MODULE: M00099
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Entry
M00099 Pathway Module
Name
Sphingosine biosynthesis
Definition
K00654 K04708 (K04709,K04710,K24621,K24622,K23727) K04712 (K01441,K12348,K12349)
Diagram
Orthology
K00654
serine palmitoyltransferase [EC:
2.3.1.50
] [RN:
R01281
]
K04708
3-dehydrosphinganine reductase [EC:
1.1.1.102
] [RN:
R02978
]
K04709
very-long-chain ceramide synthase [EC:
2.3.1.297
] [RN:
R06517
]
K04710
sphingoid base N-stearoyltransferase [EC:
2.3.1.299
] [RN:
R06517
]
K24621
very-long-chain ceramide synthase [EC:
2.3.1.297
] [RN:
R06517
]
K24622
very-long-chain/ultra-long-chain ceramide synthase [EC:
2.3.1.297
2.3.1.298
] [RN:
R06517
]
K23727
sphingoid base N-palmitoyltransferase [EC:
2.3.1.291
] [RN:
R06517
]
K04712
sphingolipid 4-desaturase [EC:
1.14.19.17
] [RN:
R06519
]
K01441
,
K12348
,
K12349
ceramidase [EC:
3.5.1.23
] [RN:
R01494
]
Ortholog table
Taxonomy
Module table
Class
Pathway modules; Lipid metabolism; Lipid metabolism
BRITE hierarchy
Pathway
map00600
Sphingolipid metabolism
map01100
Metabolic pathways
Reaction
R01281
C00154
->
C02934
R02978
C02934
->
C00836
R06517
C00836
->
C12126
R06519
C12126
->
C00195
R01494
C00195
->
C00319
Compound
C00154
Palmitoyl-CoA
C02934
3-Dehydrosphinganine
C00836
Sphinganine
C12126
Dihydroceramide
C00195
N-Acylsphingosine
C00319
Sphingosine
LinkDB
All DBs
DBGET
integrated database retrieval system
