KEGG ORTHOLOGY: K25518

ORTHOLOGY: K25518

Entry

K25518                      KO

Symbol

E4.1.1.126

Name

anhydromevalonate phosphate decarboxylase [EC:4.1.1.126]

Pathway

map00900

Terpenoid backbone biosynthesis

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

Module

M00849

C5 isoprenoid biosynthesis, mevalonate pathway, archaea

Reaction

R12895

trans-anhydromevalonate 5-phosphate carboxy-lyase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    K25518  E4.1.1.126; anhydromevalonate phosphate decarboxylase
Enzymes [BR:ko01000]
4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.126  anhydromevalonate phosphate decarboxylase
     K25518  E4.1.1.126; anhydromevalonate phosphate decarboxylase

Other DBs

COG:

COG0043

Genes

BGK:	IC762_29465

MJA:

MJ_1133

MFE:	Mefer_0287

MVU:	Metvu_1374

MFS:	MFS40622_0069

MIF:	Metin_1023

MJH:	JH146_0714

MESG:

MLAUSG7_0678

MESA:

MLASG1_0345

MIG:	Metig_0474

MMP:

MMP1288

MMQ:	MmarC5_0305

MMX:	MmarC6_1386

MMZ:	MmarC7_0533

MMD:

GYY_07275

MMAK:

MMKA1_15130

MMAO:

MMOS7_13950

MMAD:

MMJJ_15550(ubiD)

MAE:

Maeo_0014

MVN:	Mevan_0598

MVO:	Mvol_0032 Mvol_0092

MOK:	Metok_1181

METF:

CFE53_03010

MTH:

MTH_1394

MMG:	MTBMA_c17800

MWO:	MWSIV6_1774

MTEE:

MTTB_15830

METC:

MTCT_1267

METE:

tca_01347(bsdC)

METZ:

METK:

MTHM:

METJ:

MST:

METB:

MEIS:

MRU:

MSI:

MEB:

MMIL:

MEYE:

MOL:

MARO:

METV:

MEL:	Metbo_0178

MEW:	MSWAN_2305

METH:

MBMB1_1946

MFC:

BRM9_2286

MFI:	DSM1535_1220

MCUB:

MSUB:

METN:

METT:

METO:

MEME:

MFEG:

MFV:

MKA:	MK0234(ubiD)

AFU:

AF_1643

AFG:	AFULGI_00018930

APO:	Arcpr_1653

AVE:	Arcve_0618

AST:	Asulf_01062

FPL:

GAC:

GAH:

PFU:

PFI:

PHO:	PH0963(PH0963)

PAB:

PAB1798

PYN:

PNA2_1640

PYA:	PYCH_04010

PYS:

Py04_0819

PYC:	TQ32_05685

TKO:

TK0929

TON:

TON_0392

TGA:	TGAM_1657(ubiD-2)

TSI:

TSIB_0620

TBA:	TERMP_00411

THE:

THA:

THM:

TLT:

THS:

TNU:

TEU:

TGY:	X802_01205

THV:	ADU37_CDS13680

TCH:	CHITON_0854

TPEP:

A0127_00490

TPIE:

A7C91_07975

TGG:	A3K92_04035

TCE:	A3L02_09380

TBS:	A3L01_02655

THH:	CDI07_02610

TSL:	A3L11_06600

TTD:	A3L14_04205

TPRF:

A3L09_05430

TRL:	A3L10_03925

TPAF:

A3L08_05655

THY:	A3L12_06085

TIC:	FH039_05000

TCQ:	TIRI35C_0756

THEM:

FPV09_04195

THEI:

K1720_06170

PPAC:

PAP_03940

MBA:	Mbar_A0716

MBY:	MSBRM_0329

MBW:	MSBRW_0285

MBAR:

MBAK:

MAC:

MMA:

MMAZ:

MMJ:	MSMAS_3141

MMAC:

MSMAC_3161

MVC:	MSVAZ_0315

MEK:	MSKOL_0299

MLS:	MSLAZ_0091

METM:

MSMTP_3039

MEF:	MSWH1_0173

MEQ:	MSWHS_0172

MSJ:	MSSAC_0232

MSZ:	MSSIH_0201

MSW:	MSSIT_0205

MTHR:

MSTHT_2039

MTHE:

MSTHC_1247

MHOR:

MSHOH_3878

MFZ:	AOB57_009510

MBU:	Mbur_1473(ubiD)

MMET:

MELO:

MMH:

MHAZ:

MPOT:

MEV:	Metev_2056

MZH:	Mzhil_1541

MPY:

Mpsy_2253

MZI:	HWN40_10870

MMAV:

RE476_12230

MSEB:

RE474_09120

MHZ:	Metho_2162

MEHF:

