Entry
Name
L-aspartate 4-semialdehyde:1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate methylglyoxaltransferase
Definition
L-Aspartate 4-semialdehyde + 6-Deoxy-5-ketofructose 1-phosphate <=> 2-Amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid + Hydroxypyruvaldehyde phosphate
Equation
Comment
possibly two-step reaction (aldehyde-lyase x2)
Reaction class
Enzyme
Pathway
rn00400 Phenylalanine, tyrosine and tryptophan biosynthesis
rn01110 Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201 ]
2. Transferase reactions
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.10
R08568 L-Aspartate 4-semialdehyde + 6-Deoxy-5-ketofructose 1-phosphate <=> 2-Amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid + Hydroxypyruvaldehyde phosphate
BRITE hierarchy
Orthology
K16306 fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10 ]
Reference
Authors
Morar M, White RH, Ealick SE.
Title
Structure of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid synthase, a catalyst in the archaeal pathway for the biosynthesis of aromatic amino acids.
Journal
Other DBs
LinkDB
All DBs