| Entry |
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| Name |
Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol
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| Definition |
K02552 K02551 K08680 K02549 K01911 K01661 K19222 K02548 K03183
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| Diagram |
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| Orthology |
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [EC: 2.2.1.9] [RN: R08165] 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [EC: 4.2.99.20] [RN: R08166] 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC: 2.5.1.74] [RN: R10757] |
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| Class |
Pathway modules; Metabolism of cofactors and vitamins; Cofactor and vitamin metabolism
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| Pathway |
| map00130 | Ubiquinone and other terpenoid-quinone biosynthesis |
| map01110 | Biosynthesis of secondary metabolites |
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| Reaction |
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| Compound |
| C16519 | 2-Succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate |
| C05817 | (1R,6R)-6-Hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate |
| C15547 | 1,4-Dihydroxy-2-naphthoyl-CoA |
| C03657 | 1,4-Dihydroxy-2-naphthoate |
| C05847 | all-trans-Polyprenyl diphosphate |
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| Reference |
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| Authors |
Chen M, Ma X, Chen X, Jiang M, Song H, Guo Z |
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| Title |
Identification of a hotdog fold thioesterase involved in the biosynthesis of menaquinone in Escherichia coli. |
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| Journal |
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| Reference |
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| Authors |
Joshi S, Fedoseyenko D, Mahanta N, Manion H, Naseem S, Dairi T, Begley TP |
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| Title |
Novel enzymology in futalosine-dependent menaquinone biosynthesis. |
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| Journal |
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| LinkDB |
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