MmiHf6_15580(ubiD)

MEES:

MmiEs2_00940(ubiD)

MTP:

MCJ:

MHI:

MHU:

MRTJ:

MLA:

MEM:	Memar_2139

MBG:	BN140_1347(ubiD)

MEMA:

MMAB1_1716

MCHK:

MchiMG62_24480

MSUM:

OH143_04980

MRC:	R6Y96_01580

MPI:

MEND:

MEFW:

MAQE:

MFK:	E2N92_06905

MOU:	OU421_09615

MESB:

L1S32_00810

MANQ:

L1994_03860

MBN:

Mboo_0122

MFO:	Metfor_0250

MPL:

MPD:

MEZ:

RCI:

HALH:

HTSR_1039(ubiD)

HHSR:

HSR6_1072(ubiD)

HSU:	HLASF_0829(ubiD)

HSF:	HLASA_0826(ubiD)

HAHS:

HSRCO_1215(ubiD2)

HUT:

Huta_0617

HTI:	HTIA_0365(ubiD)

HALA:

Hrd1104_02520

HASV:

SVXHr_1977(ubiD)

HABN:

HBNXHr_1964(ubiD)

HDS:	HSR122_0652(ubiD)

HARC:

HARCEL1_02630

HDF:	AArcSl_1770(ubiD)

HAAA:

AArcCO_0144(ubiD)

MEAM:

MU439_04170

MEAE:

QEN48_05820

TAR:	TALC_00691

MAX:	MMALV_10070

MER:	MMINT_12400

MEAR:

Mpt1_c06960(ubiD)

MEUZ:

KRP56_03340

MARC:

AR505_1172

ABI:

Aboo_0767

ACF:	AciM339_0300

APE:

APE_2078

ACJ:

ACAM_1300

SMR:

Smar_0621

SHC:	Shell_0174

IHO:

IIS:

IPC:

DKA:

DFD:	Desfe_0219

DMU:	Desmu_0695

TAG:

Tagg_1156

IAG:

Igag_1939

THG:	TCELL_0126

HBU:

Hbut_1635

PFM:	Pyrfu_0192

PDL:	Pyrde_0504

PABI:

PARE:

PAI:

PIS:

PCL:

PAS:

PYR:

POG:

TNE:

PYW:	PYWP30_01477

CMA:

Cmaq_0422

TTN:	TTX_1591(ubiD)

TUZ:

TUZN_1947

VDI:

Vdis_2362

VMO:

VMUT_0714

VSO:	Vsou_21070

TPE:

Tpen_0404

THB:	N186_03050

TCB:	TCARB_1674

THF:	MA03_07925

THEL:

IG193_05515

ASC:

ASAC_1369

ACIA:

SE86_04525

CLG:	Calag_0755

FFO:	FFONT_1069

NMR:

Nmar_1597

NIR:	NSED_08645

NKR:	NKOR_08690

NID:	NPIRD3C_0457

NIN:	NADRNF5_0289(ubiD)

NIW:	Nisw_05905

NCL:	C5F47_08375

NOX:	C5F49_08260

NUE:	C5F50_11630

NIP:	NsoK4_00285

NZT:	NZOSNM25_000187

NCT:

NMSP_1539

NIC:	DSQ20_09285

NGA:	Ngar_c07630

NVN:	NVIE_013060

NEV:

NTE_02706

TAA:	NMY3_03586(bsdC)

NFN:	NFRAN_0939

NCV:

NCAV_0139

CSY:	CENSYa_1735

NBV:

T478_1315

TAH:	SU86_005060

NIU:	DSQ19_00980

NDV:

CCAI:

KCR:

BARC:

BARB:

FLT:	Sv326_0058

LOKI:

Lokiarch_22670(ubiD)

» show all

Reference

PMID:30224495

Authors

Hayakawa H, Motoyama K, Sobue F, Ito T, Kawaide H, Yoshimura T, Hemmi H.

Title

Modified mevalonate pathway of the archaeon Aeropyrum pernix proceeds via trans-anhydromevalonate 5-phosphate.

Journal

Proc Natl Acad Sci U S A 115:10034-10039 (2018)
DOI:10.1073/pnas.1809154115

Sequence

[ape:APE_2078]

Reference

PMID:31924615

Authors

Yoshida R, Yoshimura T, Hemmi H.

Title

Reconstruction of the "Archaeal" Mevalonate Pathway from the Methanogenic Archaeon Methanosarcina mazei in Escherichia coli Cells.

Journal

Appl Environ Microbiol 86:AEM.02889-19 (2020)
DOI:10.1128/AEM.02889-19

Sequence

[mma:MM_1526]

LinkDB

DBGET integrated database retrieval system