619134(CAND2)

MLEU:

105542181(CAND2)

RRO:	104661490(CAND2)

RBB:	108544753(CAND2)

TFN:	117083279(CAND2)

PTEH:

111526774(CAND2)

CANG:

105519105(CAND2)

CJC:	100385170(CAND2)

SBQ:	101032927(CAND2)

CIMI:

108284631(CAND2)

CSYR:

103256784

MMUR:

105882682(CAND2)

LCAT:

123638136(CAND2)

PCOQ:

105819021(CAND2)

OGA:	100940428(CAND2)

MMU:	67088(Cand2)

MCAL:

110296710(Cand2)

MPAH:

110316321(Cand2)

RNO:	192226(Cand2)

MCOC:

116099436(Cand2)

ANU:	117715301(Cand2)

MUN:	110550821(Cand2)

CGE:	100770365(Cand2)

MAUA:

101842926(Cand2)

PROB:

127236130(Cand2)

PLEU:

114689638(Cand2)

MORG:

121435179(Cand2)

MFOT:

126505505

AAMP:

119807404(Cand2)

NGI:	103751453(Cand2)

HGL:	101723240(Cand2)

CPOC:

100720670(Cand2)

CCAN:

109693976 109694939(Cand2)

DORD:

105981302(Cand2)

DSP:	122108016(Cand2)

PLOP:

125358823(Cand2)

NCAR:

124971012

MMMA:

107150138(Cand2)

OCU:

100346969

OPI:	101534700(CAND2)

TUP:	102477515(CAND2)

GVR:	103602613(CAND2)

CFA:	484646(CAND2)

CLUD:

112661347(CAND2)

VVP:	112933721(CAND2)

VLG:	121495000(CAND2)

NPO:	129521755(CAND2)

AML:	100484191(CAND2)

UMR:	103669638(CAND2)

UAH:	113257195(CAND2)

UAR:	123802012(CAND2)

ELK:

111144149

LLV:

125108398

MPUF:

101692277(CAND2)

MNP:	132011573(CAND2)

MLK:	131824242(CAND2)

NVS:	122909189(CAND2)

ORO:	101372641(CAND2)

EJU:	114207685(CAND2)

ZCA:	113916918(CAND2)

MLX:	118005826(CAND2)

NSU:	110584846(CAND2)

LWW:	102729455(CAND2)

FCA:	101096554(CAND2)

PYU:	121041236(CAND2)

PCOO:

112858336(CAND2)

PBG:	122487523(CAND2)

PVIV:

125161078(CAND2)

LRUF:

124524739

PTG:	102954421(CAND2)

PPAD:

109257486(CAND2)

PUC:

125929642

AJU:

106977113

HHV:	120231299(CAND2)

BTA:	533826(CAND2)

BOM:	102267161(CAND2)

BIU:

109576109

BBUB:

102411058(CAND2)

BBIS:

105004787(CAND2)

CHX:	108638633(CAND2)

OAS:	101107312(CAND2)

BTAX:

128050320(CAND2)

ODA:	120868114(CAND2)

CCAD:

122425146(CAND2)

MBEZ:

129547716(CAND2)

SSC:	100525717(CAND2)

CFR:	102503479(CAND2)

CBAI:

105067477(CAND2)

CDK:	105093097(CAND2)

VPC:	102541221(CAND2)

BACU:

103016022(CAND2)

BMUS:

118904531(CAND2)

LVE:	103070302(CAND2)

OOR:	101273432(CAND2)

DLE:	111168942(CAND2)

PCAD:

102990624

PSIU:

116761856(CAND2)

NASI:

112407248(CAND2)

ECB:	100050966(CAND2)

EPZ:	103558177(CAND2)

EAI:	106829351(CAND2)

MYB:	102253293(CAND2)

MYD:	102774174(CAND2)

MMYO:

118668080(CAND2)

MLF:	102432900(CAND2)

PKL:	118715230(CAND2)

EFUS:

103295770(CAND2)

MNA:	107534727(CAND2)

DRO:	112301256(CAND2)

SHON:

118990363(CAND2)

AJM:	119044817(CAND2)

PDIC:

114501949(CAND2)

PHAS:

123814401(CAND2)

MMF:	118633428(CAND2)

PPAM:

129088298(CAND2)

HAI:	109384576(CAND2)

RFQ:	117036977(CAND2)

PALE:

102893920(CAND2)

PGIG:

120621481(CAND2)

PVP:	105299018(CAND2)

RAY:	107498675(CAND2)

MJV:	108389888(CAND2)

TOD:	119255750(CAND2)

SARA:

101545771(CAND2)

SETR:

125998036(CAND2)

LAV:	100655441(CAND2)

TMU:

101358269

ETF:	101655647(CAND2)

DNM:	101422826(CAND2)

MDO:	100015450(CAND2)

GAS:	123239754(CAND2)

SHR:	100915573(CAND2)

AFZ:

127552185

PCW:	110204896(CAND2)

OAA:

100073450

GGA:	416121(CAND2)

PCOC:

MGP:

CJO:

TPAI:

LMUT:

NMEL:

APLA:

ACYG:

CATA:

AFUL:

TGU:

LSR:

SCAN:

PMOA:

OTC:

PRUF:

GFR:

FAB:

OMA:

PHI:	102105797(CAND2)

PMAJ:

CCAE:

CCW:

CBRC:

ETL:

ZAB:

ACHL:

103807089(CAND2)

SVG:

MMEA:

HRT:

FPG:

FCH:

CLV:

EGZ:	104121780(CAND2)

NNI:

104016957

PCRI:

104032242(CAND2)

PLET:

104617685(CAND2)

EHS:	104514463(CAND2)

