KEGG   REACTION: R03546
Entry
R03546                      Reaction                               
Name
carbamate hydro-lyase;
cyanate hydratase;
cyanate C-N-lyase
Definition
Cyanate + H+ + HCO3- <=> CO2 + Carbamate
Equation
Comment
first step of two-step reaction (see R10079, R03546+R07316)
bicarbonate is recycled (see R10092)
Reaction class
RC00952  C01417_C01563
RC02807  C00011_C00288
Enzyme
Pathway
rn00910  Nitrogen metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.104
     R03546  Cyanate + H+ + HCO3- <=> CO2 + Carbamate
Orthology
K01725  cyanate lyase [EC:4.2.1.104]
Reference
1  [PMID:3110153]
  Authors
Johnson WV, Anderson PM.
  Title
Bicarbonate is a recycling substrate for cyanase.
  Journal
J Biol Chem 262:9021-5 (1987)
Reference
2  [PMID:7947823]
  Authors
Anderson PM, Korte JJ, Holcomb TA.
  Title
Reaction of the N-terminal methionine residues in cyanase with diethylpyrocarbonate.
  Journal
Biochemistry 33:14121-5 (1994)
DOI:10.1021/bi00251a022
Other DBs
RHEA: 17404 18492
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