KEGG ORTHOLOGY: K24466

ORTHOLOGY: K24466

Entry

K24466                      KO

Symbol

NOTCH2NL

Name

Notch homolog 2 N-terminal-like protein

Disease

H01577

Essential tremor

H02513

Oculopharyngodistal myopathy

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified
    K24466  NOTCH2NL; Notch homolog 2 N-terminal-like protein
Domain-containing proteins not elsewhere classified [BR:ko04990]
EGF-like domain-containing proteins
  hEGF / cEGF domain-containing proteins
   K24466  NOTCH2NL; Notch homolog 2 N-terminal-like protein

Genes

HSA:	100996717(NOTCH2NLC) 100996763(NOTCH2NLB) 388677(NOTCH2NLA)

MLEU:

CIMI:

CCAN:

UAR:

AJM:

MGP:

AAM:

Reference

PMID:29856954

Authors

Fiddes IT, Lodewijk GA, Mooring M, Bosworth CM, Ewing AD, Mantalas GL, Novak AM, van den Bout A, Bishara A, Rosenkrantz JL, Lorig-Roach R, Field AR, Haeussler M, Russo L, Bhaduri A, Nowakowski TJ, Pollen AA, Dougherty ML, Nuttle X, Addor MC, Zwolinski S, Katzman S, Kriegstein A, Eichler EE, Salama SR, Jacobs FMJ, Haussler D

Title

Human-Specific NOTCH2NL Genes Affect Notch Signaling and Cortical Neurogenesis.

Journal

Cell 173:1356-1369.e22 (2018)
DOI:10.1016/j.cell.2018.03.051

Sequence

[hsa:388677 100996717 100996763]

LinkDB

DBGET integrated database retrieval system