PCAO:

ACUN:

TALA:

PADL:

AFOR:

ACHC:

HALD:

HLE:	104833532(CAND2)

AGEN:

126049622

GCL:

127021383

CCRI:

104162256(CAND2)

CSTI:

CMAC:

MUI:

BREG:

FGA:	104082188(CAND2)

GSTE:

104264114(CAND2)

LDI:	104353944(CAND2)

MNB:

103779918

OHA:	104334365(CAND2)

NNT:

SHAB:

DPUB:

PGUU:

ACAR:

CPEA:

AVIT:

104278994(CAND2)

CVF:

104284527

RTD:

128915474

CUCA:

104063594

TEO:	104382957(CAND2)

BRHI:

104499127

AAM:	106494631(CAND2)

AROW:

112970429

NPD:

112958643

TGT:	104574025(CAND2)

DNE:

112982910

SCAM:

104148117

ASN:

102373478

AMJ:	102561116(CAND1)

CPOO:

GGN:

PSS:

CMY:

CCAY:

CPIC:

TST:

CABI:

MRV:

ACS:

ASAO:

PVT:

SUND:

PBI:

PMUR:

CTIG:

TSR:

PGUT:

APRI:

PTEX:

NSS:

VKO:

PRAF:

ZVI:

HCG:

GJA:

STOW:

EMC:

XLA:

XTR:	100492789(cand2)

NPR:

RTEM:

BBUF:

BGAR:

MUO:

GSH:

DRE:	555955(cand2)

SRX:	107719941 107720354

SANH:

107657311 107691187

SGH:	107557972 107562724

CCAR:

109052145

CAUA:

113065086

CGIB:

127942615

PTET:

122327690(cand2)

LROH:

127153951(cand2)

OMC:	131530727(cand2)

PPRM:

120495398(cand2)

RKG:	130094230(cand2)

MAMB:

125253334(cand2)

CIDE:

127521660

MASI:

127438189 127439038

TROS:

130549120(cand2)

TDW:	130430107(cand2)

MANU:

129452783(cand2)

IPU:

108255156

IFU:	128625072(cand2)

PHYP:

113537902

SMEO:

124402058(cand2)

TFD:	113656523(cand2)

TVC:	132838053(cand2)

AMEX:

103033844

CMAO:

118799461(cand2)

EEE:

113583711

CHAR:

105895938(cand2)

TRU:

101062438

TFS:

130523782

LCO:

104931982

TBEN:

117486830(cand2)

CGOB:

PGEO:

GACU:

EMAC:

ELY:	117256670(cand2)

EFO:	125888034(cand2)

PLEP:

121960804

SLUC:

116034602(cand2)

ECRA:

117943455(cand2)

ESP:

116687807

PFLV:

114553933

GAT:	120835231(cand2)

PPUG:

119194215(cand2)

AFB:	129106039(cand2)

CLUM:

117731464(cand2)

MSAM:

119883431 119886286(cand2)

SCHU:

122869936(cand2)

CUD:	121528064(cand2)

ALAT:

119020556(cand2)

MZE:

101484714

ONL:

100694792

OAU:	116310179(cand2)

OLA:

101161115

OML:	112141946(cand2)

CSAI:

133448472(cand2)

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122834561(cand2)

PPRL:

129372823(cand2)

CVG:

107100233

CTUL:

119797222(cand2)

GMU:	124857402(cand2)

NFU:

107375928

KMR:	108244949(cand2)

ALIM:

106525031

NWH:	119412656(cand2)

AOCE:

111568401

MCEP:

125007355(cand2)

CSEM:

103386799

POV:

109640273

SSEN:

122768685(cand2)

HHIP:

117762216(cand2)

HSP:

118104766

SMAU:

118309588(cand2)

LCF:	108901496(cand2)

SDU:

111224398

SLAL:

111644264

XGL:	120807307(cand2)

BPEC:

110163446

MALB:

109952613

BSPL:

114855433(cand2)

SJO:	128356220(cand2)

SASA:

106566202 106566217

STRU:

115207283

OTW:	112221964(cand2)

OMY:	110494807(cand2)

OGO:	124003957(cand2)

ONE:

115125162

OKI:

109881822

OKE:	118373542(cand2)

SALP:

112073245

SNH:	120036317(cand2)

CCLU:

121574714(cand2)

ELS:

105005645

SFM:

108931135

PKI:

111843609

AANG:

118211284(cand2)

LOC:	102686133(cand2)

PSPA:

121298041

ARUT:

117411771 117413728 117963559

PSEX:

120540400(cand2)

LCM:	102353799(CAND2)

CMK:	103176739(cand2)

RTP:

CPLA:

HOC:

LERI:

MSYM:

Reference

PMID:10441524

Authors

Aoki T, Okada N, Ishida M, Yogosawa S, Makino Y, Tamura TA

Title

TIP120B: a novel TIP120-family protein that is expressed specifically in muscle tissues.

Journal

Biochem Biophys Res Commun 261:911-6 (1999)
DOI:10.1006/bbrc.1999.1147

Sequence

[rno:192226]

Reference

PMID:17242400

Authors

Shiraishi S, Zhou C, Aoki T, Sato N, Chiba T, Tanaka K, Yoshida S, Nabeshima Y, Nabeshima Y, Tamura TA

Title

TBP-interacting protein 120B (TIP120B)/cullin-associated and neddylation-dissociated 2 (CAND2) inhibits SCF-dependent ubiquitination of myogenin and accelerates myogenic differentiation.

Journal

J Biol Chem 282:9017-28 (2007)
DOI:10.1074/jbc.M611513200

Sequence

[mmu:67088]

LinkDB

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